NACC Research

List of all Proposals



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A semi-Markov model for multi-state and interval-censored data: An application
of the cognitive states present in the Uniform Data Set


Jeremiah Aakre       ADC       Mayo Clinic ADRC
Data File Sent



A Bayesian Analysis of the Effect of Statins on Cognitive Impairment in
Alzheimer's Patients


Robert Aarhus       Non-ADC       George Mason University
Data File Sent



Evaluation of the Neuropathologic Cerebrovascular Sequelae of Antipsychotic Use


2013 Erin Abner       ADC       University of Kentucky
Abstracts = 1



The development of a total score for the National Alzheimers Coordinating


Erin Abner       ADC       U of Kentucky
In Press



Analysis of GDS Data from the Uniform Data Set


Kathyrn Betts Adams       ADC       Case Western
Completed - No Publications
Proposal is complete.



BLUP Estimates of Mixed Model for Alzheimer Data


Serpil Aktas       Non-ADC       Stony Brook University
Completed - No Publications
Proposal is complete.



Longitudinal analysis of APOE and gender mediated conversion risk in
preclinical AD


2013 Andre Altmann       Non-ADC       Stanford University
In Press



Behavioral Reserve in MCI and AD


2010 Liana Apostolova       Junior       UCLA
Papers = 1 Abstracts = 3
Proposal is complete.



Characteristics of Neuropsychiatric Presentations of CJD and Other Prion


Brian Appleby       ADC       Johns Hopkins
Completed - No Publications
Proposal is complete.



Neuropsychiatric Presentations of Dementia According to Age of Onset


2010 Brian Appleby       ADC       Johns Hopkins
Abstracts = 1



Mathematical modeling of frailty, cognition, and neuropathology


Joshua Armstrong              Dalhousie University
Data File Requested



Behavioral presentation and manifestation of depression in clinically depressed


Edmon Artinyan       Non-ADC       Loma Linda University
Data File Sent



Compare characterization of clinical course across different tests used to


Alireza Atri       ADC       Bedford VAMC Massachusetts General Hospital
Data File Sent



Statistical methods for tracking clinical course


Alireza Atri       ADC       Bedford VAMC Massachusetts General Hospital
Data File Sent



Development of Composite Cognitive Endpoints for Presymptomatic AD Trials


2013 Napatkamon Ayutyanont       ADC       Arizona ADC
Abstracts = 1



Aggregate effects of vascular risk on neuropathology across the spectrum from
Alzheimer's disease to vascular dementia


Katherine Bangen       ADC       University of California, San Diego
Data File Sent



The neuropathology of empirically-derived mild cognitive impairment subtypes


Katherine Bangen       ADC       University of California, San Diego
Data File Sent



Compare UDS to other Data Sets


Sandra Barral       ADC       Columbia
Completed - No Publications
Proposal is complete.



Memory performance in ADC/NACC data


Sandra Barral Rodriguez       ADC       Columbia
Data File Sent



Effect of MMSE score on health outcomes among Alzheimers patients


Onur Baser       Non-ADC       The University of Michigan
Completed - No Publications
Proposal is complete.



Neuropathological Agreement with the Clinical Diagnosis of Alzheimer's Disease


2011 Tom Beach       ADC       Arizona
Papers = 1 Abstracts = 1



Description of the Uniform Data Set Database


2007 Duane Beekly       NACC       NACC
Papers = 1
Proposal is complete.



The NACC Uniform Data Set


2010 Duane Beekly       NACC       University of Washington
Abstracts = 1
Proposal is complete.



The National Alzheimers Coordinating Centers Data Submissions System and
Database


2004 Duane Beekly       NACC       NACC
Papers = 1 Abstracts = 1
Proposal is complete.



UDS FTLD System Abstract


2012 Duane Beekly       NACC       NACC - University of Washington
Abstracts = 1
Proposal is complete.



Association of the frailty syndrome and risk of developing Alzheimer's disease


Susan Bell       Non-ADC       Vanderbilt Univeristy Medical Center
Data File Sent



Body Mass Index, Weight Change, and Clinical Progression in MCI and AD


2014 Lilah Besser       NACC       NACC
Papers = 1 Abstracts = 1



Characterizing PD-MCI in the NACC sample


2014 Lilah Besser       NACC       NACC
Abstract Submitted



Comparison of Neuropsychological Test Scores among English and Spanish Speakers


2012 Lilah Besser       NACC       University of Washington - NACC
Abstracts = 1



Elevated pulse pressure (PP), cognitive impairment and decline, and vascular
and AD neuropathology


2013 Lilah Besser       NACC       
Abstracts = 1



Late life BMI, Weight change, and AD pathology


Lilah Besser       NACC       
Data File Sent



Neuropathology and Functonal, Cognitive, and Neuropsychiatric symptoms
in Misdiagnosed AD


Lilah Besser       NACC       NACC
Data File Sent



Dementia outcomes through predictive modeling techniques


Amor Bhalla       Non-ADC       Arizona State Univeristy
Data File Requested



Multivariate analysis GWAS analysis to determine genetic variants associated
with endophenotypes of Alzheimer's disease


Priya Bhatt       Non-ADC       University of Southern California
Data File Requested



Alzheimers Disease and toxicity exposure: a gene-environment interactions


2012 Rhea Bhatta       Non-ADC       Lehigh University
Abstracts = 1



A genome-wide association study of Alzheimer's disease with psychosis


Deborah Blacker       ADC       Mass General
Paper in Prep



Analytic Strategies for the NACC Database


2013 Deborah Blacker       ADC       Mass ADRC
Papers = 1



Sleep Phenotypes by Diagnosis


2011 Donald Bliwise       ADC       Emory
Papers = 1
Proposal is complete.



CDR State Transition Probabilities in Alzheimer's Disease with and without
Cholinesterase Inhibitor Intervention in an Observational Cohort of AD Patients


Lisa Bloudek       Non-ADC       University of Washington
Completed - No Publications
Proposal is complete.



Mild To Moderate Alzheimer's and Co-morbid Conditions


Tracy Blumenfeld       Non-ADC       Rapidtrials
Completed - No Publications
Proposal is complete.



Is High Educational Attainment Over-represented Among Patients with a
clinically-diagnosed frontotemporal lobar degeneration-spectrum disorder


2013 Bradley Boeve       ADC       Mayo Clinic
Abstracts = 1



Association of essential tremor, cognitive dysfunction, and risk of dementia


Aaron Bonner-Jackson       Non-ADC       Cleveland Clinic
Completed - No Publications
Proposal is complete.



Medication Use in Frontotemporal Lobar Degeneration (FTLD) as compared to
Alzheimers Disease (AD)


2010 Adam Boxer       ADC       University of California, San Francisco
Papers = 1 Abstracts = 1



Poor visuospatial performance and poor delayed recall are associated with
biomarkers of Alzheimer disease in patients diagnosed with corticobasal


Clara Boyd       Non-ADC       Columbia University Medical Center
Data File Requested



Characterizing subject informants in NACCs UDS database


2012 Willa Brenowitz       NACC       NACC
Abstracts = 1



Prevalence of cerebral amyloid angiopathy in NACC NP dataset


2013 Willa Brenowitz       NACC       NACC
Abstracts = 1



The associations of social relationships with risk of incident amnestic and


2014 Willa Brenowitz       NACC       
Papers = 1



Consensus Diagnosis and Predictors of Diagnostic Accuracy in the National
Alzheimer's Disease Centers


2013 Kate Bristow       NACC       NACC
Abstracts = 1



Next generation Mendelian genetics in familial Alzheimer disease


Zoran Brkanac       Non-ADC       University of Washington
Data File Sent



Common Functional Deficits in MCI and Dementia


2013 Patrick Brown       Junior       Columbia
Papers = 2
Proposal is complete.



Frontally-Mediated Syndromes in Late Life: An Exploration


Patrick Brown       ADC       Columbia
Data File Sent



Repeated Measure in Subsequent Population Data to Confirm Evidence that High
Educational Attainment is Over-Represented among Patients with Frontotemporal


