Evaluation of the Neuropathologic Cerebrovascular Sequelae of Antipsychotic Use

Traumatic Brain Injury Dementia

Factors associated with conversion to mild cognitive impairment or Alzheimer's
disease in persons with subjective memory complaints

The Relationships Among Body Mass Index, Alzheimer's Disease Neuropathology,
and Cerebrovascular Disease

Alzheimer early predication using Big Data analysis.

Impact of Depression Symptoms on Executive Functioning and Processing Speed in
Older Adults

Behavioral Reserve in MCI and AD

Neuropsychiatric Presentations of Dementia According to Age of Onset

Disparities in the trajectory of cognitive function among older Asians, African

Mathematical modeling of frailty, cognition, and neuropathology

Association of Declining Cognitive Status and Nighttime Behaviour Prevalence
Along the Spectrum of Alzheimer's Disease Severity

Development of Composite Cognitive Endpoints for Presymptomatic AD Trials

Subjective Memory Complaints in Cultural Majority and Minority Groups

Barriers to engagement in genetic research

The effects of age on atrophy rates in controls, MCI and AD subjects.

Characterizing differences in NPS between FTLD tau-positive group and the FTLD
tau-negative group.

Neuropathological Agreement with the Clinical Diagnosis of Alzheimer's Disease

The NACC Uniform Data Set

The National Alzheimer's Coordinating Center: Development of the MRI, PET and

The National Alzheimers Coordinating Centers Data Submissions System and
Database

UDS FTLD System Abstract

Body Mass Index, Weight Change, and Clinical Progression in MCI and AD

Characterizing PD-MCI in the NACC sample

Clinical characteristics associated with neuropathological Lewy body disease
subtypes among nondemented subjects in the Uniform Data Set

Clinical diagnoses in those with primary age related tauopathy and AD
neuropathology

Comparison of Neuropsychological Test Scores among English and Spanish Speakers

Late life systolic blood pressure, body mass index, and heart rate, and
Alzheimers neuropathology among those without dementia before autopsy

Pulse Pressure and clinical and neuropathological AD and CVD

Alzheimers Disease and toxicity exposure: a gene-environment interactions

Estimation of APOE risk curves for the Alzheimer Prevention Initiative

Is High Educational Attainment Over-represented Among Patients with a
clinically-diagnosed frontotemporal lobar degeneration-spectrum disorder

Exploring possible risk factors associated with frontotemporal dementia and
primary progressive aphasia

Medication Use in Frontotemporal Lobar Degeneration (FTLD) as compared to
Alzheimers Disease (AD)

Characterizing subject informants in NACCs UDS database

Prevalence of cerebral amyloid angiopathy in NACC NP dataset

Prevalence of mixed neuropathologies in autopsied older adults and associations

Quantitative Imaging to Detect Regional Neurodegeneration in AD and other
Disorders

Consensus Diagnosis and Predictors of Diagnostic Accuracy in the National
Alzheimer's Disease Centers

Specific Bilingual Background and Risk of Cognitive Impairment

Common Functional Deficits in MCI and Dementia

Repeated Measure in Subsequent Population Data to Confirm Evidence that High
Educational Attainment is Over-Represented among Patients with Frontotemporal

Sleep disturbance, vascular burden and prospective cognitive decline in
Cognitive Normal and MCI Elderly

The DIAN and NACC UDS Comparison Study

Computerizing the conversation: A codified approach to consensus diagnosis

Cognitive and imaging profiles associated with vascular pathologies in dementia

Early signs of dementia in bipolar disorder

Operationalizing impaired performance in neuropsychological assessment: A
comparison of the use of published versus sample-bases normative data

Predictors of Cognitive Improvement in Persons with Cognitive Impairment

Machine Learning Approach to Predict Dementia Progression

Investigating the Genetic Contribution to Functional Brain Changes in

Association of Lewy body pathology with UPDRS motor scores, Neuropsychiatric
symptoms, and Depression scores among persons with Neuropathological AD

Psychometrics Properties of the Geriatric Depression Scale in the Cognitively

Beside Still Waters: Alzheimers disease in the African American Community

The effects of depression on functional impairment in Lewy body dementia

Principal Factor Analysis for Neuropsych Battery

Relating NPI-Q Scores to the Pathologic Burden of AD Based on NACC Data

Assessing the impact of delays in onset of mild cognitive impairment on the
epidemiology of Alzheimer's disease

Assessing the impact of delays in onset of mild cognitive impairment on the

Statin Use, Incidence of AD, and Neuropsychological Correlates: An Analysis of

Neuropsychiatric Presentations of Alzheimer's Disease at Age of Onset that
Impact Cognitive and Daily Life Functioning in later life.

