NACC productivity - last update 10/4/2018


The following list contains:

           ● all publications that use NACC resources;
           ● all publications for which has NACC provided direct analytic support and/or funding;
           ● all publications that have been submitted to NACC prior to acceptance;
           ● and all externally funded awards supported by NACC resources.

The list is to be used as a preliminary literature review and to help prevent the duplication of work. For current projects that have not yet resulted in publication or have been submitted for publication, please also see the list of completed and ongoing research.
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Research using NACC resources(TOTAL 872)

       Publications
         2018
1.   Agogo G, Ramsey C, Gnjidic D, Moga D, Allore H. Longitudinal associations between different dementia diagnoses and medication use jointly accounting for dropout. Int Psychogeriatr, In press 2018, NIHMS931116.

2.   Alosco ML, Sugarman MA, Besser LM, Tripodis Y, Martin B, Palmisano JN, Kowall NW, Au R, Mez J, DeCarli C, Stein TD, McKee AC, Killiany RJ, Stern RA. A Clinicopathological Investigation of White Matter Hyperintensities and Alzheimer's Disease Neuropathology. J Alzheimers Dis, 63:1347-1360, Published 2018, NIHMSID 983693.

3.   Alsaedi A, Mohammad N, Abdel-Qader I, Fong A. Extended Cox Proportional Hazard Model to Analyze and Predict Conversion From Mild Cognitive Impairment To Alzheimer's Disease. 8th IEEE Annual Computing and Communication Workshop and Conference, 131-136, Published 2018. (Abstract)

4.   Alsemari A, Boscarino JJ, Rosowsky E. Examining possible risk factors associated with frontotemporal dementia. Massachusetts Neuropsychological Society Science Symposium, Submitted 2018. (Abstract)

5.   Anderson SL, Daniel M. Depression's Influence on Cognitive Functioning in Older Adults who Develop Alzheimer's Dementia. International Neuropsychological Society 46th annual meeting, Accepted 2018. (Abstract)

6.   Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A, Deleuze JF, Duron E, Vardarajan BN, Reitz C, Goate AM, Huentelman MJ, Kamboh MI, Larson EB, Rogaeva E, St George-Hyslop P, Hakonarson H, Kukull WA, Farrer LA, Barnes LL, Beach TG...Neale BM. Analysis of shared heritability in common disorders of the brain. Science, In press 2018, NIHMS979389.

7.   Armstrong JJ, Godin J, Wallace L, Mitnitski A, Fisk J, Darvesh S, Andrew MK, Rockwood K. Frailty, neuropathology and clinical disease expression in dementia. J Neurol Neurosurg Psychiatry, Submitted 2018.

8.   Atayde AL, Fischer CE, Schweitzer TA, Munoz DG. Association of Declining Cognitive Status and Nighttime Behaviour Prevalence Along the Spectrum of Alzheimer's Disease Severity. AAIC 2018, Accepted 2018. (Abstract)

9.   Barnes J, Bartlett JW, Wolk DA, van der Flier WM, Frost C. Disease Course Varies According to Age and Symptom Length in Alzheimer's Disease. J Alzheimers Dis, In press 2018, PMC in process.

10.   Becker JE, Schaffert J, LoBue C, Adinoff B, Cullum M. History of alcohol misuse is associated with an earlier onset of Alzheimer's Disease. National Academy of Neuropsychology, Submitted 2018. (Abstract)

11.   Benge J. Quantitative and Qualitative Features of Executive Dysfunction in Frontotemporal and Alzheimer's Dementia. 2019 International Neuropsychological Meeting, Submitted 2018. (Abstract)

12.   Benge J. Supplementary and Discrepancy Scores for the UDS 3.0 Neuropsychological Normative Data. 2019 International Neuropsychological Meeting, Submitted 2018. (Abstract)

13.   Bergman C, Hilliard DD, Cunningham TD, Okhravi HR. Association of Statin Use and Statin Type on Cognitive Decline in Older Adults with Normal Cognition or Mild Cognitive Impairment: A 4-Year Analysis. JAMA Neurol, Submitted 2018.

14.   Besser L, Teylan M, Crary J, Mock C, Gauthreaux K, Barlow N, Chen Y, Kukull W. Clinical diagnoses among individuals with primary age-related tauopathy versus Alzheimer's neuropathology. AAIC 2018, Accepted 2018. (Abstract)

15.   Besser LM, Kukull W, Teylan M, Bigio E, Cairns N, Kofler J, Montine T, Schneider J, Nelson P. The Revised National Alzheimer's Coordinating Center's Neuropathology Form - Available Data and New Analyses. J Neuropathol Exp Neurol, 8:717-726, Published 2018, PMC6044344.

16.   Besser LM, Mock C, Teylan MA, Hassenstab J, Kukull WA, Crary JF. Cognitive impairment in primary age-related tauopathy versus Alzheimer's disease. AAIC 2018, Accepted 2018. (Abstract)

17.   Besser L, Rodriguez DA, McDonald N, Kukull W, Fitzpatrick AL, Rapp SR, Seeman T. Neighborhood built environment and cognition in non-demented older adults: The Multi-Ethnic Study of Atherosclerosis. Soc Sci Med, 200:27-35, Published 2018, PMC5893410.

18.   Blenkinsop A, Van der Flier WM, Wolk D, Lehmann M, Howard R, Frost C, Barnes J. Non-memory cognitive symptom development in Alzheimer's disease. Alzheimers Dement, Submitted 2018.

19.   Boggess MB, Barber JM, Caban-Holt A. Memory Complaints & Neuropsychological Testing of African Americans. Kentucky Psychological Foundation 2018 Spring Academic Conference, Accepted 2018. (Abstract)

20.   Bolton C. Neuropsychological Differentiation of Early Onset AD in Autopsy Confirmed Cases. American Academy of Clinical Neuropsychology Annual Meeting, Submitted 2018. (Abstract)

21.   Brent RJ. Estimating the Monetary Benefits of Medicare Eligibility for Reducing the Symptoms of Dementia. J Benefit Cost Anal, in press 2018, NIHMS 981434.

22.   Brent RJ. The value of a year's general education for reducing the symptoms of dementia. Appl Econ, 50:2812-2823, Published 2018, PMC5937534.

23.   Buckles VD, Xiong C, Bateman RJ, Allegri R, Benzinger TLS, Berman S, Cairns NJ, Chhatwal J, A D, Fagan AM, Ghetti B, Goate A, Graff-Radford N, Jassenstab J, Jucker M, Levin J, Marcus D, Martins R, Masters C, Mayeux R, McCue L, McDade E, Mori H, Moulder K, Paumier K, Ringman J, Rossor M, Salloway S, Schofield P, Morris JC. Rates of Cognitive Decline in Dominantly Inherited Versus Sporadic Alzheimer Disease. Neurology, Revision 2018.

24.   Burke S, Barnes C, Hanson K, Hu T, Duara R, Loewenstein D. Computerizing the conversation: A codified approach to consensus diagnosis. The Gerontological Society of America Annual Scientific Meeting, Submitted 2018. (Abstract)

25.   Burke S, Hu T, Fava NM, Li T, Rodriguez MJ, Schuldiner KL, Burgess A, Laird A. Sex differences in the development of mild cognitive impairment and probable Alzheimer's disease as predicted by hippocampal volume or white matter hyperintensities. J Women Aging, 43125, Published 2018, PMC6039284.

26.   Burke S, Hu T, O'Driscoll J, Alvarez D, Cottler L, Duara R. Factors Influencing Attrition in the National Alzheimer's Coordinating Center's Uniform Data Set. J Clin Epidemiol, Submitted 2018.

27.   Burke S, Wyman MF, Ma Y, Cadet TJ, Heard C, Umucu E, Gleason C. Differences in self versus informant-reported depression and apathy by race/ethnicity and cognitive status. The Gerontological Society of America Annual Scientific Meeting, Submitted 2018. (Abstract)

28.   Burke SL, Cadet T, Maddux M. Chronic health illnesses as predictors of mild cognitive impairment among African American older adults. J Natl Med Assoc, In press 2018, NIHMS948203.

29.   Burke SL, Hu T, Spadola CE, Burgess A, Li T, Naseh M, Cadet T. Mild Cognitive Impairment: Associations with sleep disturbance, Apolipoprotein E (APOE), and sleep medications. Sleep Med, Submitted 2018.

30.   Burke SL, Maramaldi P, Cadet C, Kukull W. Decreasing hazards of Alzheimer's disease with the use of antidepressants: mitigating the risk of depression and apolipoprotein E. Int J Geriatr Psychiatry, 33:200-211, Published 2018, PMC5711617.

31.   Burmaster SA, Schaffert J, Bailey K, LoBue C, Rossetti HC, Cullum CM. Implications of sex and race/ethnicity on history of traumatic brain injury and age of Alzheimer's disease onset. National Academy of Neuropsychology, Submitted 2018. (Abstract)

32.   Callahan BL. Operationalizing impaired performance in neuropsychological assessment: A comparison of the use of published versus sample-based normative data for the prediction of dementia. J Neuropsychol, Submitted 2018.

33.   Chan S, Dennison K, Conley J, Daniel M. Does Statin Use Mitigate Risk of Conversion to Alzheimer's Disease? The Association between Statin Use and Incidence of Alzheimer's Disease by Gender and Race. International Neuropsychological Society 46th Annual Meeting, 66, Published 2018. (Abstract)

34.   Chaney GA, Kamath C, Onyike C, Bakker A, Kamath V.. Neuropsychological Profiles in Autopsy-Confirmed Cases of Behavioral Variant Frontotemporal Dementia and Alzheimer's Disease. International Conference on Frontotemporal Dementias, Submitted 2018. (Abstract)

35.   Chaney GA, Onyike C, Bakker A, Kamath V. Relative Effects of Cognitive and Behavioral Dysfunction on Abnormal Feeding in Behavioral Variant Frontotemporal Dementia. International Conference on Frontotemporal Dementias, Submitted 2018. (Abstract)

36.   Chaney GA, Onyike C, Kamath V. The neuropsychological profile of abnormal feeding behavior in behavioral variant frontotemporal dementia. International Neuropsychological Society meeting, Accepted 2018. (Abstract)

37.   Chiou SH, Austin MD, Qian J, Betensky RA. Transformation model estimation of survival under dependent truncation and independent censoring. Biostatistics, Revision 2018.

38.   Cleary EG, Cifuentes M, Grinstein G, Brugge D, Shea TB. Association of Low-Level Ozone with Cognitive Decline in Older Adults. J Alzheimers Dis, 61:67-78, Published 2018, PMC5755393.

39.   Crum J, Wilson J, Sabbagh M. Does taking statins affect the pathological burden in autopsy confirmed Alzheimer's dementia?. Alzheimers Res Ther, In press 2018.

40.   Curcio N, Wilmoth K, LoBue C, Cullum M. Reliability of Medical History Reporting in Older Adults With and Without Cognitive Impairment. J Cent Nerv Syst Dis, Submitted 2018.

41.   Davis JJ. Performance validity in older adults: Observed versus predicted false positive rates in relation to number of tests administered. J Clin Exp Neuropsychol, In press 2018, NIHMS965403.

42.   Davis M, O'Connell T, Johnson S, Cline S, Merikle E, Martenyi F, Simpson KN. Estimating Alzheimer's disease progression rates from normal cognition through mild cognitive impairment and stages of dementia. Curr Alzheimer Res, Published 2018, PMC6156780.

43.   de Leon MJ, Pirraglia E, Osorio RS, Glodzik L, Saint-Louis L, Kim HJ, Fortea J, Fossati S, Laska E, Siegel C, Butler T, Li Y, Rusinek H, Zetterberg H, Blennow K. The nonlinear relationship between cerebrospinal fluid Abeta42 and tau in preclinical Alzheimer's disease. PLoS One, 13:e0191240, Published 2018, PMC5802432.

44.   De Wit L, Dotson VM, Smith GE. Progression to dementia in mild cognitive impairment in Alzheimer's etiology: contributions of vascular pathology and depression. J Int Neuropsychol Soc, Submitted 2018. (Abstract)

45.   DeMichele-Sweet M, Weamer EA, Klei L, Vranag DT, Hollingshead DJ, Seltman HJ, Sims R, Foroud T, Hernandez I, Moreno-Grau S, Tárraga L, Boada M, Ruiz A, Williams J, Mayeux R, Lopez OL, Kamboh MI, Devlin B, Sweet RA. Genetic Risk for Schizophrenia and Psychosis in Alzheimer Disease. Mol Psychiatry, 23:963-972, Published 2018, PMC5668212.

46.   Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Huentelman M, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Moghekar A, Del Aguila JL, Fernandez MV, Budde J, Hassenstab J, Fagan AM, Riemenschneider M, Petersen RC, Minthon L, Chao MJ, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Peskind ER, Li G, Davis LK, Sealock JM, Cox NJ, Alzheimer's Disease Neuroimaging Initiative, Alzheimer Disease Genetics Consortium, Goate AM, Bennett DA, Schneider JA, Jefferson AL, Cruchaga C, Hohman TJ. Sex-specific genetic predictors of Alzheimer's disease biomarkers. Acta Neuropathol, In press 2018, PMC in process.

47.   Deming Y, Dumitrescu L, Del-Aguila JL, Fernandez MV, Budde JP, Fagan AM, De Jager PL, Albert M, Moghekar A, Riemenschneider M, Petersen RC, Barnes L, Thambisetty M, Kunkle B, Gifford K, Bush WS, Chibnik LB, Kukull W, Crane PK, Resnick CM, Blennow K, Zetterberg H, Minthon L, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Johnson SC, Bennett DA, Schneider JA, Schellenberg G, Haines JL, Peskind ER, Li G, Alzheimer's Disease Neuroimaging Initiative (ADNI), The Alzheimer Disease Genetic Consortium (ADGC), Jefferson AL, Goate AM, Cruchaga C, Hohman TJ. Genome-wide association study reveals sex differences in genetic associations with cerebrospinal fluid endophenotypes for Alzheimer disease. AAIC 2018, Submitted 2018. (Abstract)

48.   Dorsman K, Erlhoff S, Llibre J. Characteristics of cognitively impaired Spanish-speaking individuals of Hispanic origin in the NACC database. AAIC Satellite Symposium: Buenos Aires, Accepted 2018. (Abstract)

49.   Fiford CM, Nicholas JM, Biessels GJ, Lane CA, Cardoso MJ, Barnes J. Higher late life blood pressure is associated with progressive hippocampal atrophy in Mild Cognitive Impairment and Alzheimer's disease. Neurology, Submitted 2018.

50.   Gallagher D, Kiss A, Lanctot K, Herrmann N. Depression and risk of Alzheimer's dementia: A longitudinal analysis to determine predictors of increased risk among older adults with depression. Am J Geriatr Psychiatry, In press 2018, NIHMS1502856.

51.   Gallagher D, Kiss A, Lanctot K, Herrmann N. Towards prevention of mild cognitive impairment in older adults with depression: a longitudinal analysis of potentially modifiable risk factors. Canadian Academy of Geriatric Psychiatry, Submitted 2018. (Abstract)

52.   Gallagher D, Kiss A, Lanctot K, Herrmann N. Towards prevention of mild cognitive impairment in older adults with depression: a longitudinal analysis of potentially modifiable risk factors. J Clin Psychiatry, Submitted 2018.

53.   Gallagher D, Lanctot K, Herrmann N. Depression and risk of Alzheimer's dementia: A longitudinal analysis to determine predictors of increased risk among older adults with depression. Canadian Association of Geriatric Psychiatry Meeting, Submitted 2018. (Abstract)

54.   Gangishetti U. CSF non-Beta-Amyloid, non-Tau Biomarkers for Clinical Alzheimer's Disease Stages. AAN 2018, Accepted 2018. (Abstract)

55.   Ganguli M, Albanese E, Seshadri S, Bennett DA, Lyketsos C, Kukull WA, Skoog I, Hendrie HC. Population Neuroscience: Dementia Epidemiology serving Precision Medicine and Population Health. Alzheimer Dis Assoc Disord, In press 2018, PMC5821530.

56.   Gefen T, Teylan M, Besser LM, Weintraub S. The Frontotemporal Lobar Degeneration Module (FTLD-MOD) of the Uniform Data Set: Performance on Language and Behavior Measures in Primary Progressive Aphasia (PPA) and Behavioral Variant Frontotempora. AAIC 2018, Accepted 2018. (Abstract)

57.   Giebel CM, Flanagan E, Sutcliffe C. Predictors of finance management in dementia: Managing bills and taxes matters. Int Psychogeriatr, In press 2018, PMC in process.

58.   Giebel CM, Knopman D, Mioshi E, Khondoker M. Distinguishing frontotemporal dementia from Alzheimer's disease through everyday function profiles: Trajectories of change. TBD, Revision 2018.

59.   Gnjidic D, Agogo GO, Ramsey CM, Moga DC, Allore H. The impact of dementia diagnosis on patterns of potentially inappropriate medication use among older adults. J Gerontol A Biol Sci Med Sci, In press 2018, PMC in process.

60.   Haaksma ML, Calderón-Larrañaga A, Rikkert MGMO, Melis RJF, Leoutsakos JS. Cognitive and functional progression in Alzheimer disease: A prediction model of latent classes. Int J Geriatr Psychiatry, 8:1057-1064, Published 2018, PMC6039270.

61.   Hackett K, Mis R, Divers R, Giovannetti T. Sources of Bias in Informant-Rated Everyday Functioning in MCI. 2019 International Neuropsychological Meeting, Submitted 2018. (Abstract)

62.   Hanfelt JJ, Peng L, Goldstein FC, Lah JJ. Latent classes of mild cognitive impairment are associated with clinical outcomes and neuropathology: Analysis of data from the National Alzheimer's Coordinating Center. Neurobiol Dis, 117:62-71, Published 2018, PMC in process.

63.   Hill BD, Sofko C, Thaler N, Gavett BE. Cognitive Intra-Individual Variability Increases with Neuropathological Burden and Clinical Dementia Rating Score. Neuropsychologia, Revision 2018.

64.   Hill BD, Sofko C, Thaler NS, Gavett BE, Burton J. Cognitive Intra-Individual Variability Increases as Mini Mental State Examination Score Declines: Further Support for Intra-Individual Variability as a Marker of Neuropathology. J Int Neuropsychol Soc, Revision 2018.

65.   Hohman TJ, Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Gifford K, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Bennett DA, Schneider JA, Jefferson AL, ADGC Collaborators. Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau. JAMA Neurol, In press 2018, NIHMS972166.

66.   Irimata KE, Dugger BN, Wilson JR. Impact of the presence of select cardiovascular risk factors on cognitive changes among dementia subtypes. Curr Alzheimer Res, In press 2018, NIHMSID 983107.

67.   Jiménez DA, Barnes J, Fiford CM, Malone IB. Greater atrophy of extra-hippocampal cortices in younger patients with Alzheimer's disease. Buenos Aires AAIC Satellite Symposium, Published 2018. (Abstract)

68.   John SE, Evans SA, Hanfelt J, Loring DW, Goldstein FC. Disparities in subjective memory complaint in African Americans and Caucasians. J Am Geriatr Soc, Submitted 2018.

69.   Jutten RJ, Amariglio RE, Marshall GA, Rentz DM, Van Der Flier WM, Scheltens P, Johnson KA, Sperling RA, Sikkes SAM, Papp KV. Characterizing clinical severity among biomarker positive individuals: Applying the 2018 NIA-AA research criteria for Alzheimer's disease to four large study cohorts. CTAD 2018, Submitted 2018. (Abstract)

70.   Kamara DM, Gangishetti U, Gearing M, Willis-Parker M, Zhao L, Hu WT, Walker LC. Cerebral Amyloid Angiopathy: Similarity in African-Americans and Caucasians with Alzheimer's Disease. J Alzheimers Dis, 62:1815-1826, Published 2018, PMC in process.

71.   Kaur A, Edland SD, Peavy GM. The MoCA-Memory Index Score: An Efficient Alternative to Paragraph Recall for the Detection of Amnestic Mild Cognitive Impairment. Alzheimer Dis Assoc Disord, 2:120-124, Published 2018, PMC5963962.

72.   Khachaturian AS, Hayden KM, Mielke MM, Tang Y, Lutz MW, Gold M, Kukull WA, Mohs R, Gauthier S, Molinuevo JL, Zetterberg H, Khachaturian ZS. New thinking about thinking, part two. Theoretical articles for Alzheimer's & Dementia. Alzheimers Dement, 14:703-706, Published 2018.

73.   Khachaturian AS, Hayden KM, Mielke MM, Tang Y, Lutz MW, Gustafson DR, Kukull WA, Mohs R, Khachaturian ZS. Future prospects and challenges for Alzheimer's disease drug development in the era of the NIA-AA Research Framework. Alzheimers Dement, 14:532-534, Published 2018.

74.   Kim J, Schweizer TA, Fischer CE, Munoz DG. Neuritic Plaque Load as Substrate of Psychosis in Cognitively Intact Subjects. AAIC 2018, Accepted 2018. (Abstract)

75.   Kim J, Schweizer TA, Fischer CE, Munoz DG. Psychosis In "Cognitively Asymptomatic" Elderly Subjects Is Associated with Neuritic Plaque Load, Not Neurofibrillary Tangles. Alzheimer Dis Assoc Disord, Published 2018, PMC6107422.

76.   Kim S, Char D, Lopez M, Lee GJ. Subtypes of Amnestic Mild Cognitive Impairments and Functional Status. International Neuropsychological Society, Submitted 2018. (Abstract)

77.   Kim S, Lopez M, Char D, Lee GJ. Differences in time to conversion between subtypes of Amnestic MCI. International Neuropsychological Society, Submitted 2018. (Abstract)

78.   Kirson NY, Scott Andrews J, Desai U, King SB, Schonfeld S, Birnbaum HG, Ball DE, Kahle-Wrobleski K. Patient Characteristics and Outcomes Associated with Receiving an Earlier Versus Later Diagnosis of Probable Alzheimer's Disease. J Alzheimers Dis, 61:295-307, Published 2018, PMC5734126.

79.   Koo G. Abnormal Nighttime Behaviours Across the Spectrum of Alzheimer's Disease. Curr Alzheimer Res, Submitted 2018.

80.   Kornak J, Fields J, Farmer S, Boeve B, Rosen H, Boxer A, Bove J, Brushaber D, Coppola G, Dheel C, Dickerson B, Dickinson S, Faber K, Fong J, Foroud T, Forsberg L, Gavrilova R, Gearhart D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grossman M, Haley D, Heuer H, Hsiao J, Hsiung R, Huey ED, Irwin D, Jones D, Jones L, Kantarci K, Karydas A, Knopman D, Kramer J, Kremers W, Kukull W, Lapid M, Lucente D, Mackenzie I, Manoochehri M, Miller B, Pearlman R, Petrucelli L, Potter M, Rademakers R, Rankin K, Rascovsky K, Sengdy P, Shaw L, Sutherland M, Syrjanen J, Tatton N, Taylor J, Toga A, Trojanowski J, Weintraub S, Wong B, Wszolek Z. Nonlinear n-score estimation for establishing cognitive norms from the National Alzheimer's Coordinating Center (NACC) dataset. AAIC 2018, Accepted 2018. (Abstract)

81.   Kornak J, Fields J, Kremers W, Farmer S, Brannelly P, Heuer HW, Forsberg L, Brushaber D, Rindels A, Dodge H, Weintraub S, Bove J, Coppola G, Dheel C, Dever R, Dickerson B, Dickinson S, Faber K, Fong J, Foroud T, Gavrilova R, Gearhart D, Ghoshal N, Goldman J, Graff-Radford J, Graff-Radford N, Grossman M, Haley D, Hsiao J, Hsiung R, Huey ED, Irwin D, Jones D, Jones L, Kantarci K, Karydas A, Knopman D, Kramer J, Kukull W, Lapid M, Ljubenkov P, Lucente D, Lungu C, Mackenzie I, Maoochehri M, McGinnis S, Miller BL, Pearlman R, Petrucelli L, Potter M, Rademakers R, Ramos EM, Rankin K, Rascovsky K, Sengdy P, Shaw L, Staffaroni A, Sutherland M, Syrjanen J, Tatton N, Taylor J, Toga A, Trojanowski J, Wong B, Wszolek Z, Boeve B, Boxer A, Rosen H. Nonlinear z-score estimation for establishing cognitive norms from the National Alzheimer's Coordinating Center (NACC) dataset for ARTFL/LEFFTDS. 11th International Conference on Frontotemporal Dementias, Submitted 2018. (Abstract)

82.   Lancour D, Naj A, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GD, Crovella M, Farrer LA, Kasif S, ADGC Collaborators. One for all and all for One: Improving replication of genetic studies through network diffusion. PLoS Genet, 4:e1007306, Published 2018, PMC5933817.

83.   Lee S, Zhou X, Vardarajan B, Reyes-Dumeyer D, Rajan KB, Wilson RS, Evans DA, Besser L, Kukull W, Bennett DA, Schupf N, Mayeux R, Barral S. Episodic Memory Performance in a Multiethnic Longitudinal Study of 13,979 Elderly. PLoS One, Submitted 2018.

84.   Lin M, Gong P, Yang T, Ye J, Albin R, Dodge H. Big Data Analytical Approaches to the NACC Dataset: Aiding Preclinical Trial Enrichment. Alzheimer Dis Assoc Disord, 32:18-27, Published 2018, PMC5854492.

85.   LoBue C, Woon FL, Rossetti HC, Hynan LS, Hart J, Cullum CM. Traumatic brain injury history and progression from mild cognitive impairment to Alzheimer disease. Neuropsychology, 32:401-409, Published 2018, PMC5975979.

86.   McMillan CT, Lee EB, Jefferson-George K, Naj A, Van Deerlin VM, Trojanowski JQ, Wolk DA. Alzheimer's genetic risk is reduced in primary age-related tauopathy: a potential model of resistance?. Ann Clin Transl Neurol, 8:927-934, Published 2018, PMC6093846.

87.   Michaud TL, Siahpush M, Farazi PA, Kim J, Yu F, Su D, Murman DL. The Association between Body Mass Index, and Cognitive, Functional, and Behavioral Declines for Incident Dementia. Alzheimer Dis Assoc Disord, Submitted 2018.

88.   Milani S. Optimal cutoffs for the Montreal Cognitive Assessment vary by race and ethnicity. Alzheimers Dement, Submitted 2018.

89.   Milani SA, Marsiske M, Striley C. Screening for Cognitive Impairment among Minority Populations using the Montreal Cognitive Assessment. Alzheimer's Association International Conference, Accepted 2018. (Abstract)

90.   Mis R, Devlin K, Drabick D, Giovannetti T. Heterogeneity of Informant-Reported Functional Performance in Mild Cognitive Impairment: A Latent Class Analysis of the Functional Activities Questionnaire. International Neuropsychological Society, Accepted 2018. (Abstract)

91.   Mitchell J, Cadet T, Burke S, Williams ED, Alvarez D. The Paradoxical Impact of Companionship on the Mental Health of Older African American Men. J Gerontol B Psychol Sci Soc Sci, 73:230-239, Published 2018, PMC5927098.

92.   Nance C, Ritter A, Justin MB, Banks SJ. Pathology of Rapid Cognitive Decline. International Neuropsychological Society 46th annual meeting, Accepted 2018. (Abstract)

93.   Nance C, Ritter A, Justin MB, Banks SJ. The Pathology of Rapid Cognitive Decline in Clinically Reported Alzheimer's Disease. Neurology, 90 (15 Supplement), Published 2018. (Abstract)

94.   Nevado A, del Rio D, Garcia-Pacios J, Maestú F. Loss of functional segregation in Alzheimer's Disease: A graph theory analysis of neuropsychological measures. J Neuropsychol, Submitted 2018.

95.   Nevado A, del Rio D, Garcia-Pacios J, Maestú F. Mapping the neuropsychological profile of Alzheimer's Disease using graph theory. Joint Sepex Sepneca Aip Conference, Submitted 2018. (Abstract)

96.   Nguyen TP, Schaffert J, LoBue C, Womack KB, Hart J, Cullum CM. Traumatic brain injury is not associated with significantly earlier onset of dementia with Lewy bodies. J Alzheimers Dis, Submitted 2018.

97.   Nunez N, Yin S, McCarthy J, Ducharme S. A comparative study examining prevalence of lifetime psychiatric disorders as a risk factor for Behavioral Variant Frontotemporal Dementia and Alzheimer's Disease. AAIC 2018, Accepted 2018. (Abstract)

98.   Nystrom N. Tobacco Exposure Cessation Is Associated with Incident Dementia and Nursing Homes. AAIC 2018, Accepted 2018. (Abstract)

99.   Oh G, Abner EL, Fardo DW, Freeman PR, Moga DC. Patterns and predictors of chronic opioid use in older adults: a retrospective cohort study. J Am Geriatr Soc, Submitted 2018.

100.   Parker AN, Schaffert J, Smith EE, Rossetti H, Cullum M. The role of Metabolic Syndrome in Alzheimer's disease progression: A retrospective study. National Academy of Neuropsychology, Submitted 2018. (Abstract)

101.   Perales J, Gauthreaux K, Flatt J, Teylan M, Resendez J, Kukull W, Chan K, Burns JM, Vidoni E. Risk of Dementia and Mild Cognitive Impairment among older adults in same-sex relationships. Int J Geriatr Psychiatry, Submitted 2018.

102.   Pillai JA, Appleby BS, Safar J, Leverenz JB. Rapidly Progressive Alzheimer's Disease in Two Distinct Autopsy Cohorts. J Alzheimers Dis, 3:973-980, Published 2018, PMC in process.

103.   Qian W, Fischer CE, Millikin C, Ismail Z, Smith, EE, Lix LM, Munoz DG, Schweizer, TA. Atrophy in the Default Mode, Central Executive, and Salience Networks following the development of delusions in patients with Alzheimer's disease. TBD, Revision 2018.

104.   Qian W, Fischer CE, Schweizer TA, Munoz DG. Association between psychosis phenotype and APOE genotype on the clinical profiles of Alzheimer's disease. Curr Alzheimer Res, 15:187-194, Published 2018, PMC in process.

105.   Qian W, Schweizer TA, Churchill NW, Millikin C, Ismail Z, Smith EE, Lix LM, Munoz DG, Barfett J, Shelton P, Rajji TK, Fischer CE. Grey matter changes associated with the development of delusions in Alzheimer's disease: A longitudinal and cross-sectional voxel-based morphometry study. Am J Geriatr Psychiatry, Submitted 2018.

106.   Qiu Y, Jacobs D, Messer K, Salmon D, Feldman H. Identifying Cognitive Subtypes of Mild-to-Moderate Alzheimer's Disease Using the National Alzheimer's Coordinating Center Uniform Dataset Neuropsychological Test Battery. American Academy of Neurology, Accepted 2018. (Abstract)

107.   Ramsey CM, Gnjidic D, Agogo GO, Allore H, Moga D. Longitudinal patterns of potentially inappropriate medication use following incident dementia diagnosis. Alzheimers Dement (N Y), In press 2018, PMC5738721.

108.   Rascovsky K, Teylan MA, McMillan CT, Barlow N, Gonzalez HM, Salmon DP, Galasko DR, Besser LM, Kukull WA, Grossman M. Risk factors for clinical AD in US Latino populations: an analysis of the NACC database. AAIC 2018, Accepted 2018. (Abstract)

109.   Rindge M. Neuropsychological, Mood, and Functional Predictors of Conversion from Mild Cognitive Impairment to Alzheimer's Dementia Confirmed by Autopsy: A Pilot Study. International Neuropsychological Society Conference 2018, Published 2018. (Abstract)

110.   Scelsi MA, Khan RR, Lorenzi M, Christopher L, Greicius MD, Schott JM, Ourselin S, Altmann A. Genetic study of multimodal imaging Alzheimer's disease progression score implicates novel loci. Brain, 7:2167-2180, Published 2018, PMC6022660.

111.   Schaffert J, LoBue C, White CL, Chiang HS, Didehbani N, Lacritz L, Rossetti H, Dieppa M, Hart J, Cullum CM. Traumatic Brain Injury History Is Associated With an Earlier Age of Dementia Onset in Autopsy-Confirmed Alzheimer's Disease. Neuropsychology, 32:410-416, Published 2018, PMC5975092.

112.   Smith EE, Muzikansky A, McCreary CR, Batool S, Viswanathan A, Dickerson BC, Johnson K, Greenberg SM, Blacker D. Impaired Memory is More Closely Associated with Brain Beta-Amyloid than Leukoaraiosis in Hypertensive Patients with Cognitive Symptoms. PLoS One, 13:e0191345, Published 2018, PMC5790236.

113.   Stasenko A. Sensitivity of the Multilingual Naming Test (MINT) to Level of Cognitive Impairment Across the Alzheimer's Disease (AD) Spectrum. International Neuropsychological Society Annual Meeting 2018, Accepted 2018. (Abstract)

114.   Stickel A, McKinnon A, Ryan L. Memory and processing speed predict functional independence differentially in non-Hispanic and Hispanic White middle aged and older adults. Arizona Alzheimer's Consortium, Submitted 2018. (Abstract)

115.   Stipho F, Jackson R, Sabbagh MN. Pathologically confirmed AD in Apo E 2 homozygotes is rare but does occur. J Alzheimers Dis, 62:1527-1530, Published 2018, PMC in process.

116.   Sugarman MA, Alosco ML, Tripodis Y, Steinberg EG, Stern RA. Neuropsychiatric symptoms and the diagnostic stability of mild cognitive impairment. J Alzheimers Dis, In press 2018, PMC in process.

117.   Sugarman MA, McKee AC, Stein TD, Tripodis Y, Besser LM, Martin B, Palmisano JN, Steinberg EG, O'Connor MK, Au R, McClean M, Killiany R, Mez J, Weiner MW, Kowall NW, Stern RA, Alosco ML. Failure to Detect Association Between Traumatic Brain Injury and Alzheimer's Disease Neuropathology and Dementia: An Examination in 4,761 Autopsy Participants from the NACC Data Set. Alzheimers Dement, Submitted 2018.

118.   Suhr J. Cognitive and Neuropsychiatric Symptoms and their Correlates in Individuals with Alzheimer's Disease across Different Racial/Ethnic Groups. TBD, Submitted 2018. (Abstract)

119.   Teylan M, Gauthreaux K, Besser LM, Barlow N, Kukull WA. Rheumatoid arthritis, inflammation treatment, and Alzheimer's disease: a cross-sectional descriptive study using the NACC database. AAIC 2018, Accepted 2018. (Abstract)

120.   Ting S, Chia PS, Hameed S. Anatomical Correlation of Phonological Related Error of Reading in Primary Progressive Aphasia. TBD, Revision 2018.

121.   Ting SK, Foo H, Chia PS, Hameed S, Ng KP, Ng A, Kandiah N. Dyslexic Characteristics of Chinese-Speaking Semantic Variant of Primary Progressive Aphasia. J Neuropsychiatry Clin Neurosci, 30:31-37, Published 2018, PMC5794526.

122.   Ting SKS, Chen C, Li H, Hameed S, Ng A, Tan E-K, Ng KP, Kandiah N. Clinical Characteristics of Pathological Confirmed Early Onset Dementia with Lewy Bodies. JAMA Neurol, Submitted 2018.

123.   Tse KH, Cheng A, Ma F, Herrup K. DNA damage-associated oligodendrocyte degeneration precedes amyloid pathology and contributes to Alzheimer's disease and dementia. Alzheimers Dement, In press 2018, NIHMS943919.

124.   Vöglein J, Paumier K, Cairns N, Franklin EE, Perrin RJ, Xiong C, Bateman RJ, Danek A, Morris JC, Levin J. Clinical correlates of Lewy body pathology in autosomal dominant Alzheimer's disease. AAIC 2018, Accepted 2018. (Abstract)

125.   Vöglein J, Paumier K, Jucker M, Preische O, McDade E, Hassenstab J, Benzinger TL, Noble JM, Berman SB, Graff-Radford NR, Ghetti B, Farlow MR, Chhatwal J, Salloway S, Xiong C, Karch CM, Cairns N, Mori H, Schofield PR, Masters CL, Goate A, Phil D, Buckles V, Fox N, Rossor M, Chrem P, Allegri R, Ringman JM, Höglinger G, Steiner H, Dieterich M, Haass C, Laske C, Morris JC, Bateman RJ, Danek A, Levin J. Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease. Brain, Submitted 2018.

126.   Wang Q, Guo L, Thompson PM, Jack CR, Dodge H, Zhan L, Zhou J. The Added Value of Diffusion-Weighted MRI-Derived Structural Connectome in Evaluating Mild Cognitive Impairment: A Multi-Cohort Validation. J Alzheimers Dis, 64:149-169, Published 2018, PMC in process.

127.   Wang T, Qiu JL, Qiu RG, Yu M. Early Detection Models for Persons with Probable Alzheimer's Disease with Deep Learning. IEEE IMCEC, Accepted 2018. (Abstract)

128.   Wang T, Qiu RG, Yu M. Predictive Modeling of the Progression of Alzheimer's Disease with Recurrent Neural Networks. Sci Rep, 8:9161, Published 2018, PMC in process.

129.   Weintraub S, Besser L, Dodge HH, Teylan M, Ferris S, Goldstein FC, Giodani B, Kramer J, Loewenstein D, Marson DC, Mungas D, Salmon DP, Welsh-Bohmer KA, Zhou XH, S.D. S, Atri A, Kukull W, Phelps C, Morris JC. Version 3 of the Alzheimer's Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS). Alzheimer Dis Assoc Disord, 32:10-17, Published 2018, PMC5821520.

130.   Werry A, Daniel M. Influence of Demographic Variables on Measures of Memory and Language for Spanish Speaking Hispanic and Matched White Older Adults. National Academy of Neuropsychology, Submitted 2018. (Abstract)

131.   Werry A, Daniel M. The Influence of Demographic Variables on Normal Neuropsychological Test Performance in English Speaking Hispanic and Matched White Older Adults. National Academy of Neuropsychology, Submitted 2018. (Abstract)

132.   Werry AE, Daniel M, Bergström B. Ethnic Group Differences in Normal Neuropsychological Test Performance for Older Adults. Neuropsychology, Submitted 2018.

133.   Werry AE, Daniel M. Influence of Demographic Variables on Measures of Attention and Working Memory in Older Adults of Different Races. J Int Neuropsychol Soc, 24(S1):138, Published 2018. (Abstract)

134.   Wilmoth K, LoBue C, Clem MA, Reddy R, Hynan LS, Didehbani N, Bell K, Womack KB, Hart J, Jr., Batjer H, Cullum CM. Consistency of traumatic brain injury reporting in older adults with and without cognitive impairment. Clin Neuropsychol, 32:524-529, Published 2018, PMC5851823.

135.   Wyman MF, Norton DL, Ma Y, Burke SL, Walaszek A, Umucu E, Zuelsdorff M, Nystrom NC, Carlsson CM, Johnson SC, Asthana S, Gleason CE. The Association of Depressive Symptoms, Apathy, and Antidepressant Use with Incident MCI and Dementia in the NACC Dataset. AAIC 2018, Accepted 2018. (Abstract)

136.   Wyman-Chick KA, Erickson LO, Rosenbloom MH, Barclay TRJ, J, Barrett MJ. Prevalence of Neuropsychiatric and Motor Symptoms in Prodromal Dementia with Lewy Bodies. AAIC 2018, Accepted 2018. (Abstract)

137.   Yu W, Kim J, Park T. Estimation of Area Under the ROC Curve under nonignorable verication bias. Statistic Sinica, In press 2018, PMC in process.

138.   Zhou X, Chen Y, Mok KY, Zhao Q, Chen K, Chen Y, Hardy J, Li Y, Fu AKY, Guo Q, Ip NY, Alzheimer's Disease Neuroimaging I.. Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer's disease pathogenesis. Proc Natl Acad Sci U S A, 8:1697-1706, Published 2018, PMC5828602.

 
         2017
139.   Agogo GO, Gnjidic D, Moga D, Allore H. Associations between dementia status and polypharmacy jointly accounting for dropout and death. Innov Aging, 1:19, Published 2017. (Abstract)

140.   Alosco ML, Duskin J, Besser LM, Martin B, Chaisson CE, Gunstad J, Kowall NW, McKee AC, Stern RA, Tripodis Y. Modeling the Relationships Among Late-Life Body Mass Index, Cerebrovascular Disease, and Alzheimer's Disease Neuropathology in an Autopsy Sample of 1,421 Subjects from the National Alzheimer's Coordin. J Alzheimers Dis, 3:953-968, Published 2017, PMC5526463.

141.   Anderson RM, Hadjichrysanthou C, Evans S, Wong MM. Why do so many clinical trials of therapies for Alzheimer's disease fail?. Lancet, 390:2327-2329, Published 2017.

142.   Anderson SL, Werry AE, Daniel M. Depression Influence on Executive Functioning and Processing Speed after accounting for Cerebrovascular Risk in Non-Demented Older Adults. J Int Neuropsychol Soc, 23:s1, Published 2017. (Abstract)

143.   Archer M, Hall PH, Morgan JC. Accuracy of Clinical Diagnosis of Alzheimer's Disease in Alzheimer's Disease Centers (ADCs). Alzheimers Dement, 13:P800-P801, Published 2017. (Abstract)

144.   Bateman DR, Tam JW, Gao KA, Apostolova LG. Neuropsychiatric Symptoms and Neuropathology Correlation in Frontotemporal Lobar Degeneration. Alzheimers Dement, 7:479, Published 2017. (Abstract)

145.   Beekly D, Schwabe-Fry K, Bollenbeck M, Thomas G, DeCarli C, Carmichael OT, Kukull WA. The National Alzheimer's Coordinating Center: Development of the MRI, PET and CSF Biomarker Databases. Alzheimers Dement, 13:P157, Published 2017. (Abstract)

146.   Bell SP, Liu D, Samuels LR, Shah AS, Gifford KA, Hohman TJ, Jefferson AL. Late-Life Body Mass Index, Rapid Weight Loss, Apolipoprotein E epsilon4 and the Risk of Cognitive Decline and Incident Dementia. J Nutr Health Aging, 21:1259-1267, Published 2017, PMC5736008.

147.   Bernier PJ, Gourdeau C, Carmichael PH, Beauchemin JP, Verreault R, Bouchard RW, Kroger E, Laforce R, Jr. Validation and diagnostic accuracy of predictive curves for age-associated longitudinal cognitive decline in older adults. CMAJ, 189:E1472-E1480, Published 2017, PMC5714699.

148.   Berres M, Monsch AU, Spiegel R. Putting the PGSA to the test: Rates of progression to dementia in five studies with MCI patients. CTAD Meeting, Boston, Accepted 2017. (Abstract)

149.   Besser LM, Mock C, Teylan MA, Hassenstab J, Kukull WA, Crary JF. Differences in cognitive impairment in primary age-related tauopathy versus Alzheimer's disease. Neurology, Submitted 2017.

150.   Besser LM, W McDonald NC, Song Y, Kukull WA, W Rodriguez DA. Neighborhood Environment and Cognition in Older Adults: A Systematic Review. Am J Prev Med, 53:241-251, Published 2017, PMC5522645.

151.   Besser LM, Crary JF, Mock C, Kukull WA. Comparison of symptomatic and asymptomatic persons with primary age-related tauopathy. Neurology, 89:1707-1715, Published 2017, PMC5644462.

152.   Besser L, Nation D, Hughes T, Barlow N, Kukull W. Pulse pressure in late-life and Alzheimer's and cerebrovascular neuropathology. Alzheimers Dement, 13:P1473, Published 2017. (Abstract)

153.   Bilbrey AC, Humber BC, Plowey E, Garcia I, Chennapragada L, Rosen A, Gallagher-Thomson D. The Impact of Latino Values and Cultural Beliefs on Brain Donation: Results of a Pilot Study to Develop Culturally Appropriate Materials and Methods to Increase Rates of Brain Donation in this Under-. Clin Gerontol, In press 2017, PMC in process.

154.   Boeve B, Rosen HJ, Boxer A, Coppola G, Dheel C, Dickerson B, Fields J, Fong J, Gavrilova R, Ghoshal N, Goldman JG, Graff-Radford NR, Grossman M, Heuer I, Hsiao J, Huey ED, Irwin D, Knopman DS, Kornak J, Kraft R, Kukull W. Kramer J, Mackenzie I, Miller BL, Miller M, Phelps C, Rademakers R, Rankin K, Sutherland M, Syrjanen J, Taylor J, Weintraub S, Wszolek Z. Phenoconversion from Asymptomatic to Symptomatic FTLD: Preliminary Data in the LEFFTDS Cohort. Alzheimers Dement, 13:P739, Published 2017. (Abstract)

155.   Borges LG, Rademaker AW, Bigio EH, Mesulam M, Weintraub S. APOE ε4 is a lesser risk factor for frontotemporal than amnestic dementia with Alzheimer's neuropathology. AAN 2017, Submitted 2017. (Abstract)

156.   Borges LG, Rademaker AW, Bigio EH, Mesulam M, Weintraub S. Neuropsychiatric Symptoms Related to Neuropathologic vs. Clinical Diagnosis of Dementia. AAN 2017, Submitted 2017. (Abstract)

157.   Brenowitz WD, Han F, Kukull W, Nelson P. Treated hypothyroidism is associated with cerebrovascular disease but not Alzheimer's disease pathology in older adults. Neurobiol Aging, 62:64-71, Published 2017, PMC5743774.

158.   Brenowitz WD, Hubbard RA, Hawes SE, Keene CD, Longstreth WT, Crane PK, Larson EB, Kukull WA. Comorbid brain conditions in older adults with clinical Alzheimer's disease. Am J Epidemiol, Accepted 2017. (Abstract)

159.   Brenowitz WD, Hubbard RA, Keene CD, Hawes SE, Longstreth T, Woltjer RL, Kukull WA. Mixed neuropathologies and estimated rates of clinical progression in a large autopsy sample. Alzheimers Dement, 6:654-662, Published 2017, PMC5438283.

160.   Brenowitz WD, Hubbard RA, Keene D, Hawes SE, Longstreth WT, Jr., Woltjer RL, Kukull WA. Mixed neuropathologies and associations with domain-specific cognitive decline. Neurology, 89:1773-1781, Published 2017, PMC5664309.

161.   Brenowitz WD, Keene CD, Hawes SE, Hubbard RA, Longstreth Jr WT, Woltjer RL, Crane PK, Larson EB, Kukull WA. Alzheimer's disease neuropathologic change, Lewy body disease, and vascular brain injury in clinic- and community-based samples. Neurobiol Aging, 53:83-92, Published 2017, PMC5385292.

162.   Burke SL, Cadet T, Alcide A, O'Driscoll J, Maramaldi P. Psychosocial risk factors and Alzheimer's disease: the associative effect of depression, sleep disturbance, and anxiety. Aging Ment Health, 43108, Published 2017, PMC5924446.