2013 Marla Bruns       ADC       Mayo Clinic
Abstracts = 1



Development of composite measures for AD clinical trials


Teresa Buracchio       Non-ADC       AbbVie
Data File Sent



Interactions between Behavioral Factors and APOE in predicting Alzheimer???s
Disease


Shanna Burke       Non-ADC       Simmons College
Data File Requested



Visualizing the Impact of Missing Data within Alzheimer's Disease using D3


2013 Randy Burnham       ADC       Washington University in St. Louis
Abstract Submitted



Predictors of Cognitive Improvement in Persons with Cognitive Impairment


Mirnova Ceide       Non-ADC       SUNY Downstate Medical Center
Data File Sent



Causes and disease progression of dementia among Asians


2013 Rosa Chan       Non-ADC       City University of Hong Kong
Papers = 2



APOE Allele Distributions in Variants of Primary Progressive Aphasia


Dorothy Charles       Non-ADC       Princeton University
Data File Sent



Test the reliability of doubly robust estimation with missing response data


2014 Baojiang Chen       Non-ADC       University of Nebraska
Papers = 1



Use of empirical likelihood to calibrate auxiliary information in isotonic


2012 Baojiang Chen       NACC       UW
Papers = 1



Adaptive Medical Diagnosis Expert System (AMDES) for the Early Diagnosis of
Dementia


Allan Chong       Non-ADC       National University of Singapore
Data File Sent



Incidence rates, age of onset, and severity of histopath in
obese vs non-obese subjects. All to be done on neuropath confirmed cases.


Kee Lee Chou       Non-ADC       University of Hong Kong
Completed - No Publications
Proposal is complete.



Smoking, Depression and APOE status on Cognitive Decline


Kee Lee Chou       Non-ADC       University of Hong Kong
Completed - No Publications
Proposal is complete.



Alzheimer's disease (AD) and depression associated with AD


Yulin Chu       Non-ADC       James J. Peters Veterans Affairs Medical Center
Data File Sent



Psychosocial fActors Relevant to brAin DISorders in Europe (PARADISE)


Alarcos Cieza       Non-ADC       IHRS, LMU Munich
Completed - No Publications
Proposal is complete.



Beside Still Waters: Alzheimers disease in the African American Community


2013 Shelytia Cocroft       Non-ADC       Wayne State University, Department of Sociology
Abstracts = 1



Gene Expression Profiling in TDP-43 positive FTD


Concepcion Conjero-Goldberg       Non-ADC       The Litwin-Zucker Alzheimer's Research Center
Completed - No Publications
Proposal is complete.



Neuropsychiatric Symptoms in Alzheimer's Disease


Joesph Cooper       ADC       Northwestern
Completed - No Publications
Proposal is complete.



Validation of the TICS and DQ for Dementia status in the Long Life Family Study


2013 Stephanie Cosentino       ADC       Columbia
Papers = 1



Mapping the Trajectory of Functional Decline in Newly Diagnosed Alzheimer's
Disease


Joseph Coughlin       Non-ADC       Massachusetts Institute of Technology
Data File Sent



Relative contribution of Alzheimer and vascular pathology to brain and
hippocampal atrophy


Howard Crystal       Non-ADC       SUNY Downstate (Brooklyn, NY)
Completed - No Publications
Proposal is complete.



Relating NPI-Q Scores to the Pathologic Burden of AD Based on NACC Data


2010 Jeffrey Cummings       ADC       UCLA
Abstracts = 1



Aging and Health among Older Adults with Traumatic Brain Injury


2013 Kristen Dams-O'Connor       Non-ADC       Mount Sinai School of Medicine
Papers = 1



Late-Onset Depression and Risk of MCI in Cognitively Normal Older Adults


Kara Dassel       ADC       Arizona ADRC
Completed - No Publications
Proposal is complete.



The natural history of FAQ decline in subjects with early AD
and identification of significant covariates of decline.


Allitia DiBernardo       Non-ADC       JohnsonJohnson
Completed - No Publications
Proposal is complete.



Clinical phenotype of dementia after traumatic brain injury (TBI).


2010 Ramon Diaz-Arrastia       ADC       University of Texas Southwestern Medical Center
Papers = 1 Abstracts = 3



Clinical characteristics of early-onset AD


2013 Brad Dickerson       ADC       Massachusetts General Hospital
Paper Submitted



Missing Data and the Identification of Optimal Predictors of Conversion to AD


2013 Maritza Dowling       Junior       U Wisconsin
Abstracts = 1



The role of a mitochondrial protein in axonal mitochondrial motility injury in
Alzheimer???s disease (AD)


Heng Du       Non-ADC       University of Texas, Dallas
Data File Requested



Relationship of cardiovascular risk factors to dementia subtypes


2014 Brittany Dugger       Junior       Arizona
Abstracts = 1



Clinical-Neuropathological Correlates of Hippocampal Sclerosis


Steve Edland       ADC       UCSD
Completed - No Publications
Proposal is complete.



Visit to visit blood pressure variability and cognitive dysfunction validation
in NACC dataset


Noam Epstein       Non-ADC       Pfizer
Data File Sent



Healthy brains in the very old in the NACC path database


Deniz Erten-Lyons       ADC       OHSU
Completed - No Publications
Proposal is complete.



Alzheimers disease risk assessment


Michael Farnum       Non-ADC       Johnson and Johnson
Completed - No Publications
Proposal is complete.



Estimation of treatment effects with propensity score in the presence of
missing outcome data


Han Feng       Non-ADC       Renmin University of China
Data File Sent



Robust Norms for UDS Cognitive Test Battery and Utility of Individual Tests


2012 Steven Ferris       ADC       NYU
Abstracts = 3



Frequency of Frontal Hypometabolism in Autopsy Confirmed AD Subjects


Norman Foster       Non-ADC       University of Utah, Center for Alzheimer's Care
Completed - No Publications
Proposal is complete.



Decision quality and the use of cardiac rhythm regulating devices in adults


2013 Nicole Fowler       ADC       University of Pittsburgh
Abstracts = 2



Trends in Cognitive Decline by Dementia Subtype


Ariel Frankel       Non-ADC       USC
Paper Published
Proposal is complete.



Memory and cognitive function in aging: Can a loss club help?


Tom Fritsch       Non-ADC       Parkison Research Institute
Completed - No Publications
Proposal is complete.



Genetic, clinical and environmental factors and cognitive decline in AD


2014 Ekaterina Galkina       Non-ADC       UMass Lowell
Abstracts = 1



Predicting disease susceptibility using Machine Learning algorithms.


2013 Ekaterina Galkina       Non-ADC       Umass Lowell
Abstracts = 1
Proposal is complete.



Diagnostic Patterns and Healthcare Resource Utilization in Patients with


2014 Joe Gaugler       Non-ADC       UMN
Papers = 1



Empirical Examination of Mismatched In-Vivo and Neuropathological Alzheimer's
Disease Diagnosis


2013 Joesph Gaugler       Non-ADC       School of Nursing, University fo Minnesota
Papers = 1 Abstracts = 1



A Clinical Taxometric Investigation of Alzheimer's Disease and Other Dementias


2012 Brandon Gavett       ADC       Boston
Papers = 1



Cognitive aging trajectories in Alzheimers disease


2014 Brandon Gavett       Non-ADC       University of Colorado at Colorado Springs
Paper Submitted



Robust Norms


Brandon Gavett       ADC       University of Colorado at Colorado Springs
Data File Sent



Neuropathological correlates of mild cognitive impairment


2014 Katherine Gifford       ADC       Boston University
Paper in Prep



Stability and severity of psychiatric symptoms in relation to cognitive,


Katherine Gifford       ADC       Boston University
Paper in Prep



Subjective Memory Complaint and Cognitive Aging


2011 Katherine Gifford       Junior       Vanderbilt
Papers = 2 Abstracts = 2
Proposal is complete.



Handling not-applicable responses in the FAQ


Dawn Gill       NACC       NACC
Completed - No Publications
Proposal is complete.