Clinical phenotype of dementia after traumatic brain injury (TBI).

UDS 3 Norms

Characteristics of cognitively impaired Spanish-speaking individuals of
Hispanic origin in the NACC database

Missing Data and the Identification of Optimal Predictors of Conversion to AD

Relationship of cardiovascular risk factors to dementia subtypes

Robust Norms for UDS Cognitive Test Battery and Utility of Individual Tests

The relationship of blood pressure to cognitive changes and brain volume
changes in controls, MCI and AD patients

Neuroimaging Correlates of Delusions in Alzheimer's Disease and Related
Dementias

Decision quality and the use of cardiac rhythm regulating devices in adults

Genetic, clinical and environmental factors and cognitive decline in AD

Predicting disease susceptibility using Machine Learning algorithms.

Validation of non-amyloid, non-Tau CSF biomarkers for Alzheimer's disease

Empirical Examination of Mismatched In-Vivo and Neuropathological Alzheimer's
Disease Diagnosis

Measurement invariance of delta

Rates of abnormal test scores in patients with and without neurodegenenerative
diseases

The influence of brain pathology, APOE genotype, and cognitive reserve on
longitudinal cognitive and functional decline.

Neuropathological correlates of mild cognitive impairment

Stability and severity of psychiatric symptoms in relation to cognitive,

Subjective Memory Complaint and Cognitive Aging

Rate of functional decline in AD, VaD and DLB

Sex differences in rate of progression of three dementia types.

Stability of Dementia Diagnosis among UDS Participants

Impact of different blood pressure cutoffs on cognitive functioning and disease

Predictors of survival in Lewy body disease

Differences in pathological substrate underlying dementia in African Americans
and Caucasians

Genetic Architecture of Rate of Decline in Alzheimers Disease

Assessing disease progression among Alzheimer's disease patients with adult
child study partners

Choosing Alzheimers disease prevention clinical trial populations.

A reliable, standardized general cognitive performance measure in NACC

Body Mass index Change in Alzheimers Disease Patients

Evaluating sex differences and vascular morbidities in relation to global

UPPGRAID: Understanding and Predicting Personalized Growth Rate curves to Aid
Individual prognosis in late-onset Dementia

Atrial Fibrillation in AD Patients

The Vascular Component of Behavioral Variant Frontotemporal Dementia

Patterns of antidepressant use in clinical progression from normal cognition to

Cholinesterase Inhibitor Use and Cognitive Decline in Mild Cognitive
Impairment and Mild Dementia due to Alzheimer Disease

Modelling the natural disease progression of Alzheimer's disease

Latent Class Analysis of MCI Using Longitudinal Clinical Features

Identification of Cognitive Endophenotypes

Indices of Reliable Change Over Time

The NACC MRI Database

Type II Diabetes and the risk of cognitive decline: A Multi-Center Cohort Study

Tobacco and Alcohol Use and Associated Cognitive Decline in the Older Adult
Population

Non-homogeneous Markov process models for rate of conversion to MCI

Risk Factors for Apathy in AD

APOEe2 is associated with milder clinical and pathological Alzheimer
disease

Evaluation of inclusion exclusion criteria in clinical trial design

Impact of Cardiovascular Risk Factors on Cognitive Scores Over Time

Identification of endophenotypes in frontotemporal degeneration

Early-Onset AD: Clinical and Genetic Analyses

Sensitivity and specificity of the Multilingual Naming Test (MINT) in

Vascular risk factors of cognitive aging

CSF biomarkers and cognitive function in primary age-related tauopathy and
Alzheimer's dementia

Biomarker and Genetic Moderators of Cognitive and Daily Life Functioning in
Clinical Neurological Disorders

The GDS and its measurement validity in African American populations

A Cross-Sectional and Longitudinal Comparison of Diagnostic Accuracy of the

Subjective memory complaints in the preclinical presentations of

Clinicopathologic correlation in FTLD

Heart failure predicts cognitive dysfunction after adjusting for APOE factors

Trajectory of Dementia

Comparing variations of cognitive composites across the early Alzheimer?s
disease spectrum