163.   Burke SL, O'Driscoll J, Alcide A, Li T. Moderating risk of Alzheimer's disease through the use of anxiolytic agents. Int J Geriatr Psychiatry, 32:1312-1321, Published 2017, PMC5441966.

164.   Callahan BL, Keith J, Duchesne S, Black SE. Autopsy-verified pathological clusters in Alzheimer's disease and longitudinal cognitive performance. Brain, Submitted 2017.

165.   Callahan BL. Early signs of dementia in bipolar disorder. Am J Psychiatry, Submitted 2017.

166.   Callahan BL. Early Signs of Dementia in Bipolar Disorder. International Neuropsychological Society 46th Annual Meeting, Submitted 2017. (Abstract)

167.   Callahan BL. Norms generated from local samples are more sensitive to early dementia than are published norms. Canadian Conference on Dementia, Submitted 2017. (Abstract)

168.   Calvert K, Boeve B, Rosen HJ, Boxer A, Dheel C, Dickerson B, Fields J, Gavrilova R, Ghoshal N, Goldman JG, Graff-Radford NR, Grossman M, Heuer I, Hsiung R, Huey ED, Hughes S, Irwin D, Knopman DS, Kornak J, Kraft R, Kramer J, Lapid M, Mackenzie I, Miller BL, Miller M, Rankin K, Syrjanen J, Weintraub S, Wszolek Z. Quality of Life Among Subjects and Informants in Familial Frontotemporal Dementia: Preliminary Data in the LEFFTDS Cohort. Alzheimers Dement, 13:P376, Published 2017. (Abstract)

169.   Caputo A, Racine A, Paule I, Martens E, Tariot P, Langbaum JB, Thomas RG, Hendrix S, Ryan JM, Lopez C, Graf A. Rationale for selection of primary endpoints in the Alzheimer Prevention Initiative Generation Study in cognitively healthy APOE4 homozygotes. Alzheimers Dement, 13:P1452, Published 2017. (Abstract)

170.   Carr JS. The Role of Immune Modulatory Regions. University of California, San Francisco, Defended 2017.

171.   Ceide M, Cohen C. Predictors of Cognitive Change in Alzheimer's Dementia. J Alzheimers Dis, Submitted 2017.

172.   Ceide M, Cohen C. Predictors of Cognitive Improvement in Alzheimer's Dementia. World Psychiatric Association World Congress of Psychiatry, Accepted 2017. (Abstract)

173.   Cho H, Harel O, Mattews GJ. Confidence intervals for the area under the receiver operating characteristic curve in the presence of ignorable missing data. Int Stat Rev, In press 2017, PMC in process.

174.   Christopher L, Napolioni V, Khan R, Han S, Greicius M. GWAS of Decline in Posterior Cingulate Glucose Metabolism Identifies a Protective Variant in SMEK1. Alzheimers Dement, 13:P220-P221, Published 2017. (Abstract)

175.   Clem MA, Holliday RP, Pandya SY, Hynan LS, Lacritz LH, Woon FL. Predictors That a Diagnosis of Mild Cognitive Impairment Will Remain Stable 3 Years Later. Cogn Behav Neurol, 30:8-15, Published 2017, PMC5399514.

176.   Clem MA, LoBue C, Wilmoth K, Hart J, Jr., Cullum CM. History of Depression is Associated with Earlier Age of Diagnosis in Alzheimer's Disease. J Int Neuropsychol Soc, Accepted 2017. (Abstract)

177.   Dadar M, Maranzano J, Misquitta K, Anor CJ, Fonov VS, Tartaglia AC, Carmichael O, DeCarli C, Collins DL. Performance Comparison of 10 Different Classification Techniques in Segmenting White Matter Hyperintensities in Aging. Neuroimage, 157:233-249, Published 2017, PMC in process.

178.   Dheel C, Boeve B, Rosen HJ, Boxer A, Coppola G, Dickerson B, Faber K, Fields J, Foroud T, Gavrilova R, Ghoshal N, Goldman JG, Graff-Radford NR, Grossman M, Heuer H, Hsiao J, Huey ED, Irwin D, Kantarci K, Karydas A, Knopman DS, Kornak J, Kramer J, Kukull W, Mackenzie I, Miller BL, Phelps C, Rademakers R, Rankin K, Shaw L, Sutherland M, Syrjanen J, Toga AW, Trojanowski JQ, Vetor A, Weintraub S, Wszolek Z. Characteristics and Progress on the Initial 284 Subjects in the Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects (LEFFTDS) Protocol. Alzheimers Dement, 13:P345, Published 2017. (Abstract)

179.   Duskin D, Alosco ML, Besser LM, Martin B, Chaisson CE, Gunstad, J, Kowall NW, McKee AC, Stern RA, Tripodis Y. Modeling the Relationships Among Late-Life Body Mass Index, Cerebrovascular Disease, and Alzheimer's Disease Neuropathology in 1,421 Participants from the National Alzheimer's Coordinating Center Neur. Neurology, P2.093, Published 2017. (Abstract)

180.   Espinosa R, Cline S, Davis M, Johnson S, Martenyi F. Evaluating the potential impact of improved diagnostic criteria on the accuracy and timing of Lewy body dementia (LBD) diagnosis. SMDM 39th Annual North American Meeting, Accepted 2017. (Abstract)

181.   Evans S, McRae-McKee K, Ower A, Hadjichrysanthou C, Wong MM, Wolf F, Anderson RM. Rates of progression between diagnostic groups towards Alzheimer's disease: Comparison between cohort studies. Alzheimers Dement, 13:P351, Published 2017. (Abstract)

182.   Fields J, Boeve B, Rosen H, Boxer A, Coppola G, Dheel C, Dickerson B, Fong J, Gavrilova R, Ghoshal N, Goldman J, Graff-Radford N, Grossman M, Heuer H, Hsiao J, Huey E, Irwin D, Kantarci K, Karydas A, Knopman D, Kornak J, Kraft R, Kukull, W Kramer J, Mackenzie I, Miller B, Miller M, Phelps C, Rademakers R, Rankin K, Sutherland M, Syrjanen J, Taylor J, Weintraub D, Wszolek Z. Cognitive Changes in Phenoconverters from Asymptomatic to Minimally Symptomatic FTLD: Preliminary Data in the LEFFTDS Cohort. International Neuropsychological Society's Mid-Year Congress, Accepted 2017. (Abstract)

183.   Fiford C, Leung KK, Cardoso MJ, Nicholas J, Barnes J. Simultaneous changes in blood pressure, cognition and brain volume in ageing, mild cognitive impairment and Alzheimer's disease. Alzheimers Dement, 13:P70-P71, Published 2017. (Abstract)

184.   Fischer C, Qian W, Schweizer T, Ismail Z, Smith EE, Millikin C, Munoz D. Determining the impact of psychosis on rates of false-positive and false-negative diagnosis in Alzheimer's disease. Alzheimers Dement (N Y), 3:385-392, Published 2017, PMC5651446.

185.   Goldstein FC, Hajjar IM, Dunn CB, Levey AI, Wharton W. The Relationship Between Cognitive Functioning and the JNC-8 Guidelines for Hypertension in Older Adults. J Gerontol A Biol Sci Med Sci, 1:121-126, Published 2017, PMC5155663.

186.   Goldstein FC, Steenland K, Zhao L, Wharton W, Levey AI, Hajjar I. Proton Pump Inhibitors and Risk of Mild Cognitive Impairment and Dementia. J Am Geriatr Soc, 65:1969-1974, Published 2017.

187.   Green AR, Segal J, Tian J, Oh E, Roth DL, Hilson L, Dodson JL, Boyd CM. Use of Bladder Antimuscarinics in Older Adults with Impaired Cognition. J Am Geriatr Soc, 2:390-394, Published 2017, PMC5521963.

188.   Guo H, Siu W, D'Arcy RCN, Black S, Grajauskas L, Shang L, Diggle J, Rockwood K, Song X. MRI assessment of whole-brain structural changes in aging. Clin Interv Aging, 12:1251-1270, Published 2017, PMC5557118.

189.   Haaksma M, Calderón-Larrañaga A, Rikkert MGMO, Melis RJF, Leoutsakos JMS. Latent classes of course in Alzheimer's Disease show an optimistic prognosis for the majority of patients. International College of Geriatric Psychoneuropharmacology, Accepted 2017. (Abstract)

190.   Hadjichrysanthou C, McRae-McKee K, Evans S, Wong M, Wolf F, Anderson RM. Cognitive improvement in Alzheimer's disease recorded in longitudinal epidemiological studies: is it real or just a result of misdiagnosis?. Alzheimers Dement, Submitted 2017.

191.   Han F, Bonnett T, Brenowitz WD, Teylan MA, Besser LM, Cao K, Zhou XH, Gao Y, Kukull WA. Association between antidepressant use and incident MCI in older adults with depression. Alzheimers Dement, 13:P1520-P1521, Published 2017. (Abstract)

192.   Han J, Besser L, Xiong C, Kukull W, Morris JC. Cholinesterase Inhibitor Use and Cognitive Decline in Mild Cognitive Impairment and Mild Dementia due to Alzheimer Disease. Alzheimers Dement, 13:P1054, Published 2017. (Abstract)

193.   Han J, Besser LM, Xiong C, Kukull WA, Morris JC. Cholinesterase Inhibitor May Not Benefit MCI and Mild AD Dementia. Neurology, Submitted 2017.

194.   Heffernan AL, Chidgey C, Peng P, Masters CL, Roberts BR. The neurobiology and age-related prevalence of the ε4 allele of apolipoprotein E in Alzheimer's disease cohorts. J Mol Neurosci, 60:316-324, Published 2017, PMC5531868.

195.   Heublein C. An Exploration of Prediction on Caregivers' Behavioral Assessments of Individuals with Dementia. Capella University, Defended 2017.

196.   Hobel Z, Raghupathy D, Pa J. Apolipoprotein E ε4 dose effects on hippocampal volume and cognition in older adults with normal cognition, mild cognitive impairment, and Alzheimer's disease for the Alzheimer's Disease. Neurology, Submitted 2017.

197.   Hughes S, Boeve B, Rosen HJ, Boxer A, Calvert K, Dheel C, Dickerson B, Fields J, Gavrilova R, Ghoshal N, Goldman JG, Graff-Radford NR, Grossman M, Heuer I, Hsiung R, Huey ED, Irwin D, Knopman DS, Kornak J, Kraft R, Kramer J, Mackenzie I, Miller BL, Miller M, Rankin K, Syrjanen J, Weintraub S, Wszolek Z. Caregiver Burden in Familial Frontotemporal Dementia Subjects: Preliminary Data in the LEFFTDS Cohort. Alzheimers Dement, 13:P722-P723, Published 2017. (Abstract)

198.   Ighodaro E, Abner E, Fardo D, Schmitt F, Kryscio R, Jicha G, Neltner J, Monsell S, Kukull W, Appiah F, Bachstetter A, Van Eldik L, Nelson P. Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals. J Cereb Blood Flow Metab, 37:201-216, Published 2017, PMC5363738.

199.   Ighodaro ET, Nelson PT, Kukull W, Schmitt FA, Abner EL, Caban-Holt A, Bardach SH, Hord DC, Glover CM, Jicha GA, Van Eldik LJ, Byrd AX, Fernander A. Challenges and Considerations Related to Studying Dementia in Blacks/African Americans. J Alzheimers Dis, In press 2017, PMC5889715.

200.   Irimata K. Impact of the presence of select cardiovascular risk factors on cognitive change. American Public Health Association 2017 Annual Meeting Expo, Accepted 2017. (Abstract)

201.   Irwin DJ, Grossman M, Weintraub D, Hurtig HI, Duda JE, Xie SX, Lee EB, Van Deerlin VM, Lopez OL, Kofler JK, Nelson PT, Jicha GA, Woltjer R, Quinn JF, Kaye J, Leverenz JB, Tsuang D, Longfellow K, Yearout D, Kukull WA, Keene CD, Montine TJ, Zabetian CP, Trojanowski JQ.. Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis. Lancet Neurol, 1:55-56, Published 2017, PMC5181646.

202.   Jefferson-George KS, Wolk DA, Lee EB, McMillan CT. Cognitive decline associated with pathological burden in primary age-related tauopathy. Alzheimers Dement, 13:1048-1053, Published 2017, PMC5585025.

203.   Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, Foroud TM, Friedland RP, Goate AM, Graff-Radford NR, Hendrie H, Hall KS, Hamilton-Nelson KL, Inzelberg R, Kamboh MI, Kauwe JS, Kukull WA, Kunkle BW, Kuwano R, Larson EB, Logue MW, Manly JJ, Martin ER, Montine TJ, Mukherjee S, Naj A, Reiman EM, Reitz C, Sherva R, St George-Hyslop PH, Thornton T, Younkin SG, Vardarajan BN, Wang LS, Wendlund JR, Winslow AR, Haines J, Mayeux R, Pericak-Vance MA, Schellenberg G, Lunetta KL, Farrer LA, ADGC Collaborators. Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimers Dement, 13:727-738, Published 2017, PMC5496797.

204.   Jutkowitz E, Kane RL, Gaugler J, Maclehose R, Dowd B, Kuntz K. Societal and family lifetime cost of dementia: implications for policy. J Am Geriatr Soc, 65:2169-2175, Published 2017, PMC5657516.

205.   Jutkowitz E, Maclehose R, Gaugler JE, Dowd B, Kuntz KM, Kane RL. Risk Factors Associated With Cognitive, Functional, and Behavioral Trajectories of Newly Diagnosed Dementia Patients. J Gerontol A Biol Sci Med Sci, 2:251-258, Published 2017, PMC5344797.

206.   Karlsson IK, Ploner A, Song C, Gatz M, Pedersen NL, Hagg S, ADGC Collaborators. Genetic susceptibility to cardiovascular disease and risk of dementia. Transl Psychiatry, 7:e1142, Published 2017, PMC5534941.

207.   Katsumata Y, Nelson PT, Ellingson SR, Fardo DW, ADGC Collaborators. Gene-based association study of genes linked to hippocampal sclerosis of aging neuropathology: GRN, TMEM106B, ABCC9, and KCNMB2. Neurobiol Aging, 193:e17-193.e25, Published 2017, PMC5385271.

208.   Katsumata Y, Nelson PT, Ellingson SR, Fardo DW. Genetic Association of the ABCC9 Gene with Hippocampal Sclerosis of Aging Neuropathology. Innov Aging, 1:255, Published 2017. (Abstract)

209.   Kielb S, Rogalski E, Weintraub S, Rademaker A. Objective features of subjective cognitive decline in a United States national database. Alzheimers Dement, 13:1337-1344, Published 2017, PMC5712483.

210.   Kiely T, Moore C, Lee E, Shaughnessy A, Atri A, Marreiro C. The Contribution of Neuropsychological Performance, Behavioral and Functional Measures in High- & Low-likelihood Alzheimer's Disease Profiles. International Neuropsychological Society 45th Annual Meeting, 223, Published 2017. (Abstract)

211.   Kim J, Fischer CE, Schweizer TA, Munoz DG. Gender and pathology-specific effect of Apolipoprotein E genotype on psychosis in Alzheimer's disease. Curr Alzheimer Res, 14:834-840, Published 2017, PMC5837801.

212.   Kim J, Qian W, Fischer CE, Schweizer TA, Munoz DG. APOE ε4 Promotes Psychosis in Female Alzheimer's Disease Patients in Association with Lewy Bodies. Alzheimers Dement, 13:P1388-P1389, Published 2017. (Abstract)

213.   Kim J, Schweizer TA, Fischer CE, Munoz DG. The role of cerebrovascular disease on cognitive and functional status and psychosis in severe Alzheimer's disease. J Alzheimers Dis, 55:381-389, Published 2017, PMC5115606.

214.   Krysinska K, Sachdev P, Breitner J, Kivipelto M, Kukull WA, Brodaty H. Dementia registries around the globe and their applications: A systematic review. Alzheimers Dement, 9:1031-1047, Published 2017, PMC in process.

215.   Lange C, Suppa P, Maurer A, Ritter K, Pietrzyk U, Steinhagen-Thiessen E, Fiebach JB, Spies L, Buchert R. Mental speed is associated with the shape irregularity of white matter MRI hyperintensity load. Brain Imaging Behav, 11:1720-1730, Published 2017, PMC5843991.

216.   Leoutsakos JM. Trajectories of NPS in Pre-clinical NACC (National Alzheimer Coordinating Center) Participants and Conversion to MCI and Dementia. AAIC 2017, Accepted 2017. (Abstract)

217.   Lerner AJ, Lissemore FM, Luo EF, Miller R. Alcohol abuse and Neuropsychiatric Inventory behavioral symptoms in the NACC database. Alzheimers Dement, 13:P1225-P1226, Published 2017. (Abstract)

218.   Li X. A semiparametric method to estimate cognitive decline in dementia. IIE transactions in Healthcare Systems Engineering, Submitted 2017.

219.   Liu L. Effect of APOE Genotype on Alzheimer's Disease Diminishes in Octogenarians. 2018 Arizona Alzheimer's Consortium Retreat, Submitted 2017. (Abstract)

220.   LoBue C, Wadsworth H, Wilmoth K, Clem M, Hart J, Womack KB, Didehbani N, Lacritz LH, Rossetti HC, Munro C, Cullum CM. Traumatic Brain Injury History is Associated with Earlier Age of Onset of Alzheimer Disease. Clin Neuropsychol, 31:85-98, Published 2017, PMC5224912.

221.   Mattos M, Snitz BE, Lingler JH, Burke LE, Novosel LM, Sereika SM. Older Rural- and Urban-Dwelling Appalachian Adults with Mild Cognitive Impairment. J Rural Health, 33:208-216, Published 2017, PMC5303187.

222.   McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda JE, El-Agnaf O, Feldman H, Ferman TJ, Ffytche D, Fujishiro H, Galasko D, Goldman JG, Gomperts SN, Graff-Radford NR, Honig LS, Iranzo A, Kantarci K, Kaufer D, Kukull WA, Lee VMY, Leverenz JB, Lewis S, Lippa C, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O'Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka K. Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium. Neurology, 1:88-100, Published 2017, PMC5496518.

223.   McKenzie AT, Moyon S, Wang M, Katsyv I, Song WM, Zhou X, Dammer EB, Duong DM, Aaker J, Zhao Y, Beckmann N, Wang P, Zhu J, Lah JJ, Seyfried NT, Levey AI, Katsel P, Haroutunian V, Schadt EE, Popko B, Casaccia P, Zhang B. Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease. Mol Neurodegener, 1:82, Published 2017, PMC5674813.

224.   Medina LD. Hippocampal Volume is Related to Cognitive Function in Non-Hispanics but not in Hispanics in a Case-Control Matched Sample. Forty Fifth Annual INS Meeting, 23:139, Published 2017. (Abstract)

225.   Mez J, Chung J, Jun G, Kriegel J, Bourlas AP, Sherva R, Logue MW, Barnes LL, Bennett DA, Buxbaum JD, Byrdi GS, Crane PK, Ertekin-Taner N, Evans D, Fallin MD, Foroud T, Goate A, Graff-Radford NR, Hall KS, Kamboh MI, Kukull WA, Larson EB, Manly JJ, Alzheimer Disease Genetics Consortium, Haines JL, Mayeux R, Pericak-Vancet MA, Schellenberg GD, Lunetta KL, Farrer LA. Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans. Alzheimers Dement, 13:119-129, Published 2017, PMC5318231.

226.   Michaud TL, Su D, Siahpush M, Murman DL. The Risk of Incident Mild Cognitive Impairment and Progression to Dementia Considering Mild Cognitive Impairment Subtypes. Dement Geriatr Cogn Dis Extra, 1:15-29, Published 2017, PMC5346939.

227.   Mioshi E, Flanagan E, Knopman D. Detecting clinical change with the CDR-FTLD: differences between FTLD and AD dementia. Int J Geriatr Psychiatry, 32:977-982, Published 2017, PMC5274594.

228.   Mlynarski EE, Tang M, Amlie-Wolf A, Qu L, Kuzma A, Cantwell L, Ringman JM, Schellenberg GD, Wang LS. Ambidexterity and Alzheimer's disease risk. ASHG 2017, Submitted 2017. (Abstract)

229.   Moga DC, Abner E, Wu Q, Jicha G. Bladder Antimuscarinics and Cognitive Decline in Elderly Patients Enrolled in the National Alzheimer's Coordinating Center Cohort. Alzheimers Dement (N Y), 1:139-148, Published 2017, PMC5408467.

230.   Moga DC, Taipale H, Tolppanen AM, Tanskanen A, Tiihonen J, Hartikainen S, Jicha G, Gnjidic D. A Comparison of Sex Differences in Psychotropic Medication Use in Older People with Alzheimer's Disease in the US and Finland. Drugs Aging, 34:55-65, Published 2017, PMC5253689.

231.   Moheb N, Mendez MF, Kremen S, Teng E. Executive Dysfunction and Behavioral Symptoms Are Associated with Deficits in Instrumental Activities of Daily Living in Frontotemporal Dementia. 10th International Conference on Frontotemporal Dementias, 86:1526-632X, Published 2017. (Abstract)

232.   Moheb N, Mendez MF, Kremen SA, Teng E. Executive Dysfunction and Behavioral Symptoms Are Associated with Deficits in Instrumental Activities of Daily Living in Frontotemporal Dementia. Dement Geriatr Cogn Disord, 43:89-99, Published 2017, PMC5300022.

233.   Monsell SE, Mock C, Fardo DW, Bertelsen S, Cairns NJ, Roe CM, Ellingson S, Morris JC, Goate AM, Kukull WA. Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology. Alzheimer Dis Assoc Disord, 31:232-238, Published 2017, PMC5432419.

234.   Montgomery V, Harris K, Stabler A, Lu LH. Effects Of Delay Duration On The WMS Logical Memory Performance Of Older Adults With Probable Alzheimer's Dementia, Probable Vascular Dementia, and Normal Cognition. Arch Clin Neuropsychol, 3:375-380, Published 2017, PMC5400025.

235.   Montgomery V, Spencer RJ, Bieliauskas LA. Complaints of difficulties handling business affairs is predictive of poorer cognitive performances in a well-educated sample. INS Mid-Year Meeting, Accepted 2017. (Abstract)

236.   Moore C, Kiely T, Marreiro C, Lee A, Shaughnessy L, Atri A. Diagnostic Accuracy of Pathologically Confirmed AD in the NACC UDS. International Neuropsychological Society 45th Annual Meeting, 226-227, Published 2017. (Abstract)

237.   Moulder KL, Besser LM, Beekly D, Monsell SE, Blennow K, Kukull W, Morris JC. Factors Influencing Successful Lumbar Puncture in Alzheimer Research. Alzheimer Dis Assoc Disord, 31:287-294, Published 2017, PMC5699954.

238.   Myrum C, Nikolaienko O, Bramham CR, Haavik J, Zayats T, ADGC Collaborators. Implication of the APP Gene in Intellectual Abilities. J Alzheimers Dis, 14:834-840, Published 2017, PMC5837801.

239.   Neu SC, Pa J, Kukull W, Beekly D, Kusma A, Gangadharan P, Wang LS, Romero K, Arneric SP, Redolfi A, Orlandi D, Frisoni GB, Au R, Devine S, Auerbach S, Espinosa A, Boada M, Riuiz A, Johnson SC, Koscik R, Wang JJ, Hsu WC, Chen YL, Toga AW. Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis. JAMA Neurol, 74:1178-1189, Published 2017, PMC5759346.

240.   Oh G, Abner E, Moga D. Utilization Patterns and Predictors of Opioid Use in Persons with Dementia. 33rd International Conference on Pharmacoepidemiology Therapeutic Risk Management, Accepted 2017. (Abstract)

241.   Pa J, Hobel Z, Eusebio AC, Brinton RD, Mack W, Toga AW, Alzheimer's Disease Neuroimaging Initiative (ADNI). Association between gender and statin use on Alzheimer's disease biomarkers. Lancet, Submitted 2017.

242.   Pandya SY, Lacritz LH, Weiner MF, Deschner M, Woon FL. Predictors of Reversion from Mild Cognitive Impairment to Normal Cognition. Dement Geriatr Cogn Disord, 43:204-214, Published 2017, PMC5495561.

243.   Qian J, Hyman BT, Betensky RA. Neurofibrillary Tangle Stage and the Rate of Progression of Alzheimer Symptoms: Modeling Using an Autopsy Cohort and Application to Clinical Trial Design. JAMA Neurol, 74:540-548, Published 2017, PMC5547572.

244.   Qian J, Wolters F, Beiser A, Haan M, Ikram MA, Karlawash J, Langbaum JB, Neuhaus J, Reiman E, Roberts J, Seshadri S, Tariot PN, Wood BM, Betensky RA, Blacker D. APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts. PLoS Med, 14:e1002254, Published 2017, PMC5360223.

245.   Qian W, Fischer CE, Schweitzer TA, Munoz DG. Determining the Impact of Psychosis on Rates of False Positive and False Negative Diagnosis in Alzheimer's Disease. Am J Geriatr Psychiatry, 25(3) Supplement 1:S126, Published 2017. (Abstract)

246.   Qian W, Schweizer T, Munoz D, Fischer C. Relationship between APOE e4 and cognitive and functional outcomes in Alzheimer's disease patients with psychosis. Am J Geriatr Psychiatry, Supplement 1:S127, Published 2017. (Abstract)

247.   Qiu RG, Qiu JL, Badr Y. Predictive Modeling of the Severity/Progression of Alzheimer's Diseases. IEEE International Conference on Grey Systems and Intelligent Services, Accepted 2017. (Abstract)

248.   Rascovsky k, Teylan ME, McMillan CT, Besser L, Kukull W, Grossman M. Neuropsychiatric symptoms in Latino patients with Alzheimer's disease: an analysis of the NACC database. Neurology, 88:P4.084, Published 2017. (Abstract)

249.   Rehker J, Rodhe J, Nesbitt RR, Boyle EA, Martin BK, Lord J, Karaca I, Naj A, Jessen F, Helisalmi S, Soininen H, Hiltunen M, Ramirez A, Scherer M, Farrer LA, Haines JL, Pericak-Vance MA, Raskind WH, Cruchaga C, Schellenberg GD, Joseph B, Brkanac Z. Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants. PLoS One, 12:e0185777, Published 2017, PMC5630132.

250.   Rindge M, Moncrief G, Daniel M. Neuropsychological and Psychological Predictors of Conversion from Mild Cognitive Impairment to Alzheimer's Dementia. Arch Clin Neuropsychol, 32:667-765, Published 2017. (Abstract)

251.   Ritter AR, Leger GC, Miller JB, Banks SJ. Neuropsychological testing in pathologically verified Alzheimer's disease and frontotemporal dementia: how well do the Uniform Data Set measures differentiate between diseases?. Alzheimer Dis Assoc Disord, 31:187-191, Published 2017, PMC5479762.

252.   Rosenberg PB, Han D, Leoutsakos JM, Rattinger GB, Stuart EA, Oh ES, Lyketsos CG. Psychotropic medication exposure and cognitive, functional, and neuropsychiatric outcomes in Alzheimer's Disease (AD). J Am Geriatr Soc, Revision 2017.

253.   Sandoval K, Loux T, Wang J, Schootman M. Differential Impact of Proton Pump Inhibitors on Probable Alzheimer's Disease Diagnosis in Patients with Normal Cognition versus Mild Cognitive Impairment. TBD, Revision 2017.

254.   Sano M, Zhu CW, Grossman H, Schimming C. Longitudinal cognitive profiles in diabetes: Results from the National Alzheimer's Coordinating Center's Uniform Data. J Am Geriatr Soc, 65:2198-2204, Published 2017, PMC5641239.

255.   Schaffert J, LoBue C, Nguyen T, Lacritz L, Womack K, Hart J, Cullum C. Risk factors for earlier age at onset of dementia with Lewy bodies. Arch Clin Neuropsychol, 32:667-765, Published 2017. (Abstract)

256.   Schaffert J, Lobue C, White C, Chiang H, Dieppa M, Lacritz L, Didehbani N, Hart J, Cullum C. Traumatic brain injury history is associated with an earlier age of dementia onset in autopsy-confirmed Alzheimer disease. Arch Clin Neuropsychol, 32:656-666, Published 2017. (Abstract)

257.   Schwabe-Fry K, Bollenbeck M, Teylan M, Beekly D, Thomas G, Hubbard J, Jacka M, Wu J, Besser L, Kukull WA. The National Alzheimer's Coordinating Center: Querying the Database and Requesting Data. Alzheimers Dement, 13:P158, Published 2017. (Abstract)

258.   Sennik S, Schweizer TA, Fischer CE, Munoz DG. Risk Factors and Pathological Substrates Associated with Agitatioggression in Alzheimer's Disease: A Preliminary Study using NACC Data. J Alzheimers Dis, 4:1519-1528, Published 2017, PMC5607738.

259.   Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Partch A, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi S-H, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sanchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead PL, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Longstreth Jr WT, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Sánchez-Juan P, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Himali JJ, Keene CD, Tschanz J, Fitzpatrick AL, Kukull WA, Norton M, Aspelund T, Larson EB, Munger R, Rotter JI, Lipton RB, Bullido MJ, Hofman A, Montine TJ, Coto E, Boerwinkle E, Petersen RC, Alvarez V, Rivadeneira F, Reiman EM, Gallo M, O'Donnell CJ, Reisch JS, Bruni AC, Royall DR, Dichgans M, Sano M, Galimberti D, St George-Hyslop P, Scarpini E, Tsuang DW, Mancuso M, Wendland JR, Bonuccelli U, Winslow AR, Daniele A, Wu C-K, GERAD/PERADES, CHARGE, ADGC, EADI, Peters O, Nacmias B, Riemenschneider M, Heun R, Brayne C, Rubinsztein DC, Bras J, Guerreiro R, Hardy J, Al-Chalabi A, Shaw CE, Collinge J, Mann D, Tsolaki M, Clarimón J, Sussams R, Lovestone S, O'Donovan MC, Owen MJ, Behrens TW, Mead S, Goate AM, Uitterlinden AG, Holmes C, Cruchaga C, Ingelsson M, Bennett DA, Powell J, Golde TE, Graff C, De Jager PL,. Rare coding variants in PLCG2, ABI3 and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nat Gent, 49:1373-1384, Published 2017, PMC5669039.

260.   Sofko C, Hill B, Burton J. New approaches in the calculation of cognitive intra-individual variability: Introduction of a geometric measure. TBD, Revision 2017.

261.   Sofko C. Neuropsychological Intra-Individual Variability and Resilient Cognitive Aging. University of South Alabama, Defended 2017.

262.   Spencer BE, Digma LA, Brewer JB. Medial temporal atrophy and its association with amyloid status and neuropathology. Alzheimers Dement, 13:P1126, Published 2017. (Abstract)

263.   Spiegel R, Monsch AU, Berres M. Validation Studies with the Placebo Group Simulation Approach (PGSA) in Different MCI Datasets. Alzheimers Dement, 13:P1141, Published 2017. (Abstract)

264.   Sposato LA, Vargas ER, Riccio PM, Toledo JB, Trojanowski JQ, Kukull WA, Cipriano LE, Nucera A, Whitehead SN, Hachinski V. Milder Alzheimer's disease pathology in heart failure and atrial fibrillation. Alzheimers Dement, 13:770-777, Published 2017, PMC5592781.

265.   Steele NZ, Carr JS, Bonham LW, Geier EG, Damotte V, Miller ZA, Desikan RS, Boehme KL, Mukherjee S, Crane PK, Kauwe JS, Kramer JH, Miller BL, Coppola G, Hollenbach JA, Huang Y, Yokoyama JS, ADGC Collaborators. Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study. PLoS Med, 14:e1002272, Published 2017, PMC5369701.

266.   Stickel A, Ryan L. Associations between cardiovascular risk factors and cognition in late middle age and older Hispanics compared to non-Hispanic Whites. Arizona Alzheimer's Consortium, Accepted 2017. (Abstract)

267.   Teylan M, Besser LM, Brenowitz WD, Wilk S, Barlow N, Kukull WA. Associations of neuropathology and apolipoprotein E genotype with dementia in the Oldest Old compared to younger-old age groups. Alzheimers Dement, 13:P1189, Published 2017. (Abstract)

268.   Ting SKS, Hao Y, Chia PSP, Tan EK, Hameed S. Clinicopathological correlation of psychosis and brain vascular changes in Alzheimer's disease. Sci Rep, 6:20858, Published 2017, PMC4751434.

269.   Tripodis Y, Alosco ML, Zirogiannis N, Gavett BE, Chaisson C, Martin B, McClean MD, Mez J, Kowall N, Stern RA. The Effect of Traumatic Brain Injury History with Loss of Consciousness on Rate of Cognitive Decline Among Older Adults with Normal Cognition and Alzheimer's Disease Dementia. J Alzheimers Dis, 59:251-263, Published 2017, PMC5614490.

270.   Verney SP, Jensen PN, Nelson L, Omidpanah A, Cholertin B, Avila J, Montine TJ, Monsell SE, Buchwald D. A Profile of American Indians and Alaska Natives in the Alzheimer Disease Centers. Alzheimer Dis Assoc Disord, Submitted 2017.

271.   Vikas, V. Evaluation of Neuropsychological Tests in Classification of Alzheimer's Disease. 2nd International Conference on Advanced Computing and Intelligent Engineering (ICACIE), Accepted 2017. (Abstract)

272.   Vitale JG, Zachar R, Grego A, Golden CJ. Working Towards a Neuropsychological Profile for the Major Sleep Disorders. National Academy of Neuropsychology, Accepted 2017. (Abstract)

273.   Wang L, Zhou XH, Richardson TS. Identification and estimation of causal effects with outcomes truncated by death. Biometrika, 104:597-612, Published 2017, PMC5793679.

274.   Wang T, Qiu RG, Yu M. Deep Learning Approach to Modeling the Progression of Alzheimer's Disease. Manage Sci, Submitted 2017.

275.   Werry A, Daniel M, Bergstrom B. Differences in Clinical Classification Using Combined Ethnic and Ethnic Specific Norms in Older Adults. Arch Clin Neuropsychol, 32:673, Published 2017. (Abstract)

276.   Werry A, Daniel M. Normal Neuropsychological Test Performance for English Speaking Hispanic and Matched White Older Adults. Arch Clin Neuropsychol, 32:674, Published 2017. (Abstract)

277.   Werry A, Daniel M. Normal Neuropsychological Test Performance for Spanish Speaking Hispanic and Matched White Older Adults. Arch Clin Neuropsychol, 32:675, Published 2017. (Abstract)

278.   Zhan L, Guo L, Jin Y, Marzofka E, Lamar M, Leow A, Thompson P. Brain Differential Structural Connectome. Annual Meeting of the Organization for Human Brain Mapping, Accepted 2017. (Abstract)

279.   Zhu CW, Grossman H, Schimming C, Sano M. Non-Amnestic Deficit Characterizes the Cognitive Profile in Diabetes: Results from National Alzheimer's Coordinating Center's Uniform Data Set (NACC UDS). Alzheimers Dement, 13:P484-P485, Published 2017. (Abstract)

 
         2016
280.   Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Renteria ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivieres S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beiser A, Bernard M, Bis JC, Blanken LM, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chauhan G, Chen Q, Ching CR, Cuellar-Partida G, Braber AD, Doan NT, Ehrlich S, Filippi I, Ge T, Giddaluru S, Goldman AL, Gottesman RF, Greven CU, Grimm O, Griswold ME, Guadalupe T, Hass J, Haukvik UK, Hilal S, Hofer E, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liao J, Liewald DC, Lopez LM, Luciano M, Macare C, Marquand A, Matarin M, Mather KA, Mattheisen M, Mazoyer B, McKay DR, McWhirter R, Milaneschi Y, Mirza-Schreiber N, Muetzel RL, Maniega SM, Nho K, Nugent AC, Loohuis LM, Oosterlaan J, Papmeyer M, Pappa I, Pirpamer L, Pudas S, Putz B, Rajan KB, Ramasamy A, Richards JS, Risacher SL, Roiz-Santianez R, Rommelse N, Rose EJ, Royle NA, Rundek T, Samann PG, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Thomson R, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Vaidya D, Van der Grond J, Van der Meer D, Van Donkelaar MM, Van Eijk KR, Van Erp TG, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Woldehawariat G, Wolf C, Wolfers T, Xu B, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Aggarwal NT, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Chen C, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Geus EJ, De Jager PL, de Zubicaray GI, Delanty N, Depondt C, DeStefano AL, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Erk S, Espeseth T, Evans DA, Fedko IO, Fernandez G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, Goring HH, Grabe HJ, Green RC, Gruber O, Gudnason V, Guelfi S, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboe. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nat Neurosci, 12:1569-1582, Published 2016, PMC5227112.

281.   Ahmed M, Besser L, Galasko D, Salmon D, Kukull W. Traumatic Brain Injury (TBI) and Dementia Progression. Alzheimers Dement, 12:P703-P704, Published 2016. (Abstract)

282.   Armstrong JJ, Godin J, Wallace LMK, Andrew MK, Rockwood K. Frailty Impacts the Relationship Between Neuropathology and Dementia Disease Expression. Alzheimers Dement, 12:P559, Published 2016. (Abstract)

283.   Barban N, Jansen R, de Vlaming R, Vaez A, Mandemakers JJ, Tropf FC, Shen X, Wilson JF, Chasman DI, Nolte IM, Tragante V, van der Laan SW, Perry JR, Kong A, Consortium B, Ahluwalia TS, Albrecht E, Yerges-Armstrong L, Atzmon G, Auro K, Ayers K, Bakshi A, Ben-Avraham D, Berger K, Bergman A, Bertram L, Bielak LF, Bjornsdottir G, Bonder MJ, Broer L, Bui M, Barbieri C, Cavadino A, Chavarro JE, Turman C, Concas MP, Cordell HJ, Davies G, Eibich P, Eriksson N, Esko T, Eriksson J, Falahi F, Felix JF, Fontana MA, Franke L, Gandin I, Gaskins AJ, Gieger C, Gunderson EP, Guo X, Hayward C, He C, Hofer E, Huang H, Joshi PK, Kanoni S, Karlsson R, Kiechl S, Kifley A, Kluttig A, Kraft P, Lagou V, Lecoeur C, Lahti J, Li-Gao R, Lind PA, Liu T, Makalic E, Mamasoula C, Matteson L, Mbarek H, McArdle PF, McMahon G, Meddens SF, Mihailov E, Miller M, Missmer SA, Monnereau C, van der Most PJ, Myhre R, Nalls MA, Nutile T, Kalafati IP, Porcu E, Prokopenko I, Rajan KB, Rich-Edwards J, Rietveld CA, Robino A, Rose LM, Rueedi R, Ryan KA, Saba Y, Schmidt D, Smith JA, Stolk L, Streeten E, Tonjes A, Thorleifsson G, Ulivi S, Wedenoja J, Wellmann J, Willeit P, Yao J, Yengo L, Zhao JH, Zhao W, Zhernakova DV, Amin N, Andrews H, Balkau B, Barzilai N, Bergmann S, Biino G, Bisgaard H, Bonnelykke K, Boomsma DI, Buring JE, Campbell H, Cappellani S, Ciullo M, Cox SR, Cucca F, Toniolo D, Davey-Smith G, Deary IJ, Dedoussis G, Deloukas P, van Duijn CM, de Geus EJ, Eriksson JG, Evans DA, Faul JD, Sala CF, Froguel P, Gasparini P, Girotto G, Grabe HJ, Greiser KH, Groenen PJ, de Haan HG, Haerting J, Harris TB, Heath AC, Heikkila K, Hofman A, Homuth G, Holliday EG, Hopper J, Hypponen E, Jacobsson B, Jaddoe VW, Johannesson M, Jugessur A, Kahonen M, Kajantie E, Kardia SL, Keavney B, Kolcic I, Koponen P, Kovacs P, Kronenberg F, Kutalik Z, La Bianca M, Lachance G, Iacono WG, Lai S, Lehtimaki T, Liewald DC, LifeLines Cohort S, Lindgren CM, Liu Y, Luben R, Lucht M, Luoto R, Magnus P, Magnusson PK, Martin NG, McGue M, McQuillan R, Medland SE, Meisinger C, Mellstrom D, Metspalu A, Traglia M, Milani L, Mitchell P, Montgomery GW, Mook-Kanamori D, de Mutsert R, Nohr EA, Ohlsson C, Olsen J, Ong KK, Paternoster L, Pattie A, Penninx BW, Perola M, Peyser PA, Pirastu M, Polasek O, Power C, Kaprio J, Raffel LJ, Raikkonen K, Raitakari O, Ridker PM, Ring SM, Roll K, Rudan I, Ruggiero D, Rujescu D, Salomaa V, Schlessinger D, Schmidt H, Schmidt R, Schupf N, Smit J, Sorice R, Spector TD, Starr JM, Stockl D, Strauch K, Stumvoll M, S. Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Nat Genet, 12:1462-1472, Published 2016, PMC5695684.

284.   Besser LM, SE Litvan I, Monsell SE, Mock C, Weintraub S, Zhou XH, Kukull W. Mild cognitive impairment in Parkinson's disease versus Alzheimer's disease. Parkinsonism Relat Disord, 27:54-60, Published 2016, PMC4887313.

285.   Besser LM, Alosco ML, Gomez LR, Zhou X, McKee AC, Stern RA, Gunstad J, Schneider JA, Chui H, Kukull WA. Late-Life Vascular Risk Factors and Alzheimer Disease Neuropathology in Individuals with Normal Cognition. J Neuropathol Exp Neurol, 75:955-962, Published 2016, PMC5029440.

286.   Bianco K. Risk of Alzheimer's Disease Among Older Hispanic/Latinos with Diabetes. Walden University, Defended 2016.

287.   Bonham LW, Geier EG, Fan CC, Leong JK, Besser L, Kukull WA, Kornak J, Andreassen OA, Schellenberg GD, Rosen HJ, Dillon WP, Hess CP, Miller BL, Dale AM, Desikan RS, Yokoyama JS. Age-dependent effects of APOE ε4 in preclinical Alzheimer's disease. Ann Clin Transl Neurol, 3:668-677, Published 2016, PMC5018579.

288.   Brenowitz WD, Hubbard RA, Keene D, Hawes SE, Longstreth WT, Jr., Kukull WA. Clinical progression in mixed neuropathologies: testing interactions of Lewy bodies and vascular brain injury with Alzheimer's disease neuropathologic change. Alzheimers Dement, 12:P736-P737, Published 2016. (Abstract)

289.   Buckles V, Xiong C, Weng HB, Bateman R, Chhatwal JP, Ghetti B, Goate A, Graff-Radford NR, Hassenstab J, Mayeux R, Masters C, McDade E, Moulder KL, Paumier K, Ringman JM, Salloway S, Schofield PW, Morris JC, the Dominantly Inherited Alzheimer Network. The Dian-NACC UDS Comparison Study: Rates of Cognitive Decline. Alzheimers Dement, 12:P309, Published 2016. (Abstract)

290.   Burke SL, Maramaldi P, Cadet T, Kukull W. Neuropsychiatric symptoms and Apolipoprotein E: Associations with eventual Alzheimer's disease development. Arch Gerontol Geriatr, 65:231-238, Published 2016, PMC5029123.

291.   Callahan BL, Duchesnea S, Black SE. Pathological correlates associated with ante-mortem neuropsychological performance in Alzheimer's disease. Alzheimers Dement, 12(S7):560-561, Published 2016. (Abstract)

292.   Chapman KR, Bing-Canar H, Alosco ML, Steinberg EG, Martin, B, Chaisson C, Kowall N, Triposdis Y, Stern RA. Mini Mental State Examination and logical Memory scores for entry into Alzheimer's disease trials. Alzheimers Res Ther, 8:9, Published 2016, PMC4762168.

293.   Chen W, Albert MA, Han DF, Lyketsos CG, Rosenberg PB. Neuropathological correlates of apathy in Alzheimer's Disease. Am J Geriatr Psychiatry, Revision 2016.

294.   Chi CL, Zeng W, Oh W, Borson S. A Translational Research Strategy to Individualize Prediction of Long-Term Cognitive Trajectory. Alzheimers Dement, 12:P847, Published 2016. (Abstract)

295.   Davis M, O'Connell T, Johnson S, Cline S, Merikle E, Martenyi F, Simpson K. Modeling the Benefits of Delayed Onset of Mild Cognitive Impairment due to Alzheimer's Disease in the United States. SMDM 38th Annual North American Meeting, Accepted 2016. (Abstract)

296.   Day G, Musiek E, Roe C, Norton J, Goate A, Cruchaga C, Morris J. The clinical phenotype of late-onset autosomal dominant Alzheimer disease due to a PSEN1 mutation resembles sporadic Alzheimer disease: A single-family case-control study. Neurology, 86:Supplement P2.2, Published 2016. (Abstract)

297.   Day GS, Musiek ES, Roe CM, Norton J, Goate AM, Cruchaga C, Cairns NJ, Morris JC. Phenotypic Similarities Between Late-Onset Autosomal Dominant and Sporadic Alzheimer Disease: A Single-Family Case-Control Study. Alzheimers Dement, 12:P698-P699, Published 2016. (Abstract)

298.   Devanand DP, Liu X, Brown P. Impact of Functional Deficits in Mild Cognitive Impairment: A Clinical Algorithm to Predict Progression to Dementia. Alzheimers Dement, 12:P393-P394, Published 2016. (Abstract)

299.   Diah K, Capp K, Grodner K, Lavallee K, Stripling A. Neuropsychiatric Presentations of Alzheimer's disease that Impact Cognitive and Daily Life Functioning. Gerontological Society of America Annual Scientific Meeting, Accepted 2016. (Abstract)

300.   Ebbert MT, Boehme KL, Wadsworth ME, Staley LA, Mukherjee S, Crane PK, Ridge PG, Kauwe JS, ADGC Collaborators. Interaction between variants in CLU and MS4A4E modulates Alzheimer's disease risk. Alzheimers Dement, 12:121-129, Published 2016, PMC4744542.

301.   Ebbert MT, Staley LA, Parker J, Parker S, Bailey M, Ridge PG, Goate AM, Kauwe JSADGC Collaborators. Variants in CCL16 are associated with blood plasma and cerebrospinal fluid CCL16 protein levels. BMC Genomics, 17 Suppl 3:437, Published 2016, PMC4943476.

302.   Filshtein T, Beckett LA, Godwin H, Hinton L, Xiong GL. Incident Antipsychotic Use in a Diverse Population with Dementia. J Am Geriatr Soc, 64:e44-46, Published 2016, PMC5026861.

303.   Forrester SN, Gallo JJ, Smith GS, Leoutsakos JS. Patterns of Neuropsychiatric Symptoms in Mild Cognitive Impairment and Risk of Dementia. Am J Geriatr Psychiatry, 24:117-125, Published 2016, PMC4646727.