Rate of functional decline in AD, VaD and DLB


2011 Dawn Gill       NACC       NACC
Papers = 2 Abstracts = 2
Proposal is complete.



Sex differences in rate of progression of three dementia types.


2012 Dawn Gill       NACC       University of Washington - NACC
Abstracts = 1



Stability of Dementia Diagnosis among UDS Participants


2010 Dawn Gill       NACC       University of Washington
Papers = 1 Abstracts = 1



Genetic Architecture of Rate of Decline in Alzheimers Disease


2013 Robert Green       ADC       Brigham Women's Hospital/Harvard Medical School
Abstracts = 3



Are eligible AD clinical trial participants more likely to have spousal
caregivers than adult children caregivers?


2012 Joshua Grill       ADC       UCLA
Papers = 1
Proposal is complete.



Assessing disease progression among Alzheimer's disease patients with adult
child study partners


2014 Joshua Grill       Junior       UCLA
Papers = 1 Abstracts = 1



Choosing Alzheimers disease prevention clinical trial populations.


2014 Joshua Grill       ADC       UCLA
Papers = 1 Abstracts = 1



Examining predictors of AD pathology among cognitively normal UDS participants


Joshua Grill       ADC       UCLA
Data File Requested



Finding combinatorial biomarkers in AD


Vince Grolmusz       Non-ADC       Eotvos University
Completed - No Publications
Proposal is complete.



A reliable, standardized general cognitive performance measure in NACC


2014 Alden Gross       Non-ADC       Hebrew SeniorLife
Abstracts = 1



Long-term course of cognitive and functional decline following delirium in
Alzheimers Disease.


Alden Gross       ADC       Institute for Aging Research, Harvard Medical Sc
Completed - No Publications
Proposal is complete.



A new prediction algorithm for mortality and nursing home admission


Yian Gu       ADC       Columbia University
Data File Sent



Body Mass index Change in Alzheimers Disease Patients


2013 Yian Gu       ADC       Columbia University
Papers = 1 Abstracts = 1



Evaluating sex differences and vascular morbidities in relation to global


2012 Deborah Gustafson       Non-ADC       SUNY Down State Med Center
Abstracts = 1
Proposal is complete.



Atrial Fibrillation in AD Patients


Vladimir Hachinski              London Health Sciences Centre, Western Ontario U.
Data File Sent



The Vascular Component of Behavioral Variant Frontotemporal Dementia


Vladimir Hachinski       Non-ADC       London Health Sciences Centre, Western Ontario U.
Data File Sent



Vascular pathology as a Key Factor for Overall Cognitive Impairment


Vladamir Hachinski       Non-ADC       London Health Sciences Centre, Western Ontario U.
Data File Sent



Antihypertensive effects on neuropathological findings: Analysis of data from


2012 Ihab Hajjar       ADC       University of Southern California
Papers = 1
Proposal is complete.



Latent Class Analysis of MCI Using Longitudinal Clinical Features


2013 John Hanfelt       ADC       Dept. of Biostatistics, Emory University
Abstracts = 1



Latent Structure of the Mild Cognitive Impairment Syndrome


2011 John Hanfelt       ADC       Emory
Papers = 1



Identification of Cognitive Endophenotypes


2009 Kathleen Hayden       Junior       Duke
Papers = 2 Abstracts = 2
Proposal is complete.



Indices of Reliable Change Over Time


2013 Kate Hayden       ADC       DUMC, Bryan ADRC
Abstracts = 1



Rate of progression in Central American and Caribbean Hispanic subjects with
MCI and AD


Kate Heller       NACC       NACC
Data File Sent



The NACC MRI Database


Kate Heller       NACC       NACC
Abstract Accepted



Derving Sensitive Composite Scores


Suzanne Hendrix       Non-ADC       Pentara Corporation
Data File Sent



Cognitive Dispersion in MCI and Dementia Predicting Pathology


Benjamin Hill       Non-ADC       University of South Alabama
Paper in Prep



Type II Diabetes and the risk of cognitive decline: A Multi-Center Cohort Study


2011 Elise Hodges       ADC       University of Michigan Health System
Abstracts = 1



Title: Genetic Resilience to Alzheimer's Related Neuropathology and Cognitive
Decline


Timothy Hohman       Non-ADC       Vanderbilt University Medical Center
Data File Sent



Atherosclerosis and AD: analysis of data from the US National Alzheimer's
Coordinating Center


2005 Larry Honig       ADC       Columbia University
Papers = 1
Proposal is complete.



Prediction of Progression in Early Alzheimer Disease


Daniel Horton       Non-ADC       University of Texas Southwestern Medical Center
Data File Sent



A Correlation Study for the Relationship between Neuropsychiatric Symptoms and
Alzheimer's Disease.


Tianyan Hu       Non-ADC       University of Pennsylvania
Data File Sent



A Longitudinal Scale for Disease Progression in Frontotemporal Lobar
Degenerations


William Hu       ADC       Emory University
Data File Sent



Analyses of Prognostic Accuracy of Markers in NACC Study


Nan Hu       NACC       NACC
Completed - No Publications
Proposal is complete.



Evaluation of Neuropsychological Biomarkers for Classifying Stages
of Alzheimers Disease


Nan Hu       Non-ADC       University of Utah
Completed - No Publications
Proposal is complete.



Classification on disease status transition using transfer learning algorithm


Wen-Yu Hua       Non-ADC       Department of Statistics The Penn State University
Data File Sent



Non-homogeneous Markov process models for rate of conversion to MCI


2011 Rebecca Hubbard       NACC       NACC
Papers = 3 Abstracts = 4
Proposal is complete.



Health Disparities in Risks for Cognitive Decline


Travonia Hughes       Non-ADC       Johns Hopkins Bloomberg School of Public Health
Data File Sent



Agreement Between Informant and Physician Rating of Apathy in AD.


Kim Hutchinson       Non-ADC       Fielding Graduate University
Data File Sent



Risk Factors for Apathy in AD


Kim Hutchinson       Non-ADC       Fielding Graduate University
Paper Submitted



Clinical -Pathological investigation regarding new criteria for


2013 Brad Hyman       ADC       Mass General
Papers = 4



Evaluation of inclusion exclusion criteria in clinical trial design


2008 Bradley T. Hyman       ADC       Mass ADRC
Abstracts = 1
Proposal is complete.



Neuropathological correlates of patients with impaired, not MCI cognitive


Brad Hyman       ADC       Massachusetts Alzheimer Disease Research Center
Data File Sent



Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Evaluate the


Bruno Imbimbo       Non-ADC       Chiesi Farmaceutici
Data File Sent



Cognition and Imaging in Neurodegenerative Disease


Philip Insel       ADC       UCSF
Completed - No Publications
Proposal is complete.



Examine the incidence of delusions and hallucinations in AD and their impact on


Farzin Irani       ADC       U Penn
Completed - No Publications
Proposal is complete.



The prevalence of amyloid pathology in non-demented subjects: a meta-analysis


Willemijn Jansen       Non-ADC       Maastricht University
Data File Sent



Project validating the use of the CDR Sum of Boxes as a single primary efficacy


Mark Jaros       Non-ADC       Elan Corporation
Completed - No Publications
Proposal is complete.