Neuroanatomical and neuropsychological correlates of abnormal feeding in FTD

Measuring memory performance using the Montreal Cognitive Assessment and the

Integrative Biology and Stratification of Dementia

The influence of smoking history on the phenotype and pathology of dementia

United Parkinson's Disease Rating Scale (UPDRS) Data Analyses

Neuropsychological predictors of judgment/problem-solving in patients with HIV

Early diagnosis of Alzheimer's disease

Establishing preclinical cognitive and risk profiles associated with the
development of Alzheimer's disease

Diagnostic Accuracy of Pathologically Confirmed AD in the NACC UDS:
Computational Classification Using Psychometric Measures

The Contribution of Neuropsychological Performance, Behavioral and Functional
Measures in High- Lowlikelihood Alzheimer's Disease Profiles

Towards a Unified Language of Cognition: Defining Domains, Normality, and
Change

Evaluation of FTLD module data

The utility of a language domain rating and a behavior-comportment and

Lipophilic vs. Hydrophilic Statin Exposure and Post-Mortem Neuropathology

Characterizing UDS Participants who Revert from MCI to Normal Cognition

Education, cognitive function, and severity of neuropathology in AD

Observation of neuropsychiatric Symptoms across Dementia Syndromes

Neuropsychological, Motor, and Pathological Evaluation of the Primary
Progressive Aphasias

Comparison of motor symptoms in MCI by underlying disease process

Lewy body pathology and clinical diagnoses in the NACC database

Primary Neuropathologic Diagnosis and Co-Occurrence of Other Neuropathologic
Features: Results from the NACC database

Standardized data collection and diagnostic formulation for FTLD Clinical Exam:

Applying 'growth curves' to age-associated cognitive decline: an innovative
method to help determine normal vs. abnormal longitudinal cognitive changes in

Relation of Diabetes Medications to Cognitive and Neuropathological Findings in

Novel magnetic resonance imaging (MRI) based biomarkers for cerebrovascular

Inappropriate Drug Use among Community-Dwelling Elders with Dementia

'Phase II and III trial simulators: Using mathematical, computational and
statistical techniques to simulate trial design for new products in the

Age-associated Memory Impairment as a predictor of future cognitive decline

Pathological-Behavioral correlations in FTD spectrum disorders

Neuropsychiatric Syndromes in Dementia: Evolution, Risk Factors and Outcomes

COGNITIVE IMPAIRMENT PROGRESSION ANALYSIS USING AGENT-BASED SIMULATION APPROACH

Traumatic Brain Injury in Early versus Late Onset Alzheimer's Disease

Alzheimer's Disease in Under-represented Populations

Risk of Self-Reported Head Injury in the Development of Mild Cognitive
Impairment and Alzheimer's Disease

Depression and Insight

Normative data for the neuropsychological assessment from the Alzheimers

Substance abuse and neuropsychiatric symptoms

Clinically Unrecognized Cases of Prion Disease in the National Alzheimer's

Mild Cognitive Impairment in Older, Rural Dwelling Adults

Determinants of Judgment and Problem Solving

Functional and Cognitive Assessments and their Relationship to Alzheimer's

Ethnic Differences in Alzheimer's Disease Survival and Pathology

Antithrombotic medication use and dementia incidence among mild cognitive
impairment patients with atrial fibrillation

Cholinesterase Inhibitors and Memantine Use in the National

Dysexecutive function in Alzheimer's Disease: A genetic and neuropsychologic

Longitudinal evaluation of dysexecutive vs. amnestic Alzheimer's

The relationship between neuropathology and expression of dementia in the

Screening for Mild Cognitive Impairment and Alzheimer?s Disease among Minority
Populations using the Montreal Cognitive Assessment

Development and Stability of Delusions Across the Spectrum from Normal Aging to

Role of Metabolic Syndrome on the Decline of Cognitive Abilities and
Progression to Mild Cognitive Impairment and Alzheimer's Disease

Identifying functional milestones in disease progression in frontotemporal
dementia

Heterogeneity of Informant-Reported Functional Impairments in Older Adults

Genetic differences between symptomatic and asymptomatic persons with AD
neuropathologic change