304.   Fryland T, Christensen JH, Pallesen J, Mattheisen M, Palmfeldt J, Bak M, Grove J, Demontis D, Blechingberg J, Ooi HS, Nyegaard M, Hauberg ME, Tommerup N, Gregersen N, Mors O, Corydon TJ, Nielsen AL, Borglum AD, ADGC Collaborators. Identification of the BRD1 interaction network and its impact on mental disorder risk. Genome Med, 8:53, Published 2016, PMC4855718.

305.   Graff-Radford NR, Besser LM, Crook JE, Kukull WA, Dickson DW. Neuropathologic differences by race from the National Alzheimer's Coordinating Center. Alzheimers Dement, 12:669-677, Published 2016, PMC4903907.

306.   Graff-Radford NR, Besser L, Crook JE, Kukull W, Dickson DW. African American Brain Autopsies from the National Alzheimer's Coordinating Center. Alzheimers Dement, 12:P557-P558, Published 2016. (Abstract)

307.   Green AR, Oh E, Hilson L, Tian J, Boyd. Anticholinergic Burden in Older Adults with Mild Cognitive Impairment. J Am Geriatr, 64:e313-e314, Published 2016.

308.   Green C, Zhang S. Predicting the progression of Alzheimer's disease dementia: A multidomain health policy model. Alzheimers Dement, 12:776-785, Published 2016, PMC5104191.

309.   Grossman H, Zhu C, Sano M. Role of Apathy in Functional Decline in Alzheimer's Disease. International Psychogeriatric Association (IPA) International Congress, San Francisco, California, Accepted 2016. (Abstract)

310.   Hohman TJ, Bush WS, Chibnik L, De Jaeger PL, Bennett DA, Schneider JA, Haines JL, Thornton-Wells TA. Genetic Interactions Predict the Presence of Alzheimer's Disease Neuropathology at Autopsy. Alzheimers Dement, Submitted 2016.

311.   Hohman TJ, Bush WS, Jiang L, Brown-Gentry KD, Torstenson ES, Dudek SM, Mukherjee S, Naj A, Kunkle BW, Ritchie MD, Martin ER, Schellenberg GD, Mayeux R, Farrer LA, Pericak-Vance MA, Haines JL, Thornton-Wells TA, ADGC Collaborators. Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium. Neurobiol Aging, 38:141-150, Published 2016, PMC4735733.

312.   Hohman TJ, Cooke-Bailey JN, Reitz C, Jun G, Naj A, Beecham GW, Liu Z, Carney RM, Vance JM, Cuccaro ML, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue MW, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith P, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hardy J, Hendrie HC, Hall KS, Goate AM, Lang R, Byrd GS, Kukull WA, Foroud TM, Farrer LA, Martin ER, Pericak-Vance MA, Schellenberg GD, Mayeux R, Haines JL, Thornton-Wells TA, ADGC Collaborators. Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk. Alzheimers Dement, 12:233-243, Published 2016, PMC4681680.

313.   Hu T, Burke SL, Schuldiner KL, Burgess A. A longitudinal examination of prescription drug usage associated with progression through stages of cognitive impairment. Drugs Aging, Submitted 2016.

314.   Ighodaro ET, Abner EL, Monsell SE, Kukull WA, Neltner JH, Smith V, Fardo D, Nelson PT. Decoding Subtypes and Risk Factors of a Common Vascular Pathology: Brain Arteriolosclerosis. 2016 American Association of Neuropathologists Annual Conference, Submitted 2016. (Abstract)

315.   Irwin D, Grossman M, Weintraub D, Hurtig H, Duda J, Lopez O, Kofler J, Nelson P, Woltjer R, Quinn J, Kaye J, Leverenz J, Tsuang D, Longfellow K, Kukull W, Keene CD, Montine T, Zabetian C, Trojanowski J. Neuropathological Influences on the Clinical Phenotype of Synucleinopathies. Neurology, 86:P6.225, Published 2016. (Abstract)

316.   Jakobsdottir J, van der Lee SJ, Bis JC, Chouraki V, Li-Kroeger D, Yamamoto S, Grove ML, Naj A, Vronskaya M, Salazar JL, DeStefano AL, Brody JA, Smith AV, Amin N, Sims R, Ibrahim-Verbaas CA, Choi SH, Satizabal CL, Lopez OL, Beiser A, Ikram MA, Garcia ME, Hayward C, Varga TV, Ripatti S, Franks PW, Hallmans G, Rolandsson O, Jansson JH, Porteous DJ, Salomaa V, Eiriksdottir G, Rice KM, Bellen HJ, Levy D, Uitterlinden AG, Emilsson V, Rotter JI, Aspelund T, O'Donnell CJ, Fitzpatrick AL, Launer LJ, Hofman A, Wang LS, Williams J, Schellenberg GD, Boerwinkle E, Psaty BM, Seshadri S, Shulman JM, Gudnason V, van Duijn CM, ADGC Collaborators. Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease. PLoS Genet, 12:e1006327, Published 2016, PMC5072721.

317.   Jefferson-George K, Lee E, Wolk D, McMillan CT. Cognitive Reserve in Primary Age-Related Tauopathy. Neurology, 86:P6.205, Published 2016. (Abstract)

318.   Jeffrey M, Capp K, Grodner K, Craddock TJA. Pharmacological Interventions for Parkinsonian and Depressive Symptoms. 36th annual meeting of the National Academy of Neuropsychology, Seattle, WA, Accepted 2016. (Abstract)

319.   Jeffrey M, Capp K, Stripling A. Genetic Screening and Functional Assessment as Predictors in Cognitive Decline. APA, 30:775-776, Published 2016. (Abstract)

320.   Jeffrey M, Diah K, Capp K, Stripling A. The Geriatric Depression Scale- Short Form (GDS - SF): A model for African American populations. Gerontologist, 56:376, Published 2016. (Abstract)

321.   John SE, Gavett BE. Effectiveness and Unique Contribution of Neuropsychological Tests in the Differential Diagnosis of Dementia. International Neuropsychological Society, Boston, MA, Accepted 2016. (Abstract)

322.   John SE, Gurnani AS, Bussell C, Saurman JL, Griffin JW, Gavett BE. The Effectiveness and Unique Contribution of Neuropsychological Tests and the δ Latent Phenotype in the Differential Diagnosis of Dementia in the Uniform Data Set. Neuropsychol, 30:946-960, Published 2016, PMC5130291.

323.   Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, Beecham GW, Smith AV, Chouraki V, Hamilton-Nelson KL, Ikram MA, Fievet N, Denning N, Martin ER, Schmidt H, Kamatani Y, Dunstan ML, Valladares O, Laza AR, Zelenika D, Ramirez A, Foroud TM, Choi SH, Boland A, Becker T, Kukull WA, van der Lee SJ, Pasquier F, Cruchaga C, Beekly D, Fitzpatrick AL, Hanon O, Gill M, Barber R, Gudnason V, Campion D, Love S, Bennett DA, Amin N, Berr C, Tsolaki M, Buxbaum JD, Lopez OL, Deramecourt V, Fox NC, Cantwell LB, Tarraga L, Dufouil C, Hardy J, Crane PK, Eiriksdottir G, Hannequin D, Clarke R, Evans D, Mosley TH, Jr., Letenneur L, Brayne C, Maier W, De Jager P, Emilsson V, Dartigues JF, Hampel H, Kamboh MI, de Bruijn RF, Tzourio C, Pastor P, Larson EB, Rotter JI, O'Donovan MC, Montine TJ, Nalls MA, Mead S, Reiman EM, Jonsson PV, Holmes C, St George-Hyslop PH, Boada M, Passmore P, Wendland JR, Schmidt R, Morgan K, Winslow AR, Powell JF, Carasquillo M, Younkin SG, Jakobsdottir J, Kauwe JS, Wilhelmsen KC, Rujescu D, Nothen MM, Hofman A, Jones L, Haines JL, Psaty BM, Van Broeckhoven C, Holmans P, Launer LJ, Mayeux R, Lathrop M, Goate AM, Escott-Price V, Seshadri S, Pericak-Vance MA, Amouyel P, Williams J, van Duijn CM, Schellenberg GD, Farrer LA. A novel Alzheimer disease locus located near the gene encoding tau protein. Mol Psychiatry, 21:108-117, Published 2016, PMC4573764.

324.   Kalapatapu RK, Delucchi KL, Wang S, Harbison J, Nelson EE, Kramer JH. Substance Use History in Behavioral-Variant Frontotemporal Dementia versus Primary Progressive Aphasia: A Baseline Analysis of a National Dataset. J Addict Dis, 35:36-41, Published 2016, PMC4720534.

325.   Karch CM, Ezerskiy LA, Bertelsen S, Goate AM, ADGC Collaborators. Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci. PLoS One, 11:e0148717, Published 2016, PMC4769299.

326.   Kaur A, Edland S, Guerry P. Utilizing MoCA-MIS scoring to evaluate episodic memory performance. 144th annual American Public Health Association Conference, Denver, CO, Accepted 2016. (Abstract)

327.   Kenna KP, van Doormaal PT, Dekker AM, Ticozzi N, Kenna BJ, Diekstra FP, van Rheenen W, van Eijk KR, Jones AR, Keagle P, Shatunov A, Sproviero W, Smith BN, van Es MA, Topp SD, Kenna A, Miller JW, Fallini C, Tiloca C, McLaughlin RL, Vance C, Troakes C, Colombrita C, Mora G, Calvo A, Verde F, Al-Sarraj S, King A, Calini D, de Belleroche J, Baas F, van der Kooi AJ, de Visser M, Ten Asbroek AL, Sapp PC, McKenna-Yasek D, Polak M, Asress S, Munoz-Blanco JL, Strom TM, Meitinger T, Morrison KE, Consortium S, Lauria G, Williams KL, Leigh PN, Nicholson GA, Blair IP, Leblond CS, Dion PA, Rouleau GA, Pall H, Shaw PJ, Turner MR, Talbot K, Taroni F, Boylan KB, Van Blitterswijk M, Rademakers R, Esteban-Perez J, Garcia-Redondo A, Van Damme P, Robberecht W, Chio A, Gellera C, Drepper C, Sendtner M, Ratti A, Glass JD, Mora JS, Basak NA, Hardiman O, Ludolph AC, Andersen PM, Weishaupt JH, Brown RH, Jr., Al-Chalabi A, Silani V, Shaw CE, van den Berg LH, Veldink JH, Landers JE, ADGC Collaborators. NEK1 variants confer susceptibility to amyotrophic lateral sclerosis. Nat Genet, 9:1037-42, Published 2016, PMC5560030.

328.   Ketlogetswe N, Wyman-Chick KA, Sperling SA, Manning CA. Judgment/problem-solving and neuropsychological test performance in non-demented older adults with HIV. International Neuropsychological Society Mid-Year Meeting, London, UK, Accepted 2016. (Abstract)

329.   Kim J, Fischer CE, Schweizer TA, Munoz DG. Impact of Hypertension on Delusions in Patients with Severe Alzheimer's disease. Alzheimers Dement, 12:P955, Published 2016. (Abstract)

330.   Kirson NY, Andrews JS, Shei A, King S, Schonfeld S, Birnbaum HG, Ball D, Kahle-Wrobleski K. Patient Characteristics and Outcomes Associated with Receiving an Earlier Versus Later Diagnosis of Probable Alzheimer's Disease: Evidence from the National Alzheimer's Coordinating Center Data. Alzheimers Dement, 12:P698, Published 2016. (Abstract)

331.   Lai D, Xu H, Koller D, Foroud T, Gao S. A Multivariate Finite Mixture Latent Trajectory Model with Application to Dementia Studies. J Appl Stat, 43:2503-2523, Published 2016, PMC5021196.

332.   Lange C, Suppa P, Maeurer A, Ritter K, Pietrzyk U, Steinhagen-Thiessen E, Fiebach J, Spies L, Buchert R. A novel marker for the characterization of the pattern of white matter MRI hyperintensities: the weighted confluency sum score. Alzheimers Dement, 12(7):P77-P78, Published 2016. (Abstract)

333.   Leoutsakos JM. Trajectories of NPS in Pre-clinical NACC (National Alzheimer Coordinating Center) Participants and Conversion to MCI and Dementia. International College of Geriatric Psychopharmacology, Accepted 2016. (Abstract)

334.   LoBue C, Denney D, Hynan LS, Rossetti HC, Lacritz LH, Hart J, Womack KB, Woon FL, Cullum CM. Self-Reported Traumatic Brain Injury and Mild Cognitive Impairment: Increased Risk and Earlier Age of Diagnosis. J Alzheimers Dis, 51:727-736, Published 2016, PMC4853649.

335.   LoBue C, Wilmoth K, Cullum CM, Rossetti HC, Lacritz LH, Hynan LS, Hart J, Womack KB. Traumatic brain injury history is associated with earlier age of onset of frontotemporal dementia. J Neurol Neurosurg Psychiatry, 87:817-820, Published 2016, PMC4835269.

336.   Lupton MK, Strike L, Hansell NK, Wen W, Mather KA, Armstrong NJ, Thalamuthu A, McMahon KL, de Zubicaray GI, Assareh AA, Simmons A, Proitsi P, Powell JF, Montgomery GW, Hibar DP, Westman E, Tsolaki M, Kloszewska I, Soininen H, Mecocci P, Velas B, Lovestone S, Brodaty H, Ames D, Trollor JN, Martin NG, Thompson PM, Sachdev PS, Wright MJ, ADGC Collaborators. The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume. Neurobiol Aging, 40:68-77, Published 2016, PMC4883003.

337.   Mattos M, Snitz B, Lingler JH, Burke LE, Novosel L, Sereika SM. Older Appalachian Adults with Mild Cognitive Impairment. National Rural Health Association Annual Conference, Minneapolis, MN, Accepted 2016. (Abstract)

338.   McCutcheon ST, Han D, Troncoso J, Koliatsos VE, Albert M, Lyketsos CG, Leoutsakos JS. Clinicopathological correlates of depression in early Alzheimer's disease in the NACC. Int J Geriatr Psychiatry, 31:1301-1311, Published 2016, PMC4983531.

339.   Mez J, Mukherjee S, Thornton T, Fardo DW, Trittschuh E, Sutti S, Sherva R, Kauwe JS, Naj AC, Beecham GW, Gross A, Saykin AJ, Green RC, Crane PK, ADGC Collaborators. The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable. Neurobiol Aging, 41:115-121, Published 2016, PMC4843522.

340.   Monsell SE, Dodge HH, Zhou XH, Bu Y, Besser LM, Mock C, Hawes SE, Kukull WA, Weintraub S, Neuropsychology Work Group Advisory to the Clinical Task Force. Results from the NACC Uniform Data Set neuropsychological battery Crosswalk Study. Alzheimer Dis Assoc Disord, 2:134-139, Published 2016, PMC4834278.

341.   Multani N, Rudzicz F, Tartaglia MC. Comparing neuropsychiatric and language features in early-onset and late-onset Alzheimer's disease. Alzheimers Dement, P490, Published 2016. (Abstract)

342.   Nel R. Asset Pricing of Life-Contingent Claims with n-State Stochastic Longevity Data Generating Process. Insurance: Mathematics and Economics, Submitted 2016.

343.   Nelson PT, Katsumata Y, Nho K, Artiushin SC, Jicha GA, Wang W, Abner EL, Saykin AJ, Kukull WA, Fardo DW. Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging. Acta Neuropathol, 132:841-858, Published 2016, PMC5154615.

344.   Nelson PT, Trojanowski JQ, Abner EL, Al-Janabi OM, Jicha GA, Schmitt FA, Smith CD, Fardo DW, Wang WX, Kryscio RJ, Neltner JH, Kukull WA, Cykowski MD, Van Eldik LJ, Ighodaro ET. New Old Pathologies: AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS). J Neuropathol Exp Neurol, 75:482-98, Published 2016, PMC in process.

345.   Nowrangi M, Rosenberg P, Leoutsakos JM. Subtle changes in daily functioning predict conversion from normal to mild cognitive impairment or dementia: an analysis of the NACC database. Int Psychogeriatr, 28:2009-2018, Published 2016, PMC5628501.

346.   O'Kelly N. Use of Machine Learning Technology in theDiagnosis of Alzheimer's Disease. A Thesis submitted to the School of Comupting, Dublin City University, Defended 2016.

347.   Owens M, Vazquez Brown M. Bilingual language distance predicts dementia rating. 62nd Annual Southeastern Psychological Association Conference, New Orleans, LA, Accepted 2016. (Abstract)

348.   Phillips JS, Irwin DJ, Rascovsky K, Van Deerlin VM, Lee VM, Trojanowski JQ, McMillan CT, Grossman M. Cognitive and Behavioral Trajectory of Behavioral-Variant Frontotemporal Dementia Differs According to Underlying Pathology. J Neurochem, 138:297-298, Published 2016. (Abstract)

349.   Pickrell JK, Berisa T, Liu JZ, Segurel L, Tung JY, Hinds DA, ADGC Collaborators. Detection and interpretation of shared genetic influences on 42 human traits. Nat Genet, 7:709-717, Published 2016, PMC5207801.

350.   Pillai JA, Appleby B, Safar J, Leverenz JB. Rapidly Progressive Alzheimer's Disease In Two Distinct Autopsy Cohorts. Neurology, 86:P5.183, Published 2016. (Abstract)

351.   Pillai JA, Butler RS, Bonner-Jackson A, Leverenz JB. Impact of Alzheimer's Disease, Lewy Body and Vascular Co-Pathologies on Clinical Transition to Dementia in a National Autopsy Cohort. Dement Geriatr Cogn Disord, 42:106-116, Published 2016, PMC5451902.

352.   Qian W, Fischer CE, Schweizer TA, Munoz DG. Cognitive and Functional Differences Between Delusions and Hallucinations in Alzheimer's Disease. Neurology, 86:P2.234, Published 2016. (Abstract)

353.   Qian W, Schweizer T, Munoz D, Fischer C. Misdiagnosis of Alzheimer's disease: Inconsistencies between clinical diagnosis and neuropathological confirmation. Alzheimers Dement, 12:P293, Published 2016. (Abstract)

354.   Qian W, Schweizer TA, Millikin CP, Ismail Z, Smith EE, Lix LM, Munoz DG, Fischer CE. Delusions in Alzheimer's disease are associated with prefrontal and cerebellar atrophy. Am J Geriatr Psychiatry, Supplement 1:S133, Published 2016. (Abstract)

355.   Qian W. Atrophy in the Default Mode Network Following the Development of Delusions in Patients with Alzheimer's Disease. Am J Geriatr Psychiatry, 24(3):S133 - S135, Published 2016. (Abstract)

356.   Ridge PG, Hoyt KB, Boehme K, Mukherjee S, Crane PK, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD, Kauwe JS, ADGC Collaborators. Assessment of the genetic variance of late-onset Alzheimer's disease. Neurobiol Aging, 41:200 e13-20, Published 2016, PMC4948179.

357.   Ringman J, Caceres N, Clark K, Chui H. Dopamine Responsive Features in Alzheimer's Disease, Alzheimer's Disease with Lewy Bodies (LB), and Pure LB Disease. Alzheimers Dement, 12:P737-P738, Published 2016. (Abstract)

358.   Ringman JM, Monsell S, Ng DW, Zhou Y, Nguyen A, Coppola G, Van Berlo V, Mendez MF, Tung S, Weintraub S, Mesulam MM, Bigio EH, Gitelman DR, Fisher-Hubbard AO, Albin RL, Vinters HV. Neuropathology of Autosomal Dominant Alzheimer Disease in the National Alzheimer Coordinating Center Database. J Neuropathol Exp Neurol, 75:284-290, Published 2016, PMC4934612.

359.   Ronquillo JG, Baer MR, Lester WT. Sex-specific patterns and differences in dementia and Alzheimer's disease using informatics approaches. J Women Aging, 28:403-411, Published 2016, PMC5110121.

360.   Saurman J, John S, Gurnani A, Bussell C, Grajzel K, Griffin JW, Gavett BE. Measurement Invariance of Dementia Severity in (δ). J Int Neuropsychol Soc, 22(s1), Published 2016. (Abstract)

361.   Serrano-Pozo A, Qian J, Muzikansky A, Monsell S, Montine TJ, Frosch MP, Bentensky RA, Hyman B. Thal amyloid stages do not significantly impact the correlation between neuropathological change and cognition in the Alzheimer disease continuum. J Neuropathol Exp Neurol, 75:516-526, Published 2016, PMC in process.

362.   Song X, Guo H, Siu W, D'Arcy RCN, Diggle J, Zhang Y. Application of Brain Atrophy Lesion Index (BALI) to Common Clinical MRI Sequences: Evaluation of Whole Brain Structural Changes in Aging and Dementia. Alzheimers Dement, 12:P101-P102, Published 2016. (Abstract)

363.   Srinivasan S, Bettella F, Mattingsdal M, Wang Y, Witoelar A, Schork AJ, Thompson WK, Zuber V, ADGC Collaborators. Genetic Markers of Human Evolution Are Enriched in Schizophrenia. Biol Psychiatry, 4:284-92, Published 2016, PMC5397584.

364.   Stabler A, Morris J. Conversion to mild cognitive impairment of cognitively normal older adults compared to research volunteers and clinic patients with baseline subjective memory complaints. J Int Neuropsychol Soc, 22(s1), Published 2016. (Abstract)

365.   Staley LA, Ebbert MT, Bunker D, Bailey M, Alzheimer's Disease Neuroimaging I, Ridge PG, Goate AM, Kauwe JSSADGC Collaborators. Variants in ACPP are associated with cerebrospinal fluid Prostatic Acid Phosphatase levels. BMC Genomics, 17 Suppl 3:439, Published 2016, PMC4943489.

366.   Staley LA, Ebbert MT, Parker S, Bailey, Ridge PG, Goate AM, Kauwe JS M,SADGC Collaborators. Genome-wide association study of prolactin levels in blood plasma and cerebrospinal fluid. BMC Genomics, 17 Suppl 3:436, Published 2016, PMC4943503.

367.   Swami S, Cohen R, Kairalla JA, Manini TM. Anticholinergic Drug Use and Risk to Cognitive Performance in Older Adults with Questionable Cognitive Impairment: A Cross-Sectional Analysis. Drugs Aging, 33:809-818, Published 2016, PMC5823249.

368.   Tse KH, Herrup K. Loss of Oligodendrocytes Is an Early Amyloid-Independent Event in the Progress of Dementia. Alzheimers Dement, 12:P457, Published 2016. (Abstract)

369.   Vidoni ED, Yeh HW, Morris JK, Newell KL, Alqahtani A, Burns NC, Burns JM, Billinger SA. Cerebral beta-Amyloid Angiopathy Is Associated with Earlier Dementia Onset in Alzheimer's Disease. Neurodegener Dis, 16:218-224, Published 2016, PMC4915344.

370.   Vitale GJ, Garcia J, Okolichany R, Tirado C, Golden CJ. Comparing Neuropsychological Outcomes for Sleep Apnea with Brain Injury. Arch Clin Neuropsychol, 31:6, Published 2016. (Abstract)

371.   Walter S, Marden JR, Kubzansky LD, Mayeda ER, Crane PK, Chang SC, Cornelis M, Rehkopf DH, Mukherjee S, Glymour MM, ADGC Collaborators. Diabetic Phenotypes and Late-Life Dementia Risk: A Mechanism-specific Mendelian Randomization Study. Alzheimer Dis Assoc Disord, 30:15-20, Published 2016, PMC4879683.

372.   Werry AE, Anderson SL, Daniel M. The influence of race and depression on processing speed and executive functioning in older adults. Clin Neuropsychol, 30(3):445, Published 2016. (Abstract)

373.   Werry AE, Daniel M, Bergstrom B. Ethnic Group Differences in Normal Neuropsychological Test Performance for Older Adults. Arch Clin Neuropsychol, 31(6):669, Published 2016. (Abstract)

374.   White MT, Shaw LM, Xie SX. Evaluation of Cerebrospinal Fluid Assay Variability in Alzheimer's Disease. J Alzheimers Dis, 51:463-470, Published 2016, PMC4930357.

375.   Woulfe K, Munoz D. Hachinski Ischemic Score As a Predictor of Infarcts in Alzheimer's Patients. Alzheimers Dement, 12:P694, Published 2016. (Abstract)

376.   Yang J, An N, Kowall NW, Farrer LA, Yuan J, Zhang Z, Au R. Data Driven Approaches for Predictors Selections in Determining Alzheimer's Disease. Alzheimers Dement, 12:P478, Published 2016. (Abstract)

377.   Yokoyama JS, Wang Y, Schork AJ, Thompson WK, Karch CM, Cruchaga C, McEvoy LK, Witoelar A, Chen CH, Holland D, Brewer JB, Franke A, Dillon WP, Wilson DM, Mukherjee P, Hess CP, Miller Z, Bonham LW, Shen J, Rabinovici GD, Rosen HJ, Miller BL, Hyman BT, Schellenberg GD, Karlsen TH, Andreassen OA, Dale AM, Desikan RS, Alzheimer's Disease Neuroimaging I. Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease. JAMA Neurol, 6:691-697, Published 2016, PMC4905783.

378.   Zhang Y, Zhou XH, Meranus DH, Wang L, Kukull WA. Benzodiazepine Use and Cognitive Decline in Elderly With Normal Cognition. Alzheimer Dis Assoc Disord, 30:113-117, Published 2016, PMC4670597.

379.   Zhu CW, Luo X, Schimming C, Grossman H, Sano M. Longitudinal effects of diabetes on cognitive decline: Results from the National Alzheimer's Coordinating Center's Uniform Data Set (NACC UDS). Alzheimers Dement, 12:P1175, Published 2016. (Abstract)

 
         2015
380.   Barnes J, Dickerson B, Frost C, Jiskoot LC, Wolk D, van der Flier WM. Alzheimer's disease first symptoms are age dependent: Evidence from the NACC dataset. Alzheimers Dement, 11:1349-1357, Published 2015, PMC4619185.

381.   Beecham GW, Dickson DW, Scott WK, Martin ER, Schellenberg G, Nuytemans K, Larson EB, Buxbaum JD, Trojanowski JQ, Van Deerlin VM, Hurtig HI, Mash DC, Beach TG, Troncoso JC, Pletnikova O, Frosch MP, Ghetti B, Foroud TM, Honig LS, Marder K, Vonsattel JP, Goldman SM, Vinters HV, Ross OA, Wszolek ZK, Wang L, Dykxhoorn DM, Pericak-Vance MA, Montine TJ, Leverenz JB, Dawson TM, Vance JM, ADGC Collaborators. PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease. Neurology, 84:972-980, Published 2015, PMC4352096.

382.   Bekris L, Tsuang D, Yu C, Kay, J, Krame, P, Woltje R, Trojanowski J, Weintraub D, Irwin D, Chen-Plotkin A, Schellenberg G, Watson S, Kukull W, Nelso, P, Jicha G, Galasko D, Masliah E, Quinn J, Chung K , Edwards K, Lopez O, Hamilton R, Bennett D, Schneider J, Buchman A, Crane P, Larson E, Yearout D, Mata I, Montine T, Zabetian C, Leverenz J. APOE and TOMM40 Association with Lewy Body Disease and Other Dementias. Am J Neurodegener Dis, Supplementary Issue 1:102, Published 2015. (Abstract)

383.   Bernier P, Gourdeau C, Carmichael P, Beauchemin J, Verreault R, Bouchard R, Kroger E, Laforce R. Applying ‘growth curves' to age-associated cognitive decline: an innovative method to help determine normal vs. abnormal longitudinal cognitive changes in the elderly. Alzheimers Dement, 7:P711-P712, Published 2015. (Abstract)

384.   Besser L, Monsell S, Beekly D, Kukull W. Clinical Characteristics Associated with Neuropathological Lewy Body Disease Subtypes Among Non-Demented Subjects in the Uniform Data Set. Am J Neurodegener Dis, Supplementary Issue 1:65, Published 2015. (Abstract)

385.   Blacker D, Qian J, Beiser A, Haan M, Karlawish J, Langbaum JB, Neuhaus JM, Reiman EM, Seshadri S, Tariot PN, Betensky RA. ApoE risk in the Alzheimer's prevention initiative. Alzheimers Dement, 11:154 - 155, Published 2015. (Abstract)

386.   Brenowitz WD, Nelson PT, Besser LM, Heller KB, Kukull WA. Cerebral amyloid angiopathy and its co-occurrence with Alzheimer's disease and other cerebrovascular neuropathologic changes. Neurobiol Aging, 36:2702-2708, Published 2015, PMC4562901.

387.   Brown DS, Hynan LS, Weiner M, Lacritz LH, Minhajuddin A. The Relationship of Metabolic Syndrome to Cognitive Variability Across Time in an Elderly Sample. International Neuropsychological Society 43rd Annual Meeting, Denver, CO, Accepted 2015. (Abstract)

388.   Bulik-Sullivan B, Finucane HK, Anttila V, Gusev A, Day FR, Loh PR, Duncan L, Perry JR, Patterson N, Robinson EB, Daly MJ, Price AL, Neale BM, ADGC Collaborators. An atlas of genetic correlations across human diseases and traits. Nat Genet, 47:1236-1241, Published 2015, PMC4797329.

389.   Burke SL, Maramaldi P, Cadet T, Kukull W. Associations between depression, sleep disturbance and Apolipoprotein E in the development of Alzheimer's disease: dementia. Int Psychogeriatr, 28:1409-1424, Published 2015, PMC4963299.

390.   Callahan BL, Duchesnea S, Black SE. Vasculopathological characteristics of empirically-derived subtypes of mild cognitive impairment and dementia. Alzheimers Dement, 11(7s):827, Published 2015. (Abstract)

391.   Caselli RJ, Dueck AC, Locke DE, Baxter LC, Woodruff BK, Geda YE. Sex-Based Memory Advantages and Cognitive Aging: A Challenge to the Cognitive Reserve Construct?. J Int Neuropsychol Soc, 21:95-104, Published 2015, PMC4785799.

392.   Chen B, Zhou XH, Chan KC. Pseudo-empirical Likelihood-Based Method Using Calibration for Longitudinal Data with Drop-Out. J Royal Stat Soceity Series C, 64:157-174, Published 2015, PMC4288856.

393.   Chung EJ, Babulal GM, Monsell SE, Cairns NJ, Roe CM, Morris JC. Clinical Features of Alzheimer Disease With and Without Lewy Bodies. JAMA Neurol, 72:789-796, Published 2015, PMC4501861.

394.   Chung EJ, Babulal GM, Monsell SE, Cairns NJ. Clinical features of Alzheimer Disease with and without Lewy Bodies. Alzheimers Dement, 11(7):428-429, Published 2015. (Abstract)

395.   Clem MA, Pandya SY, Holliday RH, Lacritz LH, Woon FL. Baseline Neuropsychiatric Symptoms and Stability of Mild Cognitive Impairment. 43rd annual meeting of the International Neuropsychological Society, Denver, CO, Accepted 2015. (Abstract)

396.   Cohen ML, Kim C, Haldiman T, ElHag M, Mehndiratta P, Pichet T, Lissemore F, Shea M, Cohen Y, Chen W, Blevins J, Appleby BS, Surewicz K, Surewicz WK, Sajatovic M, Tatsuoka C, Zhang S, Mayo P, Butkiewicz M, Haines JL, Lerner AJ, Safar JG. Rapidly progressive Alzheimer's disease features distinct structures of amyloid-beta. Brain, 138:1009-1022, Published 2015, PMC5014074.

397.   Conniff K, Moorleghem KV, Gill S, Posecion L, L. C, Nunan-Saah J, Paulraj S, Gomez R. Can Depression Predict Functional Impairment in Lewy Body Dementia?. Arch Clin Neuropsychol, 6:531, Published 2015. (Abstract)

398.   Cukier HN, Kunkle BW, Rolati S, Hamilton-Nelson KL, Kohli MA, Dombroski BA, Vardarajan BN, Whitehead PL, Van Booven DJ, Martin ER, Beecham GW, Farrer LA, Cuccaro ML, Vance JM, Mayeux R, Gilbert JR, Carney RM, Byrd GS, Haines JL, Schellenberg GD, Pericak-Vance MA, Lang R, ADGC Collaborators. ABCA7 Deletion Associated with Alzheimer's Disease in African Americans. Alzheimers Dement, 11(7):485-486, Published 2015. (Abstract)

399.   Cullum M, Lobue C, Denney D, Hynan L, Rossetti H, Lacritz L, Hart J, Womack K. Traumatic Brain Injury History and Age of Mild Cognitive Impairment Diagnosis. Alzheimers Dement, 11(7):444, Published 2015. (Abstract)

400.   Deutsch MB, Mendez MF, Teng E. Interactions between traumatic brain injury and frontotemporal degeneration. Dement Geriatr Cogn Disord, 39:143-153, Published 2015, PMC4427348.

401.   Fischer CE, Qian W, Schweizer TA, Millikin C, Ismail Z, Smith EE, Lix LM, Shelton P, Munoz D. Lewy Bodies, Vascular Risk Factors, and Subcortical Arteriosclerotic Leukoencephalopathy, but not Alzheimer Pathology, are Associated with Development of Psychosis in Alzheimer's Disease. J Alzheimers Dis, 50:283-295, Published 2015, PMC4844451.

402.   Fischer CE, Qian W, Schweizer TA, Millikin C, Ismail Z, Smith EE, Lix LM, Shelton P, Munoz DG. Vascular risk factors and Subcortical Arteriosclerotic Leukoencephalopathy, but not Alzheimer lesion load, are associated with the development of psychosis in Alzheimer's disease. Can Geriatr J, 18(4):246, Published 2015. (Abstract)

403.   Fischer CE, Qian W, Schweizer TA, Millikin CP, Ismail Z, Smith EE, Lix LM, Shelton P, Munoz DG. Vascular risk factors and Subcortical Arteriosclerotic Leukoencephalopathy, but not Alzheimer lesion load, are associated with the development of psychosis in Alzheimer's disease. Am J Geriatr Psychiatry, 24(3) Supplement 1:S142, Published 2015. (Abstract)

404.   Gavett B, John S. Rethinking Abnormal Test Scores in Normal People: Application of Base Rate Data to the Individual Patient. Arch Clin Neuropsychol, 30(6):594-595, Published 2015. (Abstract)

405.   Gavett BE, Ashendorf L, Gurnania AS. Reliable Change on Neuropsychological Tests in the Uniform Data Set. J Int Neuropsychol Soc, 21:558-567, Published 2015, PMC4860819.

406.   Gavett BE, John SE, Gurnani AS, Bussell CA, Saurman JL. The Role of Alzheimer's and Cerebrovascular Pathology in Mediating the Effects of Age, Race, and Apolipoprotein E Genotype on Dementia Severity in Pathologically-Confirmed Alzheimer's Disease. J Alzheimers Dis, 49:531-545, Published 2015, PMC4858176.

407.   Gavett BE, Vudy V, Jeffrey M, John SE, Gurnani A, Adams J. The delta latent dementia phenotype in the uniform data set: Cross-validation and extension. Neuropsychology, 29:344-352, Published 2015, PMC4340822.

408.   Gavett BE. Neuropathology Mediates Age, Race, and APOE effects on δ in Pathologically Confirmed AD. Symposium presented at the 43rd Annual Meeting of the International Neuropsychological Society, Denver, CO, Accepted 2015. (Abstract)

409.   Ghani M, Reitz C, Cheng R, Lee JH, Vardarajan BN, Tosto G, St George-Hyslop P, Mayeux R, Rogaeva E, ADGC Collaborators. Genome Wide Analyses of Runs of Homozygosity Among African Americans Revealed Further Evidence of Recessive Inheritance for Alzheimer's Disease. Alzheimers Dement, 11(7):228, Published 2015. (Abstract)

410.   Ghani M, Reitz C, Cheng R, Vardarajan BN, Jun G, Sato C, Naj A, Rajbhandary R, Wang L, Valladares O, Lin C, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin D, Go RCP, Griffith P, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hendrie H, Hall KS, Goate AM, Byrd GS, Kukull WA, Foroud TM, Haines JL, Farrer LA, Pericak-Vance MA, Lee JH, Schellenberg GD, George-Hyslop PS, Mayeux R, Rogaeva E, ADGC Collaborators. Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. JAMA Neurol, 72:1313-1323, Published 2015, PMC4641052.

411.   Gifford KA, Liu D, Hohman TJ, Xu M, Han X, Romano RR, 3rd, Fritzsche LR, Abel T, Jefferson AL. A Mutual Self- and Informant-Report of Cognitive Complaint Correlates with Neuropathological Outcomes in Mild Cognitive Impairment. PLoS One, 10:e0141831, Published 2015, PMC4634952.

412.   Grill JD, Vinters HV, Monsell SE. Does Alzheimer Disease Pathologic Change Underlie Subjective Cognitive Complaints?. Alzheimer Dis Assoc Disord, 29:350-352, Published 2015, PMC4643424.

413.   Hassenstab J, Monsell SE, Mock C, Roe CM, Cairns NJ, Morris JC, Kukull W. Neuropsychological Markers of Cognitive Decline in Persons With Alzheimer Disease Neuropathology. J Neuropathol Exp Neurol, 74:1086-1092, Published 2015, PMC4610245.

414.   Hohman TJ, Samuels LR, Liu D, Gifford KA, Mukherjee S, Benson EM, Abel T, Ruberg FL, Jefferson AL. Stroke risk interacts with Alzheimer's disease biomarkers on brain aging outcomes. Neurobiol Aging, 36:2501-2508, Published 2015, PMC4523400.

415.   Hsiao JJ, Lu PH, Grill JD, Teng E. Longitudinal declines in instrumental activities of daily living in stable and progressive mild cognitive impairment. Dement Geriatr Cogn Disord, 39:12-24, Published 2015, PMC4312538.

416.   Ighodaro ET, Abner EL, Monsell SE, Kukull WA, Nelson PT. Decoding the Risk Factors and Cognitive Consequences of a Common Vascular Pathology: Brain Arteriolosclerosis. 91st Annual Meeting of the American-Association-of-Neuropathologists-Inc, 74:604, Published 2015. (Abstract)

417.   Int'l Genomics of AD Consortium (IGAP). Convergent genetic and expression data implicate immunity in Alzheimer's disease. Alzheimers Dement, 11:658-671, Published 2015, PMC4672734.

418.   Irwin D, Grossman H, Weintraub D, Hurtig H, Duda J, Lopez O, Kofler J, Nelson P, Woltje R, Quinn J, Kaye J, Leverenz J, Tsuang D, Longfellow K, Kukull W, Montine T, Zabetian C, Trojanowski J. Neuropathological Influences on the Clinical Phenotype of Lewy Body Dementias. Am J Neurodegener Dis, Supplementary Issue 1:148, Published 2015. (Abstract)

419.   Jefferson AL, Hohman TJ, Liu D, Haj-Hassan S, Gifford KA, Benson EM, Skinner JS, Lu Z, Sparling J, Sumner EC, Bell S, Ruberg FL. Adverse vascular risk is related to cognitive decline in older adults. J Alzheimers Dis, 44:1361-1373, Published 2015, PMC4336578.

420.   John SE, Gurnani AS, Gavett BE. Use of the Latent Dementia Phenotype for Differential Diagnosis in the NACC UDS. National Academy of Neuropsychology, Austin, TX, Accepted 2015. (Abstract)

421.   Jun G, Chung J, Tosto G, Vardarajan B, Reitz C, Lunetta KL, Manly JJ, Byrd GS, Haines JL, Pericak-Vance MA, Kuwano R, Mayeux R, Schellenberg GD, Farrer LA, ADGC Collaborators. Transethnic Genome-Wide Meta-Analysis for Alzheimer Disease. Alzheimers Dement, 11(7):230, Published 2015. (Abstract)

422.   Khan A, Usman M. Early Diagnosis of Alzheimer's disease Using Machine Learning Techniques. Proceedings of the 7th International Joint Conference on Knowledge Discovery, Knowledge Engineering and Knowledge Management, 380-387, Published 2015. (Abstract)

423.   Kielb S, Rogalski E, Weintraub S. Subjective cognitive complaints and early cognitive features of preclinical AD. J Int Neuropsychol Soc, 21(S1):181, Published 2015. (Abstract)

424.   Kielb S, Weitner BB, Rogalski E, Weintraub S, Rademaker A. Subjective cognitive complaints are associated with longitudinal changes in immediate memory recall. Alzheimers Dement, 11(7):342, Published 2015. (Abstract)

425.   Kukull W. Insights from the National Alzheimer's Coordinating Center (NACC) for DLB Research. Am J Neurodegener Dis, Supplementary Issue 1:57, Published 2015. (Abstract)

426.   Leoutsakos JS, Forrester SN, Geda YE, Lyketsos C. NPS in normal cognition and the risk of developing MCI and dementia in the presence of late onset NPS. Alzheimers Dement, 11(7):309-310, Published 2015. (Abstract)

427.   Leoutsakos JS, Forrester SN, Lyketsos CG, Smith GS. Latent Classes of Neuropsychiatric Symptoms in NACC Controls and Conversion to Mild Cognitive Impairment or Dementia. J Alzheimers Dis, 48:483-493, Published 2015, PMC4635658.

428.   Liang X, Liu YW. Cognitive Impairment Progression Analysis Using Agent-Based Simulation Approach. ISERC, Accepted 2015. (Abstract)

429.   Liu D, Zhou XH. Estimation of ROC curve with multiple types of missing gold standard. In: Chen Z, Liu AQ, Y., Tang L, Ting N, Tsong Y, eds. Applied Statistics in Biomedicine and Clinical Trials Design. ICSA Book Series in Statistics: Sp, 75-87, Published 2015.

430.   LoBue C, Clem M, Wilmoth K, Lacritz L, Woon FL, Rossetti HC, Cullum CM. Traumatic brain injury is associated with earlier age of diagnosis in mild cognitive impairment regardless of gender. 35th annual National Academy of Neuropsychology conference, Austin, TX, Accepted 2015. (Abstract)

431.   LoBue C, Lacritz LH, Rossetti HC, Hart J, Womack KB, Cullum CM. Self-reported head injury and age of diagnosis in dementia. 43rd annual meeting of the International Neuropsychological Society, Denver, CO, Accepted 2015. (Abstract)

432.   Maddox RA, Blase JL, Mercaldo ND, Gambetti P, Harvey AR, Schonberger LB, Kukull WA, Belay ED. Clinically Unsuspected Prion Disease Among Patients With Dementia Diagnoses in an Alzheimer's Disease Database. Am J Alzheimers Dis Other Demen, 30:752-755, Published 2015, PMC4651736.

433.   Masters MC, Morris JC, Roe CM. "Noncognitive" symptoms of early Alzheimer disease. A longitudinal analysis. Neurology, 84:617-622, Published 2015, PMC4335988.

434.   Mendez MF, Paholpak P, Lin A, Zhang JY, Teng E. Prevalence of Traumatic Brain Injury in Early Versus Late-Onset Alzheimer's Disease. J Alzheimers Dis, 47:985-993, Published 2015, PMC4753056.

435.   Moga DC, Gnjidic D, Jicha G. Sex-specific Associations for Predicting Psychotropic Drug Use in Older Adults with Cognitive Impairment. Pharmacoepidemiol Drug Saf, 24(S1):425-426, Published 2015. (Abstract)

436.   Moga DC, Wu Q, Gnjidic D, Jicha G. Sex-differences Pertaining to Diagnosis and Treatment of Dementia: a USA Perspective. Podium presentation at the Gerontological Society of America Annual Meeting, November 22, 2015, Orlando, FL, Accepted 2015. (Abstract)

437.   Monsell SE, Mock C, Fardo DW, Bertelson S, Cairns NJ, Roe CM, Morris JC, Goate A, Kukull WA. Genetic differences between symptomatic and asymptomatic persons with Alzheimer's disease neuropathologic change. Alzheimers Dement, 11(7):767, Published 2015. (Abstract)

438.   Monsell SE, Hassenstab J, Mock C, Roe CM, Cairns NJ, Morris JC, Kukull WA. Neuropsychological markers of cognitive decline in persons with Alzheimer's disease neuropathology. Alzheimers Dement, 11(7):240-241, Published 2015. (Abstract)

439.   Monsell SE, Kukull WA, Roher AE, Maarouf CL, Serrano G, Beach TG, Caselli RJ, Montine TJ, Reiman EM. Characterizing Apolipoprotein E epsilon4 Carriers and Noncarriers With the Clinical Diagnosis of Mild to Moderate Alzheimer Dementia and Minimal beta-Amyloid Peptide Plaques. JAMA Neurol, 72:1124-1131, Published 2015, PMC4833059.

440.   Montgomery V, Stabler A, Harris K, Lu L. Effects of Delay Duration on the Wechsler Memory Scale Logical Memory Performance of Older Adults with Probable Alzheimer's Dementia, Probable Vascular Dementia, and Normal Cognition. Arch Clin Neuropsychol, 30:531, Published 2015. (Abstract)

441.   Moulder KL, Monsell SE, Beekly D, Besser LM, Blennow K, Kukull W, Morris JC. Factors Influencing Lumbar Puncture Participation in Alzheimer Research. Alzheimers Dement, 11(7):780, Published 2015. (Abstract)

442.   Mukherjee S, Boehme KL, Naj AC, Fardo DW, Kauwe J, Manly JJ, Montine TJ, Crane PK, ADGC Collaborators. Integrating Human Protein-Protein Interaction Network with Results from Gwas in Whites and African-Americans Identifies Common Genes Underlying Late-Onset Alzheimer's Disease. Alzheimers Dement, 11(7):299, Published 2015. (Abstract)

443.   Mukherjee S, Walter S, Kauwe JS, Saykin AJ, Bennett DA, Larson EB, Crane PK, Glymour MM, ADGC Collaborators. Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses. Alzheimers Dement, 11:1439-1451, Published 2015, PMC4676945.

444.   Nelson PT, Wang WX, Partch AB, Monsell S, Valladares O, Ellingson SR, Wilfred BR, Naj AC, Wang LS, Kukull WA, Fardo DW. Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology. J Neuropathol Exp Neurol, 74:75-84, Published 2015, PMC4270894.

445.   Onyike C, Kansal K, Amjad H. Longitudinal comparisons of global measures of cognitive, behavioral and functional decline in frontotemporal dementia. Int Psychogeriatr, 27:S116-S116, Published 2015. (Abstract)

446.   Ossenkoppele R, Jansen WJ, Rabinovici GD, Knol DL, van der Flier WM, van Berckel BN, Scheltens P, Visser PJ, Verfaillie SC, Zwan MD, Adriaanse SM, Lammertsma AA, Barkhof F, Jagust WJ, Miller BL, Rosen HJ, Landau SM, Villemagne VL, Rowe CC, Lee DY, Na DL, Seo SW, Sarazin M, Roe CM, Sabri O, Barthel H, Koglin N, Hodges J, Leyton CE, Vandenberghe R, van Laere K, Drzezga A, Forster S, Grimmer T, Sanchez-Juan P, Carril JM, Mok V, Camus V, Klunk WE, Cohen AD, Meyer PT, Hellwig S, Newberg A, Frederiksen KS, Fleisher AS, Mintun MA, Wolk DA, Nordberg A, Rinne JO, Chetelat G, Lleo A, Blesa R, Fortea J, Madsen K, Rodrigue KM, Brooks DJ. Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis. JAMA, 313:1939-1949, Published 2015, PMC4517678.