MCI, Neuropsychiatric Symptoms, and Functional Impairment


Angela Jefferson       ADC       Vanderbilt (prev Boston University)
Completed - No Publications
Proposal is complete.



Politico-economic, Ethnic, and Regional Personality Differences


Mark Jefferson       Non-ADC       Walden University
Paper in Prep



Vascular risk factors of cognitive aging


2012 Angela Jefferson       ADC       Boston University
Abstracts = 1



Confirmatory Factor Analyses Using Neuropsychiatric Inventory Data
from the National Alzheimer's Coordinating Center


2011 David Johnson       Non-ADC       University of Kansas
Papers = 1
Proposal is complete.



Clinicopathologic correlation in FTLD


2013 Aditi Joshi       ADC       UCLA
Papers = 2 Abstracts = 2



Trajectory of Dementia


Eric Jutkowitz       Non-ADC       University of Minnesota
Data File Sent



APOE and Relationship to Abstinence from Cigarette Smoking among Older Adults
with Normal Cognition


2013 Rajkumar Kalapatapu       ADC       UCSF
Papers = 1



Characterizing Substance Use History in Frontotemporal Dementia


Raj Kalapatapu       ADC       UCSF
Not Started



Rate of Decline: Smokers and Nonsmokers


Raj K. Kalapatapu       ADC       Mount Sinai
Completed - No Publications
Proposal is complete.



continuation of project on the role of substance abuse on neurocognitive


Raj Kalapatapu       ADC       Columbia University/NY State Psychiatric Institu
Completed - No Publications
Proposal is complete.



The influence of smoking history on the phenotype and pathology of dementia


2012 Berneet Kaur       Junior       UC Davis
Abstracts = 2



United Parkinson's Disease Rating Scale (UPDRS) Data Analyses


2013 Berneet Kaur       ADC       UC Davis
Papers = 1 Abstracts = 2



Establishing AD risk profiles based on early cognitive changes in normal
controls


Stephanie Kielb       ADC       Northwestern Feinberg School of Medicine
Data File Sent



Establishing preclinical cognitive and risk profiles associated with the
development of Alzheimer's disease


Stephanie Kielb       ADC       Northwestern University CNADC
Data File Sent



Statistical Method for combining multiple biomarkers


Eunhee Kim       Non-ADC       Brown University
Data File Sent



Evaluation of FTLD module data


Dave Knopman       ADC       
Data File Sent



The utility of a language domain rating and a behavior-comportment and


2011 David Knopman       ADC       Mayo Clinic
Papers = 1 Abstracts = 2



Characterizing UDS Participants who Revert from MCI to Normal Cognition


2011 Tom Koepsell       NACC       University of Washington
Papers = 1 Abstracts = 1
Proposal is complete.



Education, cognitive function, and severity of neuropathology in AD


2008 Tom Koepsell       NACC       
Papers = 1 Abstracts = 1
Proposal is complete.



Mathematical modeling of epidemiology of Alzheimer's disease.


Natalia Komarova       ADC       University of California Irvine
Data File Sent



Quantifying variability in individual specific trajectories between NACC


Jennifer Koontz       ADC       UC Irvine
Paper in Prep



Neuropsychological, Motor, and Pathological Evaluation of the Primary


2013 Sarah Kremen       ADC       UCLA
Abstracts = 1



Comparison of motor symptoms in MCI by underlying disease process


2013 Walter Kukull       NACC       NACC
Abstracts = 1



Lewy body pathology and clinical diagnoses in the NACC database


2006 Walter Kukull       NACC       NACC
Abstracts = 1
Proposal is complete.



Primary Neuropathologic Diagnosis and Co-Occurrence of Other Neuropathologic
Features: Results from the NACC database


2009 Walter Kukull       NACC       NACC
Abstracts = 1
Proposal is complete.



Standardized data collection and diagnostic formulation for FTLD Clinical Exam:


2012 Walter Kukull       NACC       NACC
Abstracts = 1
Proposal is complete.



Utility of the Clinical Dementia Rating Scale Sum of Boxes Scores in Staging
Dementia Severity


2010 Laura Lacritz       Non-ADC       University of Texas Southwestern Medical Center
Papers = 1
Proposal is complete.



Relation of Diabetes Medications to Cognitive and Neuropathological Findings in


2013 Elizabeth Lane       Non-ADC       Vanderbilt University Medical School
Abstracts = 1



Inappropriate Drug Use among Community-Dwelling Elders with Dementia


2008 Denys Lau       ADC       University of Illinois at Chicago
Papers = 2 Abstracts = 3
Proposal is complete.



Nighttime Behaviors and Cognitive Decline


Hiuyan Lau       ADC       NYU Langone Medical Center, ADC
Data File Sent



Age-associated Memory Impairment as a predictor of future cognitive decline


2012 Grace Lee       ADC       UCLA
Abstracts = 1



Modeling disease progression in AD with monotone dropouts


Catherine Lee       Non-ADC       Harvard School of Public Health - Biostatistics
Data File Sent



Pathological-Behavioral correlations in FTD spectrum disorders


2014 Gabriel Leger       Non-ADC       Cleveland Clinic Lou Ruvo Center for Brain Healt
Papers = 1 Abstracts = 1



Latent Classes of Cognitive and Functional Trajectories in AD


Jeannie-Marie Leoutsakos       Non-ADC       Johns Hopkins School of Medicine
Data File Sent



Mild behavioral impairment (MBI) in normal aging and MCI


Jeannie-Marie Leoutsakos       Non-ADC       Johns Hopkins School of Medicine
Paper Published



Neuropsychiatric Syndromes in Dementia: Evolution, Risk Factors and Outcomes


Jeannie Leoutsakos       ADC       Johns Hopkins University School of Medicine
Data File Sent



Tree-Based Classification of AD Risk Using KappaTree


Jeannie-Marie Leoutsakos       Non-ADC       Johns Hopkins School of Medicine
Data File Sent



Distribution and Correlation of AD survival andprogression rates with
Neuropathology


2014 Alan Lerner       Non-ADC       Case Western Reserve University
Paper Submitted



Factors Associated with Use of Memantine


2009 Alan Lerner       ADC       Case Western
Papers = 2
Proposal is complete.



NPI-Q scores across different study populations


Fanny Leung       ADC       University of Pennsylvania
Data File Sent



Covariate adjustment in estimating the area under the ROC curve with partially


2013 Danping Liu       NACC       NACC
Papers = 2



Estimating the standardized ROC curve adjusting for covariate effects with


2013 Danping Liu       NACC       University of Washington
Papers = 1



Longitudinal analysis of cognitive decline in amnestic MCI subjects using
multiple imputation


Danping Liu       Non-ADC       NIH
Data File Sent



Sequential Biomarker Evaluation and Risk Prediction for Alzheimer Disease


Dandan Liu              Vanderbilt University
Data File Sent



Differential item response in the USC ADRC measure of neuropsychological


Donald Lloyd       ADC       USC
Completed - No Publications
Proposal is complete.



Ethnicity difference in comorbidity of depression and dementia


Donald Lloyd       ADC       USC
Completed - No Publications
Proposal is complete.



Measurement equivalence of the ADRC neuropsychological test battery across


Donald Lloyd       ADC       USC
Completed - No Publications
Proposal is complete.



Measurement invariance in the geriatric depression scale by dementia status,


Donald Lloyd       ADC       USC
Completed - No Publications
Proposal is complete.



Physical health and neuropsychological test performance in the USC ADRC


Donald Lloyd       ADC       USC
Completed - No Publications
Proposal is complete.



Sociodemographic patterns in the progression from normal cognitive status to


Donald Lloyd       ADC       USC
Completed - No Publications
Proposal is complete.