Trends in performance on neuropsychological tests for asymptomatic persons with

An investigation of the impact of neurocognitive disorders on women

Evaluating the magnitude of potentially inappropriate medication prescribing
and its impact on mortality in the NACC cohort

Evaluation of use and risks associated with bladder antimuscarinics

APOE e4 and clinical progression in Parkinson's disease

Variation among different measurements of cognitive decline

Examining cognitive thresholds in a population of cognitive normal participants

Accuracy of Clinical Diagnosis in Dementia

The Uniform Data Set (UDS): Clinical and Cognitive Variables and Descriptive

Factors Influencing Lumbar Puncture Participation in Alzheimer Research

Impact of education and vascular injuries on development of dementia

Pathology of Rapid Cognitive Decline

Hippocampal sclerosis of aging in NACC

Clinicopathological correlation in Dementia with Lewy bodies (DLB)

Evaluation of association between sulfonylurea use and hippocampal sclerosis
pathology

Operationalization of Hypertension and Diabetes in the Aged Population Using
NACC Database

Segregation and integration of cognitive domains in healthy and pathological
aging

Estimating the Cost of Delayed Treatment for Alzheimers Disease

Cognitive Reserve and Executive Cognition in Frontotemporal Dementia

Comparative utility of neuropsychological and functional measures over the
course of frontotemporal dementia

Clinical Characterization and Outcome of Subjects with Mild Cognitive
Impairment

Description of UDS MCI, pre-MCI, and Control Subjects

Baseline study factors the predict dropout in the UDS

Demographic, Clinical and Genetic Characteristics of symptomatic and

The role of cognitive reserve in neuropathological FTD

Speed of Quartile of survival times in AD subjects after death

Variability in clinical trajectory within AD, FTD, LBD, VD, HSD, CJD and mixed
dementia diagnostic categories.

Misdiagnosis of Alzheimer?s disease: Inconsistencies between clinical diagnosis

Neuroimaging Correlates of Delusions in Alzheimer's Disease and Related
Dementias

ACE Inhibitor, Angiotensin II Receptor Blockers, and ApoE4 on Alzheimer's

Identifying factors that substantially impact AD or dementia progression

Pathology of subjects clinically diagnosed with vascular dementia

Neuropathological Changes in Dementia in Patients with Co-morbid Depression

Clinical, cognitive and neuropathological characteristics of the NACC Latino
Cohort: Evidence for differential risk factors and implications for diagnosis.

Neuropathological assessments of fibrillar amyloid burden in APOE e4 carriers
and non-carriers with the clinical diagnosis of Alzheimer's dementia

Interaction between APOE and life risk factors on dementia

Neuropsychological and demographic factors affecting the conversion to

Clinical and Cognitive Predictors of Severe Cerebral Amyloid Angiopathy

Demographic, genetic, and pathological correlates of Cerebral Amyloid
Angiopathy

Frequency of Lewy Body and other pathologies in autosomal dominant AD relative

Explicit estimates for cell counts and modeling the missing data indicators in
three-way contingency table by log-linear models

Comparison between clinical-pathological phenotype between dominantly-inherited

Education, The Cognitive Reserve Hypothesis, and Alzheimer's Disease Without
Dementia

Diagnostic Stability of Transitional States in a Diverse Population

Sex-specific patterns and differences in the core modalities associated with
Alzheimer's disease

Affective symptoms and vascular factors are more prevalent in non-amnestic
than amnestic Mild Cognitive Impairment (MCI)

AD Neuropathology in those with APOE e2/e2 alleles

The effect of statins on the neuropathology of dementia due to Alzheimer's

Verification Bias

EXPLORING MULTIDIMENSIONAL COMPLEXITY IN THE DEMENTIAS: THE ASSOCIATION OF

Diabetes and Alzheimers Disease in the Uniform Data Set

Cross-cultural Differences in the Diagnosis of Dementia

Predicting dementia symptom progression after diagnosis using an

TBI and Age of Dementia Diagnosis in an Autopsy-Confirmed Sample

The National Alzheimer's Coordinating Center: Querying the Database and
Requesting Data

The etiology of long term stable Mild Cognitive Impairment

Outcomes associated with receiving an early versus late diagnosis of

Clinicopathologic correlation: Alzheimer mimics

Cross-sectional and longitudinal relations between cardiovascular health and
cognitive function in minority elders

Genetic variability and cardiovascular disease (CVD) burden as predictors of
cognition in African American elders

Evaluating whole brain health using Brain Atrophy and Lesion Index:
validation using large datasets

Transitions and pharmaceutical use by CDR level in Alzheimers disease.