447.   Ostergaard SD, Mukherjee S, Sharp SJ, Proitsi P, Lotta LA, Day F, Perry JR, Boehme KL, Walter S, Kauwe JS, Gibbons LE, Larson EB, Powell JF, Langenberg C, Crane PK, Wareham NJ, Scott RA, ADGC Collaborators. Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study. PLoS Med, 12:e1001841; discu, Published 2015, PMC4469461.

448.   Pandya S, Clem M, Cullum M, Woon F. Predicting Progression from Mild Cognitive Impairment to Dementia with CAIDE Dementia Risk Score. Arch Clin Neuropsychol, 30:530-531, Published 2015. (Abstract)

449.   Pandya SY, Clem MA, Horton DK, Lacritz LH, Woon FL. Predictors of Reversion from Mild Cognitive Impairment to Normal Cognition. 43rd annual meeting of the International Neuropsychological Society, Denver, CO, Accepted 2015. (Abstract)

450.   Pillai JA, Butler RS, Bonner-Jackson A, Leverenz JB. Slower Annual Rate of Cognitive and Functional Decline in Mixed Dementia Compared to Pure Alzheimer's Dementia Relates to Lower Braak Stage of Alzheimer Neuropathology. Alzheimers Dement, 11(7):435, Published 2015. (Abstract)

451.   Qian W. Atrophy in the Default Mode Network Following the Development of Delusions in Patients with Alzheimer's Disease. Can Geriatr J, 18(4):264-265, Published 2015. (Abstract)

452.   Qian W. Delusions in Alzheimer's disease are associated with prefrontal and cerebellar atrophy. Can Geriatr J, 18(4):264, Published 2015. (Abstract)

453.   Riccio P, Sposato LA, Vargas ER, Toledo J, Trojanowski J, Hachinski V. Atrial Fibrillation in Patients with Neuropathological Diagnosis of Primary Alzheimer's Disease. Neurology, 84:SI9-5A and S16.002:1526-1632X, Published 2015. (Abstract)

454.   Ringman J, Monsell S, Nguyen A, Tung S, Zhou Y, Ng D, Vinters H. Prevalence of cerebral amyloid angiopathy on autopsy in autosomal dominant Alzheimer's disease. Neurology, 84:S33.008, Published 2015. (Abstract)

455.   Rochani HD, Samawi HM, Linder DF. Maximum likelihood estimates by Homogenous log-linear models for three-way contingency tables with Missing data with application to neuropathology data. Paper presented at the APHA 2016, Chicago, Accepted 2015. (Abstract)

456.   Ronquillo JG, Baer MR, Lester WT. Sex-specific patterns and differences in dementia and Alzheimer's disease using informatics approaches. AMIA 2015 Joint Summits on Translational Science (Summit on Translational Bioinformatics), Accepted 2015. (Abstract)

457.   Sayegh P. Neuropsychological Language Tests in Dementia Diagnosis in English-Speaking Hispanic and Non-Hispanic White Outpatients. Appl Neuropsychol Adult, 22:435-444, Published 2015, PMC4629774.

458.   Serrano-Pozo A, Hyman B. Alzheimer Disease: Alzheimer dementia with sparse amyloid—AD mimic or variant?. Nat Rev Neurol, 11:674-5, Published 2015.

459.   Serrano-Pozo A, Qian J, Monsell S, Betensky R, Hyman B. APOE2 is associated with milder clinical and pathological Alzheimer's disease. Neurology, 84:S16.005, Published 2015. (Abstract)

460.   Serrano-Pozo A, Qian J, Monsell S, Betensky R, Hyman B. APOEepsilon2 is associated with milder clinical and pathological Alzheimer disease. Ann Neurol, 77:917-929, Published 2015, PMC4447539.

461.   Snowden MB, Atkins DC, Steinman LE, Bell JF, Bryant LL, Copeland C, Fitzpatrick AL. Longitudinal Association of Dementia and Depression. Am J Geriatr Psychiatry, 23:897-905, Published 2015, PMC4369182.

462.   Steed D, Miller S. Differential Predictive Influence on the Development of Dementia: Depression and Neuropsychiatric Symptoms. J Int Neuropsychol Soc, 21(s1):202, Published 2015. (Abstract)

463.   Steed D, Miller S. Predicting Development of Dementia: A Parallel Process Latent Growth Curve Analysis. J Int Neuropsychol Soc, 21(s1):14-15, Published 2015. (Abstract)

464.   Torralva T, Sposato LA, Riccio PM, Gleichgerrcht E, Roca M, Toledo JB, Trojanowski JQ, Kukull WA, Manes F, Hachinski V. Role of brain infarcts in behavioral variant frontotemporal dementia: Clinicopathological characterization in the National Alzheimer's Coordinating Center database. Neurobiol Aging, 36:2861-2868, Published 2015, PMC4562890.

465.   Tosto G, Monsell SE, Hawes SE, Giuseppe B, Mayeux R. Progression of Extrapyramidal Signs in Alzheimer's Disease: Clinical and Neuropathological Correlates. J Alzheimers Dis, 49:1085-93, Published 2015, PMC4779642.

466.   Tosto G, Monsell SE, Hawes S, Mayeux R. Pattern of extrapyramidal signs in Alzheimer's disease. J Neurol, 262:2548-2556, Published 2015, PMC4776751.

467.   Tripodis Y, Zirogiannis N, Gavett BE, Chaisson C, Martin B, Kowall NW, Stern RA. Rate of decline for AD patients with history of traumatic brain injury. Alzheimers Dement, 11(7):382-383, Published 2015. (Abstract)

468.   Tse KH, Cheng A, Chow HM, Herrup K. White Matter Degeneration and Aberrant Oligodendrocyte Differentiation During the Progress of Alzheimer's Disease. Society for Neuroscience 2015, Chicago, Accepted 2015. (Abstract)

469.   Tsuang D, Vardarajan BN, Bird TD, Boeve B, Schaid D, Taner N, Allen M, Barral S, Bennett DA, Cruchaga C, Goate A, Graff-Radford N, Faber K, Farlow MR, Foroud TM, Ottman R, Rosenberg RN, Rumbaugh M, Sano M, Schellenberg GD, Silverman J, Sweet R, Mayeux R, NIA-LOAD/NCRAD Family Study Group, ADGC Collaborators. MAPT haplotypes modify the association between head injury and risk of Alzheimer's disease. Alzheimers Dement, 11(7):361, Published 2015. (Abstract)

470.   Viswanathan A, Macklin EA, Betensky R, Hyman B, Smith EE, Blacker D. The Influence of Vascular Risk Factors and Stroke on Cognition in Late Life: Analysis of the NACC Cohort. Alzheimer Dis Assoc Disord, 29:287-293, Published 2015, PMC4514567.

471.   Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E, Lin CF, Dombroski BA, Cantwell LB, Partch A, Valladares O, Hakonarson H, St George-Hyslop P, Green RC, Goate AM, Foroud TM, Carney RM, Larson EB, Behrens TW, Kauwe JS, Haines JL, Farrer LA, Pericak-Vance MA, Mayeux R, Schellenberg GD, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barmada MM, Barnes LL, Beach TG, Becker JT, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carroll SL, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Graff-Radford NR, Growdon JH, Hamilton RL, Hamilton-Nelson KL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Kamboh MI, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, Kramer P, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lopez OL, Lunetta KL, Lyketsos CG, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam MM, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Murrell JR, Olichney JM, Parisi JE, Perry W, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. JAMA Neurol, 72:209-216, Published 2015, PMC4324097.

472.   Wang W, Lin CF, Partch AB, Valladares O, Cantwell L, Naj AC, Wang LS, Schellenberg GD, ADGC Collaborators. Multiple Deletion Copy Number Variants (CNVs) Are Associated with Late-Onset Alzheimer's Disease: The Alzheimer's Disease Genetics Consortium. Alzheimers Dement, 11(7):228-229, Published 2015. (Abstract)

473.   Wharton W, Goldstein FC, Zhao L, Steenland K, Levey AI, Hajjar I. Certain Antihypertensives May Slow the Conversion from Mild Cognitive Impairment to Alzheimer's Disease. Alzheimers Dement, 11(7):290, Published 2015. (Abstract)

474.   Wharton W, Goldstein FC, Zhao L, Steenland K, Levey AI, Hajjar I. Modulation of Renin-Angiotensin System May Slow Conversion from Mild Cognitive Impairment to Alzheimer's Disease. J Am Geriatr Soc, 63:1749-1756, Published 2015, PMC4743657.

475.   Wyman-Chick KA, Scott BJ. Development of Clinical Dementia Rating Scale Cutoff Scores for Patients with Parkinson's Disease. Mov Disord Clin Pract, 2:243-248, Published 2015, PMC4675151.

476.   Xiong GL, Filshtein T, Beckett LA, Hinton L. Antipsychotic Use in a Diverse Population With Dementia: A Retrospective Review of the National Alzheimer's Coordinating Center Database. J Neuropsychiatry Clin Neurosci, 27:326-332, Published 2015, PMC4617662.

477.   Zhang JY, Lin A, Jimenez E, Paholpak P, Teng E, Mendez MF. Prevalence of Traumatic Brain Injury in Early versus Late-onset Alzheimer's Disease. Neurology, 84:P2.177, Published 2015. (Abstract)

 
         2014
478.   Allen M, Kachadoorian M, Quicksall Z, Zou F, Chai HS, Younkin C, Crook JE, Pankratz VS, Carrasquillo MM, Krishnan S, Nguyen T, Ma L, Malphrus K, Lincoln S, Bisceglio G, Kolbert CP, Jen J, Mukherjee S, Kauwe JK, Crane PK, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, ADGC Collaborators, Parisi JE, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N. Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels. Alzheimers Res Ther, 6:39, Published 2014, PMC4198935.

479.   Altmann A, Tian L, Henderson VW, Greicius MD. Sex modifies the APOE-related risk of developing Alzheimer's disease. Ann Neurol, 75:563-573, Published 2014, PMC4117990.

480.   Anor CJ, Hu B, Multani N, Tartaglia MC. Examining the Association between Neuropsychiatric Symptoms, Hypertension, Hypercholesterolemia, and Diabetes in Alzheimer's disease. Alzheimers Dement, 10:P364, Published 2014. (Abstract)

481.   Aranda MP, Lloyd D. Disparities in cognitive function and rate of decline by race/ethnicity. American Psychiatric Association Annual Meeting, New York City, NY, Accepted 2014. (Abstract)

482.   Barral S, Cosentino S, Christensen K, Newman AB, Perls TT, Province MA, Mayeux R. Common genetic variants on 6q24 associated with exceptional episodic memory performance in the elderly. JAMA Neurol, 71:1514-1519, Published 2014, PMC4355405.

483.   Barral S, Reitz C, Small SA, Mayeux R. Genetic variants in a 'cAMP element binding protein' (CREB)-dependent histone acetylation pathway influence memory performance in cognitively healthy elderly individuals. Neurobiol Aging, 35:e2887-2881 e281, Published 2014, PMC4253058.

484.   Beach TG, Schneider JA, Sue LI, Serrano G, Dugger BN, Monsell SE, Kukull W. Theoretical impact of Florbetapir (18F) amyloid imaging on diagnosis of alzheimer dementia and detection of preclinical cortical amyloid. J Neuropathol Exp Neurol, 73:948-953, Published 2014, PMC4169306.

485.   Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel JP, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Kamboh MI, Kofler JK, Mash DC, Duque L, Gilbert JR, Gwirtsman H, Buxbaum JD, Kramer P, Dickson DW, Farrer LA, Frosch MP, Ghetti B, Haines JL, Hyman BT, Kukull WA, Mayeux RP, Pericak-Vance MA, Schneider JA, Trojanowski JQ, Reiman EM, Schellenberg GD, Montine TJ. Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias. PLoS Genet, 10:e1004606, Published 2014, PMC4154667.

486.   Benitez BA, Jin SC, Guerreiro R, Graham R, Lord J, Harold D, Sims R, Lambert JC, Gibbs JR, Bras J, Sassi C, Harari O, Bertelsen S, Lupton MK, Powell J, Bellenguez C, Brown K, Medway C, Haddick PC, van der Brug MP, Bhangale T, Ortmann W, Behrens T, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Haines JL, Turton J, Braae A, Barber I, Fagan AM, Holtzman DM, Morris JC, Williams J, Kauwe JS, Amouyel P, Morgan K, Singleton A, Hardy J, Goate AM, Cruchaga C, ADGC Collaborators. Missense variant in TREML2 protects against Alzheimer's disease. Neurobiol Aging, 35:1510 e1519-1526, Published 2014, PMC3961557.

487.   Benson G, de Felipe J, Xiaodong, Sano M. Performance of Spanish-speaking community-dwelling elders in the United States on the Uniform Data Set. Alzheimers Dement, 10:S338-343, Published 2014, PMC4092047.

488.   Berres M, Kukull WA, Miserez AR, Monsch AU, Monsell SE, Spiegel R. A Novel Study Paradigm for Long-term Prevention Trials in Alzheimer Disease: The Placebo Group Simulation Approach (PGSA). Application to MCI data from the NACC database. J Prev Alzheimers Dis, 1:99-109, Published 2014, PMC4268776.

489.   Besser L, Monsell S, Heller K, Litvan I, Kukull W. Mild Cognitive Impairment among Parkinson's Disease subjects in the Uniform Data Set. Alzheimers Dement, 10:P689-690, Published 2014. (Abstract)

490.   Besser LM, Gill DP, Monsell SE, Brenowitz W, Meranus DH, Kukull W, Gustafson DR. Body Mass Index, Weight Change, and Clinical Progression in Mild Cognitive Impairment and Alzheimer Disease. Alzheimer Dis Assoc Disord, 28:36-43, Published 2014, PMC3945175.

491.   Brenowitz WD, Kukull WA, Beresford SA, Monsell SE, Williams EC. Social Relationships and Risk of Incident Mild Cognitive Impairment in US Alzheimer's Disease Centers. Alzheimer Dis Assoc Disord, 28:253-260, Published 2014, PMC4139444.

492.   Brenowitz WD, Monsell SE, Schmitt FA, Kukull WA, Nelson PT. Hippocampal sclerosis of aging is a key Alzheimer's disease mimic: clinical-pathologic correlations and comparisons with both alzheimer's disease and non-tauopathic frontotemporal lobar degeneration. J Alzheimers Dis, 39:691-702, Published 2014, PMC3946156.

493.   Chen B, Qin J. Test the reliability of doubly robust estimation with missing response data. Biometrics, 70:289-298, Published 2014, PMC4061274.

494.   Chen B, Qin J. Use of empirical likelihood to calibrate auxiliary information in partly linear monotone regression models. Stat Med, 33:1713-1722, Published 2014, PMC3981901.

495.   Clem M, Pandya S, Horton D, Hynan L, Lacritz L, Woon F. A-80Neuropsychological Prediction of Diagnostic Stability of Mild Cognitive Impairment. Arch Clin Neuropsychol, 29:533, Published 2014. (Abstract)

496.   Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Erin L. Abner P, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, Hyman BT, Jicha GA, Jellinger K, Kovacs GG, Knopman DS, Kofler J, Kukull WA, Mackenzie IR, Masliah E, McKee AC, Montine TJ, Murray ME, Neltner JH, Santa-Maria I, Seeley WW, Serrano-Pozo A, Shelanski ML, Stein TD, Takao M, Thal DR, Toledo JB, Troncoso JC, Vonsattel JP, 3rd CLW, Wisniewski T, Woltjer RL, Yamada M, Nelson PT. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathol, 128:755-766, Published 2014, PMC4257842.

497.   Cummings JL, Ringman J, Vinters H. Neuropathologic correlates of trial-related instruments for Alzheimer's disease. Am J Neurodegener Dis, 3:45-49, Published 2014, PMC3986610.

498.   Deutsch M, Mendez M, Teng E. Medical risk factors for frontotemporal degeneration: Analysis of the NACC Uniform Dataset. Neurology, 82:S58.002, Published 2014. (Abstract)

499.   Deutsch MB, Mendez M, Teng E. The Association Between Frontotemporal Degeneration and Traumatic Brain Injury. Am J Neurodegener Dis, 3:189, Published 2014. (Abstract)

500.   Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Denning N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Schmidt H, Kunkle B, Dunstan ML, Vronskaya M, Johnson AD, Ruiz A, Bihoreau MT, Reitz C, Pasquier F, Hollingworth P, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Hernandez I, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fievet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, George-Hyslop PS, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossu P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Garcia FS, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Scarpini E, Bonuccelli U, Mancuso M, Siciliano G, Moebus S, Mecocci P, Zompo MD, Maier W, Hampel H, Pilotto A, Frank-Garcia A, Panza F, Solfrizzi V, Caffarra P, Nacmias B, Perry W, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH, Jr., Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nothen MM, Graff C, Psaty BM, Haines JL, Lathrop M, Pericak-Vance MA, Launer LJ, Van Broeckhoven C, Farrer LA, van Duijn CM, Ramirez A, Seshadri S, Schellenberg GD, Amouyel P, Williams J. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. PLoS One, 9:e94661, Published 2014, PMC4055488.

501.   Fargo KN, Aisen P, Albert M, Au R, Corrada MM, DeKosky S, Drachman D, Fillit H, Gitlin L, Haas M, Herrup K, Kawas C, Khachaturian AS, Khachaturian ZS, Klunk W, Knopman D, Kukull WA, Lamb B, Logsdon RG, Maruff P, Mesulam M, Mobley W, Mohs R, Morgan D, Nixon RA, Paul S, Petersen R, Plassman B, Potter W, Reiman E, Reisberg B, Sano M, Schindler R, Schneider LS, Snyder PJ, Sperling RA, Yaffe K, Bain LJ, Thies WH, Carrillo MC. 2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease. Alzheimers Dement, 10:S430-452, Published 2014.

502.   Fowler NR, Johnson KG, Lie J, Moore CG, Saba S, Lopez O, Barnato AE. Use of cardiac implantable electronic devices in older adults with cognitive impairment. JAMA Intern Med, 174:1514-1516, Published 2014, PMC4271315.

503.   Galkina E, Grinstein G. Comparison of interpolation methods for estimating spatially aggregated pollution exposure. 8th International Conference on Information Visualization, Paris, Accepted 2014. (Abstract)

504.   Galkina E, Grinstein G. Regional differences in diagnostic conversion to dementia. 8th International Conference on Information Visualization, Paris, Accepted 2014. (Abstract)

505.   Gaugler JE, Hovater M, Roth DL, Johnston JA, Kane RL, Sarsour K. Depressive, functional status, and neuropsychiatric symptom trajectories before an Alzheimer's disease diagnosis. Aging Ment Health, 18:110-116, Published 2014, PMC3855584.

506.   Gifford KA, Liu D, Jefferson AL. Source of cognitive complaint and neuropathology in mild cognitive impairment. Alzheimers Dement, (10)4 Supplement:P422-P423, Published 2014. (Abstract)

507.   Grill JD, Monsell S. Choosing Alzheimer's disease prevention clinical trial populations. Neurobiol Aging, 35:466-471, Published 2014, PMC3864603.

508.   Gross A, Sherva R, Mukherjee S, Newhouse S, Kauwe J, Munsie L, Waterston L, Bennett D, Jones R, Green R, Crane P, ADNI Collaborators, GENAROAD Collaborators, ADGC Collaborators. Calibrating longitudinal cognition in Alzheimer's disease across diverse test batteries and datasets. Neuroepidemiology, 43:194-205, Published 2014, PMC4297570.

509.   Gross AL, Mukherjee S, Sherva R, Newhouse S, Waterston LB, Jones RN, Green RC, Crane PK, ADNI Collaborators, GENAROAD Collaborators. Calibrating Longitudinal Cognitive Performance Across Diverse Neuropsychological Batteries and Datasets. Alzheimers Dement, 10:P746, Published 2014. (Abstract)

510.   Gu Y, Scarmeas N, Cosentino S, Brandt J, Albert M, Blacker D, Dubois B, Mayeux R, Stern Y. Change in Body Mass Index Before and After Alzheimer's Disease Onset. Curr Alzheimer Res, 11:349-356, Published 2014, PMC4026350.

511.   Haj-Hassan S, Hohman T, Liu D, Skinner J, Lu Z, Sparling J, Gifford K, Sumner E, Bell S, Jefferson A. A-28Vascular Risk and Cognitive Decline in Older Adults with and without Mild Cognitive Impairment (MCI). Arch Clin Neuropsychol, 29:513, Published 2014. (Abstract)

512.   Hao Y, Hameed S, Ting S. Clinicopathological Investigation of Psychosis in Alzheimer's disease using an Advanced Decision Tree Algorithm. SingHealth Duke-NUS Scientific Congress, Accepted 2014. (Abstract)

513.   Heller K, DeCarli C, Beekly D, Besser L, Bollenbeck M, Wu J, Carmichael O, Phelps C, Kukull W. The National Alzheimer's Coordinating Center MRI Database. Alzheimers Dement, 10:P833-834, Published 2014. (Abstract)

514.   Herberger V, Hodges EK, Giordani B, Zhu J, Dodge HH. Type 2 Diabetes Mellitus: Longitudinal Impact on Cognition in Persons with Normal Cognition, MCI, and Dementia. Alzheimers Dement, 10:P848, Published 2014. (Abstract)

515.   Hutchinson K, Dilks L, DuVall T. A-73Risk Factors for Apathy in Alzheimer's Disease. Arch Clin Neuropsychol, 29:530, Published 2014. (Abstract)

516.   Jefferson AL. Hemodynamic factors underlying the pathogenesis and clinical expression. J Int Neuropsychol Soc, 20:S36, Published 2014. (Abstract)

517.   Joshi A, Teng E, Tassniyom K, Mendez MF. Hippocampal and mesial temporal sclerosis in early-onset frontotemporal lobar degeneration versus Alzheimer's disease. Am J Alzheimers Dis Other Demen, 29:45-49, Published 2014, PMC3947801.

518.   Kauwe JS, Bailey MH, Ridge PG, Perry R, Wadsworth ME, Hoyt KL, Staley LA, Karch CM, Harari O, Cruchaga C, Ainscough BJ, Bales K, Pickering EH, Bertelsen S, Fagan AM, Holtzman DM, Morris JC, Goate AM, ADGC Collaborators. Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation. PLoS Genet, 10:e1004758, Published 2014, PMC4207667.

519.   Knopman D, Monsell S, Kukull W. US Alzheimer Centers' NACC FTLD Module: Initial Experience. International FTD Conference, Vancouver BC, Oct 24, Accepted 2014. (Abstract)

520.   Kolman S, Galkina E, Dufilie AS, Luo YF, Gupta V, Grinstein G. Linked visual analysis of structured datasets and document collections. Visualization and Data Analysis 2014 Proceedings of SPIE, Accepted 2014. (Abstract)

521.   Lane EM, Liu D, Xu M, Bell SP, Niswender KD, Jefferson AL. The Impact of Diabetes Medications on Alzheimer's Disease and Vascular Neuropathology. J Int Neuropsychol Soc, 20:S160, Published 2014. (Abstract)

522.   Leger GC, Banks SJ. Neuropsychiatric Symptom Profile Differs Based on Pathology in Patients with Clinically Diagnosed Behavioral Variant Frontotemporal Dementia.. Dement Geriatr Cogn Disord, 37:104-112, Published 2014, PMC4041327.

523.   Liu D, Skinner J, Gifford K, Jefferson AL. Biracial differences in the relation between vascular health and neuropathological markers of cerebrovascular disease and Alzheimer's disease. Alzheimers Dement, 10:P843, Published 2014. (Abstract)

524.   LoBue C, Lacritz L, Hart J, Jr., Kyle W, Cullum M. Self-Reported Head Injury and Earlier Age of Diagnosis of Mild Cognitive Impairment. Arch Clin Neuropsychol, 29:512, Published 2014. (Abstract)

525.   Logue MW, Schu M, Vardarajan BN, Farrell J, Bennett DA, Buxbaum JD, Byrd GS, Ertekin-Taner N, Evans D, Foroud T, Goate A, Graff-Radford NR, Kamboh MI, Kukull WA, Manly JJ.. Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans. Alzheimers Dement, 10:609-618, Published 2014, PMC4253055.

526.   Millikin C, Stoesz BM, Ismail Z, Fischer CE, Schweizer T. Factors Associated with Development and Stability of Delusions in Probable Alzheimer's Disease. Am J Geriatr Psychiatry, 22:S118-S119, Published 2014. (Abstract)

527.   Mioshi E, Knopman D. Dementia progression in FTLD differs markedly from AD: applicability of the CDR-FTLD in detecting change. 9th International Conference on Frontotemporal Dementias, Vancouver, Canada, Accepted 2014. (Abstract)

528.   Moga DC, Abner E, Jicha G. Bladder Antimuscarinics and Cognitive Decline in Elderly Patients Enrolled in the National Alzheimer's Coordinating Center Cohort. Pharmacoepidemiol Drug Saf, 23(S1):173-174, Published 2014. (Abstract)

529.   Moga DC, Abner E, Jicha G. Bladder Antimuscarinics Use by Older Women Enrolled in the National Alzheimer's Coordinating Center Cohort. Society for Epidemiologic Research Annual Meeting June 2014, Seattle, WA, Accepted 2014. (Abstract)

530.   Monsell SE, Besser LM, Heller KB, Checkoway H, Litvan I, Kukull WA. Clinical and pathologic presentation in Parkinson's disease by apolipoprotein e4 allele status. Parkinsonism Relat Disord, 20:503-507, Published 2014, PMC4028373.

531.   Monsell SE, Mock C, Hassenstab J, Roe CM, Cairns NJ, Morris JC, Kukull WK. Neuropsychological changes in asymptomatic persons with Alzheimer's disease neuropathology. Neurology, 83:434-440, Published 2014, PMC4132573.

532.   Monsell SE, Caselli RJ, Kukull WA, Beach TG, Montine TJ, Reiman EM. APOE4 non-carriers with the clinical diagnosis of Alzheimer's dementia and minimal amyloid histopathology. Alzheimers Dement, 10:P423, Published 2014. (Abstract)

533.   Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barnes LL, Beach TG, Becker JT, Beekly D, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carrasquillo MM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Dick M, Dickson DW, Duara R, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lin CF, Lopez OL, Lyketsos CG, Mack WJ, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Murrell JR, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Valladares O, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol, 71:1394-1404, Published 2014, PMC4314944.

534.   Nelson PT, Abner E, Kukull WA, Monsell SE, Ighodaro E, Fardo D. Association Between Hippocampal Sclerosis of Aging (HS-Aging) Pathology and Sulfonylurea Drug Exposure in NACC. J Neuropathol Exp Neurol, 73(6):619, Published 2014. (Abstract)

535.   Nelson PT, Estus S, Abner EL, Parikh I, Malik M, Neltner JH, Ighodaro E, Schellenberg GA, Wang WX, Wilfred BR, Kukull WA, Nandakumar K, Farman ML, Kofler JK, Poon WW, Corrada M, Kawas CH, Jicha GA, Hubbard RA, Bennett DA, Schneider JA, Sonnen JA, Crane PK, Wang LS, Cantwell L, Valladares O, Van Eldik L, Larson EB, Horbinski C, Green RC, Gearing M, Kramer PL, Woltjer RL, Wang X, Kamboh IM, Montine TJ, Partch AB, Oliver K, Monsell SE, ADGC Collaborators, Fardo DW. ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. Acta Neuropathol, 127:825-843, Published 2014, PMC4113197.

536.   Neltner JH, Abner EL, Baker S, Schmitt FA, Kryscio RJ, Jicha GA, Smith CD, Hammack E, Kukull WA, Brenowitz WD, Van Eldik LJ, Nelson PT. Arteriolosclerosis that affects multiple brain regions is linked to hippocampal sclerosis of ageing. Brain, 137:255-267, Published 2014, PMC3891448.

537.   Pandya SY, Clem MA, Horton DK, Lacritz LH, Cullum CM, Woon FL. Medication use as a predictor of reversion from mild cognitive impairment to normal cognition. 12th annual meeting of the American Academy of Clinical Neuropsychology, New York, NY, Accepted 2014. (Abstract)

538.   Pandya SY, Clem MA, Horton DK, Lacritz LH, Woon FL. Psychiatric symptoms in individuals reverting to normal cognition from mild cognitive impairment. 34th annual meeting of the National Academy of Neuropsychology, Puerto Rico, PR, Accepted 2014. (Abstract)

539.   Pillai JA, Bonner-Jackson A, Walker E, Mourany L, Cummings JL. Higher Working Memory Predicts Slower Functional Decline in Autopsy-Confirmed Alzheimer's Disease. Dement Geriatr Cogn Disord, 38:224-233, Published 2014, PMC4140977.

540.   Ringman JM, Sachs MC, Zhou Y, Monsell SE, Saver JL, Vinters HV. Clinical predictors of severe cerebral amyloid angiopathy and influence of APOE genotype in persons with pathologically-verified Alzheimer's disease. JAMA Neurol, 71:878-883, Published 2014, PMC4101018.

541.   Sadak TI, Katon J, Beck C, Cochrane BB, Borson S. Key neuropsychiatric symptoms in common dementias: prevalence and implications for caregivers, clinicians, and health systems. Res Gerongol Nurs, 7:44-52, Published 2014, PMC3909707.

542.   Sayegh P, Knight BG. Functional assessment and neuropsychiatric inventory questionnaires: measurement invariance across hispanics and non-Hispanic whites. Gerontologist, 54:375-386, Published 2014, PMC4031565.

543.   Sayegh P. The Role of Neuropsychological Language Tests in Clinician-rated Dementia Severity across Hispanics and Non-Hispanic Whites. International Neuropsychological Society 42nd Annual Meeting, Seattle, WA, Accepted 2014. (Abstract)

544.   Serrano-Pozo A, Qian J, Monsell SE, Blacker D, Gomez-Isla T, Betensky RA, Growdon JH, Johnson KA, Frosch MP, Sperling RA, Hyman BT. Mild to moderate Alzheimer dementia with insufficient neuropathological changes. Ann Neurol, 75:597-601, Published 2014, PMC4016558.

545.   Sherva R, Tripodis Y, Bennett DA, Chibnik LB, Crane PK, de Jager PL, Farrer LA, Saykin AJ, Shulman JM, Naj A, Green RC, ADGC Collaborators. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. Alzheimers Dement, 10:45-52, Published 2014, PMC3760995.

546.   Skinner J, Liu D, Xu M, Gifford K, Jefferson A. Stroke Risk Profile as a Predictor of Cognition in Minority Elders. J Int Neuropsychol Soc, 20:S90, Published 2014. (Abstract)

547.   Spiegel R, Berres M, Monsch A, Miserez A, Kukull WA. Validating the Placebo Group Simulation Approach (PGSA), an Alternative Study Design for Preventive Trials in Prodromal AD Patients. Alzheimers Dement, 10:P859, Published 2014. (Abstract)

548.   Steed D, Miller SA. Teasing Apart Concurrent and Predictive Influences on Dementia and Neuropsychiatric Symptoms. J Int Neuropsychol Soc, 20:S83, Published 2014. (Abstract)

549.   Tartaglia MC, Hu B, Mehta K, Neuhaus J, Yaffe K, Miller BL, Boxer A. Demographic and neuropsychiatric factors associated with off-label medication use in frontotemporal dementia and Alzheimer's disease. Alzheimer Dis Assoc Disord, 28:182-189, Published 2014, PMC3938980.

550.   Teng, YL. The Alzheimer's Disease Centers Uniform Data Set (UDS): Using various algorithms to predict Dementia types with MMSE and CDR NACC is funded by the National Institute on Aging (UO1 AG016976). Alzheimers Dement, 10:P676, Published 2014. (Abstract)

551.   Torralva T, Sposato L, Roca M, Gleichgerrcht E, Riccio PM, Hachinski V, Manes F. The Role of Cerebrovascular Disease in Behavioral Variant Frontotemporal Dementia. Am J Neurodegener Dis, 3(Suppl. 1), Published 2014. (Abstract)

552.   Tosto G, Monsell SE, Kukull WS, Mayeux R. Latent Analysis of Extrapyramidal Signs In Alzheimer Disease Identifies Distinct Disease Expressions. Alzheimers Dement, 10:P819, Published 2014. (Abstract)

553.   Weintraub S. Neuropsychological Profiles of Dementia: Neuroanatomical Networks Disorders. Seminar, McGill Center For Studies in Aging, December 12, 2014, Montreal, Quebec, Accepted 2014. (Abstract)

554.   Woodruff B, Hentz JG, Dueck AC, Locke DE, Stonnington CM, Wojtulewicz LB, Geda YE, Caselli RJ. Absence of a ”widowhood effect“ on incidence of dementia in cognitively normal research subjects. Alzheimers Dement, 10:P617-618, Published 2014. (Abstract)

555.   Woodruff B, Hentz JG, Dueck AC, Locke DE, Stonnington CM, Wojtulewicz LB, Geda YE, Caselli RJ. Paradoxical impact of widowhood on incidence of dementia in subjects with Mild Cognitive Impairment. Alzheimers Dement, 10:P617, Published 2014. (Abstract)

556.   Woon FL. Cognitive Predictors of Reversion to Normal Cognition from Mild Cognitive Impairment. Am Academy Clin N'psych 2014, Accepted 2014. (Abstract)

557.   Zhao M, Chan RHM, Chow TWS, Tang P. Compact Graph based Semi-Supervised Learning for Medical Diagnosis in Alzheimer's Disease. IEEE Signal Process Lett, 10:1192-1196, Published 2014, PMC5365156.

558.   Zhou X, Zhou C, Liu D, Ding X. Applied Missing Data Analysis in the Health Sciences (Statistics in Practice). In: Applied Missing Data Analysis in the Health Sciences (Statistics in Practice), Published 2014.

 
         2013
559.   Ascher-Svanum H, Gaugler J, Roth D, Fafowora T, Siderowf A, Beach T. Characteristics of Patients Misdiagnosed with Alzheimer's Disease and Their Medication Use: An Analysis of the NACC-UDS Database. Alzheimers Dement, 9:P734, Published 2013. (Abstract)

560.   Ayutyanont N, Langbaum JBS, Hendrix SB, Fleisher AS, Caselli R, Monsell SE, Chen K, Kukull WA, Bennett D, Tariot PN, Reiman EM. Validation of the Alzheimer's Prevention Initiative Composite Cognitive Test Score. Alzheimers Dement, 9:P320, Published 2013. (Abstract)

561.   Besser LM, Gill DP, Monsell SE, Brenowitz W, Meranus D, Gustafson D, Kukull W. Body Weight Change and Clinical Progression in Mild Cognitive Impairment and Alzheimer's Disease. Neurodegener Dis, 11(S1), Published 2013. (Abstract)

562.   Besser LM, Hawes SE, Bristow KE, Monsell SE, Kukull WA. Pulse Pressure and Atherosclerosis, Arteriolosclerosis, and Cortical Microinfarcts in Individuals with Clinical Alzheimer's Disease.. Alzheimers Dement, 9:P441, Published 2013. (Abstract)

563.   Brenowitz WD, Monsell SE, Kukull WA, Nelson PT. Hippocampal sclerosis of aging, a key potential AD confounder: the NACC experience. Alzheimers Dement, 9:P542, Published 2013. (Abstract)

564.   Brenowitz WD, Nelson PT, Besser LM, Bristow KE, Kukull WA. Cerebral Amyloid Angiopathy and its Co-occurrence with Alzheimer's Disease in the National Alzheimer's Coordinating Center Neuropathology Data Set. Alzheimers Dement, 9:P433, Published 2013. (Abstract)

565.   Bristow KE, Besser LM, Monsell SE, Brenowitz W, Hawes SE, Kukull WA. Consensus Diagnosis and Predictors of Diagnostic Accuracy in the National Alzheimer's Disease Centers. Alzheimers Dement, 9:P321, Published 2013. (Abstract)

566.   Bruns M, Bristow K, Monsell SE, Aakre J, Kukull W, Pankratz V, Knopman D, Graff-Radford N, Miller B, Laden F, Dickinson S, Mesulam M, Boeve B. Similar maximal educational attainment in people with dementia: Association with pathologically diagnosed frontotemporal lobar degeneration, Alzheimer's disease and Lewy body disease?. Alzheimers Dement, 9:P631, Published 2013. (Abstract)

567.   Bruns M, Pankratz VS, Wicklund M, Kukull W, Knopman D, Graff-Radford N, Miller B, Laden F, Mesulam MM, Boeve B. Educational Attainment in Patients with Frontotemporal Dementia and Primary Progressive Aphasia Compared to Other Dementia Syndromes. Neurology, 80:P03.089, Published 2013. (Abstract)

568.   Chen B, Zhou A. A Correlated Random Effects Model for Non-homogeneous Markov Process with Nonignorable Missingness. J Multivar Anal, 117:41287, Published 2013, PMC3697104.

569.   Chen B, Zhou A. Generalized Partially Linear Models for Incomplete Longitudinal Data In the Presence of Population-Level Information. Biometrics, 69:386-395, Published 2013, PMC3715115.

570.   Chen B, Qin J. A new estimation with minimum trace of asymptotic covariance matrix for incomplete longitudinal data with a surrogate process. Stat Med, 32:4763-4780, Published 2013, PMC3808493.

571.   Cheng Y, Trzepacz PT, Chang C, Hake AM, Siemers ER. Seizure and associated factors in patients with different types of dementia. Pharmacoepidemiol Drug Saf, 22(S1):266, Published 2013. (Abstract)

572.   Cocroft S. Alzheimer's Disease and African Americans. North Central Sociological Association's annual meeting, Accepted 2013. (Abstract)

573.   Cosentino S, Schupf N, Christensen K, Anderson S, Newman A, Mayeux R. Reduced Prevalence of Cognitive Impairment in Families With Exceptional Longevity. JAMA Neurol, 70:867-874, Published 2013, PMC4151346.

574.   Cruchaga C, Kauwe JS, Harari O, Jin SC, Cai Y, Karch CM, Benitez BA, Jeng AT, Skorupa T, Carrell D, Bertelsen S, Bailey M, McKean D, Shulman JM, De Jager PL, Chibnik L, Bennett DA, Arnold SE, Harold D, Sims R, Gerrish A, Williams J, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Peskind ER, Galasko D, Fagan AM, Holtzman DM, Morris JC, ADGC Collaborators, Goate AM. GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron, 78:256-268, Published 2013, PMC3664945.

575.   Dams-O'Connor K, Spielman L, Hammond FM, Sayed N, Culver C, Diaz-Arrastia R. An exploration of clinical dementia phenotypes among individuals with and without traumatic brain injury. NeuroRehabilitation, 32:199-209, Published 2013, PMC3767178.

576.   De Felipe J, Benson G, Luo X, Sewell M, Sano M. Performance of Spanish Speaking Community dwelling elders in the US on the Uniform Data Set (UDS). Alzheimers Dement, 9:P621-623, Published 2013. (Abstract)

577.   Fowler NR, Sarles CE, Li J, Barnato AE. Prevalence and incidence of cardiac devices in a national Alzheimer's Disease Centers sample. J Am Geriatr Soc, 61:S106-107, Published 2013. (Abstract)

578.   Fowler NR. Decision quality and the use of cardiac rhythm regulating devices in adults with cognitive impairment. Alzheimers Dement, 9:P634, Published 2013. (Abstract)

579.   Galkina E, Purushe S, Grinstein GG.. Feasibility of pattern discovery in modeling cognitive decline in Alzheimer's disease using the Weave platform. VizBi Conference Cambridge MA, Accepted 2013. (Abstract)

580.   Gaugler JE, Ascher-Svanum H, Roth DL, Fafowora T, Siderowf A, Beach TG. Characteristics of patients misdiagnosed with alzheimer's disease and their medication use: an analysis of the NACC-UDS database. BMC Geriatrics, 13:137, Published 2013, PMC3878261.

581.   Gill DP, Hubbard RA, Koepsell TD, Borrie M, Petrella RJ, Knopman D, Kukull WA. Differences in rate of functional decline across three dementia types. Alzheimers Dement, 9:S63-71, Published 2013, PMC3766452.

582.   Giraldo M, Lopera F, Siniard AL, Corneveaux JJ, Schrauwen I, Carvajal J, Munoz C, Ramirez-Restrepo M, Gaiteri C, Myers AJ, Caselli RJ, Kosik KS, Reiman EM, Huentelman MJ. Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease. Neurobiol Aging, 34:2077 e11-8, Published 2013, PMC3830921.

583.   Goldstein FC, Levey AI, Steenland NK. High blood pressure and cognitive decline in mild cognitive impairment. J Am Geriatr Soc, 61:67-73, Published 2013, PMC3699694.

584.   Grill JD, Monsell S. Choosing Alzheimer's disease prevention trial populations. J Nutr Health Aging, 17:815-816, Published 2013. (Abstract)

585.   Gross A, Sherva R, Mukherjee S, Newhouse S, Waterston L, Zavitz K, Bennett D, Jones R, Crane P, Green R, ADNI, GENAROAD. Calibration of a new approach for estimating general cognitive performance for GWAS of cognitive decline in Alzheimer's disease. Alzheimers Dement, 9:P697-698, Published 2013. (Abstract)

586.   Gross AL, Sherva R, Mukherjee SR, Newhouse S, Kauwe J, Saykin AJ, Bennett DA, Chibnik LB, Kraft P, Crane PK, Green RC. Genome-Wide Association Study of Rate of Cognitive Decline in Six Cohorts with Patients with Alzheimer's Disease. 66th GSA Annual Scientific Meeting, New Orleans, LA, Accepted 2013. (Abstract)

587.   Gross AL, Sherva R, Mukherjee SR, Newhouse S, Waterston LB, Mungas DM, Green RC, Jones RN, Crane PK. Novel Approach for Calibrating Longitudinal Cognitive Performance in Older Adults. 66th GSA Annual Scientific Meeting, New Orleans, LA, Accepted 2013. (Abstract)

588.   Gu Y, Scarmeas N, Cosentino S, Brandt J, Albert M, Blacker D, Dubois B, Mayeux R, Stern Y. Body Mass Change in Alzheimer's Disease. Alzheimers Dement, 9:P206-207, Published 2013. (Abstract)

589.   Hart KR, Hanfelt JJ. Robust Latent Class Analysis for Longitudinal Data. Joint Statistical Meeting (JSM) Montreal, Canada, Accepted 2013. (Abstract)

590.   Hayden KM, Kuchibhatla M, Plassman BL, Germain CM, Romero HR, Welsh-Bohmer KA. The Use of Reliable Change Indices to Complement Norms in the Early Identification of Cognitive Decline. Alzheimers Dement, 9:P535-536, Published 2013. (Abstract)

591.   Holton P, Ryten M, Nalls M, Trabzuni D, Weale ME, Hernandez D, Crehan H, Gibbs JR, Mayeux R, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD, Ramirez-Restrepo M, Engel A, Myers AJ, Corneveaux JJ, Huentelman MJ, Dillman A, Cookson MR, Reiman EM, Singleton A, Hardy J, Guerreiro R, ADGC Collaborators. Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci. Ann Hum Genet, 77:85-105, Published 2013, PMC3578142.

592.   Hsiao JJ, Lee GJ, Lu PH, Teng E. Longitudinal declines in instrumental activities of daily living in stable and progressive mild cognitive impairment. Neurology, 80:P07.154, Published 2013. (Abstract)

593.   Hutchinson KS. Risk factors for apathy in Alzheimer's disease. Doctoral Dissertation, Fielding Graduate University, Defended 2013.

594.   Jicha G, Nelson P, Fardo D, Kryscio R, Schmitt F, Smith C, Neltner J, Van Eldik L, Kukull W, Abner E. Vascular neuropathology in dementia patients receiving antipsychotic therapy. Alzheimers Dement, 9:P303, Published 2013. (Abstract)

595.   Joshi A, Teng E, Tassniyom K, Shapira JS, Mendez MF. Hippocampal and medial temporal sclerosis in behavioral variant frontotemporal dementia. Neurology, 80:S44.007, Published 2013. (Abstract)

596.   Kalapatapu RK, Delucchi KL. APOE e4 genotype and cigarette smoking in adults with normal cognition and mild cognitive impairment: a retrospective baseline analysis of a national dataset. Am J Drug Alcohol Abuse, 39:219-226, Published 2013, PMC3710309.

597.   Kaur B, Harvey DJ, DeCarli CS, Zhang L, Sabbagh MN, Olichney JM. Extrapyramidal signs by dementia severity in Alzheimer disease and dementia with Lewy bodies. Alzheimer Dis Assoc Disord, 27:226-232, Published 2013, PMC3562426.

598.   Khachaturian AS, Meranus DH, Kukull WA, Khachaturian ZS. Big data, aging, and dementia: pathways for international harmonization on data sharing. Alzheimers Dement, 9:S61-62, Published 2013.

599.   Koepsell TD, Gill DP, Chen B. Stability of Clinical Etiologic Diagnosis in Dementia and Mild Cognitive Impairment: Results from a Multi-Center Longitudinal Database. Am J Alzheimers Dis Other Demen, 28:750-758, Published 2013, PMC3876285.

600.   Kremen S, Tassniyom K, Mendez M, Teng E. Extrapyramidal Signs in Primary Progressive Aphasia: Analyses of the NACC UDS Cohort. Neurology, 80:P06.071, Published 2013. (Abstract)

601.   Kukull W, Monsell S, Besser L, Bristow K, Beekly D, Mock C, Hawes H. Comparison of Motor Symptoms in MCI by Underlying Disease Process. Neurodegener Dis, 11(S1), Published 2013. (Abstract)

602.   Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, Jun G, Destefano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Hollingworth P, Ramirez A, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Moron FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fievet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossu P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F, Moebus S, Mecocci P, Del Zompo M, Maier W, Hampel H, Pilotto A, Bullido M, Panza F, Caffarra P, Nacmias B, Gilbert JR, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH, Jr., Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Wang LS, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nothen MM, Graff C, Psaty BM, Jones L, Haines JL, Holmans PA, Lathrop M, Pericak-Vance MA, Launer LJ, Farrer LA, van Duijn CM, Van Broeckhoven C, Moskvina V, Seshadri S, Williams J, Schellenberg GD, Amouyel P. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet, 45:1452-1458, Published 2013, PMC3896259.

603.   Lane EM, Liu D, Lu Z, Niswender KD, Jefferson AL. The Differential Impact of Diabetes Medications on Cognition. Alzheimers Dement, 9:P206, Published 2013. (Abstract)

604.   Li B, Chow TWS, Huang D. A novel feature selection method and its application. J Intell Inf Syst, 41:235-268, Published 2013, PMC4269276.