Risk of Self-Reported Head Injury in the Development of Mild Cognitive
Impairment and Alzheimer's Disease


Christian LoBue       ADC       UT Southwestern Medical Center
Data File Sent



Analysis of Gene-Environment Interactions in Alzheimer's Disease


Iryna Lobach       ADC       UCSF
Data File Sent




Associations between microinfarcts and other macroscopic vascular findings on


2009 Will Longstreth       Non-ADC       University of Washington
Papers = 1
Proposal is complete.



Depression and Insight


2008 Po H. Lu       ADC       U California, Los Angeles
Abstracts = 1
Proposal is complete.



Data to support the NIH funded study Perioperative Cognitive Protection


Xiaodong Luo       ADC       Mt Sinai ADRC
Completed - No Publications
Proposal is complete.



Normative data for the neuropsychological assessment from the Alzheimers


2013 Xiaodong Luo       ADC       Mount Sinai
Papers = 1 Abstracts = 1



Clinically Unrecognized Cases of Prion Disease in the National Alzheimer's


2008 Ryan Maddox       Non-ADC       CDC
Abstracts = 1



Associations of Genotype and Haplotype Data with Cognitive Decline


Jonathan Mahnken       ADC       The University of Kansas Medical Center
Data File Sent



FAQ: Analysis


Janice Marceaux       ADC       University of Alabama at Birmingham (UAB)
Paper in Prep



The role of race and socio-economic status in the cognitive decline of black
older adults.


Karyn Marsh       ADC       New York University School of Medicine
Completed - No Publications
Proposal is complete.



Cognitive and Functional Profiles of Mild Cognitive Impairment
in African-American and Caucasian Samples


Dan Marson       ADC       National Alzheimer's Coordinating Center
Paper in Prep



The Epidemiology of Alzheimers disease in Washington State


2013 Christine Mayambala-Ivy       Non-ADC       Walden University
Abstract Submitted



Determinants of Judgment and Problem Solving


2009 Ann Mayo       ADC       University of California, San Francisco
Papers = 1 Abstracts = 1
Proposal is complete.



Cost of Alzheimer's Disease


Nicola McCarthy       Non-ADC       Stevens Institute of Technology
Data File Sent



Ethnic Differences in Alzheimer's Disease Survival and Pathology


2009 Kala Mehta       Junior       UC San Francisco
Papers = 2 Abstracts = 2
Proposal is complete.



Antithrombotic medication use and dementia incidence among mild cognitive
impairment patients with atrial fibrillation


2013 Dana Meranus       NACC       NACC
Abstracts = 1



Cholinesterase Inhibitors and Memantine Use in the National


2012 Dana Meranus       NACC       NACC
Abstracts = 1
Proposal is complete.



Describing controls in the National Alzheimer's Coordinating Center Database


Dana Meranus       NACC       NACC
Completed - No Publications
Proposal is complete.



A liability model to increase power in genome-wide association


Jesse Mez       ADC       Boston University Alzheimer's Disease Center
Data File Sent



Dysexecutive function in Alzheimer's Disease: A genetic and neuropsychologic


2013 Jesse Mez       ADC       Columbia University
Papers = 1 Abstracts = 1



Heritability for dysexecutive function


Jesse Mez       ADC       Boston University
Data File Sent



Longitudinal evaluation of dysexecutive vs. amnestic Alzheimer's


2013 Jesse Mez       ADC       Columbia
Papers = 2 Abstracts = 1



The relationship between neuropathology and expression of dementia in the


2010 Laura Middleton       Non-ADC       Univ Waterloo
Papers = 1 Abstracts = 1
Proposal is complete.



Pre-clinical AD Susceptibility Based on CSF Biomarkers and Cognition


Steve Millard       Non-ADC       VA Puget Sound
Data File Sent



Development and Stability of Delusions Across the Spectrum from Normal Aging to


2014 Colleen Millikin       Non-ADC       University of Manitoba
Abstracts = 1



Frequency of Frontal Hypometabolism in Autopsy Confirmed AD Subjects


Lindsey Minshew       Non-ADC       University of Utah
Data File Sent



Identifying functional milestones in disease progression in frontotemporal
dementia


Eneida Mioshi       Non-ADC       Neuroscience Research Australia
Data File Sent



Risk factors for MCI: Traumatic brain injury and depression


Effie Mitsis       ADC       Mt Sinai
Abstract Accepted



: Comparison of symptomatic and asymptomatic persons with underlying Alzheimers


2013 Charlie Mock       NACC       
Papers = 1



Genetic differences between symptomatic and asymptomatic persons with AD
neuropathologic change


Charlie Mock       NACC       NACC
Data File Sent



Trends in performance on neuropsychological tests for asymptomatic persons with


2014 Charlie Mock       NACC       NACC
Paper Submitted



Analysis of Smoking and Vascular Risk Factor Impact on Progression from Mild


Stephen Moelter       Non-ADC       University of the Sciences in Philadelphia
Paper in Prep



Evaluating the magnitude of potentially inappropriate medication prescribing
and its impact on mortality in the NACC cohort


Daniela Moga       ADC       University of Kentucky
Data File Sent



Evaluation of use and risks associated with bladder antimuscarinics


2014 Daniela Moga       Non-ADC       University of Kentucky
Abstract Submitted



APOE e4 and clinical progression in Parkinson's disease


2013 Sarah Monsell       NACC       NACC
Papers = 1 Abstracts = 1



Clinical presentation and co-pathologies in neuropathologic Lewy Body disease


Sarah Monsell       NACC       NACC
Data File Sent



Development of a weighted composite score for measuring cognitive decline


Sarah Monsell       NACC       NACC
11



Differences in clinical presentation among early-onset and late-onset
parkinsons disease patients.


Sarah Monsell       NACC       University of Washington, NACC
Completed - No Publications
Proposal is complete.



Hearing impairment and cognitive decline in the UDS


Sarah Monsell       NACC       NAA
Completed - No Publications
Proposal is complete.



Variation among different measurements of cognitive decline


2011 Sarah Monsell       NACC       NACC
Papers = 1 Abstracts = 1
Proposal is complete.



Clinical accuracy of the etiologic diagnosis in MCI


John Morris       ADC       Washington University in St. Louis
Data File Requested



Diabetes and preclinical AD


Jill Morris       ADC       KU Medical Center
Data File Sent



Influence of seizures and seizure medications on course of AD dementia


John Morris       ADC       Washington University
Data File Sent



Outcomes of individuals diagnosed with Alzheimer disease dementia by a single


John Morris       ADC       Washington University
Data File Sent



The Uniform Data Set (UDS): Clinical and Cognitive Variables and Descriptive


2006 John Morris       ADC       Washington University School of Medicine
Papers = 1 Abstracts = 1
Proposal is complete.



Alzheimer's and Vascular Neuropathological Substrates of Empirically-Derived
Subtypes


Daniel Nation       ADC       University of Southern California
Data File Sent



Basic clinical-pathological correlation in AD


2011 Peter Nelson       ADC       University of Kentucky
Papers = 3



Braak Staging over Time: A Possible Cohort Effect


2009 Peter T. Nelson       ADC       University of Kentucky
Papers = 2
Proposal is complete.



Clinicopathological correlation in Dementia with Lewy bodies (DLB)


2010 Peter Nelson       ADC       Kentucky
Papers = 4



Evaluating genetic risk factors of hippocampal sclerosis (HS) in FTLD


Pete Nelson       ADC       U Kentucky
Data File Sent



Evaluation of association between sulfonylurea use and hippocampal sclerosis
pathology


2014 Pete Nelson       ADC       U Kentucky
In Press



Hippocampal sclerosis of aging in NACC


2014 Peter Nelson       ADC       U Kentucky
Papers = 2 Abstracts = 1



Operationalization of Hypertension and Diabetes in the Aged Population Using
NACC Database


Pete Nelson       ADC       U Kentucky
Data File Requested



Using biomarkers to predict the progression of Alzheimers disease


Imola Nemeth       Non-ADC       University of Manchester
Paper in Prep



Strategies to reduce site differences in multisite studies: a case study of
Alzheimer disease progression


Art Noda       ADC       Stanford
Abstract Published
Proposal is complete.



