Two ways to locate tissue
NACC gives you two ways to locate biospecimens at the Alzheimer's Disease Centers:
- Search on your own using the NP & BIOSPECIMEN RESOURCE LOCATOR TOOL
- Submit a TISSUE LOCATION REQUEST for NACC's assistance
Keep reading for a brief description of the two approaches.
NACC's NP & Biospecimen Resource Locator Tool allows the user to independently check whether tissue is available at an Alzheimer's Disease Center, filtering by tissue type, neuropathologic disease, and so on. The information in the Resource Locator Tool comes from periodic surveys of the ADCs.
When you submit a tissue location request, you provide NACC with a brief description of the type(s) of tissue you seek and any parameters needed to narrow your selection. Drawing mainly from data in NACC's NP Data Set, NACC will search for Alzheimer's Disease Centers that may have your target tissues, and then put you in touch with those Centers.
NACC biospecimen data: History and background
NACC has gathered data since 1984 on various tissues stored at the Alzheimer's Disease Centers (ADCs) for their subjects. Some tissues are from autopsy, and some are from living subjects. Postmortem specimens include brain tissue (frozen, formalin-fixed, and paraffin-block) and CSF. Antemortem specimens include DNA, serum, and CSF. Clinical and pathological features characterizing the subjects who supplied tissue are defined in the MDS, UDS, or NP data forms or guidebooks.
Please note that the tissues reported as stored at the ADC may not reflect the Center’s current inventory, as tissue samples may be depleted over time or be unavailable for sharing. Thus, all estimates of availability are rough estimates.