605.   Liu D, Zhou A. ROC Analysis in Biomarker Combination with Covariate Adjustment. Acad Radiol, 20:874-882, Published 2013, PMC3682803.

606.   Liu D, Zhou XH. Covariate adjustment in estimating the area under ROC curve with partially missing gold standard. Biometrics, 69:91-100, Published 2013, PMC3622116.

607.   Liu W, Zhang B, Zhang Z, Zhou XH. Joint Modeling of Transitional Patterns of Alzheimer's Disease. PLoS One, 8:e75487, Published 2013, PMC3779177.

608.   Macklin EA, Blacker D, Hyman BT, Betensky RA. Improved Design of Prodromal Alzheimer's Disease Trials through Cohort Enrichment and Surrogate Endpoints. J Alzheimers Dis, 36:475-486, Published 2013, PMC3779898.

609.   McDavid A, Crane PK, Newton KM, Crosslin DR, McCormick W, Weston N, Ehrlich K, Hart E, Harrison R, Kukull WA, Rottscheit C, Peissig P, Stefanski E, McCarty CA, Zuvich RL, Ritchie MD, Haines JL, Denny JC, Schellenberg GD, de Andrade M, Kullo I, Li R, Mirel D, Crenshaw A, Bowen JD, Li G, Tsuang D, McCurry S, Teri L, Larson EB, Jarvik GP, Carlson CS. Enhancing the Power of Genetic Association Studies through the Use of Silver Standard Cases Derived from Electronic Medical Records. PLoS One, 8:e63481, Published 2013, PMC3677889.

610.   Mendez MF, Joshi A, Tassniyom K, Teng E, Shapira JS. Clinicopathological Differences Among Patients with Clinical Behavioral Variant Frontotemporal Dementia. Neurology, 80:561-568, Published 2013, PMC3589292.

611.   Meranus D, Kukull W. Antithrombotic medication use and dementia incidence in a longitudinal cohort with mild cognitive impairment and atrial fibrillation. Alzheimers Dement, 9:P612, Published 2013. (Abstract)

612.   Mez J, Cosentino S, Brickman AM, Huey ED, Manly JJ, Mayeux R. Dysexecutive versus amnestic Alzheimer disease subgroups: analysis of demographic, genetic, and vascular factors. Alzheimer Dis Assoc Disord, 27:218-225, Published 2013, PMC3748394.

613.   Mez J, Cosentino S, Brickman AM, Huey ED, Manly JJ, Mayeux R. Faster cognitive and functional decline in Dysexecutive versus amnestic Alzheimer's subgroups: a longitudinal analysis of the National Alzheimer's Coordinating Center (NACC) database. PLoS One, 8:e65246, Published 2013, PMC3670903.

614.   Mez J, Cosentino S, Brickman AM, Huey ED, Mayeux R. Different demographic, genetic, and longitudinal traits in language versus memory Alzheimer's disease subgroups. J Alzheimers Dis, 37:137-146, Published 2013, PMC3877683.

615.   Miyashita A, Koike A, Jun G, Wang LS, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Ikeuchi T, Nishizawa M, Suga M, Kawase Y, Akatsu H, Kosaka K, Yamamoto T, Imagawa M, Hamaguchi T, Yamada M, Moriaha T, Takeda M, Takao T, Nakata K, Fujisawa Y, Sasaki K, Watanabe K, Nakashima K, Urakami K, Ooya T, Takahashi M, Yuzuriha T, Serikawa K, Yoshimoto S, Nakagawa R, Kim JW, Ki CS, Won HH, Na DL, Seo SW, Mook-Jung I, St George-Hyslop P, Mayeux R, Haines JL, Pericak-Vance MA, Yoshida M, Nishida N, Tokunaga K, Yamamoto K, Tsuji S, Kanazawa I, Ihara Y, Schellenberg GD, Farrer LA, Kuwano R. SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. PLoS One, 8:e58618, Published 2013, PMC3614978.

616.   Monsell SE, Mock C, Roe CM, Ghoshal N, Morris JC, Cairns NJ, Kukull W. Comparison of symptomatic and asymptomatic persons with Alzheimer's disease neuropathology. Neurology, 80:2121-2129, Published 2013, PMC3716351.

617.   Monsell SM, Bristow KE, Besser LM, Checkoway H, Litvan I, Kukull WA. APOE e4 and clinical progression in Parkinson's disease. Alzheimers Dement, 9:P738-739, Published 2013. (Abstract)

618.   Obermann KR, Morris JC, Roe CM. Exploration of 100 commonly used drugs and supplements on cognition in older adults. Alzheimers Dement, 9:724-732, Published 2013, PMC3823812.

619.   Piper BJ, Yasen AL, Taylor AE, Ruiz JR, Gaynor JW, Dayger CA, Gonzalez-Gross M, Kwon OD, Nilsson LG, Day IN, Raber J, Miller JK. Non-replication of an association of Apolipoprotein E2 with sinistrality. Laterality, 18:251-261, Published 2013, PMC3770935.

620.   Qiu WQ, Mwamburi M, Besser LM, Zhu H, Li H, Wallack M, Phillips L, Qiao L, Budson AE, Stern R, Kowall N. Angiotensin Converting Enzyme Inhibitors and the Reduced Risk of Alzheimer's disease in the Absence of Apoliprotein E4 allele. J Alzheimers Dis, 37:421-428, Published 2013, PMC3873370.

621.   Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith P, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hendrie H, Hall KS, Goate AM, Byrd GS, Kukull WA, Foroud TM, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD, Mayeux R, ADGC Collaborators. Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E 4,and the risk of late-onset Alzheimer disease in African Americans. JAMA, 309:1483-1492, Published 2013, PMC3667653.

622.   Reitz C, Mayeux R, ADGC Collaborators. TREM2 and neurodegenerative disease. N Engl J Med, 369:1564-1565, Published 2013, PMC3980568.

623.   Reitz C, Tosto G, Vardarajan B, Rogaeva E, Ghani M, Rogers RS, Conrad C, Haines JL, Pericak-Vance MA, Fallin MD, Foroud T, Farrer LA, Schellenberg GD, George-Hyslop PS, Mayeux R, ADGC Collaborators. Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP). Transl Psychiatry, 3:e256, Published 2013, PMC3669917.

624.   Ridge PG, Mukherjee S, Crane P, Kauwe JSK, ADGC Collaborators. Alzheimer's Disease: Analyzing the Missing Heritability. PLoS One, 8:e79771, Published 2013, PMC3820606.

625.   Rosenberg PB, Mielke MM, Appleby BS, Oh ES, Geda YE, Lyketsos CG. The Association of Neuropsychiatric Symptoms in MCI with Incident Dementia and Alzheimer's Disease. Am J Geriatr Psychiatry, 21:685-695, Published 2013, PMC3428504.

626.   Sachs MC, Zhou XH. Partial summary measures of the predictiveness curve. Biom J, 55:589-602, Published 2013, PMC3806283.

627.   Sayed N, Culver C, Dams-O'Connor K, Hammond F, Diaz-Arrastia R. Clinical phenotype of dementia after traumatic brain injury. J Neurotrauma, 30:1117-1122, Published 2013, PMC3705947.

628.   Sayegh P, Knight BG. Assessment and diagnosis of dementia in Hispanic and non-Hispanic white outpatients. Gerontologist, 53:760-769, Published 2013, PMC3771673.

629.   Serrano-Pozo A, Qian J, Monsell SE, Frosch MP, Betensky RA, Hyman BT. Examination of the clinicopathologic continuum of Alzheimer disease in the autopsy cohort of the National Alzheimer Coordinating Center. J Neuropathol Exp Neurol, 72:1182-1192, Published 2013, PMC3962953.

630.   Sherva R, Gross AL, Mukherjee SR, Newhouse S, Kauwe J, Munsie L, Saykin AJ, Bennett DA, Chibnik LB, DeJager P, Kraft P, Crane PK, Green RC. GWAS of Rate of Cognitive Decline in Six AD Cohorts. 63rd Annual Meeting of The American Society of Human Genetics, Boston MA, Accepted 2013. (Abstract)

631.   Shim YS, Roe CM, Buckles VD, Morris JC. Clinicopathologic Study of Alzheimer's Disease: Alzheimer Mimics. J Alzheimers Dis, 35:799-811, Published 2013, PMC3725959.

632.   Spackman DE, Kadiyala S, Neumann PJ, Veenstra DL, Sullivan SD. The Validity of Dependence as a Health Outcome Measure in Alzheimer's Disease. Am J Alzheimers Dis Other Demen, 28:245-252, Published 2013, PMC3690581.

633.   Steenland K, Zhao L, Goldstein FC, Levey A. Statins and cognitive decline in older adults with normal cognition or mild cognitive impairment. J Am Geriatr Soc, 61:1449-1455, Published 2013, PMC3773248.

634.   Thambisetty M, An Y, Tanaka T. Alzheimer's disease risk genes and the age-at-onset phenotype. Neurobiol Aging, 34:2696.e1-2696.e5, Published 2013, PMC4038407.

635.   Toledo JB, Arnold SE, Brettschneider J, Lee EB, Xie SX, Grossman M, Monsell SM, Kukull WA, Trojanowski JQ. Importance of coincident neurodegenerative diseases. Alzheimers Dement, 9:P334, Published 2013. (Abstract)

636.   Toledo JB, Arnold SE, Raible K, Brettschneider J, Xie SX, Grossman M, Monsell SE, Kukull WA, Trojanowski JQ. Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer's Coordinating Centre. Brain, 136:2697-2706, Published 2013, PMC3858112.

637.   Trzepacz PT, Saykin A, Yu P, Bhamditipati P, Sun J, Dennehy EB, Willis B, Cummings JL. Subscale validation of the neuropsychiatric inventory questionnaire: comparison of Alzheimer's disease neuroimaging initiative and national Alzheimer's coordinating center cohorts. Am J Geriatr Psychiatry, 21:607-622, Published 2013, PMC3913908.

638.   Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA, Kramer P, Woltjer R, Trojanowski JQ, Weintraub D, Chen-Plotkin AS, Irwin DJ, Rick J, Schellenberg GD, Watson S, Kukull W, Nelson PT, Jicha GA, Neltner JH, Galasko D, Masliah E, Quinn JF, Chung KA, Yearout D, Mata IF, Wan JY, Edwards KL, Montine TJ, Zabetian CP. APOE ε4 Increases Risk for Dementia in Pure Synucleinopathies. JAMA Neurol, 70:223-228, Published 2013, PMC3580799.

639.   Wallack M, Zhu H, Mwamburi M, Phillips LE, Budson A, Kowall N, Stern R, Qiu WQ. Apolipoprotein E Allele, Angiotensin-Converting Enzyme and its inhibitors, in the Development of Alzheimer's Disease. Alzheimers Dement, 9:P616-617, Published 2013. (Abstract)

640.   Wang L, Zhou X-H. Causal Inference with Truncation by Death in Observational Study. The Western North American Region of the International Biometric Society Annual Meeting, Los Angeles, CA, Accepted 2013. (Abstract)

641.   Wang L, Zhou XH, Kukull W. Are some individuals immune to dementia?. Alzheimers Dement, 9:P617-618, Published 2013. (Abstract)

642.   Wang Z, Zhou A. Latent class regression model for assessment of diagnostic tests in the absence of a gold standard, with accommodation for covariate information. Joint Statistical Meeting Montreal, Canada, Accepted 2013. (Abstract)

643.   Wangoria E, Wordoffa H. Alzheimer's Disease Stage Prediction using Machine Learning and Multi Agent System. Thesis, Blekinge Inst of Tech, School of Computing, Defended 2013.

644.   Wyman-Chick K. Clinical Utility of the Clinical Dementia Rating Scale for Parkinson's Disease Dementia. A Dissertation Submitted to the Faculty of the School of Professional Psychology, Pacific Univeristy, Hillsboro, Oregon, Defended 2013.

645.   Xie Y, Zimmerman DL. Antedependence models for nonstationary categorical longitudinal data with ignorable missingness: likelihood-based inference. Stat Med, 32:3274-3289, Published 2013, PMC3885186.

646.   Zhao MB, Chan RHM, Tang P, Chow TWS, Wong SWH. Trace Ratio Linear Discriminant Analysis for Medical Diagnosis: A Case Study of Dementia. IEEE Signal Process Lett, 20:431-434, Published 2013, PMC3784002.

647.   Zhu JY, Vandermorris S, Craik FIM. Digit Symbol Substitution as a Marker of Asymptomatic AD. J Int Neuropsychol Soc, 19(S1):222, Published 2013. (Abstract)

 
         2012
648.   Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N.. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology, 79:221-228, Published 2012, PMC3398432.

649.   Banks S, Leger G. Neuropsychiatric symptom profile differs based on pathology in patients with clinically diagnosed frontotemporal dementia. Dement Geriatr Cogn Disord, 34 (Suppl 1):213, Published 2012. (Abstract)

650.   Beach T, Monsell S, Phillips L, Kukull W. Accuracy of the Clinical Diagnosis of Alzheimer's Disease at National Institute on Aging Alzheimer's Disease Centers, 2005-2010. J Neuropathol Exp Neurol, 71:266-273, Published 2012, PMC3331862.

651.   Beekly D, Monsell S, Besser L, Gill D, Robichaud E, Knopman D, Kukull W. The NACC FTLD Module data. Dement Geriatr Cogn Disord, 34 (Suppl 1), Published 2012. (Abstract)

652.   Besser LM, Monsell S, Kukull WA. Comparison of Neuropsychological Test Scores among English and Spanish Speakers in a Multi-regional Sample of Cognitively Normal Subjects. Alzheimers Dement, 8:P548, Published 2012. (Abstract)

653.   Bhatta R, Chou SY, Cantwell L, Schellenberg G, Wang LS. Alzheimer's Disease and toxicity exposure: a gene-environment interactions analysis. American Society for Health Economics Conference Minneapolis, MN June, Accepted 2012. (Abstract)

654.   Brenowitz W, Monsell S, Gill D, Kukull W. Neuropsychiatric symptoms in mild Alzheimer's disease: the influence of research study informants. Alzheimers Dement, 8:P382-P383, Published 2012. (Abstract)

655.   Chen B, Zhou A. A Latent-Variable Marginal Method for Multi-Level Incomplete Binary Data. Stat Med, 31:3211-3222, Published 2012, PMC3631603.

656.   Chen B, Yi G, Cook R, Zhou XH. Marginal Methods for Clustered Longitudinal Binary Data with Incomplete Covariates. J of Stat Plan Inference, 142:2819-2831, Published 2012, PMC3690662.

657.   Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, Cotman CW, Decarli CS, Levey AI, Ringman JM, Mendez MF, Chui HC, Le Ber I, Brice A, Lupton MK, Preza E, Lovestone S, Powell J, Graff-Radford N, Petersen RC, Boeve BF, Lippa CF, Bigio EH, Mackenzie I, Finger E, Kertesz A, Caselli RJ, Gearing M, Juncos JL, Ghetti B, Spina S, Bordelon YM, Tourtellotte WW, Frosch MP, Vonsattel JP, Zarow C, Beach TG, Albin RL, Lieberman AP, Lee VM, Trojanowski JQ, Van Deerlin VM, Bird TD, Galasko DR, Masliah E, White CL, Troncoso JC, Hannequin D, Boxer AL, Geschwind MD, Kumar S, Mandelkow EM, Wszolek ZK, Uitti RJ, Dickson DW, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, ADGC Collaborators, Ross OA, Rademakers R, Schellenberg GD, Miller BL, Mandelkow E, Geschwind DH. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet, 21:3500-3512, Published 2012, PMC3392107.

658.   Gavett BE. Dementia has a Categorical, not Dimensional, Latent Structure. Psychol Aging, 27:791-797, Published 2012, PMC3445289.

659.   Gill DP, Hubbard RA, Koepsell TD, Knopman DS, Kukull WA. Sex differences in rate of progression of three dementia types. Alzheimers Dement, 8:P622-P623, Published 2012. (Abstract)

660.   Grill JD, Monsell S, Karlawish J. Are patients whose study partners are spouses more likely to be eligible for Alzheimer's disease clinical trials?. Dement Geriatr Cogn Disord, 33:334-340, Published 2012, PMC3477789.

661.   Gustafson DR, Gill DP, Monsell SE. Evaluating sex differences and vascular morbidities in relation to global cognitive function in incident Alzheimer's disease. Alzheimers Dement, 8:P496, Published 2012. (Abstract)

662.   Hajjar I, Brown L, Mack W, Chui H. Impact of angiotensin receptor blockers on Alzheimer's disease neuropathology in a large brain autopsy series. Arch Neurol, 69:1632-1638, Published 2012, PMC3608189.

663.   Hyman BT, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Carrillo MC, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Thies B, Trojanowski JQ, Vinters HV, Montine TJ. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimers Dement, 8:1-13, Published 2012, PMC3266529.

664.   Jefferson AL, Sparling J, Gifford K, Cantwell N, Martin B, Tripodis Y. An elevated vascular health index is related to worse cognitive performance in individuals with mild cognitive impairment. Int'l Neuropsychological Society Meeting, Published 2012. (Abstract)

665.   Jun G, Vardarajan BN, Buros J, Yu CE, Hawk MV, Dombroski BA, Crane PK, Larson EB. Comprehensive search for Alzheimer disease susceptibility loci in the APOE region. Arch Neurol, 69:1270-1279, Published 2012, PMC3579659.

666.   Knopman D, Weintraub S, Pankratz VS. Augmented (8-item) Clinical Dementia Rating Scale is an effective instrument for longitudinal studies of bvFTD and PPA. Dement Geriatr Cogn Disord, 34 (Suppl 1):21-22, Published 2012. (Abstract)

667.   Koepsell TD, Monsell SE. Reversion from mild cognitive impairment to normal or near-normal cognition: risk factors and prognosis. Neurology, 79:1591-1598, Published 2012, PMC3475624.

668.   Kukull WA, Ganguli M. Generalizability: The trees, the forest, and the low-hanging fruit. Neurology, 78:1886-1891, Published 2012, PMC3369519.

669.   Kukull WA. An apple a day to prevent Parkinson disease: reduction of risk by flavonoids. Neurology, 78:1112-1113, Published 2012.

670.   Kukull W, Knopman D, Mesulam M, Grossman M, Miller B, Weintraub S, Kramer J, Rankin K, Rosen H, Hillis A, Boeve B, Mendez M, Phelps C, Morris J. Standardized data collection and diagnostic formulation for FTLD Clinical Exam: The FTLD Module. Dement Geriatr Cogn Disord, 34 (Suppl 1), Published 2012. (Abstract)

671.   Lee GJ, Elashoff D, Di LJ, Teng E, Melchor S, Lu PH. Age-Associated Memory Impairment Increases Risk of Conversion to MCI and Dementia. Alzheimers Dement, 8:P544, Published 2012. (Abstract)

672.   Mendez M, Joshi A, Tassniyom K, Teng E. Clinicopathological differences among patients meeting clinical criteria for behavioral variant frontotemporal dementia. Dement Geriatr Cogn Disord, 34 (Suppl 1):260-261, Published 2012. (Abstract)

673.   Meranus D, Monsell S, Thomas G, Kukull W. Cholinesterase Inhibitors and Memantine Use in the National Alzheimer's Coordinating Center's Uniform Data Set: A Longitudinal Assessment of Real-World Medication Use in Dementia. Alzheimers Dement, 8:P711, Published 2012. (Abstract)

674.   Mez J, Consentino S, Brickman A, Huey E, Manley J, Mayeux R. Cognitive and functional decline in dysexecutive versus amnestic Alzheimer's. Alzheimers Dement, 8:P635-P636, Published 2012. (Abstract)

675.   Mez J, Cosentino S, Brickman A, Huey E, Manly J, Mayeux R. Characterization of Dysexecutive Versus Amnestic Alzheimer's Disease Phenotypes in the National Alzheimer's Coordinating Center (NACC) Database. Neurology, 78(S), Published 2012. (Abstract)

676.   Monsell SE, Liu D, Weintraub S, Kukull WA. Comparing measures of decline to dementia in amnestic MCI subjects in the National Alzheimer's Coordinating Center (NACC) Uniform Data Set. Int Psychogeriatr, 24:1553-1560, Published 2012, PMC3614357.

677.   Montine TJ, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Trojanowski JQ, Vinters HV, Hyman BT. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach. Acta Neuropathol, 123:1-11, Published 2012, PMC3268003.

678.   Morris JC. Revised criteria for Mild Cognitive Impairment may compromise the diagnosis of Alzheimer Disease dementia. Arch Neurol, 69:700-708, Published 2012, PMC3423496.

679.   Nandipati S, Luo X, Schimming C, Grossman H, Sano M. Cognition in Non-Demented Diabetic Older Adults. Curr Aging Sci, 5:131-135, Published 2012, PMC3659164.

680.   Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, Hyman BT, Iwatsubo T, Jellinger KA, Jicha GA, Kovari E, Kukull WA, Leverenz JB, Love S, Mackenzie IR, Mann DM, Masliah E, McKee AC, Montine TJ, Morris JC, Schneider JA, Sonnen JA, Thal DR, Trojanowski JQ, Troncoso JC, Wisniewski T, Woltjer RL, Beach TG. Correlation of Alzheimer's Disease Neuropathologic Changes with Cognitive Status: a Review of the Literature. J Neuropathol Exp Neurol, 71:362-381, Published 2012, PMC3560290.

681.   Olchanski N, Lin PJ, Cohen JT, Neumann PJ. Alzheimer's disease progression rates: new estimates. American Neurological Association Annual Meeting in Boston, MA, Oct 8, Accepted 2012. (Abstract)

682.   Pirraglia E, Lobach I, De Santi S, Karantzoulis S, Glodzik L, de Leon MJ. A Comparison of Methods for Deriving Normative Scores for Evaluating Cognitive Impairment. Alzheimers Dement, 8:P541-P542, Published 2012. (Abstract)

683.   Pirraglia E, Murray J, De Santi S, Mosconi L, Glodzik L, de Leon MJ. Maternal History and Impaired Memory Predicts Future Decline to Dementia in Cognitively Normal Individuals. Alzheimers Dement, 8:P542, Published 2012. (Abstract)

684.   Sadak T, Katon J, Borson S. Defining Dementia Multimorbidity in a National Sample. J Am Geriatr Soc, 60:S62, Published 2012. (Abstract)

685.   Sadak T, Katon J, Borson S. Multimorbidity in Alzheimer's Disease and Related Dementias. Alzheimers Dement, 8:P490-P491, Published 2012. (Abstract)

686.   Sadak T, Kukull W, Borson S, Logsdon R, Cochrane B, Herting J. Multidimensional Complexity in the Dementias: Diagnosis, Stage, Comorbidity, and Neuropsychiatric Symptoms. Neurology, 78(S), Published 2012. (Abstract)

687.   Sayed N, Culver C, Hammond R, Diaz-Arrastia R. Clinical and Pathologic Phenotype of Dementia after Traumatic Brain Injury. National Neurotrauma Society, Accepted 2012. (Abstract)

688.   Sayegh P, Knight BG. Assessing the Cross-Cultural Measurement Properties of the Neuropsychiatric Inventory Questionnaire. Gerontological Society of America 65th Annual Scientific Meeting, San Diego, CA, Accepted 2012. (Abstract)

689.   Sayegh P, Knight BG. The Functional Assessment Questionnaire: Measurement Properties in Hispanics and Non-Hispanic Whites. Gerontological Society of America 65th Annual Scientific Meeting, San Diego, CA, Accepted 2012. (Abstract)

690.   Spackman DE, Kadiyala S, Neumann PJ, Veenstra DL, Sullivan SD. Measuring Alzheimer disease progression with transition probabilities: Estimates from NACC-UDS. Curr Alzheimer Res, 9:1050-1058, Published 2012, PMC3690579.

691.   Spering CC, Hobson V, Lucas JA, Menon CV, Hall JR, O'Bryant SE. Diagnostic accuracy of the MMSE in detecting probable and possible Alzheimer's disease in ethnically diverse highly educated individuals: an analysis of the NACC database. J Gerontol, 67:890-896, Published 2012, PMC3403860.

692.   Spiegel R. Modeling the Course of AD: Contributions to Better Clinical Trials. J Nutr Health Aging, 811-812, Published 2012. (Abstract)

693.   Steenland K, Karnes C, Seals R, Carnevale C, Hermida A, Levey A. Late-life depression as a risk factor for mild cognitive impairment or Alzheimer's disease in 30 US Alzheimer's disease centers. J Alzheimers Dis, 31:265-275, Published 2012, PMC3729228.

694.   Sullivan C, Onyike C, Brandt J. The clinical features of neuropathology-confirmed Hippocampal Sclerosis Dementia. 41st mtg Intl Neuropsychological Society, Accepted 2012. (Abstract)

695.   Teng E, Tassniyom K, Lu PH. Reduced quality-of-life ratings in mild cognitive impairment: analyses of subject and informant responses. Am J Geriatr Psychiatry, 20:1016-1025, Published 2012, PMC3513348.

696.   Whitcomb DC, LaRusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Conwell D, Cote GA, Cotton PB, DiSario J, Farrer LA, Forsmark CE, Johnstone M, Gardner TB, Gelrud A, Greenhalf W, Haines JL, Hartman DJ, Hawes RA, Lawrence C, Lewis M, Mayerle J, Mayeux R, Melhem NM, Money ME, Muniraj T, Papachristou GI, Pericak-Vance MA, Romagnuolo J, Schellenberg GD, Sherman S, Simon P, Singh VP, Slivka A, Stolz D, Sutton R, Weiss FU, Wilcox CM, Zarnescu NO, Wisniewski SR, O'Connell MR, Kienholz ML, Roeder K, Barmada MM, Yadav D, Devlin B. Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet, 44:1349-1354, Published 2012, PMC3510344.

697.   Wingo TS, Lah JL, Levey AI, Cutler DJ. Autosomal Recessive Causes Likely in Early-Onset Alzheimer Disease. Arch Neurol, 69:59-64, Published 2012, PMC3332307.

698.   Zhou XH, Duan X. Quantile Regression-based Covariate-Specific ROC Curves. WFN Annual Regional North American Meeting, Accepted 2012. (Abstract)

699.   Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Allen M, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Kouri N, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, ADGC Collaborators, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N. Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants. PLoS Genet, 8:e1002707, Published 2012, PMC3369937.

 
         2011
700.   Abner EL, Kryscio JR, Schmitt FA, Frederick A, Santacruz KA, Jicha GA, Lin Y, Neltner JM, Smith CD, Charles D, Van Eldik LJ, Linda J, Nelson PT. "End-stage" neurofibrillary tangle pathology in preclinical Alzheimer's disease-fact or fiction. J Alzheimers Dis, 25:445-453, Published 2011, PMC3171001.

701.   Beach T, Monsell S, Phillips L, Kukull WA. Comparison of Clinical and Neuropathological Definitions of Alzheimer's Disease at National Institute on Aging Alzheimer's Disease Centers, 2005-2010. Alzheimers Dement, 7:S525, Published 2011. (Abstract)

702.   Bliwise DL, Mercaldo ND, Avidan AY, Boeve BF, Greer SA, Kukull WA. Sleep disturbance in dementia with lewy bodies and Alzheimer's disease: a multicenter analysis. Dement Geriatr Cogn Disord, 31:239-246, Published 2011, PMC3085031.

703.   Bloudek LM, Spackman DE, Veenstra DL, Sullivan SD. CDR State Transition Probabilities in Alzheimer's Disease with an without Cholinesterase Inhibitor Intervention in an Observational Cohort. J Alzheimers Dis, 24:599-607, Published 2011, PMC3593724.

704.   Brookmeyer R, Evans DA, Hebert L, Langa KM, Heeringa SG, Plassman BL, Kukull WA. National estimates of the prevalence of Alzheimer's disease in the United States. Alzheimers Dement, 7:61-73, Published 2011, PMC3052294.

705.   Carrasquillo M, Olivia B, Talisha H, Ma L, Bisceglio G, Zou F, Crook J, Pankratz V, Sando S, Aasly J, Barcikowska M, Wszolek Z, Dickson D, Graff-Radford N, Petersen R, Morgan K, Younkin S. Replication of LOAD GWAS Associations. Alzheimers Dement, 7:S179, Published 2011. (Abstract)

706.   Chen B, Zhou A. Doubly Robust Estimates for Binary Longitudinal Data Analysis with Missing Response and Missing Covariates. Biometrics, 67:830-842, Published 2011, PMC3652597.

707.   Chen B, Zhou XHA. Non-Homogeneous Markov Process Models with Informative Observation Times, with an Application to Alzheimer's Disease. Alzheimers Dement, 7:S366, Published 2011. (Abstract)

708.   Chen B, Zhou XH. Non-homogeneous Markov process models with informative observations with an application to Alzheimer's disease. Biom J, 53:444-463, Published 2011, PMC3631600.

709.   Demichele-Sweet MA, Lopez OL, Sweet RA. Psychosis in Alzheimer's disease in the national Alzheimer's disease coordinating center uniform data set: clinical correlates and association with apolipoprotein e. Int J Alzheimers Dis, 2011:926597, Published 2011, PMC3065057.

710.   Frankel A. Patterns of Cognitive Decline by Dementia Subtype. Doctoral Dissertation, Alliant International University, Los Angeles, Defended 2011.

711.   Gill DP, Koepsell TD, Hubbard RA, Kukull WA. Risk of decline in functional activities in dementia with lewy bodies and Alzheimer disease. Alzheimer Dis Assoc Disord, 25:17-23, Published 2011, PMC3053143.

712.   Hanfelt JJ, Wuu J, Sollinger AB, Greenway MC, Lah J, Levey AI, Goldstein FC. An Exploration of Subgroups of Mild Cognitive Impairment Based On Cognitive, Neuropsychiatric and Functional Features: Analysis of Data from the National Alzheimer's Coordinating Center. Am J Geriatr Psychiatry, 19:940-950, Published 2011, PMC3202691.

713.   Hermida A, Seals R, Levey A, Steenland K. Cognitive Decline and Depression in 29 US Alzheimer Disease Centers. Alzheimers Dement, 7:S349-351, Published 2011. (Abstract)

714.   Hubbard RA, Zhou XH. A comparison of non-homogeneous Markov regression models with application to Alzheimer's disease progression. J Appl Stat, 38:2313-2326, Published 2011, PMC3299197.

715.   Johnson DK, Watts A, Chapin BA, Anderson R, Burns JM. Neuropsychiatric Profiles in Dementia. Alzheimer Dis Assoc Disord, 25:326-332, Published 2011, PMC3218373.

716.   Jun G, Buros J, Narayan Vardarajan B, Lunetta K, Farrer LA, ADGC Collaborators. Genome-wide scan suggested novel Alzheimer disease susceptibility genes by factoring influence of APOE. Alzheimers Dement, 7:S186, Published 2011. (Abstract)

717.   Kaur B, Harvey D, DeCarli C, Sabbagh M, Olichney J. Measurable Parkinsonism in Clinically Diagnosed Alzheimer's Disease: Associated with Mixed Neuropathologies. Neurology, 76:A622, Published 2011. (Abstract)

718.   Khachaturian ZS, Petersen RC, Snyder PJ, Khachaturian AS, Aisen P, de Leon M, Greenberg BD, Kukull W, Maruff P, Sperling RA, Stern Y, Touchon J, Vellas B, Andrieu S, Weiner MW, Carrillo MC, Bain LJ. Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010. Alzheimers Dement, 7:127-132, Published 2011.

719.   Knopman D, Weintraub S, Pankratz VS. Language and Behavior Domains Enhance the Value of the Clinical Dementia Rating Scale. Alzheimers Dement, 7:293-299, Published 2011, PMC3096831.

720.   Koepsell T, Monsell S. Characterizing Individuals who Revert from Mild Cognitive Impairment to Normal or Near-Normal Cognition. Alzheimers Dement, 7:S532, Published 2011. (Abstract)

721.   Koepsell T, Monsell S. Testing the First-Order Markov Assumption in Homogeneous Markov Modeling of Transition Probabilities between Cognitive States. Alzheimers Dement, 7:S351-352, Published 2011. (Abstract)

722.   Kukic V, Nan B, Wang X, Heidebrink J, Barbas N, Giordani B. Type 2 diabetes, but not hypercholesterolemia, is related to decrements in cognitive functioning among patients with MCI. Alzheimers Dement, 76:S270, Published 2011. (Abstract)

723.   Lau DT, Mercaldo ND, Shega JW, Rademaker A, Weintraub S. Functional decline associated with polypharmacy and potentially inappropriate medications in community-dwelling older adults with dementia. Am J Alzheimers Dis Other Demen, 26:606-615, Published 2011, PMC3298080.

724.   Liu D, Zhou A. A Model for Adjusting for Nonignorable Verification Bias in Estimation of ROC Curve and Its Area with Likelihood-Based Approach. Biometrics, 66:1119-1128, Published 2011, PMC3618959.

725.   Liu D, Zhou A. Semiparametric estimation of the covariate-specific ROC curve in presence of ignorable verification bias. Biometrics, 67:906-16, Published 2011, PMC3618959.

726.   Lu P, Saver JL, Beigi M, Vinters H, Ringman JM. Cognitive Predictors of Severe Cerebral Amyloid Angiopathy in Alzheimer's Disease Patients. Neurology, 76:A231, Published 2011. (Abstract)

727.   Martin ER, ADGC Collaborators. Genome-wide Association Analyses Identifies Novel Loci Associated with the Onset Age Among Cases with Late-Onset Alzheimer's Disease. Alzheimers Dement, 7:S188, Published 2011. (Abstract)

728.   Middleton LE, Grinberg LT, Miller B, Kawas C, Yaffe K. Neuropathologic features associated with Alzheimer disease diagnosis: age matters. Neurology, 77:1737-1744, Published 2011, PMC3208952.

729.   Monsell S, Liu D, Cosentino S, Weintraub S, Kukull WA. Comparing Global Measures of Cognitive Decline in Amnestic MCI Subjects in the National Alzheimer's Coordinating Center (NACC) Uniform Data Set. Alzheimers Dement, 7:S536, Published 2011. (Abstract)

730.   Naj AC, Jun G, ADGC Collaborators. Genome-wide Association Study of Late-Onset Alzheimer Disease Identifies Disease-Associated Variants in MS4A4/MS4A6E, CD2AP, CD33, and EPHA1. Alzheimers Dement, 7:S189-190, Published 2011. (Abstract)

731.   Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, George-Hyslop PS, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, Decarli C, Dekosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet, 43:436-441, Published 2011, PMC3090745.

732.   Nelson PT, Head E, Schmitt FA, Jicha GA, Abner E, Smith CD, Van Eldik LJ, Kryscio RJ, Scheff SW. Alzheimer's disease is not ”brain aging“: neuropathological, genetic, and epidemiological human studies. Acta Neuropathol, 121:571-587, Published 2011, PMC3179861.

733.   Nelson PT, Schmitt FA, Lin Y, Abner EL, Jicha GA, Patel E, Thomason PC, Neltner JH, Smith CD, Santacruz KS, Sonnen JA, Poon LW, Gearing M, Green RC, Woodard JL, Van Eldik LJ, Kryscio RJ. Hippocampal sclerosis in advanced age: clinical and pathological features. Brain, 134:1506-1518, Published 2011, PMC3097889.

734.   Phillips LE, Roe C, Monsell SE. Age, Education and Cognitive Impairment in an Autopsy Series of Subjects with Tau-positive Neuropathological Frontotemporal Lobar Degeneration in the National Alzheimer's Coordinating Center (NACC) Da. Alzheimers Dement, 7:S757, Published 2011. (Abstract)

735.   Ringman JM, Saver JL, Beigi M, Lu P, Vinters H. Clinical Predictors of Severe Cerebral Amyloid Angiopathy in Alzheimer's Disease Patients. Neurology, 76:A662, Published 2011. (Abstract)

736.   Rosenberg PB, Mielke MM, Appleby B, Oh E, Leoutsakos JM, Lyketsos CG. Neuropsychiatric symptoms in MCI subtypes: the importance of executive dysfunction. Int J Geriatr Psychiatry, 26:364-372, Published 2011, PMC3204866.

737.   Sadak T, Borson S, Cochrane BB, Kukull W, Logsdon R, Herting JR. Dementia Diagnoses, Neuropsychiatric Symptoms and Physical Comorbidities. Western Institute of Nursing Research, Accepted 2011. (Abstract)

738.   Sayed N, Diaz-Arrastia R. Clinical and Pathologic Phenotype of Dementia after Traumatic Brain Injury (TBI). Alzheimers Dement, 7:S750, Published 2011. (Abstract)

739.   Sayegh P, Knight BG. Differences in Predictors of a Dementia Diagnosis among Hispanic and nonHispanic White Outpatients. Gerontological Society of America (GSA) Meeting November, Accepted 2011. (Abstract)

740.   Shim YS, Morris JC, Buckles VD. Clinicopathologic Study of Alzheimer's Disease: Alzheimer Mimic. World Congress of Neurology, Accepted 2011. (Abstract)

741.   Shirk SD, Mitchell MB, Shaughnessy LW, Sherman JC, Locascio JJ, Weintraub S, Atri A. A web-based normative calculator for the uniform data set (UDS) neuropsychological test battery. Alzheimers Res Ther, 3:32, Published 2011, PMC3308021.

742.   Spiegel R, Berres M, Miserez AR, Monsch AU. The Placebo Group Simulation Approach (PGSA): An Alternative Study Design for Clinical Trials in Patients with Prodromal AD. CTAD Conference, San Diego November 3-5, Accepted 2011. (Abstract)

743.   Spiegel R. It really works! Confirmation of the ADNI-based Placebo Group Simulation Approach with NACC data. Alzheimers Dement, 7:e64, Published 2011. (Abstract)

744.   Stratton JH. Diagnostic Accuracy of a Binary Test in the Presence of Two Types of Missing Values. Doctoral Dissertation, University of Connecticut, Defended 2011.

745.   Thornton-Wells TA, Torstenson ES, Dudek SM, Ritchie MD, Martin E, Pericak-Vance MA, Haines JL, ADGC Collaborators. Discovery and replication of gene-gene interactions in multiple independent datasets from the Alzheimer Disease Genetics Consortium. Alzheimers Dement, 7:S195-196, Published 2011. (Abstract)

746.   Vardarajan B, Jun G, Buros J, Lunetta K, Farrer LA, ADGC Collaborators. Identification of gene-gene interactions for Alzheimer disease using co-operative game theory. Alzheimers Dement, 7:S196, Published 2011. (Abstract)

747.   Wang LS, Lin CF, Schellenberg G,ADGC Collaborators. Distribution of copy number variations in Alzheimer's Disease. Alzheimers Dement, 7:S271, Published 2011. (Abstract)

748.   Wang LS, Valladares O, Lin CF, Buros J, Naj A, Farrer L, Pericak-Vance M, Schellenberg G, ADGC Collaborators. The ADGC Genome Browser. Alzheimers Dement, 7:S271, Published 2011. (Abstract)

749.   Yamout K, Mungas D, Reed BR. Cardiovascular, Cerebrovascular, and Alzheimer's Disease and Cognition in an Autopsy Sample. Neurology, 76:A74, Published 2011. (Abstract)

 
         2010
750.   Beekly D, Koepsell T, Phillips L, Jacka M, Hubbard J, Wu J, Morris J, Phelps C, Kukull, WA. The NACC Uniform Data Set. Alzheimers Dement, 6:S457, Published 2010. (Abstract)

751.   Bloudek L, Spackman E, Sullivan SD. A Comparison of Transitions between Health States and Institutionalization among AD Patients vs Non-AD Dementia Patients Using the NACC-UDS Database. Value Health, 13:A108-A109, Published 2010. (Abstract)

752.   Chen B, Zhou A. Marginal Method for Multi-level Incomplete Binary Data. Joint Statistical Meeting 2010, Accepted 2010. (Abstract)

753.   Cummings J, Lee C. Neuropathologic correlates of trial-related clinical assessments. Alzheimers Dement, 6:S142, Published 2010. (Abstract)

754.   De Santi, S, Pirraglia, E, Ferris, SH, Morris, JC, Weintraub, S and Johnson, N. Robust norms for the ADC UDS cognitive test battery. Alzheimers Dement, 6:S495-S496, Published 2010. (Abstract)

755.   Ebner LL, Appleby B. Neuropsychiatric Manifestations in Dementia: Difference Between Young Onset and Lat Onset Presentation. Alzheimers Dement, 6:S341, Published 2010. (Abstract)

756.   Farrer LA, ADGC Collaborators. US Alzheimer Disease Genetics Consortium: Organization and Results. Alzheimers Dement, 6:S67, Published 2010. (Abstract)

757.   Ganguli M, Kukull WA. Lost in translation: epidemiology, risk, and Alzheimer disease. Arch Neurol, 67:107-111, Published 2010, PMC2806646.

758.   Gill D, Koepsell T, Hubbard RA, Kukull, WA. Risk of 1-year Decline in Functional Activities in Dementia with Lewy Bodies and Alzheimer's Disease. Neurology, 74:A431, Published 2010. (Abstract)

759.   Hernandez S, McClendon MJ, Zhou XH, Sachs M, Lerner AJ. Pharmacological treatment of Alzheimer's disease: effect of race and demographic variables. J Alzheimers Dis, 19:665-672, Published 2010, PMC2827609.

760.   Jun G, Naj AC, Beecham GW, Wang LS, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, Fallin MD, Friedland R, Inzelberg R, Kramer P, Rogaeva E, St George-Hyslop P, Cantwell LB, Dombroski BA, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Lunetta KL, Martin ER, Montine TJ, Goate AM, Blacker D, Tsuang DW, Beekly D, Cupples LA, Hakonarson H, Kukull W, Foroud TM, Haines J, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD. Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol, 67:1473-1484, Published 2010, PMC3048805.

761.   Kaur B, Harvey D, DeCarli C, Sabbagh M, Olichney J. Comparison of extrapyramidal signs (EPS) to dementia severity in Alzheimer's disease (AD) and Dementia with Lewy Bodies (DLB). Alzheimers Dement, 6:P2-174, Published 2010. (Abstract)

762.   Kielb SA, Okonkwo OC, Sur S, Kortte KB, Onyike CU. Education, Executive Functions and the Trajectory of Disability in Frontotemporal Dementia. Int'l Conference for Frontotemporal Dementia, Accepted 2010. (Abstract)

763.   Knopman D, Weintraub S, Pankratz VS. Language and Behavior Domain Enhance the Value of the Clinical Dementia Rating Scale. Neurology, 74:A429-A430, Published 2010. (Abstract)

764.   Koepsell T, Gill D, Chen B. Stability of Dementia Diagnosis in the National Alzheimer's Coordinating Center (NACC) Uniform Data Set. Alzheimers Dement, 6:S365, Published 2010. (Abstract)

765.   Lau DT, Mercaldo ND, Harris AT, Trittschuh E, Shega J and Weintraub S. Polypharmacy and potentially inappropriate medication use among community-dwelling elders with dementia. Alzheimer Dis Assoc Disord, 24:56-63, Published 2010, PMC2837122.

766.   Li G, Shofer JB, Rhew IC, Kukull WA, Peskind ER, McCormick W, Bowen JD, Schellenberg GD, Crane PK, Breitner JC, Larson EB. Age-varying association between statin use and incident Alzheimer's disease. J Am Geriatr Soc, 58:1311-1317, Published 2010, PMC3176730.

767.   Middleton LE, Grinberg L, Kawas CH, Miller B, Yaffe K. The Nueropathological Features Associated with Alzheimer's Disease Diagnosis in The Oldest Old Versus the Young Old. Alzheimers Dement, 6:S108-S109, Published 2010. (Abstract)

768.   Nelson PT, Jicha GA, Kryscio RJ, Abner EL, Schmitt FA, Cooper G, Xu LO, Smith CD, Markesbery WR. Low sensitivity in clinical diagnoses of dementia with Lewy bodies. J Neurol, 257:359-366, Published 2010, PMC2839040.

769.   Nelson PT, Kukull WA, Frosch MP. Thinking outside the box: Alzheimer-type neuropathology that does not map directly onto current consensus recommendations. J Neuropathol Exp Neurol, 69:449-454, Published 2010, PMC2892786.

770.   Nelson PT, Schmitt FA, Jicha GA, Kryscio RJ, Abner EL, Smith CD, Van Eldik LJ, Markesbery WR. Association between male gender and cortical Lewy body pathology in large autopsy series. J Neurol, 257:1875-1881, Published 2010, PMC3040648.

771.   O'Bryant SE, Lacritz LH, Hall J, Waring SC, Chan W, Khodr ZG, Massman PJ, Hobson V, Cullum CM. Validation of the new interpretive guidelines for the clinical dementia rating scale sum of boxes score in the national Alzheimer's coordinating center database. Arch Neurol, 67:746-749, Published 2010, PMC2888493.

772.   Petersen RC, Gill DP, Phillips LE, Aisen P. Early MCI as an Imaging Target: data from the National Alzheimer's Coordinating Center. Alzheimers Dement, 6:S58, Published 2010. (Abstract)

773.   Phillips L, Roe CM, Gill D, Koepsell TD, Morris JC. Family History, Demographics, and Genetic Characteristics of Symptomatic and Non-Symptomatic Subjects with Neuropathological Alzheimer's Disease in the National Alzheimer's Coordinating Center (NACC). Alzheimers Dement, 6:S126, Published 2010. (Abstract)

774.   Rosenberg PB, Lyketsos CG. A New Concept: The Concept of Mild Behavioral Impairment (MBI). Emotions Et Cognition Dans Les Maladies Neurologiques, Marseille France, Accepted 2010. (Abstract)

775.   Sachs M. Factors Associated with Brain Autopsy in a Large Sample of Decedents. Alzheimers Dement, 6:S460-S461, Published 2010. (Abstract)

776.   Sayed N, Diaz-Arrastia R. Clinical Phenotype of Dementia after Traumatic Brain Injury (TBI). Neurology, 74:A139, Published 2010. (Abstract)

777.   Steenland K, Macneil J, Bartell S, Lah J. Analyses of diagnostic patterns at 30 Alzheimer's disease centers in the US. Neuroepidemiology, 35:19-27, Published 2010, PMC2919431.

778.   Tartaglia MC, Mehta KM, Hu B, Miller BL, Boxer AL. Medication Use Differs in Alzheimer's disease and Frontotemporal dementia. Alzheimers Dement, 6:S589-S590, Published 2010. (Abstract)

779.   Teng E, Becker BW, Woo E, Cummings JL, Lu PH. Subtle Deficits in Instrumental Activities of Daily Living in Subtypes of Mild Cognitive Impairment. Dement Geriatr Cogn Disord, 30:189-197, Published 2010, PMC2948658.

780.   Teng E, Becker BW, Woo E, Knopman DS, Cummings JL, Lu PH. Utility of the Functional Activities Questionnaire for Distinguishing Mild Cognitive Impairment From Very Mild Alzheimer Disease. Alzheimer Dis Assoc Disord, 24:348-353, Published 2010, PMC2997338.