Diagnostic Accuracy of the MMSE in Detecting Dementia in Ethnically Diverse
Highly Educated Individuals


2012 Sid E. O'Bryant       Non-ADC       
Papers = 1



Effects of 100 commonly used drugs on cognitive performance in older adults.


2013 Karen Obermann       Non-ADC       St. Louis College of Pharmacy
Papers = 1



Estimating the Cost of Delayed Treatment for Alzheimers Disease


2012 Natalia Olchanski       ADC       Tufts Medical Center
Abstracts = 1
Proposal is complete.



Cognitive Reserve and Executive Cognition in Frontotemporal Dementia


2010 Chiadi Onyike       ADC       Johns Hopkins
Abstracts = 1



Prevalence of amyloid pathology in demented patients


Rik Ossenkoppele       Non-ADC       VU University Medical Center
Data File Sent



Clinical Characterization and Outcome of Subjects with Mild Cognitive


2010 Ronald Petersen       ADC       Mayo Clinic Rochester
Abstracts = 1



Description of UDS MCI, pre-MCI, and Control Subjects


2010 Ronald Petersen       ADC       Mayo
Abstracts = 1
Proposal is complete.



MCI and its subtypes by etiology


Ronald Petersen       ADC       Mayo Clinic
Completed - No Publications
Proposal is complete.



Baseline study factors the predict dropout in the UDS


2009 Leslie E. Phillips       NACC       NACC
Abstracts = 1
Proposal is complete.



Demographic, Clinical and Genetic Characteristics of symptomatic and


2010 Leslie Phillips       NACC       U of Washington
Abstracts = 1
Proposal is complete.



Normal subject description


Leslie Phillips       NACC       
Completed - No Publications
Proposal is complete.



The role of cognitive reserve in neuropathological FTD


2011 Leslie Phillips       NACC       NACC - Universtiy of Washington
Abstracts = 1
Proposal is complete.



Neuropsychological predictors of dementia progression trajectory


2013 Jagan Pillai       Non-ADC       Cleveland Clinic
Paper Submitted



Variability in clinical trajectory within AD, FTD, LBD, VD, HSD, CJD and mixed
dementia diagnostic categories.


Jagan Pillai       Non-ADC       Cleveland Clinic
Data File Sent



Non-replication of an association of Apolipoprotein E2 with sinistrality


2013 Brian Piper       Non-ADC       Oregon Health Science University
Papers = 1
Proposal is complete.



ACE Inhibitor, Angiotensin II Receptor Blockers, and ApoE4 on Alzheimer's


2013 Wendy Qiu       ADC       Boston University
Abstracts = 1



Angiotensin Converting Enzyme Inhibitor and ApoE4 on Alzheimers disease


2014 Wendy Wei Qiao Qiu       ADC       Boston University School of Medicine
Papers = 1



Therapeutic target finding of Alzheimers disease via identification of GWAS
analysis related susceptible genes and signaling pathways, and meta-analysis of


Yu Qiu       Non-ADC       Shanghai Jiao Tong University School of Medicine
Data File Sent



Pathology of subjects clinically diagnosed with vascular dementia


2005 EM Ramos       Non-ADC       University of Washington
Abstracts = 1
Proposal is complete.



Neuropathological Changes in Dementia in Patients with Co-morbid Depression


2008 Michael Rapp       Junior       Mt Sinai
Papers = 1 Abstracts = 1
Proposal is complete.



Neuropathological assessments of fibrillar amyloid burden in APOE e4 carriers
and non-carriers with the clinical diagnosis of Alzheimer's dementia


2014 Eric Reiman       ADC       Banner Alzheimer's Inst
Abstract Submitted



Clinical and Cognitive Predictors of Severe Cerebral Amyloid Angiopathy


2011 John Ringman       ADC       UCLA
Papers = 1 Abstracts = 2



Effects of antiepileptic drugs on AD progression


Erik Roberson       ADC       University of Alabama at Birmingham
Completed - No Publications
Proposal is complete.



CSF Biomarkers of AD: Cognitive and Non-Cognitive Outcomes


Cathy Roe       ADC       Washington University School of Medicine
Data File Sent



Education, The Cognitive Reserve Hypothesis, and Alzheimer's Disease Without
Dementia


2006 Cathy Roe       Junior       Wash U
Papers = 3 Abstracts = 3
Proposal is complete.



Effect of Medications on Cognition


Catherine Roe       ADC       Washington University School of Medicine
Data File Requested



Level of functional and cognitive impairment as a function of DAT severity


2012 Catherine Roe       ADC       Washington University School of Medicine
Papers = 1
Proposal is complete.



Examining the Relationship between Traumatic Brain Injury and the Onset of
Schizophrenia-Like Symptoms


Denise Romanow       Non-ADC       Illinois School for Professional Psychology
Data File Sent



Diagnostic Stability of Transitional States in a Diverse Population


Heather Romero       Junior       Duke
Data File Sent



Sex-specific patterns and differences in the core modalities associated with
Alzheimer's disease


2014 Jeremiah Ronqiullo       Non-ADC       Geronimo Ronquillo LLC
Paper Submitted



Affective symptoms and vascular factors are more prevalent in non-amnestic
than amnestic Mild Cognitive Impairment (MCI)


2011 Paul Rosenberg       ADC       Johns Hopkins
Papers = 1 Abstracts = 1
Proposal is complete.



Neuropathological correlates of apathy in Alzheimer???s Disease


2013 Paul Rosenberg       ADC       Johns Hopkins University School of Medicine
Paper Submitted



THE ASSOCIATION OF PSYCHOTROPIC MEDICATIONS WITH THE COGNITIVE AND FUNCTIONAL
TRAJECTORY OF MCI AND ALZHEIMERS DISEASE


2013 Paul Rosenberg       ADC       John Hopkins
Paper Submitted



The association of neuropsychiatric symptoms in MCI with incident dementia and
Alzheimers Disease.


2013 Paul Rosenberg       ADC       John Hopkins
Papers = 1
Proposal is complete.



Are there major pathological differences between amnestic and nonamnestic mild
cognitive impairment?


Marwan Sabbagh       ADC       Banner Sun Health Research Institute
Data File Sent



Assessing the effect of race and education on the


2013 Michael Sachs       NACC       NACC, University of Washington
Papers = 1



Factors associated with performance of autopsy among decedents in the UDS


Michael Sachs       ADC       University of Washington - Department of Biostatis
Completed - No Publications
Proposal is complete.



Verification Bias


2008 Michael Sachs       NACC       previous NACC investigator
Abstracts = 2
Proposal is complete.



EXPLORING MULTIDIMENSIONAL COMPLEXITY IN THE DEMENTIAS: THE ASSOCIATION OF


2014 Tatiana Sadak       Non-ADC       UW
Papers = 1 Abstracts = 4



APOE Genotype Distribution in Non-Genetically Determined Early-Onset
Alzheimer's Disease


David Salmon       ADC       UCSD
Data File Sent



Diabetes and Alzheimers Disease in the Uniform Data Set


2012 Mary Sano       ADC       Mount Sinai
Papers = 1



Cross-cultural Differences in the Diagnosis of Dementia


2013 Philip Sayegh       ADC       3620 S. McClintock Ave., SGM 501
Papers = 2 Abstracts = 4



Jointly modeling transition rates of multi-state cognitive outcomes with random


Elizabeth Schofield       ADC       Byrd Alzheimer's Institute
Completed - No Publications
Proposal is complete.



