NACC tissue location request
NACC has gathered data since 1984 on various tissues stored at the Alzheimer's Disease Centers (ADCs) for their subjects. Some tissues are from autopsy, and some are from living subjects. Postmortem specimens include brain tissue (frozen, formalin-fixed, and paraffin-block) and CSF. Antemortem specimens include DNA, serum, and CSF. Clinical and pathological features characterizing the subjects who supplied tissue are defined in the MDS, UDS, or NP data forms or guidebooks.
Please note that the tissues reported as stored at the ADC may not reflect the Center’s current inventory, as tissue samples may be depleted over time or be unavailable for sharing. Thus, all estimates of availability are rough estimates.
To perform a simple web-based query of specimens that may be available, use the NACC Tissue Query. The Tissue Query generates sample size estimates of tissue availability based on your criteria — for example, demographic characteristics or cognitive status.
If you wish to go beyond the capabilities of the Tissue Query and locate ADCs where specific tissues may be housed, please use the Tissue Location Request Form to describe the specimens of interest. NACC will contact you to discuss the details of your request. If the specimens you need are reported to be available, NACC will then put you in contact with the ADC(s) that hold the specimens. From that point, you will negotiate directly with the ADC(s) to determine whether and how material transfer agreements may be established, which specimens are available in sufficient quantities to share, and any costs associated with their transfer.