781.   Walters GD. Dementia: Continuum or distinct entity?. Psychol Aging, 25:534-544, Published 2010, PMC2943994.

782.   Yamout K. AD Pathology, Vascular Neuropathology and Cognition. Intl Neuropsychology Society Meeting, Accepted 2010. (Abstract)

 
         2009
783.   Acevedo A, Krueger KR, Navarro E, Ortiz F, Manly JJ, Padilla-Velez MM, Weintraub S, Lopez OL, Mungas D. The Spanish translation and adaptation of the Uniform Data Set of the National Institute on Aging Alzheimer's Disease Centers. Alzheimer Dis Assoc Disord, 23:102-109, Published 2009, PMC2963171.

784.   Gill DP, Koepsell TD, Kukull WA. Risk of Decline in Functional Activities in Dementia with Lewy Bodies and Alzheimer's Disease. Neuroepidemiology, 33:71, Published 2009. (Abstract)

785.   Hsieh HN, Su HY, Zhou XH. Interval estimation for the difference in paired areas under the ROC curves in the absence of a gold standard test. Stat Med, 28:3108-3123, Published 2009, PMC2812057.

786.   Kukull WA, Phillips L, Gill D, Wu J, Sachs M, Beekly D, Koepsell T. Primary Neuropathologic Diagnosis and Co-Occurrence of Other Neuropathologic Features: Results from the National Alzheimer's Coordinating Center (NACC). Alzheimers Dement, 5:P71-P72, Published 2009. (Abstract)

787.   Kukull WA. Commentary on a roadmap for the prevention of dementia II: Leon Thal Symposium 2008 "Big Asks": what can be changed to increase and speed progress on Alzheimer's disease research and treatment?". Alzheimers Dement, 5:137-139, Published 2009, PMC3744190.

788.   Lau DT, Mercaldo ND, Rademakers R, Shega J, Weintraub S. Cognitive, functional, and behavioral decline associated with polypharmacy and potentially inappropriate medication use in community-dwelling elders with and without dementia. American Public Health Association, 137th Annual Conference Philadelphia, PA, Accepted 2009. (Abstract)

789.   Longstreth WT, Sonnen JA, Koepsell TD, Kukull WA, Larson EB and Montine TJ. Associations between microinfarcts and other macroscopic vascular findings on neuropathologic examination in 2 databases. Alzheimer Dis Assoc Disord, 23:291-294, Published 2009, PMC2919361.

790.   McClendon MJ, Hernandez S, Smyth KA, Lerner AJ. Memantine and acetylcholinesterase inhibitor treatment in cases of CDR 05 or questionable impairment. J Alzheimers Dis, 16:577-583, Published 2009, PMC2827605.

791.   Nelson PT, Abner EL, Schmitt FA, Kryscio RJ, Jicha GA, Santacruz K, Smith CD, Patel E, Markesbery WR. Brains With Medial Temporal Lobe Neurofibrillary Tangles But No Neuritic Amyloid Plaques Are a Diagnostic Dilemma But May Have Pathogenetic Aspects Distinct From Alzheimer Disease. J Neuropathol Exp Neurol, 68:774-784, Published 2009, PMC2725359.

792.   Nelson PT, Kryscio RJ, Jicha GA, Abner EL, Schmitt FA, Xu LO, Cooper G, Smith CD, Markesbery WR. Relative preservation of MMSE scores in autopsy-proven dementia with Lewy bodies. Neurology, 73:1127-1133, Published 2009, PMC2764396.

793.   Phillips LE, Koepsell TD and Kukull WA. Refusal and Passive Loss-to-Follow-up in the NIA Alzheimer's Disease Program Uniform Data Set. Neurology, 72:A479-A480, Published 2009. (Abstract)

794.   Spackman DE. Measuring Progression in Alzheimer's Disease: 'Dependence' as a Health Outcome and Transition Probabilities Between Stages of Disease, Institutionalization and Death. Doctoral Dissertation, University of Washington, R01 AG027224, Defended 2009.

795.   Webster JA, Gibbs JR, Clarke J, Ray M, Zhang W, Holmans P, Rohrer K, Zhao A, Marlowe L, Kaleem M, McCorquodale DS, 3rd, Cuello C, Leung D, Bryden L, Nath P, Zismann VL, Joshipura K, Huentelman MJ, Hu-Lince D, Coon KD, Craig DW, Pearson JV, Heward CB, Reiman EM, Stephan D, Hardy J, Myers AJ. Genetic control of human brain transcript expression in Alzheimer disease. Am J Hum Genet, 84:445-458, Published 2009, PMC2667989.

796.   Weintraub S, Salmon D, Mercaldo N, Ferris S, Graff-Radford NR, Chui H, Cummings J, DeCarli C, Foster NL, Galasko D, Peskind E, Dietrich W, Beekly DL, Kukull WA, Morris JC. The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychologic test battery. Alzheimer Dis Assoc Disord, 23:91-101, Published 2009, PMC2743984.

 
         2008
797.   Becker B, Lu P, Woo E, Kim M, Cummings J. Insight into memory and mood functioning in amnestic mild cognitive impairment. 133rd Annual Meeting of the American Neurological Association, Salt Lake City, UT, Accepted 2008. (Abstract)

798.   Chi YY, Zhou XH. Receiver operating characteristic surfaces in the presence of verification bias. J Appl Stat, 57:1-23, Published 2008.

799.   Hong MG, Myers AJ, Magnusson PK, Prince JA. Transcriptome-wide assessment of human brain and lymphocyte senescence. PLoS One, 3:e3024, Published 2008, PMC2515343.

800.   Hubbard R, Zhou XH. A non-homogeneous Markov process model for Alzheimer's disease progression. Int Biometrics Society, 159, Published 2008. (Abstract)

801.   Hubbard RA, Zhou A. Modeling Risk Factors for Alzheimer's Disease Progression Using a Nonhomogeneous Markov Process. Joint Statistical Meeting, 193, Published 2008. (Abstract)

802.   Hubbard R. Identifying risk factors for conversion between normal cognition, MCI, and dementia using Markov processes. Alzheimers Dement, 4:T675-676, Published 2008. (Abstract)

803.   Ishihara-Paul L, Viswanathan A, Allen J, Hyman B, Betensky R, Weil J, Blacker D, Irizarry M. P30 use of an US claims database and an US Alzheimer's Disease registry to assess clinical trial eligibility criteria. Health and Aging, 12:543, Published 2008. (Abstract)

804.   Koepsell TD, Kurland BF, Harel O, Johnson EA, Zhou XH, Kukull WA. Education, cognitive function, and severity of neuropathology in Alzheimer disease. Neurology, 70:1732-1739, Published 2008.

805.   Maddox RA, Mercaldo ND, Deitrich WD, Holman RC, Gambetti P, Harvey AR, Schonberger LB, Kukull WA Belay ED. Clinically unrecognized cases of prion disease in the National Alzheimer's Coordinating Center Database. Prion 2008 conference Madrid Spain, Accepted 2008. (Abstract)

806.   Mercaldo N, Harris AT, Weintraub S, Lau DT. Potentially Inappropriate Medication Use Among Community-Dwelling Elderly Patients With Dementia In US Alzheimer's Disease Centers. 136th Annual Conference, Gerontological Health Section, Accepted 2008. (Abstract)

807.   Sachs M, Koepsell TD. Factors Associated with Brain Autopsy in a Large Multi-Center Sample of Decedents: A Multivariate Analysis. Alzheimers Dement, 4:T712, Published 2008. (Abstract)

808.   Steenland K, Macneil J, Lah J. Analyses of diagnostic patterns at 30 Alzheimer Disease Research Centers in the US. 10th Int'l Symposium on Neurobehavioral Methods and Effects in Environmental and Occupational Health (NEUREOH), San Jose, Costa Rica, Accepted 2008. (Abstract)

809.   Teng E, Becker B, Woo E, Knopman D, Cummings H, Mendez M, Lu P. Utility of the functional activities questionnaire for distinguishing mild cognitive impairment from mild Alzheimer's disease. J Int Neuropsychol Soc, 14:259, Published 2008. (Abstract)

810.   Teng E, Becker B, Woo E, Yau A, Cummings J, Mendez M, Lu P. Instrumental activities of daily living in subtypes of mild cognitive impairment. J Int Neuropsychol Soc, 13:259-260, Published 2008. (Abstract)

811.   Webster JA, Myers AJ, Pearson JV, Craig DW, Hu-Lince D, Coon KD, Zismann VL, Beach T, Leung D, Bryden L, Halperin RF, Marlowe L, Kaleem M, Huentelman MJ, Joshipura K, Walker D, Heward CB, Ravid R, Rogers J, Papassotiropoulos A, Hardy J, Reiman EM, Stephan DA. Sorl1 as an Alzheimer's disease predisposition gene?. Neurodegener Dis, 5:60-64, Published 2008.

812.   Weintraub S, Mercaldo N, Harris A, Lau D. Polypharmacy among Community-Dwelling Elderly Patients with Dementia: Analysis of the National Alzheimer's Coordinating Center Uniform Data Set. Alzheimers Dement, 4:T454, Published 2008. (Abstract)

 
         2007
813.   Beekly DL, Ramos EM, Lee WW, Deitrich WD, Jacka ME, Wu J, Hubbard JL, Koepsell TD, Morris JC, Kukull WA. The National Alzheimer's Coordinating Center (NACC) database: the Uniform Data Set. Alzheimer Dis Assoc Disord, 21:249-258, Published 2007.

814.   Deitrich W, Beekly D, Lee W, Koepsell T, Kukull W. Web-based Data Quality Assurance Reports at the National Alzheimer's Coordinating Center (NACC). Proceedings of the SAS® Global Forum 2007 Conference; 2007; Cary, NC: SAS Institute Inc, Accepted 2007. (Abstract)

815.   Harel O, Zhou XH. Multiple imputation for the comparison of two screening tests in two-phase Alzheimer studies. Stat Med, 26:2370-2388, Published 2007.

816.   Harel O, Zhou XH. Multiple imputation: review of theory, implementation and software. Stat Med, 26:3057-3077, Published 2007.

817.   Koepsell TD, Chi YY, Zhou XH, Lee WW, Ramos EM, Kukull WA. An alternative method for estimating efficacy of the AN1792 vaccine for Alzheimer disease. Neurology, 69:1868-1872, Published 2007.

818.   Koepsell TD, Chi YY, Zhou XH, Lee WW, Ramos EM, Kukull W. An alternative method for estimating efficacy of the AN1792 vaccine for Alzheimer's disease. Neurology, 68:A169-A170, Published 2007. (Abstract)

819.   Myers AJ, Gibbs JR, Webster JA, Rohrer K, Zhao A, Marlowe L, Kaleem M, Leung D, Bryden L, Nath P, Zismann VL, Joshipura K, Huentelman MJ, Hu-Lince D, Coon KD, Craig DW, Pearson JV, Holmans P, Heward CB, Reiman EM, Stephan D, Hardy J. A survey of genetic human cortical gene expression. Nat Genet, 39:1494-1499, Published 2007.

820.   Weiner MF, Hynan LS, Beekly D, Koepsell TD, Kukull WA. Comparison of Alzheimer's Disease in American Indians, Whites, and African Americans. Alzheimers Dement, 3:211-216, Published 2007.

 
         2006
821.   Beekly DL, Ramos EM, Jacka ME, Deitrich WD, Hubbard JD, Wu J, Lee WW, Morris JC, Kukull WA. The National Alzheimer's Coordinating Center's Data Submissions System and Database. Alzheimers Dement, 2:S267, Published 2006. (Abstract)

822.   Crane PK, Gibbons LE, Jolley L, van Belle G. Differential item functioning analysis with ordinal logistic regression techniques. DIFdetect and difwithpar. Med Care, 44:S115-123, Published 2006.

823.   Harel O, Zhou XH. Multiple imputation for correcting verification bias. Stat Med, 25:3769-3786, Published 2006.

824.   Kukull WA, Dickson DW, Montine TJ, Ramos EM, Zhang A, Koepsell TD. Lewy body (LB) pathology and clinical diagnoses in the National Alzheimer's Coordinating Center (NACC) database. Alzheimers Dement, 2:S430-431, Published 2006. (Abstract)

825.   Kukull WA. The growing global burden of dementia. Lancet Neurol, 5:199-200, Published 2006.

826.   Lee WW, Beekly DL, Ramos EM, Jacka ME, Deitrich WD, Hubbard JL, Wu J, Morris JS and Kukull WA. Using the web to collect data for Alzheimer's research. 11th World Congress on Internet & Medicine, Accepted 2006. (Abstract)

827.   Morris JC, Weintraub S, Chui HC, Cummings J, Decarli C, Ferris S, Foster NL, Galasko D, Graff-Radford N, Peskind ER, Beekly D, Ramos EM, Kukull WA. The Uniform Data Set (UDS): clinical and cognitive variables and descriptive data from Alzheimer Disease Centers. Alzheimer Dis Assoc Disord, 20:210-216, Published 2006.

828.   Morris JC. Uniform Data Set (UDS). Alzheimers Dement, 2:S261-S262, Published 2006. (Abstract)

829.   Noda A, Kraemer HC, Taylor JL, Schneider B, Ashford JW, Yesavage JA. Strategies to reduce site differences in multisite studies: a case study of Alzheimer disease progression. Am J Geriatr Psychiatry, 14:931-938, Published 2006.

830.   Zhang Z, Ramos E, Zhou A, Koepsell T, Kukull WA. Agreement between neuropathologic criteria for the diagnosis of Alzheimer's disease. Neurology, 66:283, Published 2006. (Abstract)

 
         2005
831.   Chow TW, Hodges JR, Dawson KE, Miller BL, Smith V, Mendez MF, Lipton AM. Referral patterns for syndromes associated with frontotemporal lobar degeneration. Alzheimer Dis Assoc Disord, 19:17-19, Published 2005, PMC1578638.

832.   Harel O, Koepsell T, Kukull WA, Zhou XH. Correcting for verification bias in the assessment of the accuracy of the clinical diagnosis of AD. Neurology, 64:A69, Published 2005. (Abstract)

833.   Honig LS, Kukull W, Mayeux R. Atherosclerosis and AD: analysis of data from the US National Alzheimer's Coordinating Center. Neurology, 64:494-500, Published 2005.

834.   Koepsell T, Kurland BF, Zhou XH, Harel O, Kukull WA. Education, cognitive function, and severity of neuropathology in Alzheimer's disease. 7th Intl Conference AD/PD Book of Abstracts, 67, Published 2005. (Abstract)

835.   Kurland BF, Kukull WA, Koepsell TD, Zhou XH, Ramos EP, Harel O. Impact of time scale choice on rate of cognitive decline: a case study from the National Alzheimer's Coordinating Center Minimum Data Set. Alzheimers Dement, 1:S33-34, Published 2005. (Abstract)

836.   Kurland BF, Heagerty PJ. Directly parameterized regression conditioning on being alive: analysis of longitudinal data truncated by deaths. Biostatistics, 6:241-258, Published 2005.

837.   Li G, Shofer JB, Kukull WA, Peskind ER, Tsuang DW, Breitner JC, McCormick W, Bowen JD, Teri L, Schellenberg GD, and Larson EB. Serum cholesterol and risk of Alzheimer disease: a community-based cohort study. Neurology, 65:1045-1050, Published 2005.

838.   Ramos EM, Koepsell TD, Kurland BF, Harel O, Zhou XH, Kukull WA. Pathology of subjects clinically diagnosed with vascular dementia. Vas Cog 2005 Abstract Book, 22, Published 2005. (Abstract)

 
         2004
839.   Beekly DL, Ramos EM, van Belle G, Deitrich W, Clark AD, Jacka ME, Kukull WA. The National Alzheimer's Coordinating Center (NACC) Database: an Alzheimer disease database. Alzheimer Dis Assoc Disord, 18:270-277, Published 2004.

840.   Crane PK, van Belle G, Larson EB. Test bias in a cognitive test: differential item functioning in the CASI. Stat Med, 23:241-256, Published 2004.

841.   Fitzpatrick AL, Kukull WA, Koepsell T, Higdon R. Survival by Type of Dementia: Data from the National Alzheimer's Coordinating Center. Neurology, 62:A452, Published 2004. (Abstract)

842.   Fitzpatrick AL, Kukull WA, Koepsell TD, Higdon R, Pfeiffer E, Kurland B. Depression within dementia subtypes: data from the National Alzheimer's Coordinating Center. Neurobiol, 25:479, Published 2004. (Abstract)

843.   Higdon R, Foster NL, Koeppe RA, DeCarli CS, Jagust WJ, Clark CM, Barbas NR, Arnold SE, Turner RS, Heidebrink JL, Minoshima S. A comparison of classification methods for differentiating fronto-temporal dementia from Alzheimer's disease using FDG-PET imaging. Stat Med, 23:315-326, Published 2004.

844.   Koepsell TD, Kukull WA, Beekly D, van Belle G, Higdon R, Fitzpatrick A, Kurland B. Public-use data from NACC. Neurobiol Aging, 25:386, Published 2004. (Abstract)

845.   Kukull WA. Perspectives on shared genetic contributions for Parkinson disease and Alzheimer disease. Arch Neurol, 61:1007-1008, Published 2004.

846.   Kurland BF, Heagerty PJ. Marginalized transition models for longitudinal binary data with ignorable and non-ignorable drop-out. Stat Med, 23:2673-2695, Published 2004.

847.   Li G, Higdon R, Kukull WA, Peskind E, Van Valen Moore K, Tsuang D, van Belle G, McCormick W, Bowen JD, Teri L, Schellenberg GD, Larson EB. Statin therapy and risk of dementia in the elderly: a community-based prospective cohort study. Neurology, 63:1624-1628, Published 2004.

848.   Pfeiffer EM, Higdon R, Koepsell TD, Fitzpatrick AL, Beekly DL, Kukull WA. Examining the agreement between CERAD and NIA/Regan Institute neuropathological criteria for the diagnosis of Alzheimer's disease. Neurobiol Aging, 25:134, Published 2004. (Abstract)

 
         2003
849.   Higdon R, Beekly D, Pfeiffer EA, van Belle G, Kukull WA. Sensitivity and specificity of Alzheimer's disease and dementia diagnoses for patients enrolled in NIA funded Alzheimer's Disease Centers. Neurology, 60:A309-A310, Published 2003. (Abstract)

850.   Kurland BF, Heagerty PJ. Targets of inference for longitudinal data censored by dropout and death. In: 2003 Proceedings of the American Statistical Association, Biometrics Section CD-ROM, Accepted 2003. (Abstract)

 
         2002
851.   Kukull WA, Higdon R, Bowen JD, McCormick WC, Teri L, Schellenberg GD, van Belle G, Jolley L, Larson EB. Dementia and Alzheimer disease incidence: a prospective cohort study. Arch Neurol, 59:1737-1746, Published 2002.

852.   Kukull WA, Bowen JD. Dementia epidemiology. Med Clin North Am, 86:573-590, Published 2002.

 
         2001
853.   Kukull WA. The association between smoking and Alzheimer's disease: effects of study design and bias. Biol Psychiatry, 49:194-199, Published 2001.

 
         2000
854.   Kukull WA, Ganguli M. Epidemiology of dementia: concepts and overview. Neurol Clin, 18:923-950, Published 2000.

 
       Externally-Funded Awards
         2017
855.   Hanfelt JJ. Latent Class Methods to Explore the Heterogeneity of Neurodegenerative Diseases. NIH, R01 AG055634, Funded 03/15/2017.

856.   Leow A, Thompson PM, Zhan L. Highly-sensitive imaging markers for early detection of Alzheimer's Disease using multi-view connectomics. NIH, 1R21AG056782-01, Funded 07/05/2017.

857.   Weintraub S, Gershon R. ARMADA: ADVANCING RELIABLE MEASUREMENT IN ALZHEIMER'S DISEASE AND COGNITIVE AGING. NIA, U2CAG057441, Funded 09/15/2017.

 
         2016
858.   Betensky R. Statistical methods for censored and dependently truncated data. National Institute of Health (NIH), 1R01NS094610-01A1, Funded 07/01/2016.

 
         2015
859.   Curry TE. Building Interdisciplinary Research Careers in Women's Health. NIH/NIDA, 5K12DA035150, Funded 01/01/2015.

860.   Farrer L. Alzheimer Disease Genetic Architecture in African Americans. National Institute of Health (NIH), R01 AG048927, Funded 02/15/2015.

861.   Jutkowitz E. Economic Model of Dementia: Projecting Costs and the Value of Non-pharmacologic Therapy to Guide Policy Making. Agency for Healthcare Research and Quality, 1R36HS024165-01, Funded 09/01/2015.

862.   Wingo T. Emory ADRC Project 2 - A Proteogenomic Approach to Understanding AD GWAS Results. NIH, AG025688, Funded 05/01/2015.

863.   Wingo T. Identifying New Genetic Targets in Alzheimer Disease. Lutrell Foundation, Funded 05/01/2015.

 
         2014
864.   Crane P. Genetic architecture of memory and executive functioning in Alzheimer's disease. NIH, R01 AG042437, Funded 09/01/2014.

865.   Fischer C. Neuroimaging correlates of delusions in Alzheimer's Disease and related dementias. CIHR, CSE313912, Funded 02/02/2014.

866.   Mattos M. Mild Cognitive Impairment in Older Rural Dwelling Adults. National Institute of Health (NIH), F31 NR015188, Funded 09/01/2014.

867.   Mez J. Genetic and Neuropsychological Heterogeneity in Alzheimer's Disease. National Institute of Health (NIH), K23 AG046377, Funded 08/15/2014.

 
         2013
868.   Nelson P. Sexually Dimorphic Mir-497 Regulates Alpha-Synuclein And Alpha-Synucleinopathy. NIH/NINDS, R21 NS085830, Funded 09/25/2013.

 
         2012
869.   Zhang J. Large Scale Biomarker Discovery and Validation for Parkinson's Disease. NIH/NINDS, U01 NS082137, Funded 09/30/2012.

 
         2011
870.   Gill DP. Predicting the Rate of Functional Decline in Alzheimer's Disease, Vascular Dementia, and Dementia with Lewy Bodies. CIHR, LAF-95193, Funded 01/04/2011.

871.   Kukull W, Koepsell T, Gill DP. Functional Decline in Three Demenia Types. NIH/NIA, R03 AG035027, Funded 09/01/2011.

872.   Kukull W, Morris J. LP Survey. Alzheimer Association, LPS-11-219245, Funded 09/01/2011.

 

NACC-Funded Junior Investigator Awards for Secondary Data Analyses: (TOTAL of 58)

   Principal Investigator: Miyeon Jung, PhD (NACC Project #2017-JI-04)
   Title: Testing a model of cognitive function with APOE and BDNF genes and heart failure
   Lead Institutions: Indiana University
 
       Publications
1.   Jung MJ, Apostolova LG, Gao S, Burney H, Lai D, Saykin AJ, Pressler SJ. Heart failure predicts cognitive dysfunction after adjusting for APOE factors. AAIC 2018, Accepted 2018. (Abstract)


   Principal Investigator: Shoshana Bardach, PhD (NACC Project #2017-JI-06)
   Title: Barriers to engagement in genetic research
   Lead Institutions: University of Kentucky
 
       Publications
2.   Bardach SH, Zhang X, Abner EL, Jicha GA. Provision of Genetic Samples within Alzheimer's Disease Centers: Factors associated with Sample Availability. AAIC 2018, Accepted 2018. (Abstract)


   Principal Investigator: Rahul Desikan, MD, PhD (NACC Project #2016-JI-01)
   Title: Predicting and quantifying Alzheimer's disease risk
   Lead Institutions: University of California, San Francisco
 
       Publications
3.   Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen C, Brewer JB, Karow DS, Kauppi K, Witoelar A, Karch CM, Bonham LW, Yokoyama JS, Rosen HJ, Miller BL, Dillon WP, Wilson DM, Hess CP, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Hardy J, Goate AM, Hyman BT, Schellenberg GD, McEvoy LK, Andreassen OA, Dale AM. Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. PLoS Med, 14:e1002258, Published 2017, PMC5360219.

4.   Tan CH, Hyman BT, Tan JJX, Hess CP, Dillon WP, Schellenberg GD, Besser LM, Kukull WA, Kauppi K, McEvoy LK, Andreassen OA, Dale AM, Fan CC, Desikan RS. Polygenic hazard scores in preclinical Alzheimer disease. Ann Neurol, 82:484-488, Published 2017, PMC5758043.


   Principal Investigator: Aaron Koenig, MD (NACC Project #2016-JI-02)
   Title: Lipophilic vs. hydrophilic statin exposure and post-mortem neuropathology
   Lead Institutions: Massachusetts ADRC
 
       Publications
5.   Koenig AM, Qian J, Betensky RA, Arnold SE. Lipophilic Versus Hydrophilic Statin Exposure and Post-Mortem Neuropathological Findings in the NACC Autopsy Cohort. Clinical Trials in Alzheimer's Disease (CTAD) Meeting, Accepted 2018. (Abstract)

6.   Koenig AM, Qian J, Betensky RA, Arnold SE. Lipophilic Versus Hydrophilic Statin Exposure and Post-Mortem Neuropathological Findings in the NACC Autopsy Cohort. MADRC/BU Thirtieth Annual Scientific Poster Symposium, Accepted 2017. (Abstract)


   Principal Investigator: Mitsuru Shinohara, PhD (NACC Project #2016-JI-08)
   Title: Effects of APOE genotype on longevity
   Lead Institutions: Mayo Clinic
 
       Publications
7.   Shinohara M, Kanekiyo T, Yang L, Linthicum D, Shinohara M, Fu Y, Price L, Penuliar MS, Wang M, Han X, Fryer J, Bu G. APOE2 eases cognitive decline during aging: clinical and preclinical evaluations. Ann Neurol, In press 2016, PMC5010530.


   Principal Investigator: Jonathan Graff-Radford, MD (NACC Project #2015-JI-01)
   Title: Predictors of survival in Lewy body disease
   Lead Institutions: Mayo Clinic
 
       Publications
8.   Graff-Radford J, Aakre J, Savica R, Boeve B, Kremers WK, Ferman TJ, Jones D, Kantarci K, Knopman DS, Dickson DW, Kukull WA, Petersen RC. Duration and Pathologic Correlates of Lewy Body Disease. JAMA Neurol, 74:310-315, Published 2017, PMC5527552.

9.   Graff-Radford J. Pathologic predictors of disease duration in Lewy body disease. Alzheimers Dement, 12:P698, Published 2016. (Abstract)


   Principal Investigator: Zheyu Wang, PhD (NACC Project #2015-JI-05)
   Title: Prognostic ability of MRI biomarkers for AD early detection and monitoring
   Lead Institutions: Johns Hopkins University
 
       Publications
10.   Wang Z, Sebestyen K, Monsell S. Model-based clustering for assessing the prognostic value of imaging biomarkers and mixed type tests. Comp Stat Data Anal, 113:123-135, Published 2017, PMC5613685.


   Principal Investigator: Yorghos Tripodis, PhD (NACC Project #2013-JI-02)
   Title: Predicting the Cognitive Status of an Aging Population
   Lead Institutions: Boston University
 
       Publications
11.   Tripodis Y, Zirogiannis N. Predicting the cognitive status of an aging population. Alzheimers Dement, 10:P722, Published 2014. (Abstract)

12.   Tripodis Y, Zirogiannisz N. Dynamic Factor Analysis for Multivariate Time Series: An application to cognitive trajectories. Int J Clin Biostat Biom, 1, Published 2015, PMC4704801.


   Principal Investigator: Brittany Dugger, PhD (NACC Project #2013-JI-03)
   Title: Relationship of Cardiovascular Risk Factors to Dementia Subtypes
   Lead Institutions: Arizona ADC
 
       Publications
13.   Dugger BN, Hentz JG, Adler CH, Sabbagh MN, Shill HA, Jacobson S, Caviness JN, Belden C, Driver-Dunckley E, Davis KJ, Sue LI, Beach TG, Consortium atAPD. Neuropathological Outcome of Prospectively Followed Normal Elderly Brain Bank Volunteers. Alzheimers Dement, 9:P336, Published 2013. (Abstract)

14.   Dugger BN, Hentz JG, Adler CH, Sabbagh MN, Shill HA, Jacobson S, Caviness JN, Belden C, Driver-Dunckley E, Davis KJ, Sue LI, Beach TG. Clinicopathological outcomes of prospectively followed normal elderly brain bank volunteers. J Neuropathol Exp Neurol, 73:244-252, Published 2014, PMC4066814.

15.   Dugger BN, Malek-Ahmadi M, Monsell S, Kukull W, Woodruff B, Reiman E, Beach TG, Wilson J. Cardiovascular Risk Factors and Their Interactions Among Clinically Defined Neurodegenerative Diseases. Alzheimers Dement, 10:P151-152, Published 2014. (Abstract)

16.   Dugger BN, Malek-Ahmadi M, Monsell SE, Kukull WA, Woodruff BK, Reiman EM, Beach TG, Wilson J. A Cross-Sectional Analysis of Late-Life Cardiovascular Factors and Their Relation to Clinically Defined Neurodegenerative Diseases. Alzheimer Dis Assoc Disord, 30:223-229, Published 2016, PMC4940303.

 
       Externally-Funded Awards
17.   Dugger B. Tau in peripheral tissues of PSP and CBD. CurePSP foundation, 531-15, Funded 10/31/2014.

18.   Dugger B. The effects of APOE genotype on APP and A-beta levels in human liver and brain. Arizona Department of Health Services (ADHS), Arizona Biomedical Research Commission (ABRC), ADHS14-082999, Funded 10/23/2014.

19.   Dugger B. The presence of tau in peripheral tissues across Alzheimer's disease stages. Alzheimer's association, AARG-16-441221, Funded 12/01/2017.


   Principal Investigator: Maritza Dowling MS, PhD (NACC Project #2012-JI-04)
   Title: Missing Data and the Identification of Optimal Predictors of Conversion to AD
   Lead Institutions: University of Wisconsin
 
       Publications
20.   Dowling NM. Missing Data and the Identification of Optimal Predictors of Conversion to AD. Alzheimers Dement, 9:P776-777, Published 2013. (Abstract)


   Principal Investigator: Joshua Grill (NACC Project #2012-JI-09)
   Title: Assessing Disease Progression Among Alzheimer's Disease Patients With Adult Child Study Partners
   Lead Institutions: University of California, Los Angeles
 
       Publications
21.   Grill JD, Zhou Y, Karlawish J, Elashoff D. Does study partner type impact the rate of Alzheimer's disease progression. J Nutr Health Aging, 17:816, Published 2013. (Abstract)

22.   Grill JD, Zhou Y, Karlawish J, Elashoff D. Does study partner type impact the rate of Alzheimer's disease progression?. J Alzheimers Dis, 38:507-514, Published 2014, PMC3842422.

23.   Grill JD, Zhou Y, Karlawish J, Elashoff D. Frequency and Impact of Informant Replacement in Alzheimer Disease Research. Alzheimer Dis Assoc Disord, 29:242-248, Published 2015, PMC4486637.

24.   Grill JD, Zhou Y, Karlawish J, Elashoff D. The impact of study partner change in Alzheimer's disease research. Alzheimers Dement, 10:P852, Published 2014. (Abstract)


   Principal Investigator: Heather Romero (NACC Project #2011-JI-06)
   Title: Diagnostic Stability of Transitional States in a Diverse Population
   Lead Institutions: Duke University
 
       Publications
25.   Romero H, Zhao S, Perez M, Bougard C, Montero J, Smith R, Welsh-Bohmer KA, Plassman BL, Hayden K. Cognitive and Functional Predictors of Incident Alzheimer's Disease: Data from the National Alzheimer's Coordinating Center (NACC). Alzheimers Dement, 13:P884, Published 2017. (Abstract)

 
       Externally-Funded Awards
26.   Romero H. Big Questions in Cognitive Aging: An Integrative Analysis Approach. NIH, 1R03AG045494-01, Funded 08/15/2013.


   Principal Investigator: Katherine Gifford PhD (NACC Project #2011-JI-08)
   Title: Subjective Memory Complaint and Cognitive Aging
   Lead Institutions: Boston University
 
       Publications
27.   Gifford KA, Carmona H, Tripodis Y, Martin B, Cantwell N, Kowall N, Jefferson AL. Subjective Cognitive Complaint Predicts Cognitive and Functional Trajectory in Individuals with Mild Cognitive Impairment. Int'l Neuropsychological Society Meeting, Accepted 2012. (Abstract)

28.   Gifford KA, Liu D, Lu Z, Carmona H, Romano R, Tripodis Y, Martin B, Kowall N, Jefferson AL. Inclusion of an informant yields strong associations between cognitive complaint and longitudinal cognitive outcomes in non-demented elders. J Alzheimers Dis, 43:121-132, Published 2015, PMC4314962.

29.   Gifford KA, Liu D, Lu Z, Tripodis Y, Cantwell N, Palmisano J, Kowall N, Jefferson AL. The source of cognitive complaints predicts diagnostic conversion differentially among nondemented older adults. Alzheimers Dement, 10:319-327, Published 2014, PMC4064681.

30.   Tripodis Y, Palmisano J, Gentile A, Jefferson A. Subjective Complaint and Cognitive Aging. Alzheimers Dement, 7:S545, Published 2011. (Abstract)


   Principal Investigator: Patrick Brown PhD (NACC Project #2010-JI-01)
   Title: Common Functional Deficits in MCI and Dementia
   Lead Institutions: Columbia University
 
       Publications
31.   Brown PJ, Liu X, Sneed JR, Pimontel MA, Devanand DP, Roose SP. Speed of processing and depression affect function in older adults with mild cognitive impairment. Am J Geriatr Psychiatry, 21:675-684, Published 2013, PMC3410965.

32.   Brown PJ, Sneed JR, Rutherford B, Devanand DP, Roose SP. The nuances of cognition and depression in older adults: the need for a comprehensive assessment. Int J Geriatr Psychiatry, 29:506-514, Published 2014, PMC3975802.

33.   Devanand DP, Liu X, Brown PJ. Impact of Functional Deficits in Instrumental Activities of Daily Living in Mild Cognitive Impairment: A Clinical Algorithm to Predict Progression to Dementia. Alzheimer Dis Assoc Disord, 1:55-61, Published 2017, PMC5321859.

 
       Externally-Funded Awards
34.   Brown P. Targeting Dopaminergic Mechanisms of Slowing to Improve Late Life Depression. NIMH, R61MH110029, Funded 04/01/2016.


   Principal Investigator: Berneet Kaur, MD (NACC Project #2010-JI-05)
   Title: The Influence of Smoking History on the Phenotype and Pathology of Dementia
   Lead Institutions: University of California, Davis
 
       Publications
35.   Kaur B, Harvey D, Tong E, Hofstetter CR, DeCarli C, Olichney J. A Comparison of Extrapyramidal Signs Between Smokers and Nonsmokers with Dementia. Neurology, 80:P07.153, Published 2013. (Abstract)

36.   Kaur B, Harvey D, Tong E, Hofstetter CR, DeCarli C, Olichney J. The relationship of smoking history and vascular risk factors to motor parkinsonism in dementia. Neurology, 78(1):P04202, Published 2012. (Abstract)


   Principal Investigator: Kathleen Hayden PhD (NACC Project #2008-JI-02)
   Title: Identification of Cognitive Endophenotypes
   Lead Institutions: Duke University
 
       Publications
37.   Hayden KM, Jones RN, Zimmer C, Plassman B, Browndyke JN, Pieper C, Warren LH, Welsh-Bohmer KA. Factor Structure of the National Alzheimer's Coordinating Centers Uniform Dataset Neuropsychological Battery: An evaluation of invariance between and within groups over time. Alzheimer Dis Assoc Disord, 25:128-137, Published 2011, PMC3101374.

38.   Hayden KM, Kuchibhatla M, Plassman BL, Romero HR, Burke JR, Welsh-Bohmer KA. Pre-clinical cognitive phenotypes for Alzheimer's disease: a latent profile approach. Alzheimers Dement, 8:P363, Published 2012. (Abstract)

39.   Hayden KM, Kuchibhatla M, Romero HR, Plassman BL, Burke JR, Browndyke JN, Welsh-Bohmer KA. Pre-clinical cognitive phenotypes for Alzheimer disease: a latent profile approach. Am J Geriatr Psychiatry, 22:1364-1374, Published 2014, PMC3968245.

40.   Hayden KM, Warren LH, Plassman B, Browndyke J, Pieper C, Sanders L, Welsh-Bohmer KA. Neuropsychological Domains in Mild Cognitive Impairment and Normal Aging: Results from the NACC UDS Study. Alzheimers Dement, 5:P448, Published 2009. (Abstract)


   Principal Investigator: Ann Mayo, RN DNSc (NACC Project #2007-JI-01)
   Title: Determinants of Judgment and Problem Solving Among Patients with Dementia
   Lead Institutions: UC, San Francisco
 
       Publications
41.   Mayo AM, Wallhagen M, Cooper BA, Mehta K, Ross L, Miller B. The relationship between functional status and judgment/problem solving among individuals with dementia. Int J Geriatr Psychiatry, 28:514-521, Published 2013, PMC3496819.

42.   Mayo, AM, Wallhagen, M, Cooper, BA, Mehta, K, Ross, L and Miller, B. Determinants of Judgment and Problem Solving in Persons with Dementia. American Geriatrics Society Annual Meeting in Chicago on April 30, 2009, Accepted 2009. (Abstract)


   Principal Investigator: Liana Apostolova, MD (NACC Project #2007-JI-02)
   Title: Behavioral Reserve in MCI and AD
   Lead Institutions: University of California, Los Angeles
 
       Publications
43.   Apostolova L, Tseng C, Fairbanks L, Elashoff D, Cummings J. Effect of age, gender, marital status and education on behavioral symptoms in MCI and mild AD subjects. Neurology, 74:A21, Published 2010. (Abstract)

44.   Apostolova LG, Di LJ, Duffy EL, Brook J, Elashoff D, Tseng CH, Fairbanks L, Cummings JL. Risk factors for behavioral abnormalities in mild cognitive impairment and mild Alzheimer's disease. Dement Geriatr Cogn Disord, 37:315-326, Published 2014, PMC4057985.

45.   Apostolova LG, Di LJ, Tseng CH, Fairbanks L, Elashoff D, Cummings JL. Behavioral reserve in mild cognitive impairment and mild Alzheimer's disease. Alzheimers Dement, 8:P323, Published 2012. (Abstract)

46.   Apostolova LG, Di LJ, Tseng CH, Fairbanks L, Elashoff D, Cummings JL. Comparison of the prevalence of neuropsychiatric behaviors between amnestic and nonamnestic MCI subjects. Alzheimers Dement, 8:P135, Published 2012. (Abstract)


   Principal Investigator: Catherine Roe (NACC Project #2005-JI-03)
   Title: Education, the cognitive reserve hypothesis, and Alzheimer’s Disease Without Dementia
   Lead Institutions: Washington University
 
       Publications
47.   Roe CM, Xiong C, Grant E, Miller JP, Morris JC. Education and reported onset of symptoms among individuals with Alzheimer disease. Arch Neurol, 65:108-111, Published 2008, PMC2830808.

48.   Roe CM, Xiong C, Miller JP, Cairns NJ, Morris JC. Interaction of neuritic plaques and education predicts dementia. Alzheimer Dis Assoc Disord, 22:188-193, Published 2008, PMC2770714.

49.   Roe CM, Xiong C, Miller JP, Morris JC. Diffuse and Neuritic Plaques, Neurofibrillary Tangles, and APOE Genotype in Preclinical AD. Alzheimers Dement, 2:S247, Published 2006. (Abstract)

50.   Roe CM, Xiong C, Miller JP, Morris JC. Education and Alzheimer disease without dementia: support for the cognitive reserve hypothesis. Neurology, 68:223-228, Published 2007.

51.   Roe CM, Xiong C, Miller P, Morris JC. Education and Preclinical Alzheimer's Disease without Dementia. Alzheimers Dement, 2:S146, Published 2006. (Abstract)

52.   Roe CM, Xiong CJ, Miller JP, Morris J. Education and Neuropathological Alzheimer s Disease, With and Without Dementia. Neurology, 66:A218, Published 2006. (Abstract)


   Principal Investigator: Michael Rapp A. (NACC Project #2005-JI-09)
   Title: Neuropathological Changes in Dementia in Patients with Co-morbid Depression
   Lead Institutions: Mount Sinai School of Medicine
 
       Publications
53.   Rapp MA, Haroutunina V, Sano M. Increased Plaques and Tangles in Alzheimer's Disease Patients with Co-morbid Depression. Society for Biological Psychiatry Annual Meeting, Toronto, Canada, Accepted 2006. (Abstract)

54.   Rapp MA, Schnaider-Beeri M, Purohit DP, Perl DP, Haroutunian V, Sano M. Increased neurofibrillary tangles in patients with Alzheimer disease with comorbid depression. Am J Geriatr Psychiatry, 16:168-174, Published 2008.


   Principal Investigator: Kala Mehta (NACC Project #2005-JI-11)
   Title: Ethnic Differences in Alzheimer’s Disease Survival and Pathology
   Lead Institutions: University of California, San Francisco
 
       Publications
55.   Mehta K, Kurland B, Barnes D, Yaffe K, Miller B, Perez-Stable EJ. African American and Latino AD Patients have longer survival than white AD patients: data from the National Alzheimer's Coordinating Center datasets. National Meeting of the Resource Center for Minority Aging Research, Accepted 2006. (Abstract)

56.   Mehta KM, Yaffe K, Perez-Stable EJ, Stewart A, Barnes D, Kurland BF, Miller BL. Race/ethnic differences in AD survival in US Alzheimer's Disease Centers. Neurology, 70:1163-1170, Published 2008, PMC2830859.

57.   Mehta KM, Kurland B, Barnes D, Yaffe K, Perez-Stable E, Miller B. African American and Latino Alzheimer's disease patient's have longer survival than white Alzheimer's disease patients: Data from the National Alzheimer's Coordinating Center datasets. Neurology, 66:A218, Published 2006. (Abstract)

58.   Ontaneda D, Mehta KM, Perez-Stable E. Race/ethnic differences in AD survival in us Alzheimer's disease centers. Neurology, 72:1620, Published 2009.


NACC Funded Collaborative Projects (by project): (TOTAL of 190)

   Principal Investigator: Thomas Montine, MD, PhD (NACC Project #2012-02)
   Title: Optimization of the Neuropathologic Assessment of Alzheimer's Disease
   Lead Institutions: University of Washington
 
       Publications
1.   Montine TJ, Monsell SE, Beach TG, Bigio EH, Bu Y, Cairns JA, Frosch M, Henriksen J, Kofler J, Kukull WA, Lee EB, Nelson PT, Schantz AM, Schneider JA, Sonnen JA, Trojanowski JQ, Vinters HV, Zhou XH, Hyman BT. Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease. Alzheimers Dement, 12:164-169, Published 2016, PMC4562409.


   Principal Investigator: Teresa Gomez-Isla MD, PhD (NACC Project #2011-03)
   Title: Are Some Human Brains Able to Resist Alzheimer's Pathology?
   Lead Institutions: Massachusetts ADRC
 
       Publications
2.   Barroeta-Espar I, Gómez Pérez-Nievas B, Meltzer A, Marquie M, García-Polite F, Moulder K, Morris JC, Parisi E, Petersen R, Ikonomovic M, López O, Vonsattel J, Mayeux R, Hyman BT, Gómez-Isla T. Accrual of oligomeric tau in synapses and glial reaction are more proximate correlates to cognition than plaques and tangles. Society for Neuroscience, Accepted 2014. (Abstract)

3.   Perez-Nievas BG, Stein TD, Tai HC, Dols-Icardo O, Scotton TC, Barroeta-Espar I, Fernandez-Carballo L, de Munain EL, Perez J, Marquie M, Serrano-Pozo A, Frosch MP, Lowe V, Parisi JE, Petersen RC, Ikonomovic MD, Lopez OL, Klunk W, Hyman BT, Gomez-Isla T. Dissecting phenotypic traits linked to human resilience to Alzheimer's pathology. Brain, 136:2510-2526, Published 2013, PMC3722351.

 
       Externally-Funded Awards
4.   Gomez-Isla MT. Dissecting molecular mechanisms involved in resilience to Alzheimer's pathology. NIH/NIA, R01 AG043511, Funded 09/01/2013.


   Principal Investigator: Linda Boise, PhD, MPH (NACC Project #2010-05)
   Title: Ethnic Differences in Willingness to Assent to Brain Donation
   Lead Institutions: Oregon Health  Science U
 
       Publications
5.   Boise L, Hinton L, Rosen H, Ruhl M. Will my soul go to heaven if they take my brain? Beliefs and worries about brain donation among four ethnic groups. Gerontologist, 57:719-734, Published 2017, PMC in process.

6.   Boise L, Hinton L, Rosen HJ, Ruhl M, Dodge H, Mattock N, Albert M, Denny A, Grill JD, Hughes T, Lingler J, Morhardt D, Parfitt F, Peterson-Hazank S, Pop V, Rose T, Shah RC. Willingness to Be a Brain Donor: A Survey of Research Volunteers From 4 Racial/Ethnic Groups. Alzheimer Dis Assoc Disord, 31:135-140, Published 2017, PMC5403614.


   Principal Investigator: Brent Small (NACC Project #2008-01)
   Title: Changes in Cognitive performance in Preclinical AD: A Collaborative Analysis
   Lead Institutions: Florida ADC
 
       Publications
7.   Small BJ, Dixon RA, McArdle JJ. Tracking Cognition-Health Changes From 55 to 95 Years of Age. J Gerontol, 66:i153-161, Published 2011, PMC3132770.


   Principal Investigator: John H. Growdon, MD (NACC Project #2007-01)
   Title: Lewy Body Diseases Imaged with PiB
   Lead Institutions: Massachusetts ADRC
 
       Publications
8.   Gomperts SN, Johnson KA, Growdon J. Reply: Beyond the limits of detection: failure of PiB imaging to capture true Abeta burden. Mov Disord, 28:407, Published 2013, PMC3741662.

9.   Gomperts SN, Locascio JJ, Marquie M, Santarlasci AL, Rentz DM, Maye J, Johnson KA, Growdon JH. Brain amyloid and cognition in Lewy body diseases. Mov Disord, 27:965-973, Published 2012, PMC3725259.