International Neuropsychological Normative Database Initiative


David Schretlen       ADC       Johns Hopkins University
Data File Sent



APOE e4 allele and genotype frequencies of normal controls


Erick Scott       Non-ADC       Scripps Translational Science Institute/ TSRI
Data File Sent



Motor functioning in mild cognitive impairment


Daniel Seichepine       ADC       Boston U
Completed - No Publications
Proposal is complete.



Clinicopathologic correlation: Alzheimer mimics


2011 Yong Soo Shim       ADC       Washington U
Papers = 1 Abstracts = 1



Normative Calculator for the Uniform Data Set (UDS) Neuropsychological Test


2011 Steven Shirk       ADC       Edith Nourse Rogers Memorial Veterans Hospital
Papers = 1



The role of seizures in dementia: risk factors and effects on clinical course


Steven Shirk       ADC       Edith Nourse Rogers Memorial Veterans Hospital
Data File Sent



Biracial differences in the relation between systemic vascular health and
neuropathological markers of cerebrovascular and Alzheimer's disease


Jeannine Skinner       Non-ADC       Vanderbilt Memory and Alzheimer Center
Data File Sent



Cross-sectional and longitudinal relations between cardiovascular health and
cognitive function in minority elders


2014 Jeannine Skinner       Non-ADC       Vanderbilt University Medical Center
Abstract Submitted



Genetic variability and cardiovascular disease (CVD) burden as predictors of
cognition in African American elders


2014 Jeannine Skinner       Non-ADC       Vanderbilt University Medical Center
Abstract Submitted



Association of Cognitive Impairment and Depression


2014 Mark Snowden       Non-ADC       University of Washington
Paper Submitted



Correlation between androgen deprivation therapy and cognitive function


Sophie Sokolow       ADC       UCLA School of Nursing
Completed - No Publications
Proposal is complete.



Mild Cognitive Impairment in Parkinson's disease: Cognitive, Motor, and
Behavioral Characterization


Ann Sollinger       ADC       
Completed - No Publications
Proposal is complete.



Modeling and computer simulation studies of cognitive decline progression and


2013 Carlos Soto-Campos       Non-ADC       Ciudad Universitaria de la UAEH
Papers = 1



Dependence as a health outcome for Alzheimer's disease


2013 Eldon Spackman       ADC       University of Washington - School of Pharmacy
Papers = 1



Transitions and pharmaceutical use by CDR level in Alzheimers disease.


2012 Eldon Spackman       Non-ADC       University of Washington
Papers = 2 Abstracts = 1



The Placebo Group Simulation Approach (PGSA): Predicting Decline in Patients


2011 Rene Spiegel       Non-ADC       Memory Clinic, Geriatric University Hospital
Abstracts = 3



Vascular and behavioral symptoms predict progression from healthy aging to
dementia


2014 Drake Steed       Non-ADC       Illinois School for Professional Psychology at Arg
Abstracts = 1



Cognitive decline and neuropathology in relation to air pollution


Kyle Steenland       ADC       Emory
Completed - No Publications
Proposal is complete.



Hypertension and the effect of hypertension on cognitive decline using NACC UDS


2013 Kyle Steenland       ADC       Emory
Papers = 1



Noradrenergic Medications and Progression of MCI


2012 Kyle Steenland       ADC       Emory
Papers = 1
Proposal is complete.



Proposal to Use UDS/NACC Data to Further Study Depression and Progression to


2011 Kyle Steenland       ADC       Emory
Abstracts = 1
Proposal is complete.



Statins and cognitive changes over time


2013 Kyle Steenland       ADC       Emory
Papers = 1



The effect of anti-hypertensive medication acting on the rennin-angiotensin
system on cognitive function


Kyle Steenland       ADC       Emory
Data File Sent



Variations across Centers


2010 Kyle Steenland       ADC       Emory
Papers = 1 Abstracts = 1
Proposal is complete.



Diagnostic Accuracy of a Binary Test in the Presence of Two Types of Missing


Jeffrey Stratton       Non-ADC       University of Connecticut
Paper Published



Clinical and pathological characteristics of hippocampal sclerosis dementia


2013 Campbell Sullivan       ADC       Johns Hopkins University, School of Medicine
Abstracts = 1



Anticholinergic Drug Use And Risk Of Cognitive Decline And Dementia Among Older


Sunil Swami       Non-ADC       University of Florida
Data File Sent



Correlates of Psychosis in AD


2011 Robert Sweet       ADC       University of Pittsburgh
Papers = 1
Proposal is complete.



Examining the Association between Neuropsychiatric Symptoms, Hypertension,
Hypercholesterolemia, and Diabetes in Alzheimer's disease


2014 Carmela Tartaglia       Non-ADC       U Toronto
Abstract Accepted



Determining specific functional declines associated with progression from mild


2012 Edmond Teng       ADC       UCLA/Greater Los Angeles VA Healthcare System
Papers = 1 Abstracts = 1



Investigating the Role of Traumatic Brain Injury as a Risk Factor for
Frontotemporal Lobar Degeneration


2013 Edmond Teng       ADC       West Los Angeles VA/UCLA
Abstract Accepted



The Alzheimers Disease Centers Uniform Data Set(UDS):Using various algorithms
to predict Dementia types with MMSE and CDR


2013 Ya Lun Teng       Non-ADC       Tatung University
Abstract Submitted



Utility of the Functional Activities Questionnaire in Distinguishing Between
Mild Cognitive Impairment and Mild Alzheimer's Disease


2010 Edmond Teng       ADC       University California, Los Angeles
Papers = 2 Abstracts = 2
Proposal is complete.



Data mining of large sample Alzheimer's disease for early warning and diagnosis


yuanxiang Tian       Non-ADC       China Academy of Chinese Medical Sciences
Data File Sent



Neuropathology of Depression in MCI and Early AD


Sarah Tighe       Non-ADC       University of Iowa
Data File Sent



Clinical Role of Vitamin B12 in Pathological Confirmed AD Patients


Simon Kang Seng Ting       Non-ADC       Singapore General Hospital
Data File Sent



Clinicopathological correlation of psychosis and brain vascular burden in
Alzheimer's disease


Simon Kang Seng Ting       Non-ADC       Department of Neurology, Singapore General Hospita
Abstract Submitted



Analysis of disease duration and disease duration modifiers in the NACC
neuropathology database


Jon Toledo       ADC       CNDR, UPenn School of Medicine
Data File Sent



Cerebrovascular changes and prevalence of vascular risk factors across
different neurodegenerative diseases


2013 Jon Toledo       ADC       CNDR, UPenn School of Medicine
Papers = 1



Effect of mixed neuropathologies on profile and cognitive change in dementia


2013 Jon Toledo       ADC       CNDR, UPenn School of Medicine
Abstracts = 1



Analysis of genetic susceptibility loci underlying Alzheimer's disease with
additional feature


2014 Giuseppe Tosto       ADC       Columbia
Paper Submitted



Rapidly progressive dementia


Giuseppe Tosto       ADC       Columbia
Data File Sent



Progression and Conversion in African American and Caucasian Patients
with Mild Cognitive Impairment


Kirsten Triebel       ADC       University of Alabama at Birmingham
Paper in Prep



Specifically, we propose to apply a longitudinal factor analysis model to a
variety of neuropsychological tests and estimate a smooth cognitive trajectory.


Yorghos Tripodis       Junior       Boston University
Data File Sent



Comparison of Agitation and Aggression Across Dementias: Relationship to


2013 Paula Trzepacz       Non-ADC       Eli Lilly and Company
Papers = 1
Proposal is complete.



Prevalence of Seizures, Tremor and Gait Disturbances in AD


2013 Paula Trzepacz       Non-ADC       Eli Lilly and Company
Abstracts = 1



Relationship of Agitation and Aggression in Alzheimers disease (AD) and MCI


Paula Trzepacz       Non-ADC       Eli Lilly and Company
Completed - No Publications
Proposal is complete.