The Placebo Group Simulation Approach (PGSA): Predicting Decline in Patients

Comparison of standardized and non-standardized administration of WMS Logical
Memory Delayed in a population of older adults with probable Alzheimers

Neuropathological and subject-characteristic correlates of cognitive reserve in

Vascular and behavioral symptoms predict progression from healthy aging to
dementia

Proposal to Use UDS/NACC Data to Further Study Depression and Progression to

Variations across Centers

Brain-behavior relationships in Cognitively Healthy and Mild Cognitively

Clinical and pathological characteristics of hippocampal sclerosis dementia

Anticholinergic Drug Use And Risk Of Cognitive Decline And Dementia Among Older

Assessing Neuropsychiatric Symptoms in Patients with Alzheimer's disease and

Examining the Association between Neuropsychiatric Symptoms, Hypertension,
Hypercholesterolemia, and Diabetes in Alzheimer's disease

Determining specific functional declines associated with progression from mild

Investigating the Role of Traumatic Brain Injury as a Risk Factor for
Frontotemporal Lobar Degeneration

Patterns of Functional Decline in Clinical Subtypes of Frontotemporal Dementia

The Alzheimers Disease Centers Uniform Data Set(UDS):Using various algorithms
to predict Dementia types with MMSE and CDR

Utility of the Functional Activities Questionnaire in Distinguishing Between
Mild Cognitive Impairment and Mild Alzheimer's Disease

Associations of neuropathology and apolipoprotein E genotype with dementia in
the Oldest Old compared to younger-old age groups

Rheumatoid arthritis, inflammation treatment, and Alzheimer?s disease: a
cross-sectional descriptive study using the NACC database

Clinicopathological correlation of psychosis and brain vascular burden in
Alzheimer's disease

Effect of mixed neuropathologies on profile and cognitive change in dementia

Analysis of genetic susceptibility loci underlying Alzheimer's disease with
additional feature

Effect of TBI on cognition and its decline

Specifically, we propose to apply a longitudinal factor analysis model to a
variety of neuropsychological tests and estimate a smooth cognitive trajectory.

Prevalence of Seizures, Tremor and Gait Disturbances in AD

Does white matter degeneration occur early in the progress of Alzheimer's

Association between TAU haplotypes and head injury in probable AD cases -
Replication Sample Request

Assessment of Spanish-speakers in English vs Spanish

Efficient Data Mining Algorithms in Handling Alzheimer's Disease

Comparing Neuropsychological Performance in Patients with early signs of

Role of age in untreated vs treated sleep apnea

Causal inference with truncation by death in observational study

Evaluate Diagnostic Accuracy in the Absence of a Gold Standard

Semi-parametric model for interval censored data with a cured subgroup

Frequency of e4 allele in frontotemporal dementia with AD neuropathology

Measurement and characterization of distinctive clinical phenotypes using the
Frontotemporal Lobar Degeneration Module (FTLD-MOD) of the National Institute

Racial differences on neuropsychological test performance

Does loss of a spouse impact cognitive trajectory in normal controls, MCI and

Characterizing MCI subjects who remained cognitively stable

Predicting trajectories of MCI with medical, demographic, genetic, and
neuropsychological data

Do Specific Symptoms on the Geriatric Depression Scale Predict Incident MCI or

Retrospective study of clinical biomarkers of prodromal Dementia with Lewy
Bodies

The Combined Influence of Vascular Risk Factors and Alzheimers Disease on
Cognition, and the Role of Vascular Neuropathology in that Relationship.

A Big Data approach to identify subtypes of Alzheimer's disease AD Drug

Network features associated with the progression of Alzheimer's disease

Analysis of binary long data in multi-center studies with missing covariates

Applied Missing Data Analysis in Health Sciences

Estimate the ROC curve and its area in the presence of nonignorable
verification bias

Dissociable Facets of Executive Dysfunction and Association with Preclinical
Alzheimers Disease

Relationship between apathy and depression