10.   Growdon J, Gomperts S, Locascio J, Rentz D, Marquie Sayagues M, Santarlasci A, Johnson K. Brain Amyloid and Cognition in PD. 10th Int'l Conference on Alzheimer's and Parkinson's Disease; Barcelona, Spain, Accepted 2011. (Abstract)


   Co-Principal Investigator: Anne Fagan Niven & Alex Roher (NACC Project #2006-03,06)
   Title: Proteomic Analysis of Post-mortem and Ante-mortem Cerebrospinal Fluid for the Diagnosis of Alzheimer’s Disease
   Lead Institutions: WashU/Arizona ADC
 
       Publications
11.   Craig-Schapiro R, Perrin RJ, Roe CM, Grant EA, Carter D, Cairns NJ, Mintun MA, Peskind ER, Li G, Galasko DR, Clark CM, Quinn JF, D'Angelo G, Malone JP, Townsend R, Morris JC, Fagan AM, Holtzman DM. A Novel Diagnostic and Prognostic Fluid Biomarker for Early Alzheimer's Disease: YKL-40. Alzheimers Dement, 6:S506, Published 2010. (Abstract)

12.   Craig-Schapiro R, Perrin RJ, Roe CM, Xiong C, Carter D, Cairns NJ, Mintun MA, Peskind ER, Li G, Galasko DR, Clark CM, Quinn JF, D'Angelo G, Malone JP, Townsend RR, Morris JC, Fagan AM, Holtzman DM. YKL-40: a novel prognostic fluid biomarker for preclinical Alzheimer's disease. Biol Psychiatry, 68:903-912, Published 2010, PMC3011944.

13.   Maarouf CL, Andacht TM, Kokjohn TA, Castano EM, Sue LI, Beach TG, Roher AE. Proteomic analysis of Alzheimer's disease cerebrospinal fluid from neuropathologically diagnosed subjects. Curr Alzheimer Res, 6:399-406, Published 2009, PMC2832860.

14.   Perrin RJ, Craig-Schapiro R, Malone JP, Roe CM, Grant EA, Shah AR, Gilmore P, Davis AE, Peskind ER, Li G, Galasko DR, Quinn JF, Kaye JA, Clark CM, Morris JC, Holtzman DM, Townsend RR, Fagan AM. Identification and validation of novel cerebrospinal fluid protein biomarkers for early Alzheimer disease using proteomics and ELISA - a multi-institutional collaborative study. Alzheimers Dement, 6:S500, Published 2010. (Abstract)

15.   Perrin RJ, Craig-Schapiro R, Malone JP, Shah AR, Gilmore P, Davis AE, Roe CM, Peskind ER, Li G, Galasko DR, Clark CM, Quinn JF, Kaye JA, Morris JC, Holtzman DM, Townsend RR, Fagan AM. Identification and Validation of Novel Cerebrospinal Fluid Biomarkers for Staging Early Alzheimer's Disease. PLoS One, 6:e16032, Published 2011, PMC3020224.

16.   Perrin RJ, Malone JP, Shah AR, Craig-Schapiro R, Gilmore P, Davis AE, Peskind ER, Ge L, Galasko DR, Quinn JF, Kaye JA, Clark CM, Morris JC, Holtzman DM, Townsend RR, Fagan AM. Identification of potential biomarkers for Alzheimer's disease in cerebrospinal fluid using two-dimensional difference gel electrophoresis (2D-DIGE) and tandem mass spectrometry-a multi-institutional. Alzheimers Dement, 4:T543, Published 2008. (Abstract)

17.   Roher AE, Maarouf CL, Andacht TM, Kokjohn TA, Castano EM, Walker DG, Sabbagh MN, Beach TG. Proteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimer's disease. Alzheimers Dement, 6:S123, Published 2010. (Abstract)

18.   Roher AE, Maarouf CL, Sue LI, Hu Y, Wilson J, Beach TG. Proteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimer's disease. Biomarkers, 14:493-501, Published 2009, PMC2824250.


   Principal Investigator: Mony J. deLeon (NACC Project #2006-09)
   Title: Hippocampal Glucose Metabolism in Aging: Relationships to Cognitive Decline
   Lead Institutions: New York University School of Medicine
 
       Publications
19.   Mosconi L, Tsui WH, Herholz K, Pupi A, Drzezga A, Lucignani G, Reiman EM, Holthoff V, Kalbe E, Sorbi S, Diehl-Schmid J, Perneczky R, Clerici F, Caselli R, Beuthien-Baumann B, Kurz A, Minoshima S, de Leon MJ. Multicenter standardized 18F-FDG PET diagnosis of mild cognitive impairment, Alzheimer's disease, and other dementias. J Nucl Med, 49:390-398, Published 2008, PMC3703818.


   Principal Investigator: Sandra Weintraub (NACC Project #2005-05)
   Title: Clinical Phenotypes of FTD are Determined by Neuropathologic and Biochemical Features
   Lead Institutions: Northwestern University
 
       Publications
20.   Armstrong RA, Cairns NJ. Analysis of beta-amyloid (Abeta) deposition in the temporal lobe in Alzheimer's disease using Fourier (spectral) analysis. Neuropathol Appl Neurobiol, 36:248-257, Published 2010, PMC2972722.

21.   Armstrong RA, Ellis W, Hamilton RL, Mackenzie IR, Hedreen J, Gearing M, Montine T, Vonsattel JP, Head E, Lieberman AP, Cairns NJ. Neuropathological heterogeneity in frontotemporal lobar degeneration with TDP-43 proteinopathy: a quantitative study of 94 cases using principal components analysis. J Neural Transm, 117:227-239, Published 2010, PMC2830004.

22.   Cairns NJ, Bigio EH, Mackenzie IR, Neumann M, Lee VM, Hatanpaa KJ, White CL, 3rd, Schneider JA, Grinberg LT, Halliday G, Duyckaerts C, Lowe JS, Holm IE, Tolnay M, Okamoto K, Yokoo H, Murayama S, Woulfe J, Munoz DG, Dickson DW, Ince PG, Trojanowski JQ, Mann DM. Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathol, 114:5-22, Published 2007, PMC2827877.

23.   Cairns NJ, Neumann M, Bigio EH, Holm IE, Troost D, Hatanpaa KJ, Foong C, White CL, 3rd, Schneider JA, Kretzschmar HA, Carter D, Taylor-Reinwald L, Paulsmeyer K, Strider J, Gitcho M, Goate AM, Morris JC, Mishra M, Kwong LK, Stieber A, Xu Y, Forman MS, Trojanowski JQ, Lee VM, Mackenzie IR. TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. Am J Pathol, 171:227-240, Published 2007, PMC1941578.

24.   Cairns NJ, Pang-Hsien T, Bigio EH, Schneider JA, White III CL, Hatanpaa K, Aggarwal NT, Womake KB, Schneider S, Grinberg LT, Morris JC, Wicklund AH, Weintraub S. Neuropathologic heterogeneity in frontotemporal lobar degeneration (FTLD) with ubiquitin inclusions: Report of the Midwest consortium for FTLD. Brain Pathol, 16:S5, Published 2006. (Abstract)

25.   Gitcho MA, Baloh RH, Chakraverty S, Mayo K, Norton JB, Levitch D, Hatanpaa KJ, White CL, 3rd, Bigio EH, Caselli R, Baker M, Al-Lozi MT, Morris JC, Pestronk A, Rademakers R, Goate AM, Cairns NJ. TDP-43 A315T mutation in familial motor neuron disease. Ann Neurol, 63:535-538, Published 2008, PMC2747362.

26.   Gitcho MA, Bigio EH, Mishra M, Johnson N, Weintraub S, Mesulam M, Rademakers R, Chakraverty S, Cruchaga C, Morris JC, Goate AM, Cairns NJ. TARDBP 3'-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy. Acta Neuropathol, 118:633-645, Published 2009, PMC2783457.

27.   Hatanpaa KJ, Bigio EH, Cairns NJ, Schneider JA, Foong C, Hladik C, Shang P, White CL. TDP-43 immunohistochemistry reveals extensive neuritic pathology in FTLD-U: a Midwest-Southwest Consortium for FTLD study. J Neuropathol Exp Neurol, 66:425, Published 2007. (Abstract)

28.   Hatanpaa KJ, Bigio EH, Cairns NJ, Womack KB, Weintraub S, Morris JC, Foong C, Xiao G, Hladik C, Mantanona TY, White III CL. TAR DNA-binding protein 43 immunohistochemistry reveals extensive neuritic pathology in FTLD-U: a midwest-southwest consortium for FTLD study. J Neuropathol Exp Neurol, 67:271-279, Published 2008, PMC2635119.

29.   Liscic RM, Grinberg LT, Zidar J, Gitcho MA, Cairns NJ. ALS and FTLD: two faces of TDP-43 proteinopathy. Eur J Neurol, 15:772-780, Published 2008, PMC2801606.


   Principal Investigator: Debby Tsuang, MD (NACC Project #2003-03)
   Title: Clinical, Pathologic, and Genetic Characteristics of Dementia with Lewy Bodies
   Lead Institutions: University of Washington
 
       Publications
30.   Bekris LM, Tsuang D, Leverenz JB, Yu CE, Lutz F, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA, Kramer P, Woltjer R, Trojanowski JQ, Weintraub D, Chen-Plotkin AS, Irwin DJ, Rick J, Schellenberg GD, Watson GS, Kukull W, Nelson PT, Jicha GA, Neltner JH, Galasko D, Masliah E, Quinn JF, Chung KA, Yearout D, Mata IF, Edwards KL, Montine TJ, Zabetian CP. A TOMM40 SNP in APOE ε4 Non-carriers Increases Risk for Multiple Types of Dementia. Alzheimers Dement, 9:P555, Published 2013. (Abstract)

31.   Chow SW, Peterson M, Vavrek DJ, Steinbart E, Bird TD, Leverenz JB, Tsuang DW. Diagnostic Accuracy of Concomitant Lewy-Related Pathology in a Kindred with Familial Alzheimer's Disease: a Clinical-Neuropathological Study. Summer Training on Aging Research Topics in Mental Health (START-MH), Accepted 2006. (Abstract)

32.   Ericksen S, Tsuang DW. Dementia with Lewy bodies. In: Fuji D, Ahmed I, eds Spectrum Psychotic Disorders: Neurobiology, Etiology & Pathogenesis New York: Cambridge University Press, 472-489, Published 2007.

33.   Leverenz JB, Fishel MA, Peskind ER, Montine TJ, Nochlin D, Steinbart E, Raskind MA, Schellenberg GD, Bird TD, Tsuang D. Lewy body pathology in familial Alzheimer disease - Evidence for disease- and mutation-specific pathologic phenotype. Arch Neurol, 63:370-376, Published 2006, PMC1892620.

34.   Leverenz JB, Hamilton R, Tsuang DW, Schantz A, Vavrek D, Larson EB, Kukull WA, Lopez O, Galasko D, Masliah E, Kaye J, Woltjer R, Clark C, Trojanowski JQ, Montine TJ. Empiric refinement of the pathologic assessment of Lewy-related pathology in the dementia patient. Brain Pathol, 18:220-224, Published 2008, PMC2689097.

35.   Leverenz JB, Hamilton RL, Tsuang DW, Schantz A, Vavrek D, Larson EB, Kukull WA, Lopez OL, Galasko D, Masliah E, Kaye J, Nixon R, Clark C, Trojanowski J, Montine TJ. Empirical refinement of pathologic assessment of Dementia with Lewy Bodies. Alzheimers Dement, Accepted 2006. (Abstract)

36.   Leverenz JB, Larson EB, Vavrek D, Peskind ER, Bowen JD, McCormick WC, Teri L, Kukull WA, Montine TJ and Tsuang DW. "Amygdala predominant" Lewy body disease: a subtype of Alzheimer's disease with a more aggressive clinical course. Alzheimers Dement, 2:S16, Published 2006. (Abstract)

37.   Lopez A, Samii A, Griffith A, Roberts J, Leis B, Mosley A, Yearout D, Schellenberg G, Bird T, Raskind W, Leverenz J, Tsuang D, Zabetian C. Comprehensive mutational analysis of LRRK2 in familial Parkinson's disease and dementia with Lewy bodies. Neurology, 66:277, Published 2006. (Abstract)

38.   Mata IF, Samii A, Schneer SH, Roberts JW, Griffith A, Leis BC, Schellenberg GD, Sidransky E, Bird TD, Leverenz JB, Tsuang D, Zabetian CP. Glucocerebrosidase gene mutations: a risk factor for lewy body disorders. Arch Neurol, 65:379-382, Published 2008, PMC2826203.

39.   Mata IF, Schneer SH, Samii A, Roberts JW, Griffith AF, Leis BC, Leverenz JB, Schellenberg GD, Sidransky E, Tsuang DW, Zabetian CP. Case-control analysis of glucocerebrosidase gene mutations in Parkinson's disease and dementia with Lewy bodies. Mov Disord, 22:S128-S129, Published 2007. (Abstract)

40.   Nakashima-Yasuda H, Uryu K, Robinson J, Xie SX, Hurtig H, Duda JE, Arnold SE, Siderowf A, Grossman M, Leverenz JB, Woltjer R, Lopez OL, Hamilton R, Tsuang DW, Galasko D, Masliah E, Kaye J, Clark CM, Montine TJ, Lee VM, Trojanowski JQ. Co-morbidity of TDP-43 proteinopathy in Lewy body related diseases. Acta Neuropathol, 114:221-229, Published 2007.

41.   Ohtake H, Limprasert P, Fan Y, Onodera O, Kakita A, Takahashi H, Bonner LT, Tsuang DW, Murray IV, Lee VM, Trojanowski JQ, Ishikawa A, Idezuka J, Murata M, Toda T, Bird TD, Leverenz JB, Tsuji S, La Spada AR. Beta-synuclein gene alterations in dementia with Lewy bodies. Neurology, 63:805-811, Published 2004, PMC1808539.

42.   Schneer S, Mata IF, Samii A, Roberts JW, Griffith A, Leis BC, Leverenz JB, Schellenberg GD, Sidransky E, Tsuang DW, Zabetian CP. Case-control Analysis of Glucocerebrosidase Gene Mutations in Parkinson's Disease and Dementia with Lewy Bodies. American Academy of Neurology, Accepted 2007. (Abstract)

43.   Tsuang D, Larson EB, Bolen E, Thompson ML, Peskind E, Bowen J, McCormick W, Teri L, Kukull W, Vavrek D, Montine T, Leverenz JB. Visual hallucinations in dementia: a prospective community-based study with autopsy. Am J Geriatr Psychiatry, 17:317-323, Published 2009, PMC2742470.

44.   Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA, Kramer P, Woltjer R, Kukull W, Nelson PT, Jicha GA, Neltner JH, Galasko D, Masliah E, Trojanowski JQ, Schellenberg GD, Yearout D, Huston H, Fritts-Penniman A, Mata IF, Wan JY, Edwards KL, Montine TJ, Zabetian CP. GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology. Neurology, 79:1944-1950, Published 2012, PMC3484986.

45.   Tsuang D, Simpson K, Larson EB, Peskind E, Kukull W, Bowen JB, McCormick W, Teri L, Montine T, Thompson ML, Leverenz JB. Predicting lewy body pathology in a community-based sample with clinical diagnosis of Alzheimer's disease. J Geriatr Psychiatry Neurol, 19:195-201, Published 2006.

46.   Tsuang DW, Hamilton RL, Lopez OL, Wilson R, Luedecking-Zimmer E, Kamboh L, DeKosky ST, Larson EB, Kukull WA, Schellenberg GD, Leverenz J. Age and concomitant LB pathology modify the genetic association between Alzheimer's disease and the APOE-e4 allele. 3rd International Workshop on Dementia with Lewy Bodies and Parkinson's Disease; Dementia Conference Handbook, 147, Published 2003. (Abstract)

47.   Tsuang DW, Larson EB, Peskind ER, Bowen JB, McCormick W, Teri L, Jennings-Vavrek D, Montine T, Thompson ML, Leverenz JB. Visual hallucinations and Lewy body pathology: a community-based autopsy case series. Alzheimers Dement, 2:S146, Published 2006. (Abstract)

48.   Tsuang DW, Purganan K, Steinbart E, Bird TD, Montine T and Leverenz JB. Concomitant Lewy body pathology a marker for more aggressive course in familial Alzheimer's disease. Neurology, 64:A361-A362, Published 2005. (Abstract)

49.   Tsuang DW, Riekse R, Bird TD, Muilenberg M, Steinbart E, McCutcheon M, Purganan K, Leverenz JB. Familial Dementia with Lewy Bodies. Neurobiol Aging, 25:86, Published 2004. (Abstract)

50.   Tsuang DW, Riekse RG, Purganan KM, David AC, Montine TJ, Schellenberg GD, Steinbart EJ, Petrie EC, Bird TD, Leverenz JB. Lewy body pathology in late-onset familial Alzheimer's disease: A clinicopathological case series. J Alzheimers Dis, 9:235-242, Published 2006.

51.   Tsuang DW, Wilson RK, Lopez OL, Luedecking-Zimmer EK, Leverenz JB, DeKosky ST, Kamboh MI, Hamilton RL. Genetic association between the APOE*4 allele and Lewy bodies in Alzheimer disease. Neurology, 64:509-513, Published 2005, PMC1487185.

52.   Zabetian CP, Lauricella CJ, Tsuang DW, Leverenz JB, Schellenberg GD, Payami H. Analysis of the LRRK2 G2019S mutation in Alzheimer Disease. Arch Neurol, 63:156-157, Published 2006.


   Principal Investigator: Roger Rosenberg, MD (NACC Project #2002-01)
   Title: Statin Effects on Platelet APP Ratios and AD Dementia
   Lead Institutions: University of Texas Southwestern
 
       Publications
53.   Baskin F, Rosenberg RN, Fang X, Hynan LS, Moore CB, Weiner M, Vega GL. Correlation of platelet amyloid precursor protein ratios and declining cognition in Alzheimer's disease: A new severity index. Neurobiol Aging, 23:S384, Published 2002. (Abstract)

54.   Baskin F, Rosenberg RN, Fang X, Hynan LS, Moore CB, Weiner M, Vega GL. Correlation of statin-increased platelet APP ratios and reduced blood lipids in AD patients. Neurology, 60:2006-2007, Published 2003.

55.   Diaz-Arrastia R, Baskin F. New biochemical markers in Alzheimer disease. Arch Neurol, 58:354-356, Published 2001.

56.   Qu B, Boyer PJ, Johnston SA, Hynan LS, Rosenberg RN. Abeta42 gene vaccination reduces brain amyloid plaque burden in transgenic mice. J Neurol Sci, 244:151-158, Published 2006, PMC1531642.

57.   Qu B, Rosenberg RN, Li L, Boyer PJ, Johnston SA. Gene vaccination to bias the immune response to amyloid-beta peptide as therapy for Alzheimer disease. Arch Neurol, 61:1859-1864, Published 2004.

58.   Qu BX, Xiang Q, Li L, Johnston SA, Hynan LS, Rosenberg RN. Abeta42 gene vaccine prevents Abeta42 deposition in brain of double transgenic mice. J Neurol Sci, 260:204-213, Published 2007, PMC2587214.

59.   Tang K, Hynan LS, Baskin F, Rosenberg RN. Platelet amyloid precursor protein processing: a bio-marker for Alzheimer's disease. J Neurol Sci, 240:53-58, Published 2006, PMC1479090.


   Principal Investigator: Harry Vinters (NACC Project #2002-03)
   Title: Tissue Reactions to CAA Study Using Tissue Microarrays (CNS Complications of Amyloid Angiopathy)
   Lead Institutions: University of California, Los Angeles
 
       Publications
60.   Farag ES, Miyata H, Vinters HV. CAA severity and reactive change in Alzheimer disease: A tissue microarray study. J Neuropathol Exper Neurol, 62:553, Published 2003. (Abstract)

61.   Green DA, Masliah E, Vinters HV, Beizai P, Moore DJ, Achim CL. Brain deposition of beta-amyloid is a common pathologic feature in HIV positive patients. J Int AIDS Soc, 19:407-411, Published 2005.

62.   Vinters HV, Klement IA, Sung SH, Farag ES. Pathologic issues and new methodologies in the evaluation of non-Alzheimer dementias. Clin Neurosci Res, 3:413-426, Published 2004.


   Principal Investigator: Robert Sweet, MD (NACC Project #2002-04)
   Title: Genetics of Alzheimer’s Disease With Psychosis
   Lead Institutions: University of Pittsburgh
 
       Publications
63.   Bacanu SA, Devlin B, Chowdari KV, DeKosky ST, Nimgaonkar VL, Sweet RA. Heritability of psychosis in Alzheimer disease. Am J Geriatr Psychiatry, 13:624-627, Published 2005.

64.   Cook SE, Miyahara S, Bacanu SA, Perez-Madrinan G, Lopez OL, Kaufer DI, Nimgaonkar VL, Wisniewski SR, DeKosky ST, Sweet RA. Psychotic symptoms in Alzheimer disease: evidence for subtypes. Am J Geriatr Psychiatry, 11:406-413, Published 2003.

65.   Eror EA, Emanuel JE, Miyahara S, Lopez OL, DeKosky ST, Sweet RA. Excess Cognitive Impairment Precedes The Emergence Of Psychosis In Alzheimer Disease. Alzheimers Dement, 2:S375-376, Published 2006. (Abstract)

66.   Eror EA, Lopez OL, DeKosky ST, Sweet RA. AD subjects with psychosis have increased subsyndromal psychotic symptoms prior to dementia onset. Neurobiol Aging, 25:S489, Published 2004. (Abstract)

67.   Eror EA, Lopez OL, Dekosky ST, Sweet RA. Alzheimer disease subjects with psychosis have increased schizotypal symptoms before dementia onset. Biol Psychiatry, 58:325-330, Published 2005.

68.   Go RC, Perry RT, Wiener H, Bassett SS, Blacker D, Devlin B, Sweet RA. Neuregulin-1 polymorphism in late onset Alzheimer's disease families with psychoses. Am J Med Genet B Neuropsychiatr Genet, 139:28-32, Published 2005.

69.   Go RC, Perry RT, Wiener H, Bassett SS, Blacker D, Devlin BJ, Sweet RA. Neuregulin-1 polymorphism in load with psychosis in the NIMH AD sibling families. Neurobiol Aging, 25:S488, Published 2004. (Abstract)

70.   Lopez OL, Becker JT, Saxton J, Sweet RA, Klunk W, DeKosky ST. Alteration of a clinically meaningful outcome in the natural history of Alzheimer's disease by cholinesterase inhibition. J Am Geriatr Soc, 53:83-87, Published 2005.

71.   Lopez OL, Becker JT, Sweet RA, Hamilton RL, DeKosky ST. Relationship between major depression and Lewy bodies in Alzheimer's disease. Neurology, 62:A159-A160, Published 2004. (Abstract)

72.   Lopez OL, Becker JT, Sweet RA, Klunk W, Kaufer DI, Saxton J, DeKosky ST. Patterns of change in the treatment of psychiatric symptoms in patients with probable Alzheimer's disease from 1983 to 2000. J Neuropsychiatry Clin Neurosci, 15:67-73, Published 2003.

73.   Lopez OL, Becker JT, Sweet RA, Klunk W, Kaufer DI, Saxton J, Habeych M, DeKosky ST. Psychiatric symptoms vary with the severity of dementia in probable Alzheimer's disease. J Neuropsychiatry Clin Neurosci, 15:346-353, Published 2003.

74.   Lopez OL, Becker JT, Sweet RA, Klunk W, Saxton J, DeKosky ST. Incident psychiatric symptoms predict conversion to dementia in mild cognitive impairment subgroups. Neurobiol Aging, 25:S32, Published 2004. (Abstract)

75.   Lopez OL, Becker JT, Sweet RA. Non-cognitive symptoms in mild cognitive impairment subjects. Neurocase, 11:65-71, Published 2005.

76.   Lopez OL, Becker JT, Sweet RS, Klunk W, Saxton J, DeKosky ST. Response letter to Dr Thomas Finucane. J Am Geriatr Soc, 53:1831-1833, Published 2005.

77.   Lopez OL, Miyahara S, Becker JT, Sweet RA, Klunk W, Saxton J, DeKosky ST. Incident psychiatric symptoms predict conversion to dementia in Mild Cognitive Impairment subgroups. In: Vellas B, ed Research and Practice in Alzheimer's Disease and Cognitive Decline: Paris, Serdi, 89-95, Published 2005.

78.   Lopez OL. Incident Psychiatric symptoms predict the development of Mild Cognitive Impairment subgroups. Ninth International Conference on Alzheimer Disease and Related Disorders, Accepted 2004. (Abstract)

79.   Perez-Madrinan G, Cook SE, Saxton JA, Miyahara S, Lopez OL, Kaufer DI, Aizenstein HJ, DeKosky ST, Sweet RA. Alzheimer disease with psychosis: excess cognitive impairment is restricted to the misidentification subtype. Am J Geriatr Psychiatry, 12:449-456, Published 2004.

80.   Perez-Madrinan G, Cook SE, Saxton JA, Miyahara S, Lopez OL, Kaufer DI, Aizenstein HJ, DeKosky ST, Sweet RA. Psychosis in Alzheimer Disease: Excess Cognitive Impairment is Restricted to the Misidentification Subtype. Advances in Geriatric Psychiatry Translating Research Into Care:101, Accepted 2003. (Abstract)

81.   Prasad KMR, Davis SW, Becker JT, Keshavan MS, Sweet RA. Neurobiological substrates of Alzheimer Disease with psychosis: an exploratory study of structural MRI using a voxel-based morphometric approach. Society for Neuroscience 33rd Annual Meeting, Accepted 2003. (Abstract)

82.   Sweet R, Emanuel J E. Psychosis Secondary to Alzheimer Disease. In: Ahmed DFaI, ed The Spectrum of Psychotic Disorders: Neurobiology, Etiology, and Pathogenesis Cambridge UK: Cambridge University Press, Published 2005.

83.   Sweet RA, Bacanu SA, Devlin B, Chowdari KV, DeKosky ST, Nimgaonkar VL. Heritability of psychosis in Alzheimer disease. Neurobiol Aging, 25:S54, Published 2004. (Abstract)

84.   Sweet RA, Devlin B, Pollock BG, Sukonick DL, Kastango KB, Bacanu SA, Chowdari KV, DeKosky ST, Ferrell RE. Catechol-o-methyltransferase haplotype is associated with psychosis in Alzheimer's disease. American Association for Geriatric Psychiatry 17th Annual Meeting, Baltimore MD, Accepted 2004. (Abstract)

85.   Sweet RA, Devlin B, Pollock BG, Sukonick DL, Kastango KB, Bacanu SA, Kodavali VC, DeKosky ST, Ferrell RE. Catechol-o-methyltransferase haplotype is associated with psychosis in Alzheimer's disease. Mol Psychiatry, 10:1026-1036, Published 2005.

86.   Sweet RA. Genetics of Alzheimer Disease with Psychosis. SOBP Annual Convention and Scientific Program San Francisco California, Accepted 2003. (Abstract)

87.   Sweet RA. Heritability of Psychosis in Alzheimer Disease. Ninth International Conference on Alzheimer Disease and Related Disorders, Accepted 2004. (Abstract)

88.   Sweet RA. Recent Advances in the Clinical Neuroscience of Alzheimer's Disease. American Association for Geriatric Psychiatry 17th Annual Meeting, Baltimore MD, Accepted 2004. (Abstract)

89.   Sweet RA. Spanning the GAP: Genes, Alzheimer Disease, and Psychosis. Grand Rounds Mt Sinai School of Medicine, Presented 2005. (Presentation)

90.   Sweet RA. Taking a New Look At Psychosis in Alzheimer's Disease. GRECC Weekly Conference Series, VA Hospital , Pittsburgh PA, Presented 2003. (Presentation)

91.   Sweet RA. The genetic basis of psychosis in Alzheimer Disease (and why it matters). Geriatric Research, Education and Clinical Center (CRECC) conference series, Presented 2006. (Presentation)

92.   Wilkosz PA, Miyahara S, Lopez O, Dekosky S, Sweet R. Psychotic symptoms identify subtypes of AD: A prospective validation study. Neurobiol Aging, 25:S495, Published 2004. (Abstract)

93.   Wilkosz PA, Miyahara S, Lopez OL, DeKosky ST, Eror EA, Sweet RA. HTR2A genotype, depression, and risk for psychosis onset in Alzheimer disease. Alzheimers Dement, 2:S183, Published 2006. (Abstract)

94.   Wilkosz PA, Miyahara S, Lopez OL, DeKosky ST, Sweet RA. HTR2A Genotype, Depression, And Risk For Psychosis Onset In Alzheimer Disease. Precedings of the International Congress on Geriatric Psychoneuropharmacology, Accepted 2005. (Abstract)

95.   Wilkosz PA, Miyahara S, Lopez OL, Dekosky ST, Sweet RA. Prediction of psychosis onset in Alzheimer disease: The role of cognitive impairment, depressive symptoms, and further evidence for psychosis subtypes. Am J Geriatr Psychiatry, 14:352-360, Published 2006.

 
       Externally-Funded Awards
96.   Bacanu SA. Method to detect genetic variants underlying psychiatric disease susceptibility. Young Investigator-NARSAD, Funded 07/01/2003.

97.   Chowdari KV. Genetic Analysis of AD with Psychosis. Alzheimer Association-NIRG, Funded 08/01/2003.

98.   Sweet RA. Prediction of Psychosis in Alzheimer's Disease. NIH/NIA, R01 AG027224, Funded 07/01/2006.


   Principal Investigator: John Morris, MD (NACC Project #2001-03)
   Title: Neuropathologic Correlates of Nondemented Aging
   Lead Institutions: Washington University
 
       Publications
99.   Burack MA, Hartlein J, Flores HP, Taylor-Reinwald L, Perlmutter JS, Cairns NJ. In vivo amyloid imaging in autopsy-confirmed Parkinson disease with dementia. Neurology, 74:77-84, Published 2010, PMC2809026.

100.   Morris J. Neuropathologic Correlates of Non-demented Aging. In Washington University, Published 2001.

101.   Morris JC, Price JL, McKeel DW, Higdon R, Buckles VD. The Neuropathology of Nondemented Aging. Neurobiol Aging, 25:137, Published 2004. (Abstract)

102.   Price JL, McKeel Jr DW, Buckles VD, Roe CM, Xiong C, Grundman M, Hansen LA, Petersen RC, Parisi JE, Dickson DW, Smith CD, Davis DG, Schmitt FA, Markesbery WR, Kaye J, Kurlan R, Hulette C, Kurland BF, Higdon R, Kukull W, Morris JC. Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease. Neurobiol Aging, 30:1026-1036, Published 2009, PMC2737680.


   Principal Investigator: Elaine Peskind, MD (NACC Project #2001-04)
   Title: CSF Cortisol and APOE Genotype
   Lead Institutions: University of Washington
 
       Publications
103.   Abdi F, Quinn JF, Jankovic J, McIntosh M, Leverenz JB, Peskind E, Nixon R, Nutt J, Chung K, Zabetian C, Samii A, Lin M, Hattan S, Pan C, Wang Y, Jin J, Zhu D, Li GJ, Liu Y, Waichunas D, Montine TJ, Zhang J. Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders. J Alzheimers Dis, 9:293-348, Published 2006.

104.   Friedman LF, Zeitzer JM, Lin L, Hoff D, Mignot E, Peskind ER, Yesavage JA. In Alzheimer disease, increased wake fragmentation found in those with lower hypocretin-1. Neurology, 68:793-794, Published 2007.

105.   Li G, Sokal I, Quinn JF, Leverenz JB, Brodey M, Schellenberg GD, Kaye JA, Raskind MA, Zhang J, Peskind ER, Montine TJ. CSF tau/Abeta42 ratio for increased risk of mild cognitive impairment: a follow-up study. Neurology, 69:631-639, Published 2007.

106.   Pan S, Wang Y, Quinn JF, Peskind ER, Waichunas D, Wimberger JT, Jin J, Li JG, Zhu D, Pan C, Zhang J. Identification of glycoproteins in human cerebrospinal fluid with a complementary proteomic approach. J Proteome Res, 5:2769-2779, Published 2006.

107.   Pan S, Zhu D, Quinn JF, Peskind ER, Montine TJ, Lin B, Goodlett DR, Taylor G, Eng J, Zhang J. A combined dataset of human cerebrospinal fluid proteins identified by multi-dimensional chromatography and tandem mass spectrometry. Proteomics, 7:469-473, Published 2007.

108.   Pasinetti GM, Ungar LH, Lange DJ, Yemul S, Deng H, Yuan X, Brown RH, Cudkowicz ME, Newhall K, Peskind E, Marcus S, Ho L. Identification of potential CSF biomarkers in ALS. Neurology, 66:1218-1222, Published 2006.

109.   Peskind ER, Griffin WS, Akama KT, Raskind MA, Van Eldik LJ. Cerebrospinal fluid S100B is elevated in the earlier stages of Alzheimer's disease. Neurochem Int, 39:409-413, Published 2001.

110.   Peskind ER, Li G, Shofer J, Quinn JF, Kaye JA, Clark CM, Farlow MR, DeCarli C, Raskind MA, Schellenberg GD, Lee VM, Galasko DR. Age and apolipoprotein E*4 allele effects on cerebrospinal fluid beta-amyloid 42 in adults with normal cognition. Arch Neurol, 63:936-939, Published 2006.

111.   Peskind ER, Wilkinson CW, Petrie EC, Schellenberg GD, Raskind MA. Increased CSF cortisol in AD is a function of APOE genotype. Neurology, 56:1094-1098, Published 2001.

112.   Riekse RG, Li G, Petrie EC, Leverenz JB, Vavrek D, Vuletic S, Albers JJ, Montine TJ, Lee VM, Lee M, Seubert P, Galasko D, Schellenberg GD, Hazzard WR, Peskind ER. Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid. J Alzheimers Dis, 10:399-406, Published 2006.

113.   Vuletic S, Peskind ER, Marcovina SM, Quinn JF, Cheung MC, Kennedy H, Kaye JA, Jin LW, Albers JJ. Reduced CSF PLTP activity in Alzheimer's disease and other neurologic diseases; PLTP induces ApoE secretion in primary human astrocytes in vitro. J Neurosci Res, 80:406-413, Published 2005.

114.   Vuletic S, Riekse RG, Marcovina SM, Peskind ER, Hazzard WR, Albers JJ. Statins of different brain penetrability differentially affect CSF PLTP activity. Dement Geriatr Cogn Disord, 22:392-398, Published 2006.

115.   Xu J, Chen J, Peskind ER, Jin J, Eng J, Pan C, Montine TJ, Goodlett DR, Zhang J. Characterization of proteome of human cerebrospinal fluid. Int Rev Neurobiol, 73:29-98, Published 2006.

116.   Zhang H, Loriaux P, Eng J, Campbell D, Keller A, Moss P, Bonneau R, Zhang N, Zhou Y, Wollscheid B, Cooke K, Yi EC, Lee H, Peskind ER, Zhang J, Smith RD, Aebersold R. UniPep--a database for human N-linked glycosites: a resource for biomarker discovery. Genome Biol, 7:R73, Published 2006, PMC1779586.

117.   Zhang J, Goodlett DR, Peskind ER, Quinn JF, Zhou Y, Wang Q, Pan C, Yi E, Eng J, Aebersold RH, Montine TJ. Quantitative proteomic analysis of age-related changes in human cerebrospinal fluid. Neurobiol Aging, 26:207-227, Published 2005.

118.   Zhang J, Goodlett DR, Quinn JF, Peskind E, Kaye JA, Zhou Y, Pan C, Yi E, Eng J, Wang Q, Aebersold RH, Montine TJ. Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease. J Alzheimers Dis, 7:125-133, Published 2005.

 
       Externally-Funded Awards
119.   Raskind M. Psychopathology of Alzheimer's: APOE and the HPA Axis. NIH/NIA, R01 AG008419, Funded 07/01/2001.

120.   Riekse R. Differential Effects of Statins on A-Beta in Cerebrospinal Fluid. Merck - AFAR, Funded 07/01/2003.

121.   Zhang J. Biomarkers for Parkinson's Disease (PD) and PD Dementia. NIH/NIA, R01 AG025327, Funded 09/01/2004.

122.   Zhang J. CSF Biomarkers for Parkinson's Disease. Michael J Fox Foundation, Funded 07/01/2005.


   Principal Investigator: Norman Foster (NACC Project #2000-04)
   Title: Collaborative PET Imaging Study
   Lead Institutions: University of Michigan
 
       Publications
123.   Foster NL, Barbas NR, Heidebrink JL, Turner RS, Clark CM, Jagust WJ, Arnold SE, DeCarli CS, Koeppe RA and Higdon R. Adding FDG-PET to clinical information improves the accuracy of dementia diagnosis. Neurobiol Aging, 25:372, Published 2004. (Abstract)

124.   Foster NL, Heidebrink JL, Clark CM, Jagust WJ, Arnold SE, Barbas NR, DeCarli C, Turner RS, Koeppe RA, Higdon R, Minoshima S. Inter-rater reliability and diagnostic accuracy of FDG-PET is superior to clinical history and examination in dementia. Neurobiol Aging, 23:S353, Published 2002. (Abstract)

125.   Foster NL, Heidebrink JL, Clark CM, Jagust WJ, Arnold SE, Barbas NR, DeCarli CS, Turner RS, Koeppe RA, Higdon R, Minoshima S. FDG-PET improves accuracy in distinguishing frontotemporal dementia and Alzheimer's disease. Brain, 130:2616-2635, Published 2007.

126.   Foster NL, Koeppe RA, Rogers V, Minoshima S, Clark CM, Jagust WJ, Arnold SE, Barbas NR, DeCarli CS, Heidebrink JL, Turner RS, Higdon R. A multi-center trial to evaluate the clinical utility of FDG-PET. 2nd meeting of the Alzheimer's Imaging Consortium, Accepted 2002. (Abstract)

127.   Foster NL, Koeppe RE, Giordani BJ, Nichols TE, Lieberman AP. Variations of the phenotype in frontotemporal dementias. In: Cummings J, Hardy J, Poncet M, Christen Y, eds Genotype - Proteotype - Phenotype Relationships in Neurodegenerative Diseases Berlin: Spinger-Verla, 139-152, Published 2005.

128.   Foster NL, Poynter JA, Heidebrink JL, Jagust WJ, Clark CM, Turn RS, Barbas NR, Arnold SE, DeCarli C, Koeppe RA, Higdon R, Minoshima S. Good diagnostic inter-rater reliability in a multicenter study of FDG-PET in the evaluation of dementia. Neurology, 58:S3, Published 2002. (Abstract)

129.   Foster NL. FDG PET in the Diagnosis of Frontotemporal Dementia. Biol Psychiatry, 57:45, Published 2005. (Abstract)

130.   Foster NL. Validating FDG-PET as a biomarker for frontotemporal dementia. Exp Neurol, 184:S2-8, Published 2003.

131.   Gabel MJ, Foster NL, Heidebrink JL, Higdon R, Aizenstein HJ, Arnold SE, Barbas NR, Boeve BF, Burke JR, Clark CM, Dekosky ST, Farlow MR, Jagust WJ, Kawas CH, Koeppe RA, Leverenz JB, Lipton AM, Peskind ER, Turner RS, Womack KB, Zamrini EY. Validation of consensus panel diagnosis in dementia. Arch Neurol, 67:1506-1512, Published 2010, PMC3178413.

132.   Heidebrink JL, Barbas NR, Turner RS, Clark CM, Jagust WJ, Arnold SE, DeCarli CS, Koeppe RA, Higdon R, Foster NL. FDG-PET improves differential diagnosis of dementia when clinical history and examination are ambiguous. Neurobiol Aging, 25:370, Published 2004. (Abstract)

133.   Womack KB, Diaz-Arrastia R, Aizenstein HJ, Arnold SE, Barbas NR, Boeve BF, Clark CM, DeCarli CS, Jagus, WJ, Leverenz JB, Peskind ER, Turner S, Zamrini EY, Heidebrink JL, Burke JR, DeKosky ST, Farlow MR, Gabel MJ, Higdon R, Kawas CH, Koeppe RA, Lipton AM, Foster NL. Temporoparietal Hypometabolism in Frontotemporal Lobar Degeneration and Associated Imaging Diagnostic Errors. Arch Neurol, 68:329-337, Published 2011, PMC3058918.

134.   Higdon R, Foster NL, Koeppe RA, DeCarli CS, Jagust WJ, Clark CM, Barbas NR, Arnold SE, Turner RS, Heidebrink JL, Minoshima S. A comparison of classification methods for differentiating fronto-temporal dementia from Alzheimer's disease using FDG-PET imaging. Stat Med, 23:315-326, Published 2004.

 
       Externally-Funded Awards
135.   Foster N. Pilot Collaborative PET Imaging Study. NIH/NIA, R01 AG022394, Funded 09/30/2003.


   Principal Investigator: Douglas Galasko, MD (NACC Project #2000-05)
   Title: Clinico-pathologic Studies in Fronto-Temporal Dementia
   Lead Institutions: University of California, San Diego
 
       Publications
136.   Rascovsky K, Salmon D, Clark C, DeCarli C, Graff-Radford N, Leverenz J, Galasko D. Rate of progression differs in frontotemporal dementia and Alzheimer's disease. Neurology, 62:A344, Published 2004. (Abstract)

137.   Rascovsky K, Salmon DP, Lipton AM, Leverenz JB, DeCarli C, Jagust WJ, Clark CM, Mendez MF, Tang-Wai DF, Graff-Radford NR, Galasko D. Rate of progression differs in frontotemporal dementia and Alzheimer disease. Neurology, 65:397-403, Published 2005.


   Principal Investigator: John Growdon, MD (NACC Project #2000-06)
   Title: Consortium on Alzheimer’s Genetics
   Lead Institutions: Massachusetts ADRC
 
       Publications
138.   Bertram L, Hiltunen M, Parkinson M, Ingelsson M, Lange C, Ramasamy K, Mullin K, Menon R, Sampson AJ, Hsiao MY, Elliott KJ, Velicelebi G, Moscarillo T, Hyman BT, Wagner SL, Becker KD, Blacker D, Tanzi RE. Family-based association between Alzheimer's disease and variants in UBQLN1. N Engl J Med, 352:884-894, Published 2005.

139.   Bertram L, Hsiao M, Mullin K, Parkinson M, Menon R, Moscarillo TJ, Blacker D, Tanzi RE. ACAT1 is not associated with Alzheimer's disease in two independent family-based samples. Mol Psychiatry, 10:522-524, Published 2005.

140.   Bertram L, Parkinson M, McQueen MB, Mullin K, Hsiao M, Menon R, Moscarillo TJ, Blacker D, Tanzi RE. Further evidence for LBP-1c/CP2/LSF association in Alzheimer's disease families. J Med Genet, 42:857-862, Published 2005.

141.   Bertram L, Tanzi RE. Author reply: The Ubiquitin 1 gene and Alzheimer's disease. N Engl J Med, 352:26, Published 2005.

142.   Mullin K, Bertram L, Moscarillo T, Becker KD, Wang C, Growdon J, Blacker D, Tanzi RE, tCAGS Group. Genetic association within the IDE region on chromosome 10-the consortium on Alzheimer's genetics (CAG). 33rd annual meeting of the Society for Neuroscience, Accepted 2003. (Abstract)


   Principal Investigator: Michael Grundman, MD PhD (NACC Project #3)
   Title: A Multi-Center Collaboration to Evaluate Candidate Agents for AD Prevention Trials
   Lead Institutions: University of California, San Diego
 
       Publications
143.   Grundman M. Antioxidant Supplements are Associated with a Lower Risk of Developing Mild Cognitive Impairment or Alzheimer's Disease among Healthy Elderly Volunteers. Neuroscience, 546:516, Published 2001. (Abstract)

144.   Grundman M. The Alzheimer's Disease Centers' Neuropsychological Database Initiative: A Resource for Alzheimer's Disease Prevention Trials. In: Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics New York: Wiley, Published 2001.

145.   Ji M, Xiong C, Grundman M. Hypothesis testing of a change point during cognitive decline among Alzheimer's disease patients. J Alzheimers Dis, 5:375-382, Published 2003.


   Principal Investigator: Neil Kowall, MD (NACC Project #5)
   Title: Collaborative Study Group on Vascular Pathology
   Lead Institutions: Boston University
 
       Publications
146.   McKee A, Au R, Cabral H, Auerbach S, Green R, Kowall N, Wolf P. Microvascular lesions distinguish cognitively impaired subjects without Alzheimer's disease from unimpaired subjects: Findings from the Framingham Heart Study. Vas Cog, Accepted 2005. (Abstract)

147.   Rieckmann A, Gomperts SN, Johnson KA, Growdon JH, Van Dijk KR. Putamen-midbrain functional connectivity is related to striatal dopamine transporter availability in patients with Lewy body diseases. Neuroimage Clin, 8:554-559, Published 2015, PMC4484547.

148.   Yip AG, McKee A, Wells J, Green RC, Young H, Cupples LA, Farrer LA. APOE, vascular pathology, and the AD brain. Neurobiol Aging, 25:403, Published 2004. (Abstract)

149.   Yip AG, McKee AC, Green RC, Wells J, Young H, Cupples LA,Farrer LA. APOE, vascular pathology, and the AD brain. Neurology, 65:2259-265, Published 2005.

 
       Externally-Funded Awards
150.   Wolf P. Epidemiology of dementia in the Framingham cohort. NIH/NIA, R01 AG08122, Funded 06/01/2000.


   Principal Investigator: Bernardino Ghetti (NACC Project #8)
   Title: Identification of Atypical Dementias from Neuropathology to Molecular Etiology
   Lead Institutions: Indiana University
 
       Publications
151.   Adamec E, Murrell JR, Takao M, Hobbs W, Nixon RA, Ghetti B, Vonsattel JP. P301L tauopathy: confocal immunofluorescence study of perinuclear aggregation of the mutated protein. J Neurol Sci, 200:85-93, Published 2002.

152.   Azzarelli B, Miravalle L, Olson J, Ghetti B, Biller J, Vidal R. CADASIL: A familial form of cerebrovascular disease leading to dementia Identification of two new families and a novel mutation. Neurology, 60:A368-A369, Published 2003. (Abstract)

153.   Byrne NP, Ito M, Takao M, Miravalle L, Murrell JR, Ghetti B, Powers JM. A novel form of senile dementia neuropathologically characterized by frontotemporal degeneration and leukoencephalopathy associated with a severe tau deposition predominantly in glia. J Neuropathol Exper Neurol, 61:460, Published 2002. (Abstract)

154.   Cochran EJ, Murrell JR, Fox J, Ringman J, Ghetti B. A novel mutation in the presenilin 1 (PS1) gene (A431E) associated with early-onset Alzheimer disease. J Neuropathol Exper Neurol, 60:544, Published 2001. (Abstract)

155.   Davis RL, Shrimpton AE, Carrell RW, Lomas DA, Gerhard L, Baumann B, Lawrence DA, Yepes M, Kim TS, Ghetti B, Piccardo P, Takao M, Lacbawan F, Muenke M, Sifers RN, Bradshaw CB, Kent PF, Collins GH, Larocca D, Holohan PD. Association between conformational mutations in neuroserpin and onset and severity of dementia. Lancet, 359:2242-2247, Published 2002.