Association between TAU haplotypes and head injury in probable AD cases -
Replication Sample Request


Debby Tsuang       Non-ADC       UW / GRECC
Data File Requested



Male/Female Differences in the Pathogenesis and Presentation of Alzheimer's
Disease in Pre-symptomatic, Early Symptomatic and Late Stages.


Adaugo Ugocha       Non-ADC       Amherst College
Data File Sent



Role of Vascular Risk factors on progression of cognitive impairment in AD


2013 Anand Visnawathan       ADC       Mass ADRC
Paper Submitted



Traumatic Brain Injury as a Factor in Development, Age of Onset, and Course of
Progression in Alzheimer's Disease


Vanessa Vudy       Non-ADC       University of Colorado Colorado Springs
Data File Sent



Latent Structure of Alzheimer's Disease: A Taxometric Analysis of
Neuropsychological Indicators


2010 Glenn Walters       Non-ADC       
Papers = 1
Proposal is complete.



The association between statin use and dementia in Alzheimer's Disease


Meena Wanas       Non-ADC       Campbell University
Completed - No Publications
Proposal is complete.



Alcohol abuse and cognitive decline in men and women


Yixin Wang       NACC       NACC
Data File Requested



Causal inference with truncation by death in observational study


2013 Linbo Wang       NACC       University of Washington
Abstracts = 1



Evaluate Diagnostic Accuracy in the Absence of a Gold Standard


2013 Zheyu Wang       Non-ADC       University of Washington
Abstracts = 1



Non-parametric and semi-parametric estimation of quantile residual lifetime for


Yixin Wang       NACC       NACC
Data File Sent



Quantile Regression to Detect Subtle Cognitive Decline


Lan Wang       Non-ADC       University of Minnesota
Data File Requested



Quantile regression analysis with missing data with applications to analysis of


Lan Wang       Non-ADC       University of Minnesota
Completed - No Publications
Proposal is complete.



Semi-parametric model for interval censored data with a cured subgroup


2013 Linbo Wang       NACC       NACC
Abstracts = 1



To evaluate the association between time to dementia and baseline risk factors


Lu Wang       ADC       Michigan
Completed - No Publications
Proposal is complete.



Age at onset, education and MMSE in Native Americans


2007 Myron Weiner       ADC       Univ of Texas SW Med Ctr
Papers = 1
Proposal is complete.



Describe score distributions for Normal, MCI, and specific dementia diagnoses.


2009 Sandra Weintraub       ADC       Northwestern
Papers = 1
Proposal is complete.



Early Detection of Cognitive Impairment: NIH Toolbox Cognitive Function Battery


Kathleen Welsh-Bohmer       ADC       Duke
Completed - No Publications
Proposal is complete.



Neuropsychological data mining to understand the sensitivity of various
cognitive measures in early AD


Alette Wessels       Non-ADC       Eli Lilly Company
Data File Sent



Biomarkers of Inflammation and Renal Insufficiency in Aged Cognitively Impaired


Jeanna Winchester       ADC       University of California at Irvine
Completed - No Publications
Proposal is complete.



Autosomal recessive causes of early onset Alzheimer???s disease


Thomas Wingo       ADC       Emory University
Data File Requested



Estimate the heritability of AD using family history data


2012 Thomas Wingo       ADC       Emory Center for Neurodegenerative Disease
Papers = 1
Proposal is complete.



Does loss of a spouse impact cognitive trajectory in normal controls, MCI and


2014 Laura Wojtulewicz       Non-ADC       Arizona State University
Abstract Submitted



Investigating Alzheimer's Disease using Data Mining
Techniques


Laura Wojtulewicz       Non-ADC       Arizona State University
Completed - No Publications
Proposal is complete.



Logical memory delayed recall, men vs. women


Laura Wojtulewicz              Arizona State University
Data File Sent



Rapcsak Sensitivity of Different Language Measures


Laura Wojtulewicz       Non-ADC       Arizona State University
Data File Sent



Effects of angiotensin receptor blockers and ACE inhibitors on dementia


Benjamin Wolozin       ADC       Boston University School of Medicine
Completed - No Publications
Proposal is complete.



Characterizing MCI subjects who remained cognitively stable


Martin Woon       ADC       UTSW
Abstract Submitted



Predicting trajectories of MCI with medical, demographic, genetic, and
neuropsychological data


2014 Martin Woon       ADC       UT Southwestern Medical Center
Abstract Submitted



Ensemble based Data classification for Early Diagnose of Alzheimer


Henok Wordoffa       Non-ADC       Blekinge Institution of Technology
Paper Published



Clinical utility of the Clinical Dementia Rating Scale for Parkinson's
disease dementia


Kathryn Wyman-Chick       Non-ADC       Pacific University SPP (doctoral student)
Paper Published



Antedependence Models for Nonstationary Categorical Longitudinal Data with
Ignorable Missingness: Likelihood-Based Inference


2013 Yunlong Xie       Non-ADC       National Institutes of Health
Papers = 1



Use of UDS to improve clinical trial design on MCI and preclinical AD


Chengjie Xiong       ADC       Washington University
Data File Sent



Longitudinal trajectory of neuropsychological performance and dementia subtypes


Huiping Xu       ADC       Indiana University
Paper in Prep



The Combined Influence of Vascular Risk Factors and Alzheimers Disease on
Cognition, and the Role of Vascular Neuropathology in that Relationship.


2011 Karim Yamout       ADC       UCD
Abstracts = 2



Perfecting diagnosis of Alzheimer's disease using advanced computer modeling


Nikita Yaroshevsky       Non-ADC       Rollins College
Completed - No Publications
Proposal is complete.



Agreement between neuropathologic criteria for the diagnosis of Alzheimer's
disease


Zheng Zhang       NACC       
Abstract Published
Proposal is complete.



Joint random-effects transition models for multivariate longitudinal data


2013 Bo Zhang       Non-ADC       Oregon State University
Papers = 1




Large scale biomarker discovery and validation for Parkinson's disease (U01)


Jing Zhang       Non-ADC       University of Washington
Data File Sent
Proposal is complete.



Modeling Disease Progression in Alzheimer's and Parkinson's disease


Shenqiu Zhang       Non-ADC       University of Exeter Medical School
Data File Sent



Role of cholesterol in amyloid b-induced dysfunction of synaptic transmission
and initiation of neurodegeneration


Qi Zhang       Non-ADC       Vanderbilt University
Data File Sent



The association between benzodiazepine (BZD) use and dementia and/or cognitive
impairment using NACC data


Yuhai Zhang       NACC       Univeristy of Washington
Paper Submitted



Agreement between patient self-report health conditions and their medication
information


Rui Zhao       Non-ADC       University of Kentucky
Data File Sent



Learning optimal individualized intervention for the prevention of Alzheimer's
disease


Yingqi Zhao       Non-ADC       University of Wisconsin-Madison
Data File Sent



Analysis of binary long data in multi-center studies with missing covariates


2012 Andrew Zhou       NACC       University of Washington
Papers = 2 Abstracts = 1
Proposal is complete.



Applied Missing Data Analysis in Health Sciences


2011 Andrew Zhou       NACC       University of Washington
Papers = 3 Abstracts = 1



Estimate the ROC curve and its area in the presence of nonignorable
verification bias


2012 Andrew Zhou       NACC       NACC
Papers = 4 Abstracts = 2
Proposal is complete.



Dissociable Facets of Executive Dysfunction and Association with Preclinical
Alzheimers Disease


2013 Joyce Zhu       Non-ADC       Vanderbilt University
Abstracts = 1



Functional-Cognitive Marker of Preclinical AD


Joyce Zhu       Non-ADC       Vanderbilt University
Data File Sent