National Alzheimers Coordinating Center

Normative data for the UDS3 neuropsychological batteries

Uniform Data Set v3.0 — Form C1

MMSE

Weintraub S, Salmon D, Mercaldo N, et al. The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychological test battery. Alzheimer Dis Assoc Disord. 2009;23:91-101.

Shirk SD, Mitchell MB, Shaughnessy LW, et al. A web-based normative calculator for the Uniform Data Set (UDS) neuropsychological test battery. Alzheimers Res Ther. 2011;3:32.

Logical Memory IA — Immediate

Weintraub S, Salmon D, Mercaldo N, et al. The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychological test battery. Alzheimer Dis Assoc Disord. 2009;23:91-101.

Shirk SD, Mitchell MB, Shaughnessy LW, et al. A web-based normative calculator for the Uniform Data Set (UDS) neuropsychological test battery. Alzheimers Res Ther. 2011;3:32.

Benson Complex Figure Copy — Immediate

Possin KL, Laluz VR, Alcantar OZ, Miller BL, Kramer JH. Distinct neuroanatomical substrates and cognitive mechanisms of figure copy performance in Alzheimer's disease and behavioral variant frontotemporal dementia. Neuropsychologia. In press

Contains a normative sample of 94 subjects, age 63 on average.

Digit Span Forward

Weintraub S, Salmon D, Mercaldo N, et al. The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychological test battery. Alzheimer Dis Assoc Disord. 2009;23:91-101.

Shirk SD, Mitchell MB, Shaughnessy LW, et al. A web-based normative calculator for the Uniform Data Set (UDS) neuropsychological test battery. Alzheimers Res Ther. 2011;3:32.

Digit Span Backward

Weintraub S, Salmon D, Mercaldo N, et al. The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychological test battery. Alzheimer Dis Assoc Disord. 2009;23:91-101.

Shirk SD, Mitchell MB, Shaughnessy LW, et al. A web-based normative calculator for the Uniform Data Set (UDS) neuropsychological test battery. Alzheimers Res Ther. 2011;3:32.

Category Fluency

Weintraub S, Salmon D, Mercaldo N, et al. The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychological test battery. Alzheimer Dis Assoc Disord. 2009;23:91-101.

Shirk SD, Mitchell MB, Shaughnessy LW, et al. A web-based normative calculator for the Uniform Data Set (UDS) neuropsychological test battery. Alzheimers Res Ther. 2011;3:32.

Trail Making Test

Weintraub S, Salmon D, Mercaldo N, et al. The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychological test battery. Alzheimer Dis Assoc Disord. 2009;23:91-101.

Shirk SD, Mitchell MB, Shaughnessy LW, et al. A web-based normative calculator for the Uniform Data Set (UDS) neuropsychological test battery. Alzheimers Res Ther. 2011;3:32.

Logical Memory IIA — Delayed

Weintraub S, Salmon D, Mercaldo N, et al. The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychological test battery. Alzheimer Dis Assoc Disord. 2009;23:91-101.

Shirk SD, Mitchell MB, Shaughnessy LW, et al. A web-based normative calculator for the Uniform Data Set (UDS) neuropsychological test battery. Alzheimers Res Ther. 2011;3:32.

Benson Complex Figure Recall

Possin KL, Laluz VR, Alcantar OZ, Miller BL, Kramer JH. Distinct neuroanatomical substrates and cognitive mechanisms of figure copy performance in Alzheimer's disease and behavioral variant frontotemporal dementia. Neuropsychologia. In press

Contains a normative sample of 94 subjects, age 63 on average.

Boston Naming Test

Weintraub S, Salmon D, Mercaldo N, et al. The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychological test battery. Alzheimer Dis Assoc Disord. 2009;23:91-101.

Shirk SD, Mitchell MB, Shaughnessy LW, et al. A web-based normative calculator for the Uniform Data Set (UDS) neuropsychological test battery. Alzheimers Res Ther. 2011;3:32.

Verbal Fluency: Phonemic Test

Published norms are not available at this time.

Uniform Data Set v3.0 — Form C2

MoCA

Nasreddine ZS, et al., The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc. 2005;53:695-699.

Suggests scores less than or equal to 26 as not normal. Also on the MoCA website.

Rossetti HC, et al., Normative data for the Montreal Cognitive Assessment (MoCA) in a population-based sample. Neurology. 2011;77: 1272-1275.

Raises caveats about using standard cut-offs in under-represented samples.

Craft Story 21 Recall — Immediate

Published norms are not available at this time. The equivalency tables from the Crosswalk Study can be used to better understand the distribution of scores; however, they should not be used to set normative cutoffs. After sufficient data have accumulated, members of the Neuropsych Working Group will establish ADC-specific scores on normal individuals that can serve as norms for UDS subjects.

Benson Complex Figure Copy — Immediate

Possin KL, Laluz VR, Alcantar OZ, Miller BL, Kramer JH. Distinct neuroanatomical substrates and cognitive mechanisms of figure copy performance in Alzheimer's disease and behavioral variant frontotemporal dementia. Neuropsychologia. In press

Contains a normative sample of 94 subjects, average age 63.

Number Span Test: Forward

Published norms are not available at this time. The equivalency tables from the Crosswalk Study can be used to better understand the distribution of scores; however, they should not be used to set normative cutoffs. After sufficient data have accumulated, members of the Neuropsych Working Group will establish ADC-specific scores on normal individuals that can serve as norms for UDS subjects.

Number Span Test: Backward

Published norms are not available at this time. The equivalency tables from the Crosswalk Study can be used to better understand the distribution of scores; however, they should not be used to set normative cutoffs. After sufficient data have accumulated, members of the Neuropsych Working Group will establish ADC-specific scores on normal individuals that can serve as norms for UDS subjects.

Category Fluency

Weintraub et al. The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychological test battery. Alzheimer Dis Assoc Disord. 2009;23:91-101.

Shirk SD et al. A web-based normative calculator for the Uniform Data Set (UDS) neuropsychological test battery. Alzheimers Res Ther. 2011;3:32.

Trail Making Test

Weintraub S, Salmon D, Mercaldo N, et al. The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychological test battery. Alzheimer Dis Assoc Disord. 2009;23:91-101.

Shirk SD, Mitchell MB, Shaughnessy LW, et al. A web-based normative calculator for the Uniform Data Set (UDS) neuropsychological test battery. Alzheimers Res Ther. 2011;3:32.

Craft Story 21 Recall — Delayed

Published norms are not available at this time. The equivalency tables from the Crosswalk Study can be used to better understand the distribution of scores; however, they should not be used to set normative cutoffs. After sufficient data have accumulated, members of the Neuropsych Working Group will establish ADC-specific scores on normal individuals that can serve as norms for UDS subjects.

Benson Complex Figure Recall — delayed

Possin KL, Laluz VR, Alcantar OZ, Miller BL, Kramer JH. Distinct neuroanatomical substrates and cognitive mechanisms of figure copy performance in Alzheimer's disease and behavioral variant frontotemporal dementia. Neuropsychologia. In press

Contains a normative sample of 94 subjects, age 63 on average.

Multilingual Naming Test (MINT)

Ivanova I, Salmon DP, Gollan TH. The multilingual naming test in Alzheimer's disease: clues to the origin of naming impairments. J Int Neuropsychol Soc. 2013;19:272-83.

See Table 3 for information on subjects with normal cognition. The mean proportion correct was .92 with a standard deviation of .08. This translates to a mean score of 29.44 out of 32 possible points on the MINT.

Verbal Fluency: Phonemic Test

Published norms are not available at this time.