156.   Delisle MB, Uro-Coste E, Rascol O, Sinani V, Piccardo P, Takao M, Vidal R, Ghetti B. A neurodegenerative disease with intranuclear deposits: clinical and neuropathologic studies. J Neuropathol Exper Neurol, 60:514, Published 2001. (Abstract)

157.   Farlow MR, Murrell JR, Unverzagt FW, Phillips M, Takao M, Hulette C, Ghetti B. Familial Alzheimer's Disease with Spastic Paraparesis Associated with a Mutation at Codon 261 of the Presenilin 1 Gene Therapeutics. In: Iqbal K, Sisodia SS, Winblad B, eds Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics Chichester: John Wiley and Sons Ltd, 53-60, Published 2001.

158.   Ghetti B, Piccardo P, Parisi J, Takao M, Dlouhy S, Cochran EJ, Fox JH. Gerstmann-Straussler-Scheinker (GSS) disease with neurofibrillary tangles and PrP-amyloid plaques: a new family. J Neuropathol Exper Neurol, 60:537, Published 2001. (Abstract)

159.   Hattab EM, Murrell JR, Yamaguchi K, Unverzagt FW, Foroud T, Miravalle L, Takao M, Hulette C, Vidal R, Farlow MR, Ghetti B. Widespread Abeta angiopathy, cotton wool plaques and pyramidal tract degeneration are the main neuropathologic features associated with the V261F mutation in the Presenilin 1 gene. J Neuropathol Exper Neurol, 62, Published 2003. (Abstract)

160.   Miravalle L, Murrell JR, Takao M, Glazier B, Piccardo P, Vidal R, Ghetti B. Genetic mutations associated with presenile dementia. Neurobiol Aging, 23:S322, Published 2002. (Abstract)

161.   Miravalle L, Murrell JR, Takao M, Richardson R, Bassett SS, Crain B, Ghetti B. Hippocampal pathology in patients with FTDP-17 and a mutation in the intron following exon 10 (+16) of the tau gene. J Neuropathol Exper Neurol, 60:548, Published 2001. (Abstract)

162.   Murrell JF, Miravalle L, Foster NL, Albin R, Takao M, Ghetti B. Early-onset familial Alzheimer disease (AD) from the first American report: a presenilin 1 (PS1) mutation found in descendants. J Neuropathol Exper Neurol, 60:543, Published 2001. (Abstract)

163.   Murrell JR, Faber K, Alonso ME, Rasmussen A, Varpetian A, Macias MA, Cochran E, Gambetti P, Castellani RJ, Bauserman SC, Foroud T, Vidal R, Miravalle L, Ghetti B, Ringman JM. The A431E Presenilin 1 gene mutation associated with familial Alzheimer disease in individuals of Mexican descent: evidence for a founder effect. J Neuropathol Exper Neurol, 62, Published 2003. (Abstract)

164.   Piccardo P, William A, Dlouhy SR, Farlow MR, Takao M, Ghetti B. Two nonglycosylated prion protein (PrP) isoforms coexist within the same microregions in the brain of some individuals with sporadic Creutzfeldt-Jakob disease (sCJD). Exper Neurol, 60:549, Published 2001. (Abstract)

165.   Powers JM, Byrne NP, Ito M, Takao M, Yankopoulou D, Spillantini MG, Ghetti B. A novel leukoencephalopathy associated with tau deposits primarily in white matter glia. Acta Neuropathol, 106:181-187, Published 2003.

166.   Rascol O, Goizet C, Labauge P, Delisle MB, Vidal R, Calvas P, Ghetti B. A novel autosomic dominant movement disorder with intranuclear ferritin containing inclusions. Neurology, 60, Published 2003. (Abstract)

167.   Ringman JM, Jain V, Murrell J, Ghetti B, Cochran EJ. Human Gene Mutations: Gene Symbol: PSEN1. Hum Genetics, 109:242, Published 2001. (Abstract)

168.   Takao M, Ghetti B, Hayakawa I, Ikeda E, Fukuuchi Y, Miravalle L, Piccardo P, Murrell JR, Glazier BS, Koto A. A novel mutation (G217D) in the Presenilin 1 gene (PSEN1) in a Japanese family: presenile dementia and parkinsonism are associated with cotton wool plaques in the cortex and striatum. Acta Neuropathol, 104:155-170, Published 2002.

169.   Takao M, Ghetti B, Murrell JR, Unverzagt FW, Giaccone G, Tagliavini F, Bugiani O, Piccardo P, Hulette CM, Crain BJ, Farlow MR, Heyman A. Ectopic white matter neurons, a developmental abnormality that may be caused by the PSEN1 S169L mutation in a case of familial AD with myoclonus and seizures. J Neuropathol Exp Neurol, 60:1137-1152, Published 2001.

170.   Takao M, Ghetti B, Yoshida H, Piccardo P, Narain Y, Murrell JR, Vidal R, Glazier BS, Jakes R, Tsutsui M, Spillantini MG, Crowther RA, Goedert M, Koto A. Early-onset dementia with Lewy bodies. Brain Pathol, 14:137-147, Published 2004.

171.   Takao M, Hayakawa I, Ikeda E, Koto A, Fukuuchi Y, Miravalle L, Piccardo P, Murrell JR, Ghetti B. A novel mutation (G217D) in the presenilin 1(PS1) gene associated with familial presenile dementia and Parkinsonism in a Japanese family. J Neuropathol Exp Neurol, 60:543, Published 2001. (Abstract)

172.   Takao M, Murrell J, Piccardo P, Unverzagt FW, Farlow MR, Vidal R, Miravalle L, Glazier BS, Stuck J, Foroud T, Ghetti B. Presenilin 1 mutation P264L associated with presenile dementia, cotton wool plaques and diffuse Lewy bodies. J Neuropathol Exp Neurol, 61:7, Published 2002. (Abstract)

173.   Takao M, Narain Y, Spillantini MG, Piccardo P, Murrell JR, Vidal R, Crowther RA, Goedert M, Ghetti B, Koto A. Atypical form of diffuse Lewy body disease with onset at 13 years of age. J Neuropathol Exp Neurol, 61:459, Published 2002. (Abstract)

174.   Takao M, Piccardo P, Murrell J, Miravalle L, Vidal R, Brashear A, Foster N, Towfighi J, Farlow M, Unverzagt F, Koto A, Hulette C, Conneally PM, Foroud T, Cochran E, Glazier B. Neuropathologic heterogeneity associated with Presenilin 1 gene mutations. Neurobiol Aging, 23:S417, Published 2002. (Abstract)

175.   Vidal R, Azzarelli B, Miravalle L, Olson J, Nukes T, Biller J, Ghetti B. CADASIL in two North American Caucasian families. J Neuropathol Exper Neurol, 62, Published 2003. (Abstract)

176.   Vidal R, Benson MD, Liepnieks JM, Yazaki M, Miravalle L, Uro-Coste E, Delisle MB, Ghetti B. A neurodegenerative disease with intranuclear protein deposits: electron microscopic and biochemical studies. J Neuropathol Exper Neurol, 60:515, Published 2001. (Abstract)

177.   Vidal R, Delisle MB, Ghetti B. Neurodegeneration caused by proteins with an aberrant carboxyl-terminus. J Neuropathol Exp Neurol, 63:787-800, Published 2004.

178.   Vidal R, Delisle MB, Liepnieks JJ, Uro-Coste E, Yazaki M, Rascol O, Siani V, Miravalle L, Takao M, Piccardo P, Calvas P, Benson MD, Ghetti B. CNS and systemic deposition of ferritin and iron associated with a novel autosomal dominant neurodegenerative disease. J Neurosci, 573:14, Published 2001. (Abstract)

179.   Vidal R, Delisle MB, Rascol O, Ghetti B. Hereditary ferritinopathy. J Neurol Sci, 207:110-111, Published 2003.

180.   Vidal R, Delisle MB, Takao M, Miravalle L, Uro-Coste E, Liepnieks JJ, Yazaki M, Siani V, Piccardo P, Calvas P, Murrell J, Benson MD, Rascol O, Ghetti B. A familial adult-onset autosomal dominant neurodegenerative disease associated with cytoplasmic and intranuclear accumulation of ferritin. Neurobiol Aging, 23:S205, Published 2002. (Abstract)

181.   Vidal R, Delisle MB, Takao M, Miravalle L, Uro-Coste E, Liepnieks JJ, Yazaki M, Siani V, Piccardo P, Calvas P, Murrell JR, Benson MD, Rascol O, Ghetti B. A familial autosomal dominant disease associated with intracytoplasmic and intranuclear ferritin accumulation. Clin Neuropathol, 21:136-137, Published 2002. (Abstract)

182.   Vidal R, Delisle MB, Takao M, Miravalle L, Uro-Coste E, Liepnieks JJ, Yazaki M, Sinai V, Piccardo P, Calvas P, Benson MD, Rascol, O, Ghetti B. Autosomal dominant neurodegenerative disease associated with accumulation of ferritin. J Neuropathol Exper Neurol, PG55, Published 2002. (Abstract)

183.   Vidal R, Delisle MB, Takao M, Uro-Coste E, Calvas P, Benson MD, Miravalle L, Rascol O, Ghetti B. Intracellular ferritin accumulation in neural and extraneural tissue characterizes a neurodegenerative disease associated with a TC insertion in exon 4 of the Ferritin Light Polypeptide (FTL) gene. Neurology, 62:A177, Published 2004. (Abstract)

184.   Vidal R, Ghetti B, Takao M, Brefel-Courbon C, Uro-Coste E, Glazier BS, Siani V, Benson MD, Calvas P, Miravalle L, Rascol O, Delisle MB. Intracellular ferritin accumulation in neural and extraneural tissue characterizes a neurodegenerative disease associated with a mutation in the ferritin light polypeptide gene. J Neuropathol Exp Neurol, 63:363-380, Published 2004.

185.   Vidal R, Piccardo P, Miravalle L, Takao M, Frangione B, Ghetti B. Senile dementia associated with Ab angiopathy and tau perivascular pathology but not neuritic plaques in patients homozygous for the APOE 4 allele. J Neuropathol Exper Neurol, PG54, Published 2002. (Abstract)

186.   Yamaguchi K, Miravalle L, Piccardo P, Murrell JR, Foroud T, Vidal R, Unverzagt FW, Farlow MR, Ghetti B. Phenotypic variability associated with the Presenilin 2 N141I mutation in individuals of Volga-German descent. J Neuropathol Exper Neurol, 62:543, Published 2003. (Abstract)

 
       Externally-Funded Awards
187.   Vidal R. Ferritin Induced Neurodegeneration. NIH/NINDS, R01 NS050227, Funded 07/15/2005.


   Principal Investigator: Chris Clark (NACC Project #Clark)
   Title: Does the onset of AD differ in Latinos
   Lead Institutions: Univ of Pennsylvania
 
       Publications
188.   Clark CM, DeCarli C, Mungas D, Chui H, Higdon R, Nunez J, Fernandez H, Negron M, Manly J, Hernandez I, Ferris S, Perez A, Torres M, Ewbank D, Glosser G, van Belle G. Latino patients with Alzheimer's disease have an earlier age of symptom onset compared to Anglos. Neurobiol Aging, 25:S106, Published 2004. (Abstract)

189.   Clark CM, DeCarli C, Mungas D, Chui HI, Higdon R, Nunez J, Fernandez H, Negron M, Manly J, Ferris S, Perez A, Torres M, Ewbank D, Glosser G, van Belle G. Earlier onset of Alzheimer disease symptoms in Latino individuals compared with Anglo individuals. Arch Neurol, 62:774-778, Published 2005.


   Principal Investigator: Michael Hughes (NACC Project #Hughes)
   Title: ADC Collaborative Networks
   Lead Institutions: Univ of Pennsylvania
 
       Publications
190.   Hughes ME, Peeler J, Hogenesch JB, Trojanowski JQ. The Growth and Impact of Alzheimer Disease Centers as Measured by Social Network Analysis. JAMA Neurol, 71:412-420, Published 2014, PMC4096555.


NACC - ADC Collaboration in External Studies(RFA-AG-03-005 and RFA-AG-05-006)(by project): (TOTAL of 73)

   Principal Investigator: Carl Cotman, PhD
   Title: Brain Aging and Gene Expression Patterns Using Microarrays
   Agency: NIA - RO1 AG023173
   Date Funded: 9/1/2003
 
       Publications
1.   Berchtold NC, Cribbs DH, Coleman PD, Rogers J, Head E, Kim R, Beach T, Miller C, Troncoso J, Trojanowski JQ, Zielke HR, Cotman CW. Gene expression changes in the course of normal brain aging are sexually dimorphic. Proc Natl Acad Sci U S A, 105:15605-15610, Published 2008, PMC2563070.

2.   Pan F, Chiu CH, Pulapura S, Mehan MR, Nunez-Iglesias J, Zhang K, Kamath K, Waterman MS, Finch CE, Zhou XJ. Gene Aging Nexus: a web database and data mining platform for microarray data on aging. Nucleic Acids Res, 35:D756-759, Published 2007, PMC1669755.

3.   Parachikova A, Agadjanyan MG, Cribbs DH, Blurton-Jones M, Perreau V, Rogers J, Beach TG, Cotman CW. Inflammatory changes parallel the early stages of Alzheimer disease. Neurobiol Aging, 28:1821-2833, Published 2007, PMC2198930.


   Principal Investigator: Douglas Galasko, MD
   Title: Biomarkers in Aging, MCI and Alzheimer’s Disease
   Agency: NIA - RO1 AG023185
   Date Funded: 9/1/2003
 
       Publications
4.   Portelius E, Bogdanovic N, Gustavsson MK, Volkmann I, Brinkmalm G, Zetterberg H, Winblad B, Blennow K. Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer's disease. Acta Neuropathol, 120:185-193, Published 2010, PMC3568930.

5.   Li G, Peskind ER, Millard SP, Chi P, Sokal I, Yu CE, Bekris LM, Raskind MA, Galasko DR, Montine TJ. Cerebrospinal fluid concentration of brain-derived neurotrophic factor and cognitive function in non-demented subjects. PLoS One, 4:e5424, Published 2009, PMC2671606.

6.   Petrie EC, Cross DJ, Galasko D, Schellenberg GD, Raskind MA, Peskind ER, Minoshima S. Preclinical evidence of Alzheimer changes: convergent cerebrospinal fluid biomarker and fluorodeoxyglucose positron emission tomography findings. Arch Neurol, 66:632-637, Published 2009, PMC2718788.

7.   Peskind ER, Li G, Shofer J, Quinn JF, Kaye JA, Clark CM, Farlow MR, DeCarli C, Raskind MA, Schellenberg GD, Lee VM, Galasko D. Age and apolipoprotein E*4 allele effects on cerebrospinal fluid beta-amyloid 42 in adults with normal cognition. Arch Neurol, 63:936-939, Published 2006.

8.   Peskind ER, Riekse R, Quinn JF, Kaye J, Clark CM, Farlow MR, Decarli C, Chabal C, Vavrek D, Raskind MA, Galasko D. Safety and acceptability of the research lumbar puncture. Alzheimer Dis Assoc Disord, 19:220-225, Published 2005.


   Principal Investigator: Dietrich Stephan, PhD
   Title: Neurogenomics of Alzheimer’s Disease and Aging
   Agency: NIA - RO1 AG023193
   Date Funded: 9/1/2003
 
       Publications
9.   Liang WS, Chen K, Lee W, Sidhar K, Corneveaux JJ, Allen AN, Myers A, Villa S, Meechoovet B, Pruzin J, Bandy D, Fleisher AS, Langbaum JB, Huentelman MJ, Jensen K, Dunckley T, Caselli RJ, Kaib S, Reiman EM. Association between GAB2 haplotype and higher glucose metabolism in Alzheimer's disease-affected brain regions in cognitively normal APOEepsilon4 carriers. Neuroimage, 54:1896-1902, Published 2011, PMC3010232.

10.   Azorsa DO, Robeson RH, Frost D, Meec hoovet B, Brautigam GR, Dickey C, Beaudry C, Basu GD, Holz DR, Hernandez JA, Bisanz KM, Gwinn L, Grover A, Rogers J, Reiman EM, Hutton M, Stephan DA, Mousses S, Dunckley T. High-content siRNA screening of the kinome identifies kinases involved in Alzheimer's disease-related tau hyperphosphorylation. BMC Genomics, 11:25, Published 2010, PMCID2820455.

11.   Corneveaux JJ, Liang WS, Reiman EM, Webster JA, Myers AJ, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Craig DW, Coon KD, Dunckley T, Bandy D, Lee W, Chen K, Beach TG, Mastroeni D, Grover A, Ravid R, Sando SB, Aasly JO, Heun R, Jessen F, Kolsch H, Rogers J, Hutton ML, Melquist S, Petersen RC, Alexander GE, Caselli RJ, Papassotiropoulos A, Stephan DA, Huentelman MJ. Evidence for an association between KIBRA and late-onset Alzheimer's disease. Neurobiol Aging, 31:901-909, Published 2010, PMCID2913703.

12.   Corneveaux JJ, Myers AJ, Allen AN, Pruzin JJ, Ramirez M, Engel A, Nalls MA, Chen K, Lee W, Chewning K, Villa SE, Meechoovet HB, Gerber JD, Frost D, Benson HL, O'Reilly S, Chibnik LB, Shulman JM, Singleton AB, Craig DW, Van Keuren-Jensen KR, Dunckley T, Bennett DA, De Jager PL, Heward C, Hardy J, Reiman EM, Huentelman MJ. Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Hum Mol Genet, 19:3295-3301, Published 2010, PMC2908469.

13.   Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Ramsey K, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette CM, Schmechel D, Reiman EM, Rogers J, Stephan DA. Neuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathology. Neurobiol Aging, 31:549-566, Published 2010, PMC2844804.

14.   Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Ramsey K, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette CM, Schmechel D, Reiman EM, Rogers J, Stephan DA. Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set. Physiol Genomics, 33:240-256, Published 2008, PMC2826117.

15.   Liang WS, Reiman EM, Valla J, Dunckley T, Beach TG, Grover A, Niedzielko TL, Schneider LE, Mastroeni D, Caselli R, Kukull W, Morris JC, Hulette CM, Schmechel D, Rogers J, Stephan DA. Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons. Proc Natl Acad Sci U S A, 105:4441-4446, Published 2008, PMC2393743.

16.   Coon KD, Myers AJ, Craig DW, Webster JA, Pearson JV, Lince DH, Zismann VL, Beach TG, Leung D, Bryden L, Halperin RF, Marlowe L, Kaleem M, Walker DG, Ravid R, Heward CB, Rogers J, Papassotiropoulos A, Reiman EM, Hardy J, Stephan DA. A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. J Clin Psychiatry, 68:613-618, Published 2007.

17.   Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Walker DG, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette C, Schmechel D, Alexander GE, Reiman EM, Rogers J, Stephan DA. Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. Physiol Genomics, 28:311-322, Published 2007, PMC2259385.

18.   Reiman EM, Webster JA, Myers AJ, Hardy J, Dunckley T, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Huentelman MJ, Craig DW, Coon KD, Liang WS, Herbert RH, Beach T, Rohrer KC, Zhao AS, Leung D, Bryden L, Marlowe L, Kaleem M, Mastroeni D, Grover A, Heward CB, Ravid R, Rogers J, Hutton ML, Melquist S, Petersen RC, Alexander GE, Caselli RJ, Kukull W, Papassotiropoulos A, Stephan DA. GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers. Neuron, 54:713-720, Published 2007, PMC2587162.

19.   Reiman EM. Linking brain imaging and genomics in the study of Alzheimer's disease and aging. Ann N Y Acad Sci, 1097:94-113, Published 2007.

20.   Coon KD, Siegel AM, Yee SJ, Dunckley TL, Mueller C, Nagra RM, Tourtellotte WW, Reiman EM, Papassotiropoulos A, Petersen FF, Stephan DA, Kirsch WM. Preliminary demonstration of an allelic association of the IREB2 gene with Alzheimer's disease. J Alzheimers Dis, 9:225-233, Published 2006, PMC1555623.

21.   Dunckley T, Beach TG, Ramsey KE, Grover A, Mastroeni D, Walker DG, LaFleur BJ, Coon KD, Brown KM, Caselli R, Kukull W, Higdon R, McKeel D, Morris JC, Hulette C, Schmechel D, Reiman EM, Rogers J, Stephan DA. Gene expression correlates of neurofibrillary tangles in Alzheimer's disease. Neurobiol Aging, 27:1359-1371, Published 2006, PMC2259291.

22.   Papassotiropoulos A, Fountoulakis M, Dunckley T, Stephan DA, Reiman EM. Genetics, transcriptomics, and proteomics of Alzheimer's disease. J Clin Psychiatry, 67:652-670, Published 2006.


   Principal Investigator: David Knopman, MD
   Title: Frontotemporal Dementia: Developing Drug Trial methods
   Agency: NIA - RO1 AG023195
   Date Funded: 9/1/2003
 
       Publications
23.   Bei H, Ross L, Neuhaus J, Knopman D, Kramer J, Boeve B, Caselli RJ, Graff-Radford N, Mendez MF, Miller BL, Boxer AL. Off-label medication use in frontotemporal dementia. Am J Alzheimers Dis Other Demen, 25:128-133, Published 2010, PMC2862544.

24.   Delucchi KL. MRS in presymptomatic MAPT mutation carriers: a potential biomarker for tau-mediated pathology. Neurology, 75:771-778, Published 2010, PMC2938968.

25.   Molano J, Boeve B, Ferman T, Smith G, Parisi J, Dickson D, Knopman D, Graff-Radford N, Geda Y, Lucas J, Kantarci K, Shiung M, Jack C, Silber M, Pankratz VS, Petersen R. Mild cognitive impairment associated with limbic and neocortical Lewy body disease: a clinicopathological study. Brain, 133:540-556, Published 2010, PMC2822633.

26.   Pakhomov SV, Smith GE, Chacon D, Feliciano Y, Graff-Radford N, Caselli R, Knopman DS. Computerized analysis of speech and language to identify psycholinguistic correlates of frontotemporal lobar degeneration. Cogn Behav Neurol, 23:165-177, Published 2010, PMC3365864.

27.   Vemuri P, Wiste HJ, Weigand SD, Knopman DS, Trojanowski JQ, Shaw LM, Bernstein MA, Aisen PS, Weiner M, Petersen RC, Jack CR Jr. Serial MRI and CSF biomarkers in normal aging, MCI, and AD. Neurology, 75:143-151, Published 2010, PMC2905929.

28.   Whitwell JL, Avula R, Senjem ML, Kantarci K, Weigand SD, Samikoglu A, Edmonson HA, Vemuri P, Knopman DS, Boeve BF, Petersen RC, Josephs KA, Jack, CR Jr. Gray and white matter water diffusion in the syndromic variants of frontotemporal dementia. Neurology, 74:1279-1287, Published 2010, PMC2860485.

29.   Whitwell JL, Jack CR Jr, Boeve BF, Parisi JE, Ahlskog JE, Drubach DA, Senjem ML, Knopman DS, Petersen RC, Dickson DW, Josephs KA. Imaging correlates of pathology in corticobasal syndrome. Neurology, 75:1879-1887, Published 2010, PMC2995388.

30.   Josephs KA, Whitwell JL, Knopman DS, Boeve BF, Vemuri P, Senjem ML, Parisi JE, Ivnik RJ, Dickson DW, Petersen RC, Jack Jr CR. Two distinct subtypes of right temporal variant frontotemporal dementia. Neurology, 73:1443-1450, Published 2009, PMC2779005.

31.   Knopman DS, Jack CR, Jr, Kramer JH, Boeve BF, Caselli RJ, Graff-Radford NR, Mendez MF, Miller BL, Mercaldo ND. Brain and ventricular volumetric changes in frontotemporal lobar degeneration over 1 year. Neurology, 72:1843-1849, Published 2009, PMC2690986.

32.   Lesage SR, Mosley TH, Wong TY, Szklo M, Knopman D, Catellier DJ, Cole SR, Klein R, Coresh J, Coker LH, Sharrett AR. Retinal microvascular abnormalities and cognitive decline: the ARIC 14-year follow-up study. Neurology, 73:862-868, Published 2009, PMC2744282.

33.   Knopman DS, Kramer JH, Boeve BF, Caselli RJ, Graff-Radford NR, Mendez MF, Miller BL, Mercaldo N. Development of methodology for conducting clinical trials in frontotemporal lobar degeneration. Brain, 131:2957-2968, Published 2008, PMC2667989.

34.   Boeve BF, Silber MH, Saper CB, Ferman TJ, Dickson DW, Parisi JE, Benarroch EE, Ahlskog JE, Smith GE, Caselli RC, Tippman-Peikert M, Olson EJ, Lin SC, Young T, Wszolek Z, Schenck CH, Mahowald MW, Castillo PR, Del Tredici K, Braak H. Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease. Brain, 130:2770-2788, Published 2007.

35.   Boeve BF. Parkinson-related dementias. Neurol Clin, 25:761-781, Published 2007.

36.   Knopman DS, Boeve BS, Caselli RJ, Graff-Radford NR, Kramer JH, Mendez MF, Miller BL. Longitudinal tracking of FTLD: toward developing clinical trial methodology. Alzheimer Dis Assoc Disord, 21:S58-63, Published 2007.

37.   Boeve BF. A review of the non-Alzheimer dementias. J Clin Psychiatry, 67:1985-2001, Published 2006.

38.   Gass J, Cannon A, Mackenzie IR, Boeve B, Baker M, Adamson J, Crook R, Melquist S, Kuntz K, Petersen R, Josephs K, Pickering-Brown SM, Graff-Radford N, Uitti R, Dickson D, Wszolek Z, Gonzalez J, Beach TG, Bigio E, Johnson N, Weintraub S, Mesulam M, White CL, 3rd, Woodruff B, Caselli R, Hsiung GY, Feldman H, Knopman D, Hutton M, Rademakers R. Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration. Hum Mol Genet, 15:2988-3001, Published 2006.

39.   Josephs KA, Petersen RC, Knopman DS, Boeve BF, Whitwell JL, Duffy JR, Parisi JE, Dickson, DW. Clinicopathologic analysis of frontotemporal and corticobasal degenerations and PSP. Neurology, 66:41-48, Published 2006.

40.   Knopman DS, Boeve BF, Parisi JE, Dickson DW, Smith GE, Ivnik RJ, Josephs KA, Petersen RC. Antemortem diagnosis of frontotemporal lobar degeneration. Ann Neurol, 57:480-488, Published 2005.


   Principal Investigator: Thomas Montine, MD, PhD
   Title: Characterization of DLB: A Collaborative Study
   Agency: NIA - RO1 NS048595
   Date Funded: 9/1/2003
 
       Publications
41.   Wang LY, Leverenz JB, Larson EB, Vavrek DA, Kukull WA, McCormick W, Bowen JD, Teri L, Montine T, Tsuang DW. Cognitive impairment in older adults without dementia: clinical and pathologic outcomes in a community-based sample. J Geriatr Psychiatry Neurol, 22:256-265, Published 2009, PMC2783244.

42.   Bekris LM, Millard SP, Galloway NM, Vuletic S, Albers JJ, Li G, Galasko DR, DeCarli C, Farlow MR, Clark CM, Quinn JF, Kaye JA, Schellenberg GD, Tsuang D, Peskind ER, Yu CE. Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels. J Alzheimers Dis, 13:255-266, Published 2008, PMC3192652.

43.   Leverenz JB, Hamilton RL, Tsuang DW, Schantz A, Vavrek D, Larson EB, Kukull WA, Lopez OL, Galasko D, Masliah E, Kaye J, Nixon R, Clark C, Trojanowski J, Montine TJ. Empiric refinement of the pathologic assessment of Lewy-related pathology in the dementia patient. Brain Pathol, 18:220-224, Published 2008, PMC2689097.

44.   VanRollins M, Woltjer RL, Yin H, Morrow JD, Montine TJ. F2-dihomo-isoprostanes arise from free radical attack on adrenic acid. J Lipid Res, 49:995-1005, Published 2008, PMC2311438.

45.   Leverenz JB, Umar I, Wang Q, Montine TJ, McMillan PJ, Tsuang DW, Jin J, Pan C, Shin J, Zhu D, Zhang J. Proteomic identification of novel proteins in cortical lewy bodies. Brain Pathol, 17:139-145, Published 2007.

46.   Sonnen JA, Larson EB, Crane PK, Haneuse S, Li G, Schellenberg GD, Craft S, Leverenz JB, Montine TJ. Pathological correlates of dementia in a longitudinal, population-based sample of aging. Ann Neurol, 62:406-413, Published 2007.

47.   Yang W, Woltjer RL, Sokal I, Pan C, Wang Y, Brodey M, Peskind ER, Leverenz JB, Zhang J, Perl DP, Galasko DR, Montine TJ. Quantitative proteomics identifies surfactant-resistant alpha-synuclein in cerebral cortex of Parkinsonism-dementia complex of Guam but not Alzheimer's disease or progressive supranuclear palsy. Am J Pathol, 171:993-1002, Published 2007, PMC1959487.

48.   Abdi F, Quinn JF, Jankovic J, McIntosh M, Leverenz JB, Peskind E, Nixon R, Nutt J, Chung K, Zabetian C, Samii A, Lin M, Hattan S, Pan C, Wang Y, Jin J, Zhu D, Li GJ, Liu Y, Waichunas D, Montine TJ, Zhang J. Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders. J Alzheimers Dis, 9:293-348, Published 2006.

49.   Leverenz JB, Fishel MA, Peskind ER, Montine TJ, Nochlin D, Steinbart E, Raskind MA, Schellenberg GD, Bird TD, Tsuang D. Lewy body pathology in familial Alzheimer disease - Evidence for disease- and mutation-specific pathologic phenotype. Arch Neurol, 63:370-376, Published 2006, PMC1892620.

50.   Tsuang DW, Riekse RG, Purganan KM, David AC, Montine TJ, Schellenberg GD, Steinbart EJ, Petrie EC, Bird TD, Leverenz JB. Lewy body pathology in late-onset familial Alzheimer's disease: A clinicopathological case series. J Alzheimers Dis, 9:235-242, Published 2006.

51.   Zabetian CP, Lauricella CJ, Tsuang DW, Leverenz JB, Schellenberg GD, Payami H. Analysis of the LRRK2 G2019S mutation in Alzheimer Disease. Arch Neurol, 63:156-157, Published 2006.

52.   Zaja-Milatovic S, Keene CD, Montine KS, Leverenz JB, Tsuang D, Montine TJ. Selective dendritic degeneration of medium spiny neurons in dementia with Lewy bodies. Neurology, 66:1591-1593, Published 2006.

53.   Kraybill ML, Larson EB, Tsuang DW, Teri L, McCormick WC, Bowen JD, Kukull WA, Leverenz JB, Cherrier MM. Cognitive differences in dementia patients with autopsy-verified AD, Lewy body pathology, or both. Neurology, 64:2069-2073, Published 2005, PMC1513627.

54.   Tsuang D, Simpson KL, Li G, Barnhart RL, Edland SD, Bowen J, McCormick W, Teri L, Nochlin D, Larson EB, Thompson ML, Leverenz JB. Evaluation of selection bias in an incident-based dementia autopsy case series. Alzheimer Dis Assoc Disord, 19:67-73, Published 2005, PMC1524825.

55.   Tsuang DW, Wilson RK, Lopez OL, Luedecking-Zimmer EK, Leverenz JB, DeKosky ST, Kamboh MI, Hamilton RL. Genetic association between the APOE*4 allele and Lewy bodies in Alzheimer disease. Neurology, 64:509-513, Published 2005, PMC1487185.

56.   Ohtake H, Limprasert P, Fan Y, Onodera O, Kakita A, Takahashi H, Bonner LT, Tsuang DW, Murray IV, Lee VM, Trojanowski JQ, Ishikawa A, Idezuka J, Murata M, Toda T, Bird TD, Leverenz JB, Tsuji S, La Spada AR. Beta-synuclein gene alterations in dementia with Lewy bodies. Neurology, 63:805-811, Published 2004, PMC1808539.

57.   Riekse RG, Leverenz JB, McCormick W, Bowen JD, Teri L, Nochlin D, Simpson K, Eugenio C, Larson EB, Tsuang D. Effect of vascular lesions on cognition in Alzheimer's disease: a community-based study. J Am Geriatr Soc, 52:1442-1448, Published 2004, PMC1487184.

58.   Tsuang DW, DiGiacomo L, Bird TD. Familial occurrence of dementia with Lewy bodies. Am J Geriatr Psychiatry, 12:179-188, Published 2004, PMC1482839.

59.   Bonner LT, Tsuang DW, Cherrier MM, Eugenio CJ, Du Jennifer Q, Steinbart EJ, Limprasert P, La Spada AR, Seltzer B, Bird TD, Leverenz JB. Familial dementia with Lewy bodies with an atypical clinical presentation. J Geriatr Psychiatry Neurol, 16:59-64, Published 2003.


   Principal Investigator: Patricia L, Kramer
   Title: Genetic Associations with Alzheimer-free Survival
   Agency: NIA - RO1 AG026916
   Date Funded: 7/1/2005
 
       Publications
60.   Kramer PL, Xu H, Woltjer RL, Westaway SK, Clark D, Erten-Lyons D, Kaye JA, Welsh-Bohmer KA, Troncoso JC, Markesbery WR, Petersen RC, Turner RS, Kukull WA, Bennett DA, Galasko D, Morris JC, Ott J. Alzheimer disease pathology in cognitively healthy elderly: A genome-wide study. Neurobiol Aging, 32:2113-22, Published 2011, PMC2990809.

61.   Kruer MC, Koch TK, Bourdette DN, Chabas D, Waubant E, Mueller S, Moscarello MA, Dalmau J, Woltjer RL, Adamus G. NMDA receptor encephalitis mimicking seronegative neuromyelitis optica. Neurology, 74:1473-1475, Published 2010, PMC2872802.

62.   Shervais S, Kramer PL, Westaway SK, Cox NJ, Zwick M. Reconstructability analysis as a tool for identifying gene-gene interactions in studies of human diseases. Stat Appl Genet Mol Biol, 9:Article 18, Published 2010, PMC2861311.

63.   Wang G, Yang Y, Ott J. Genome-wide conditional search for epistatic disease-predisposing variants in human association studies. Hum Hered, 70:34-41, Published 2010, PMC2912644.

64.   Hayes TL, Cobbinah K, Dishongh T, Kaye JA, Kimel J, Labhard M, Leen T, Lundell J, Ozertem U, Pavel M, Philipose M, Rhodes K, Vurgun S. A study of medication-taking and unobtrusive, intelligent reminding. Telemed J E Health, 15:770-776, Published 2009, PMC2998278.


   Principal Investigator: Daniel H. Geschwind
   Title: Identification of Novel Genetic Risk Factors for AD and FTD
   Agency: NIA - RO1 AG026938
   Date Funded: 9/1/2005
 
       Publications
65.   Coppola G, Wang Q, Davis-Turak J, Lee JJ, Klein E, Huang A, Rasheedi K, Karydas A, Rosen A, Varpetian A, Miller J, Poon W, LeBer I, Shapira J, Faber K, Beekly D, Cotman C, DeCarli C, Ringman J, Mendez M, Brice A, Foroud T, Kukull W, Chui H, Levey A, Miller B, Geschwind G. Genetic Investigation in Frontotemporal Dementia and Alzheimer's Disease: the GIFT Study. Dement Geriatr Cogn Disord, 30:50, Published 2010. (Abstract)

66.   Coppola G, Miller B, Levey A, Varpetian A, Chui H, DeCarli C, Cotman C, Bartzokis G, Mendez M, Kukull W, Foroud T, Geschwind D. Genetic investigation in frontotemporal dementia and Alzheimer's disease: The GIFT study. Neurology, 70:A242, Published 2008. (Abstract)

67.   Coppola G, Miller BL, Chui H, Varpetian A, Levey A, Cotman CW, DeCarli C, Mendez MF, Bartzokis G, Kukull WA, Foroud T, Geschwind DH. Genetic investigation in frontotemporal dementia and Alzheimer's disease: The GIFT study. Ann Neurol, 62:S525, Published 2007. (Abstract)

68.   Chen JA, Wang Q, Davis-Turak J, Li Y, Karydas AM, Hsu SC, Sears RL, Chatzopoulou D, Huang AY, Wojta KJ, Klein E, Lee J, Beekly DL, Boxer A, Faber KM, Haase CM, Miller J, Poon WW, Rosen A, Rosen H, Sapozhnikova A, Shapira J, Varpetian A, Foroud TM, Levenson RW, Levey AI, Kukull WA, Mendez MF, Ringman J, Chui H, Cotman C, DeCarli C, Miller BL, Geschwind DH, Coppola G. A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy. JAMA Neurol, 72:414-422, Published 2015, PMC4397175.

69.   Miller JA, Horvath S, Geschwind DH. Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways. Proc Natl Acad Sci U S A, 107:12698-12703, Published 2010, PMC2906579.

70.   Coppola G, Karydas A, Rademakers R, Wang Q, Baker M, Hutton M, Miller BL, Geschwind DH. Gene expression study on peripheral blood identifies progranulin mutations. Ann Neurol, 64:92-96, Published 2008, PMC2773201.

71.   Miller JA, Oldham MC, Geschwind DH. A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging. J Neurosci, 28:1410-1420, Published 2008, PMC2902235.

72.   Rademakers R, Baker M, Gass J, Adamson J, Huey ED, Momeni P, Spina S, Coppola G, Karydas AM, Stewart H, Johnson N, Hsiung GY, Kelley B, Kuntz K, Steinbart E, Wood EM, Yu CE, Josephs K, Sorenson E, Womack KB, Weintraub S, Pickering-Brown SM, Schofield PR, Brooks WS, Van Deerlin VM, Snowden J, Clark CM, Kertesz A, Boylan K, Ghetti B, Neary D, Schellenberg GD, Beach TG, Mesulam M, Mann D, Grafman J, Mackenzie IR, Feldman H, Bird T, Petersen R, Knopman D, Boeve B, Geschwind DH, Miller B, Wszolek Z, Lippa C, Bigio EH, Dickson D, Graff-Radford N, Hutton M. Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative. Lancet Neurol, 6:857-868, Published 2007.

73.   Karsten SL, Sang TK, Gehman LT, Chatterjee S, Liu J, Lawless GM, Sengupta S, Berry RW, Pomakian J, Oh HS, Schulz C, Hui KS, Wiedau-Pazos M, Vinters HV, Binder LI, Geschwind DH, Jackson GR. A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration. Neuron, 51:549-560, Published 2006.


Indirect NACC Support: (TOTAL of 24)
 
1.   Nordestgaard LT, Tybjaerg-Hansen A, Rasmussen KL, Nordestgaard BG, Frikke-Schmidt R. Genetic variation in clusterin and risk of dementia and ischemic vascular disease in the general population: cohort studies and meta-analyses of 362,338 individuals. BMC Med, 16:39, Published 2018.

2.   Cox CG, Gillen D, Grill JD. How do people with Mild Cognitive Impairment and their family members decide whether to enroll in prodromal Alzheimer's disease clinical trials?. Alzheimers Dement, 13:P1258, Published 2017. (Abstract)

3.   Croft CL, Cruz PE, Goodwin MS, Ceballos-Diaz C, Strang K, Chakrabarty P, Levites Y, Giasson BI, Golde TE. Targeting tau aggregation in brain slice culture models of tauopathies. Alzheimers Dement, 13:P1294, Published 2017. (Abstract)

4.   Escott-Price V, Myers AJ, Huentelman M, Hardy J. Polygenic risk score analysis of pathologically confirmed Alzheimer disease. Ann Neurol, 2:311-314, Published 2017, PMC5599118.

5.   Roe CM, Barco PP, Head DM, Ghoshal N, Selsor N, Babulal GM, Fierberg R, Vernon EK, Shulman N, Johnson A, Fague S, Xiong C, Grant EA, Campbell A, Ott BR, Holtzman DM, Benzinger TL, Fagan AM, Carr DB, Morris JC. Amyloid Imaging, Cerebrospinal Fluid Biomarkers Predict Driving Performance Among Cognitively Normal Individuals. Alzheimer Dis Assoc Disord, 31:69-72, Published 2017, PMC5085874.

6.   Tully HM, Kukull WA, Mueller BA. Clinical and Surgical Factors Associated With Increased Epilepsy Risk in Children With Hydrocephalus. Pediatr Neurol, 59:18-22, Published 2016, PMC in process.

7.   Tully HM, Wenger TL, Kukull WA, Morris JC, Doherty D, Dobyns WB. Anatomical configurations associated with posthemorrhagic hydrocephalus among premature infants with intraventricular hemorrhage. Neurosurg Focus, 41:E5, Published 2016, PMC5510987.

8.   Donovan NJ, Amariglio RE, Zoller AS, Rudel RK, Gomez-Isla T, Blacker D, Hyman BT, Locascio JJ, Johnson KA, Sperling RA, Marshall GA, Rentz DM. Subjective Cognitive Concerns and Neuropsychiatric Predictors of Progression to the Early Clinical Stages of Alzheimer Disease. Am J Geriatr Psychiatry, 22:1642-1651, Published 2014, PMC4145054.

9.   Chou SH, Shulman JM, Keenan BT, Secor EA, Buchman AS, Schneider J, Bennett DA, De Jager PL. Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations. Cerebrovasc Dis, 36:181-188, Published 2013, PMC3871868.

10.   Lu PH, Mendez MF, Lee GJ, Leow AD, Lee HW, Shapira J, Jimenez E, Boeve BB, Caselli RJ, Graff-Radford NR, Jack CR, Kramer JH, Miller BL, Bartzokis G, Thompson PM, Knopman DS.. Patterns of brain atrophy in clinical variants of frontotemporal lobar degeneration. Dement Geriatr Cogn Disord, 35:34-50, Published 2013, PMC3609420.

11.   Shulman JM, Chen K, Keenan BT, Chibnik LB, Fleisher A, Thiyyagura P, Roontiva A, McCabe C, Patsopoulos NA, Corneveaux JJ, Yu L, Huentelman MJ, Evans DA, Schneider JA, Reiman EM, De Jager PL, Bennett DA. Genetic susceptibility for Alzheimer disease neuritic plaque pathology. JAMA Neurol, 70:1150-1157, Published 2013, PMC3773291.

12.   De Jager PL, Shulman JM, Chibnik LB, Keenan BT, Raj T, Wilson RS, Yu L, Leurgans SE, Tran D, Aubin C, Anderson CD, Biffi A, Corneveaux JJ, Huentelman MJ, Rosand J, Daly MJ, Myers AJ, Reiman EM, Bennett DA, Evans DA. A genome-wide scan for common variants affecting the rate of age-related cognitive decline. Neurobiol Aging, 33:1017 e1011-1015, Published 2012, PMC3307898.

13.   Hamilton G, Killick R, Lambert JC, Amouyel P, Carrasquillo MM, Pankratz VS, Graff-Radford NR, Dickson DW, Petersen RC, Younkin SG, Powell JF, Wade-Martins R. Functional and genetic analysis of haplotypic sequence variation at the nicastrin genomic locus. Neurobiol Aging, 33:1848 e1-e13, Published 2012, PMC3683320.

14.   Keenan BT, Shulman JM, Chibnik LB, Raj T, Tran D, Sabuncu MR, Allen AN, Corneveaux JJ, Hardy JA, Huentelman MJ, Lemere CA, Myers AJ, Nicholson-Weller A, Reiman EM, Evans DA, Bennett DA, De Jager PL. A coding variant in CR1 interacts with APOE-epsilon4 to influence cognitive decline. Hum Mol Genet, 21:2377-2388, Published 2012, PMC3335317.

15.   Lim AS, Chang AM, Shulman JM, Raj T, Chibnik LB, Cain SW, Rothamel K, Benoist C, Myers AJ, Czeisler CA, Buchman AS, Bennett DA, Duffy JF, Saper CB, De Jager PL. A common polymorphism near PER1 and the timing of human behavioral rhythms. Ann Neurol, 72:324-334, Published 2012, PMC3464954.

16.   Schmitt FA, Nelson PT, Abner E, Scheff S, Jicha GA, Smith C, Cooper G, Mendiondo M, Danner DD, Van Eldik LJ, Caban-Holt A, Lovell MA, Kryscio RJ. University of Kentucky Sanders-Brown healthy brain aging volunteers: donor characteristics, procedures and neuropathology. Curr Alzheimer Res, 9:724-733, Published 2012, PMC3409295.

17.   Swaminathan S, Huentelman MJ, Corneveaux JJ, Myers AJ, Faber KM, Foroud T, Mayeux R, Shen L, Kim S, Turk M, Hardy J, Reiman EM, Saykin AJ. Analysis of copy number variation in Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. PLoS One, 7:e50640, Published 2012, PMC3515604.

18.   Gilman S, Koeppe RA, Nan B, Wang CN, Wang X, Junck L, Chervin RD, Consens F, Bhaumik A. Cerebral cortical and subcortical cholinergic deficits in parkinsonian syndromes. Neurology, 74:1416-1423, Published 2010, PMC2871002.

19.   Roe CM, Mintun MA, Ghoshal N, Williams MM, Grant EA, Marcus DS, Morris JC. Alzheimer disease identification using amyloid imaging and reserve variables: proof of concept. Neurology, 75:42-48, Published 2010, PMC2906402.

20.   Lopez, OL, Becker JT, Wahed AS, Saxton J, Sweet RA, Wolk DA, Klunk W, Dekosky ST. Long-term effects of the concomitant use of memantine with cholinesterase inhibition in Alzheimer disease. J Neurol Neurosurg Psychiatry, 80:600-607, Published 2009, PMC2823571.

21.   Salloway S, Sperling R, Gilman S, Fox NC, Blennow K, Raskind M, Sabbagh M, Honig LS, Doody R, van Dyck CH, Mulnard R, Barakos J, Gregg KM, Liu E, Lieberburg I, Schenk D, Black R, Grundman M. A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease. Neurology, 73:2061-2070, Published 2009, PMC2790221.

22.   Mukherjee O, Wang J, Gitcho M, Chakraverty S, Taylor-Reinwald L, Shears S, Kauwe JS, Norton J, Levitch D, Bigio EH, Hatanpaa KJ, White CL, Morris JC, Cairns NJ, Goate A. Molecular characterization of novel progranulin (GRN) mutations in frontotemporal dementia. Hum Mutat, 29:512-521, Published 2008, PMC2756561.

23.   Mackenzie IR, Bigio EH, Ince PG, Geser F, Neumann M, Cairns NJ, Kwong LK, Forman MS, Ravits J, Stewart H, Eisen A, McClusky L, Kretzschmar HA, Monoranu CM, Highley JR, Kirby J, Siddique T, Shaw PJ, Lee VM, Trojanowski JQ. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Ann Neurol, 61:427-434, Published 2007.

24.   Rosenberg RN. Translational research on the way to effective therapy for Alzheimer disease. Arch Gen Psychiatry, 62:1186-1192, Published 2005.



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